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The map label for this gene is nrdD [H]

Identifier: 74318189

GI number: 74318189

Start: 2255712

End: 2257742

Strand: Reverse

Name: nrdD [H]

Synonym: Tbd_2171

Alternate gene names: 74318189

Gene position: 2257742-2255712 (Counterclockwise)

Preceding gene: 74318196

Following gene: 74318188

Centisome position: 77.59

GC content: 64.3

Gene sequence:

>2031_bases
ATGACGGATAGAGGTCGCGACACGGTTACGGTTTCAGCGCTGCGCGAGGTGCTCAAGCGCGACGGGCGGCGGGCGCCCTT
CGACGCCGGAAAGATTCGCTCGGCGCTCCTGCGCGCGGGGCAGGCGAGCGGCGAATTCGGCGGCGACGAAGCCGACCTGC
TGACCGCCCAGGTGGTCAAGGTGCTCGCGCACAGCTTCCGCAACACCCCGCCCGACATCGAGCGCATCCAGGACGTCGTC
GAGCAGAGCCTGATCGCATCCAACCATTTCCAGACCGCGCGCGCCTACATCGCCTACCGCGAAAGCCACAAGAAGCTGCG
CGAGGACCGCAAGACCGTCGTCGACGTCGAAGCGTCCATCAACGAGTACCTCTCGCGCCAGGACTGGCGCGTCAACGCCA
ACGCCAACCAGGGCTACTCGCTCGGCGGCCTGATCCTCAACGTCTCGGGCAAGGTCGTCGCGAACTACTGGCTCAACCAC
GTCTATCCGCCCGAGCTTGGCGAAGCCCACCGCGACGGCTCGATCCACGTCCACGACCTCGACATGCTGGCCGGCTACTG
CGCCGGCTGGTCGCTGCGCACGCTACTCCACGAGGGCTTGAACGGTGTGCCCGGCAAGGTCGAGGCGGGGCCGCCCAAGC
ACATGTCGTCCGCTGTCGGGCAGATCGTCAATTTTCTCGGCACGCTGCAGAACGAGTGGGCCGGCGCGCAGGCGTTCTCG
TCCTTCGACACCTACATGGCGCCCTTCATCCGCAATGACCGGATGAGTTACGCAGAGGTTCGCCAGTGCATCCAGGAATT
GATCTACAACCTCAACGTGCCGTCGCGCTGGGGTACGCAGACGCCGTTCACCAACCTGACCTTCGACTGGACCTGCCCGG
AGGATCTGCGCGAGCAGGTGCCGGTGATCGGCGGCAAGGAAATGCCCTTCACCTACGGCGAGCTGCAGGTCGAGATGGAC
ATGATCAACCGCGCCTACATCGAGGTCATGACGACCGGCGACGCCAAGGGCCGCGTCTTCACCTTCCCGATCCCGACCTA
CAACATGACGCCGGACTTTCCCTGGGAATCGGAAAACGCCGGCCGCCTGTTCGCGATGACGGCACGCTACGGCCTGCCGT
ACTTCCAGAATTTCATCAATTCGGAAATGAAGCCGAACCACATCCGCTCGATGTGCTGCCGCCTGCAGCTCGACCTGCGC
GAACTCCTCAAGCGTGGAAACGGCCTCTTCGGCTCGGCCGAGCAGACCGGATCGGTCGGTGTCGTCACGGTCAACTGCGC
GCGCCTGGGCTACGAGTACAAAGGCGACGAGGCGGGCCTGCTGCGCCGTCTCGACGCCTTGCTCGACATGGCGAGGAACG
GCCTCGAGATCAAGCGCAAGGAAATCCAGCGCCTGATGGACAACGGCCTCTTCCCCTACACCAAGCGTTATCTCGGCACG
CTGCGCAATCACTTCTCGACTGTCGGCGTCAACGGCGTCAATGAGATGATCCGCAACTTCACCGCGGATGAGCACGACAT
CACCACGGTATGGGGCCACGACTTCGCGGTGCGCCTGCTCGACCACATCCGTGGCCGGATCGCGGCCTTCCAGGAAGAGA
CCGGCCACATGTACAACCTCGAGGCGACGCCGGCCGAAGGCACGACCTACCGCTTCGCGAAGGAAGACGCCAAGCGCTAT
CCGGGCATCCTGCAGGCCGGCGCCGAGGGCGCGCCGTATTACACCAACTCGACGCAGCTTCCGGTCGGCTTCACCGACGA
CGCGTTCGAGGCGCTCGAGCGCCAGGACGAGCTGCAGCGCAAGTACACCGGCGGCACCGTGCTGCATCTCTACATGTCGG
AGCACATCTCGTCGGCCGAGGCGTGCAAGAACCTCGTGCGCCGCTCGCTCGAGCGCTTCAGCCTGCCCTACATCACGATC
ACGCCCACTTTCTCGATCTGTCCCAAACATGGCTACCTCGCCGGCGAACACGAGTTCTGTCCGAAGTGCGACGAGGAAGC
CCTGTCGCGCAAGCGTGTTGTTTCAGCCTAA

Upstream 100 bases:

>100_bases
TAACAGGACAAGACAACCTGAAATTCATCTTGACCTTTAATCAACATGTTGTATCGTTACGCCGTGGTTGCCACAAAATA
TTGATACCGAGGAGAAACTC

Downstream 100 bases:

>100_bases
ACCCAAGGAGACGAAGATGAACGATATGACAATCCCCCACAGCCTCGACGCCGCGGCCCTCAAGGACGAGGAGCGCACGC
GCTGCGAAGTCTGGACCCGC

Product: anaerobic ribonucleoside triphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 676; Mature: 675

Protein sequence:

>676_residues
MTDRGRDTVTVSALREVLKRDGRRAPFDAGKIRSALLRAGQASGEFGGDEADLLTAQVVKVLAHSFRNTPPDIERIQDVV
EQSLIASNHFQTARAYIAYRESHKKLREDRKTVVDVEASINEYLSRQDWRVNANANQGYSLGGLILNVSGKVVANYWLNH
VYPPELGEAHRDGSIHVHDLDMLAGYCAGWSLRTLLHEGLNGVPGKVEAGPPKHMSSAVGQIVNFLGTLQNEWAGAQAFS
SFDTYMAPFIRNDRMSYAEVRQCIQELIYNLNVPSRWGTQTPFTNLTFDWTCPEDLREQVPVIGGKEMPFTYGELQVEMD
MINRAYIEVMTTGDAKGRVFTFPIPTYNMTPDFPWESENAGRLFAMTARYGLPYFQNFINSEMKPNHIRSMCCRLQLDLR
ELLKRGNGLFGSAEQTGSVGVVTVNCARLGYEYKGDEAGLLRRLDALLDMARNGLEIKRKEIQRLMDNGLFPYTKRYLGT
LRNHFSTVGVNGVNEMIRNFTADEHDITTVWGHDFAVRLLDHIRGRIAAFQEETGHMYNLEATPAEGTTYRFAKEDAKRY
PGILQAGAEGAPYYTNSTQLPVGFTDDAFEALERQDELQRKYTGGTVLHLYMSEHISSAEACKNLVRRSLERFSLPYITI
TPTFSICPKHGYLAGEHEFCPKCDEEALSRKRVVSA

Sequences:

>Translated_676_residues
MTDRGRDTVTVSALREVLKRDGRRAPFDAGKIRSALLRAGQASGEFGGDEADLLTAQVVKVLAHSFRNTPPDIERIQDVV
EQSLIASNHFQTARAYIAYRESHKKLREDRKTVVDVEASINEYLSRQDWRVNANANQGYSLGGLILNVSGKVVANYWLNH
VYPPELGEAHRDGSIHVHDLDMLAGYCAGWSLRTLLHEGLNGVPGKVEAGPPKHMSSAVGQIVNFLGTLQNEWAGAQAFS
SFDTYMAPFIRNDRMSYAEVRQCIQELIYNLNVPSRWGTQTPFTNLTFDWTCPEDLREQVPVIGGKEMPFTYGELQVEMD
MINRAYIEVMTTGDAKGRVFTFPIPTYNMTPDFPWESENAGRLFAMTARYGLPYFQNFINSEMKPNHIRSMCCRLQLDLR
ELLKRGNGLFGSAEQTGSVGVVTVNCARLGYEYKGDEAGLLRRLDALLDMARNGLEIKRKEIQRLMDNGLFPYTKRYLGT
LRNHFSTVGVNGVNEMIRNFTADEHDITTVWGHDFAVRLLDHIRGRIAAFQEETGHMYNLEATPAEGTTYRFAKEDAKRY
PGILQAGAEGAPYYTNSTQLPVGFTDDAFEALERQDELQRKYTGGTVLHLYMSEHISSAEACKNLVRRSLERFSLPYITI
TPTFSICPKHGYLAGEHEFCPKCDEEALSRKRVVSA
>Mature_675_residues
TDRGRDTVTVSALREVLKRDGRRAPFDAGKIRSALLRAGQASGEFGGDEADLLTAQVVKVLAHSFRNTPPDIERIQDVVE
QSLIASNHFQTARAYIAYRESHKKLREDRKTVVDVEASINEYLSRQDWRVNANANQGYSLGGLILNVSGKVVANYWLNHV
YPPELGEAHRDGSIHVHDLDMLAGYCAGWSLRTLLHEGLNGVPGKVEAGPPKHMSSAVGQIVNFLGTLQNEWAGAQAFSS
FDTYMAPFIRNDRMSYAEVRQCIQELIYNLNVPSRWGTQTPFTNLTFDWTCPEDLREQVPVIGGKEMPFTYGELQVEMDM
INRAYIEVMTTGDAKGRVFTFPIPTYNMTPDFPWESENAGRLFAMTARYGLPYFQNFINSEMKPNHIRSMCCRLQLDLRE
LLKRGNGLFGSAEQTGSVGVVTVNCARLGYEYKGDEAGLLRRLDALLDMARNGLEIKRKEIQRLMDNGLFPYTKRYLGTL
RNHFSTVGVNGVNEMIRNFTADEHDITTVWGHDFAVRLLDHIRGRIAAFQEETGHMYNLEATPAEGTTYRFAKEDAKRYP
GILQAGAEGAPYYTNSTQLPVGFTDDAFEALERQDELQRKYTGGTVLHLYMSEHISSAEACKNLVRRSLERFSLPYITIT
PTFSICPKHGYLAGEHEFCPKCDEEALSRKRVVSA

Specific function: Unknown

COG id: COG1328

COG function: function code F; Oxygen-sensitive ribonucleoside-triphosphate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glycine radical domain [H]

Homologues:

Organism=Escherichia coli, GI1790686, Length=721, Percent_Identity=24.2718446601942, Blast_Score=137, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR001150
- InterPro:   IPR019777
- InterPro:   IPR012833 [H]

Pfam domain/function: PF03477 ATP-cone; PF01228 Gly_radical [H]

EC number: =1.17.4.2 [H]

Molecular weight: Translated: 76156; Mature: 76025

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRGRDTVTVSALREVLKRDGRRAPFDAGKIRSALLRAGQASGEFGGDEADLLTAQVVK
CCCCCCCCEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
VLAHSFRNTPPDIERIQDVVEQSLIASNHFQTARAYIAYRESHKKLREDRKTVVDVEASI
HHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHH
NEYLSRQDWRVNANANQGYSLGGLILNVSGKVVANYWLNHVYPPELGEAHRDGSIHVHDL
HHHHCCCCCEEECCCCCCCEECCEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEHH
DMLAGYCAGWSLRTLLHEGLNGVPGKVEAGPPKHMSSAVGQIVNFLGTLQNEWAGAQAFS
HHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
SFDTYMAPFIRNDRMSYAEVRQCIQELIYNLNVPSRWGTQTPFTNLTFDWTCPEDLREQV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCHHHHHCC
PVIGGKEMPFTYGELQVEMDMINRAYIEVMTTGDAKGRVFTFPIPTYNMTPDFPWESENA
CCCCCCCCCCCCCHHEEHHHHHCCEEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCC
GRLFAMTARYGLPYFQNFINSEMKPNHIRSMCCRLQLDLRELLKRGNGLFGSAEQTGSVG
CEEEEEHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
VVTVNCARLGYEYKGDEAGLLRRLDALLDMARNGLEIKRKEIQRLMDNGLFPYTKRYLGT
EEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHH
LRNHFSTVGVNGVNEMIRNFTADEHDITTVWGHDFAVRLLDHIRGRIAAFQEETGHMYNL
HHHHHHHCCCCHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEE
EATPAEGTTYRFAKEDAKRYPGILQAGAEGAPYYTNSTQLPVGFTDDAFEALERQDELQR
ECCCCCCCEEEHHHHHHHHCCCHHHCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHH
KYTGGTVLHLYMSEHISSAEACKNLVRRSLERFSLPYITITPTFSICPKHGYLAGEHEFC
HHCCCCEEEEEHHHHCCHHHHHHHHHHHHHHHHCCCEEEECCCCEECCCCCCCCCCCCCC
PKCDEEALSRKRVVSA
CCCCHHHHHHHHHCCC
>Mature Secondary Structure 
TDRGRDTVTVSALREVLKRDGRRAPFDAGKIRSALLRAGQASGEFGGDEADLLTAQVVK
CCCCCCCEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
VLAHSFRNTPPDIERIQDVVEQSLIASNHFQTARAYIAYRESHKKLREDRKTVVDVEASI
HHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHH
NEYLSRQDWRVNANANQGYSLGGLILNVSGKVVANYWLNHVYPPELGEAHRDGSIHVHDL
HHHHCCCCCEEECCCCCCCEECCEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEHH
DMLAGYCAGWSLRTLLHEGLNGVPGKVEAGPPKHMSSAVGQIVNFLGTLQNEWAGAQAFS
HHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
SFDTYMAPFIRNDRMSYAEVRQCIQELIYNLNVPSRWGTQTPFTNLTFDWTCPEDLREQV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCHHHHHCC
PVIGGKEMPFTYGELQVEMDMINRAYIEVMTTGDAKGRVFTFPIPTYNMTPDFPWESENA
CCCCCCCCCCCCCHHEEHHHHHCCEEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCC
GRLFAMTARYGLPYFQNFINSEMKPNHIRSMCCRLQLDLRELLKRGNGLFGSAEQTGSVG
CEEEEEHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
VVTVNCARLGYEYKGDEAGLLRRLDALLDMARNGLEIKRKEIQRLMDNGLFPYTKRYLGT
EEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHH
LRNHFSTVGVNGVNEMIRNFTADEHDITTVWGHDFAVRLLDHIRGRIAAFQEETGHMYNL
HHHHHHHCCCCHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEE
EATPAEGTTYRFAKEDAKRYPGILQAGAEGAPYYTNSTQLPVGFTDDAFEALERQDELQR
ECCCCCCCEEEHHHHHHHHCCCHHHCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHH
KYTGGTVLHLYMSEHISSAEACKNLVRRSLERFSLPYITITPTFSICPKHGYLAGEHEFC
HHCCCCEEEEEHHHHCCHHHHHHHHHHHHHHHHCCCEEEECCCCEECCCCCCCCCCCCCC
PKCDEEALSRKRVVSA
CCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8421692; 7610040; 9278503; 8083158; 7852304 [H]