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The map label for this gene is ychE [H]

Identifier: 74318142

GI number: 74318142

Start: 2212503

End: 2213150

Strand: Reverse

Name: ychE [H]

Synonym: Tbd_2124

Alternate gene names: 74318142

Gene position: 2213150-2212503 (Counterclockwise)

Preceding gene: 74318143

Following gene: 74318141

Centisome position: 76.06

GC content: 65.9

Gene sequence:

>648_bases
ATGATGCATGACATGGACCTCCTCGAACTGCTGAAGGCGGCGCTCGCGCTGTTCGCGATCGTCGATCCCGTCGGTGTCAT
CCCGATCTTTCTGATGGCGACGCACGGCTTCACGCTTACGCAAAGTCGCGCGGCCGCGCGCATCGCGGCGCTGACGGTGC
TTGGCGTGCTGACGATCTTCGCGTTCGCCGGTGAAACGCTGCTGACCTTCTTCGGAATCCGGCTCGCGGCGTTCTCGGTC
GCCGGCGGTTTGCTGCTTCTTTTGCTGGCGCTGTCGATGGTCGAGGCGCACGTCAGCCCGCAGCGGCAGACGCAGGACGA
GGCCGTCGAGGCGGAAGAGAAAGACTCGGTCGGAGTCGTGCCGCTTGGCGTCCCGCTTCTCGCCGGCCCTGGCGCGATCA
CCCACGTCATCGTCGCCGCCGGCGCACTCGAGGGCCACACGCTGCAGCGTGGCCTGCTGCTGCTACCGGTCGGGCTCGTC
GCGCTGTCGGTATGGCTCGCTTTCCGCGCCGCGCCCGTGATCGCGAAGCGACTCGGAAAAACCGGCATTCACGTCGTCAC
CCGCTTGATGGGTCTGATCATCGCGGCGATCTCGATCGAGATGATCGCCCGCGGTCTCGGTGAACTGTTTCCGGGCCTGC
TAACCTGA

Upstream 100 bases:

>100_bases
CCGCCCGCTCACCAAATTCGAGCAGCGCGGGATCCGGCTCGGCCACGGCGTCTGGGACCTGGTTTTCCGCAGGCGCTGAA
GCACGACATGTCATGTGGCT

Downstream 100 bases:

>100_bases
CTCAAGCGCCGCGGCGCCGGGCAAGCCGGACGACCTATAGTGAAGCGGTGTAGTGACCCGCGGCAATGACCGCAGCTCAC
GCGCTGTAGACATCAAGCAA

Product: multiple antibiotic resistance (MarC)-like proteins

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MMHDMDLLELLKAALALFAIVDPVGVIPIFLMATHGFTLTQSRAAARIAALTVLGVLTIFAFAGETLLTFFGIRLAAFSV
AGGLLLLLLALSMVEAHVSPQRQTQDEAVEAEEKDSVGVVPLGVPLLAGPGAITHVIVAAGALEGHTLQRGLLLLPVGLV
ALSVWLAFRAAPVIAKRLGKTGIHVVTRLMGLIIAAISIEMIARGLGELFPGLLT

Sequences:

>Translated_215_residues
MMHDMDLLELLKAALALFAIVDPVGVIPIFLMATHGFTLTQSRAAARIAALTVLGVLTIFAFAGETLLTFFGIRLAAFSV
AGGLLLLLLALSMVEAHVSPQRQTQDEAVEAEEKDSVGVVPLGVPLLAGPGAITHVIVAAGALEGHTLQRGLLLLPVGLV
ALSVWLAFRAAPVIAKRLGKTGIHVVTRLMGLIIAAISIEMIARGLGELFPGLLT
>Mature_215_residues
MMHDMDLLELLKAALALFAIVDPVGVIPIFLMATHGFTLTQSRAAARIAALTVLGVLTIFAFAGETLLTFFGIRLAAFSV
AGGLLLLLLALSMVEAHVSPQRQTQDEAVEAEEKDSVGVVPLGVPLLAGPGAITHVIVAAGALEGHTLQRGLLLLPVGLV
ALSVWLAFRAAPVIAKRLGKTGIHVVTRLMGLIIAAISIEMIARGLGELFPGLLT

Specific function: Unknown

COG id: COG2095

COG function: function code U; Multiple antibiotic transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0056 (marC) family [H]

Homologues:

Organism=Escherichia coli, GI1787494, Length=211, Percent_Identity=38.8625592417062, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1787809, Length=197, Percent_Identity=26.3959390862944, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789842, Length=201, Percent_Identity=31.3432835820896, Blast_Score=78, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002771 [H]

Pfam domain/function: PF01914 MarC [H]

EC number: NA

Molecular weight: Translated: 22419; Mature: 22419

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMHDMDLLELLKAALALFAIVDPVGVIPIFLMATHGFTLTQSRAAARIAALTVLGVLTIF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
AFAGETLLTFFGIRLAAFSVAGGLLLLLLALSMVEAHVSPQRQTQDEAVEAEEKDSVGVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEE
PLGVPLLAGPGAITHVIVAAGALEGHTLQRGLLLLPVGLVALSVWLAFRAAPVIAKRLGK
ECCCHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TGIHVVTRLMGLIIAAISIEMIARGLGELFPGLLT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MMHDMDLLELLKAALALFAIVDPVGVIPIFLMATHGFTLTQSRAAARIAALTVLGVLTIF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
AFAGETLLTFFGIRLAAFSVAGGLLLLLLALSMVEAHVSPQRQTQDEAVEAEEKDSVGVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEE
PLGVPLLAGPGAITHVIVAAGALEGHTLQRGLLLLPVGLVALSVWLAFRAAPVIAKRLGK
ECCCHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TGIHVVTRLMGLIIAAISIEMIARGLGELFPGLLT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2015910; 9097039; 9278503 [H]