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The map label for this gene is hfq

Identifier: 74317551

GI number: 74317551

Start: 1618264

End: 1618506

Strand: Direct

Name: hfq

Synonym: Tbd_1533

Alternate gene names: 74317551

Gene position: 1618264-1618506 (Clockwise)

Preceding gene: 74317550

Following gene: 74317555

Centisome position: 55.61

GC content: 58.02

Gene sequence:

>243_bases
ATGGCCAAAGAACACAATCATCTGCAAGACGTTTTTCTCAACACCCTGCGCAAGGAACGCATCCCGGTCTCGGTGTTCCT
CGTCAACGGGATCAAGCTGATGGGGCGGATCGAGTCTTTCGATCAGTTCGTCGTGCTGCTCAAGGGCCAGGACCAGGCCG
CACAGATGATTTTCAAGCACGCCATCTCGACGATTTCGCCGTCGCGCGAAGTCGTGCTGCCGCAGCGCGACGCCGAAGCC
TGA

Upstream 100 bases:

>100_bases
ATGCCGTGACGGCCGCGCGTGCGAACGCCAAAGTCGAGTAATCGCTACTAATATTAAGCAGGGCCTCGCCCGCCCTGCCT
TTTCCTACAGGGAGCCGCAC

Downstream 100 bases:

>100_bases
GGGTCTACTCGACGTGGGCGGCGAGCAACGCCGTCGCCGCATGGGCATCGACCAGCGCCACCGCGCCGCCGCGATACGCC
TGCTTGTGCCGGGCCGGAAT

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 80; Mature: 79

Protein sequence:

>80_residues
MAKEHNHLQDVFLNTLRKERIPVSVFLVNGIKLMGRIESFDQFVVLLKGQDQAAQMIFKHAISTISPSREVVLPQRDAEA

Sequences:

>Translated_80_residues
MAKEHNHLQDVFLNTLRKERIPVSVFLVNGIKLMGRIESFDQFVVLLKGQDQAAQMIFKHAISTISPSREVVLPQRDAEA
>Mature_79_residues
AKEHNHLQDVFLNTLRKERIPVSVFLVNGIKLMGRIESFDQFVVLLKGQDQAAQMIFKHAISTISPSREVVLPQRDAEA

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family

Homologues:

Organism=Escherichia coli, GI1790614, Length=71, Percent_Identity=66.1971830985916, Blast_Score=97, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFQ_THIDA (Q3SIN9)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_315291.1
- ProteinModelPortal:   Q3SIN9
- SMR:   Q3SIN9
- STRING:   Q3SIN9
- GeneID:   3672012
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_1533
- NMPDR:   fig|292415.3.peg.1533
- eggNOG:   COG1923
- HOGENOM:   HBG645207
- OMA:   KAPFNIQ
- PhylomeDB:   Q3SIN9
- BioCyc:   TDEN292415:TBD_1533-MONOMER
- HAMAP:   MF_00436
- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163
- TIGRFAMs:   TIGR02383

Pfam domain/function: PF01423 LSM; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 9102; Mature: 8971

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKEHNHLQDVFLNTLRKERIPVSVFLVNGIKLMGRIESFDQFVVLLKGQDQAAQMIFKH
CCCCCHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
AISTISPSREVVLPQRDAEA
HHHHCCCCCCEECCCCCCCC
>Mature Secondary Structure 
AKEHNHLQDVFLNTLRKERIPVSVFLVNGIKLMGRIESFDQFVVLLKGQDQAAQMIFKH
CCCCHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
AISTISPSREVVLPQRDAEA
HHHHCCCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA