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The map label for this gene is infA2

Identifier: 74317481

GI number: 74317481

Start: 1548071

End: 1548334

Strand: Direct

Name: infA2

Synonym: Tbd_1463

Alternate gene names: 74317481

Gene position: 1548071-1548334 (Clockwise)

Preceding gene: 74317480

Following gene: 74317483

Centisome position: 53.2

GC content: 60.98

Gene sequence:

>264_bases
ATGGCAAAAGAAGAAGTTATCGAAATGGAAGGCGTCGTCAACGAGGTCCTGCCGCAGACCCGCTTCCGCGTCACGCTCGA
CAATGGCTTCGAGATCACGGCCTATGCCTCCGGCAAGATGCGCAAGCACCGCATCCGCATTCTCGCGGGCGACAAGGTCA
CGGTCGAGATGTCCCCCTACGACCTGACCAAGGGCAGGATCAACTTCCGCCACAAGGACGCCCATCAGGCGCCGAGACCC
ACGGTCGCCCGCCGCTACAACTAA

Upstream 100 bases:

>100_bases
TGGCTTTCCACCGCGCGTCAGCGCGGCCGCACCACCGGCACCGCGAACTTTCGCACCTGCCCGGGCAGCGTCTCGCGCCG
CCCTTCACGAGGAACACGCA

Downstream 100 bases:

>100_bases
GTCCCTTCGGAACCCGCTTCCGGGCTCACCAGCGGAGTTCGAGGCGGCCGTCCGGTCCCGGTTCCACGCGGGTGCCGAGC
ATCCGCCCCTCGCGATCCAG

Product: translation initiation factor IF-1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 87; Mature: 86

Protein sequence:

>87_residues
MAKEEVIEMEGVVNEVLPQTRFRVTLDNGFEITAYASGKMRKHRIRILAGDKVTVEMSPYDLTKGRINFRHKDAHQAPRP
TVARRYN

Sequences:

>Translated_87_residues
MAKEEVIEMEGVVNEVLPQTRFRVTLDNGFEITAYASGKMRKHRIRILAGDKVTVEMSPYDLTKGRINFRHKDAHQAPRP
TVARRYN
>Mature_86_residues
AKEEVIEMEGVVNEVLPQTRFRVTLDNGFEITAYASGKMRKHRIRILAGDKVTVEMSPYDLTKGRINFRHKDAHQAPRPT
VARRYN

Specific function: No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain

Homologues:

Organism=Escherichia coli, GI1787110, Length=72, Percent_Identity=66.6666666666667, Blast_Score=99, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF12_THIDA (Q3SIV9)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_315221.1
- ProteinModelPortal:   Q3SIV9
- SMR:   Q3SIV9
- STRING:   Q3SIV9
- GeneID:   3673576
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_1463
- NMPDR:   fig|292415.3.peg.1463
- eggNOG:   COG0361
- HOGENOM:   HBG286099
- OMA:   EILAHSC
- ProtClustDB:   PRK12442
- BioCyc:   TDEN292415:TBD_1463-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00075
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR022967
- InterPro:   IPR006196
- InterPro:   IPR004368
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00316
- TIGRFAMs:   TIGR00008

Pfam domain/function: PF01176 eIF-1a; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 10057; Mature: 9926

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: PS50832 S1_IF1_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKEEVIEMEGVVNEVLPQTRFRVTLDNGFEITAYASGKMRKHRIRILAGDKVTVEMSPY
CCCHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCCEEEEEEEECCEEEEEECCC
DLTKGRINFRHKDAHQAPRPTVARRYN
CCCCCEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKEEVIEMEGVVNEVLPQTRFRVTLDNGFEITAYASGKMRKHRIRILAGDKVTVEMSPY
CCHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCCEEEEEEEECCEEEEEECCC
DLTKGRINFRHKDAHQAPRPTVARRYN
CCCCCEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA