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The map label for this gene is uidR [H]

Identifier: 74317437

GI number: 74317437

Start: 1509746

End: 1510408

Strand: Direct

Name: uidR [H]

Synonym: Tbd_1419

Alternate gene names: 74317437

Gene position: 1509746-1510408 (Clockwise)

Preceding gene: 74317428

Following gene: 74317439

Centisome position: 51.88

GC content: 68.63

Gene sequence:

>663_bases
ATGAATCCGGAGACCCGCATGACCGCCGCCCCCCCGATTCCCGACGCCACGCGCGCCGACGCCCGCCGCAGCCAGATCCG
TGCGGCCGCGGCCGAGTGCTTCCGGCAGCATGGCTTCCACGGCACGAGCATCGCGCAAATATCCAAGGCCGCGGGCATGA
GCACGGGCCACATCTACCACTATTTCGAGAACAAGGAAGCGATCATCGCCGAGATCGTTGCCCAGGATCTCGAGCGCTTG
CTGACGCTGACCGCCGAGCTGCGCGCTGCGAGCGACGTCAAGGCCGCGATGATCGAGCGCGCCGTGGAAGGCGTGCAGCA
GAATCTCGATCCGGCTCACGCGGGCCTGCAGCTCGAGGTCGTCGCCGAAGCCGCACGCAATCCGCGCATTGCGCACATCG
TGCGCGCGGCCGACCGCCAGTGTCGGGAAAGCCTGCTGCAGACGATTCGAACGCTGCGACGGGCCGCCGGGCATCAGGAC
AGCGAGGCGACGCTCGCGGGCATGGCCGAGGCGATCTCGGCGATGTTCGAAGGCCTGCGCATACGCGCGATCCGCAACCC
CGACATCGACCGCGATGTCGTCGTGCAAATGTTCCGGCGCATGGTCGGCGACCTGCTCTCCCAGGCGCCGCAACCGCCGC
CCCGCGGTCGGCGCGACACATAG

Upstream 100 bases:

>100_bases
AGGCCGGTGACTGGGCGAAGCACTGTTCTAGAATGAACGTTCAATCTATACTAGAAGGCCTTCCGGCGCAAGATTCGGCG
CTTCTCGAATCGCCACGCCC

Downstream 100 bases:

>100_bases
AAAAATGCCCCCGAAGCGGGGGCATCGTTCGACACCCGGGCGAGCCCGGGATGCGATCACTTGATGTTCTTCATTTCGGC
TTCGACCATCTTGACGACGT

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: Uid operon repressor [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MNPETRMTAAPPIPDATRADARRSQIRAAAAECFRQHGFHGTSIAQISKAAGMSTGHIYHYFENKEAIIAEIVAQDLERL
LTLTAELRAASDVKAAMIERAVEGVQQNLDPAHAGLQLEVVAEAARNPRIAHIVRAADRQCRESLLQTIRTLRRAAGHQD
SEATLAGMAEAISAMFEGLRIRAIRNPDIDRDVVVQMFRRMVGDLLSQAPQPPPRGRRDT

Sequences:

>Translated_220_residues
MNPETRMTAAPPIPDATRADARRSQIRAAAAECFRQHGFHGTSIAQISKAAGMSTGHIYHYFENKEAIIAEIVAQDLERL
LTLTAELRAASDVKAAMIERAVEGVQQNLDPAHAGLQLEVVAEAARNPRIAHIVRAADRQCRESLLQTIRTLRRAAGHQD
SEATLAGMAEAISAMFEGLRIRAIRNPDIDRDVVVQMFRRMVGDLLSQAPQPPPRGRRDT
>Mature_220_residues
MNPETRMTAAPPIPDATRADARRSQIRAAAAECFRQHGFHGTSIAQISKAAGMSTGHIYHYFENKEAIIAEIVAQDLERL
LTLTAELRAASDVKAAMIERAVEGVQQNLDPAHAGLQLEVVAEAARNPRIAHIVRAADRQCRESLLQTIRTLRRAAGHQD
SEATLAGMAEAISAMFEGLRIRAIRNPDIDRDVVVQMFRRMVGDLLSQAPQPPPRGRRDT

Specific function: Repressor for the uidRABC (gusRABC) operon [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787904, Length=134, Percent_Identity=32.8358208955224, Blast_Score=68, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 24187; Mature: 24187

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPETRMTAAPPIPDATRADARRSQIRAAAAECFRQHGFHGTSIAQISKAAGMSTGHIYH
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEE
YFENKEAIIAEIVAQDLERLLTLTAELRAASDVKAAMIERAVEGVQQNLDPAHAGLQLEV
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHH
VAEAARNPRIAHIVRAADRQCRESLLQTIRTLRRAAGHQDSEATLAGMAEAISAMFEGLR
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
IRAIRNPDIDRDVVVQMFRRMVGDLLSQAPQPPPRGRRDT
EEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNPETRMTAAPPIPDATRADARRSQIRAAAAECFRQHGFHGTSIAQISKAAGMSTGHIYH
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEE
YFENKEAIIAEIVAQDLERLLTLTAELRAASDVKAAMIERAVEGVQQNLDPAHAGLQLEV
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHH
VAEAARNPRIAHIVRAADRQCRESLLQTIRTLRRAAGHQDSEATLAGMAEAISAMFEGLR
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
IRAIRNPDIDRDVVVQMFRRMVGDLLSQAPQPPPRGRRDT
EEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]