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The map label for this gene is hflX [H]

Identifier: 74317381

GI number: 74317381

Start: 1442923

End: 1444299

Strand: Direct

Name: hflX [H]

Synonym: Tbd_1363

Alternate gene names: 74317381

Gene position: 1442923-1444299 (Clockwise)

Preceding gene: 74317359

Following gene: 74317383

Centisome position: 49.59

GC content: 66.3

Gene sequence:

>1377_bases
ATGCCCCTTCAAGTAGAAGACAAACCCGCGTACGCGGTCGTCGCCGCCGTTCAGTTGCCTCAGGTCAGCGACCTCGAGTT
CGAGGCGTCGTTGACCGAATTACGGGAGCTGGCCAAGACCCTGGGGTTCACAGTCATCCGCACGTTCACGCAAAAGCGCC
CGGGCTTCGACACGACGGCCTATCTGGGCGTCGGCAAGCGGCAGGAACTCACGCGCTTCGTCCGCGGCGGGGAAGAAGAA
GCGGAAGCCGATCCCGCGGCGCCGTATGCCTTGCATCGCGTCGAGGGCCAGGACGATGTCTCGCCGCATCCGATCGACGT
GCTTTTCGTCGACCACGAGATTTCGCCCTCGCAGGCCCGCAACCTGGAAAACGAGGTGGGTTGTCAGGTGATGGACCGCA
CCATGGTCATCCTCGAGATCTTCCACCGCAACGCGCGCTCCCCGGCGGCACGCGCGCAGGTCGAGATCGCACGTCTGGGC
TACCTCGCGCCGCGCCTGCGCGAGGCAGCGAAACTCGCCGGGCCGCAGGGCCGGCAGCGCAGCGGGGTCGGCGGACGCGG
CGCCGGCGAATCGCACACCGAACTCGACAAGCGCAAGATCCGCGACCGCATCGCCGAACTGCAGAAGGAAATCGCCGCGA
TGGATGCGGACCGCAAGACCCAACGCGCCCGGCGGCAGGCGCACCAGGGCCTCGCCAGCGTGGCGCTGGTCGGCTATACC
AACGCCGGCAAGTCCACGCTGATGCGCGCCCTCACCGGCAGCGAAGTGCTGGTCGCCAACAAGCTCTTCGCCACCCTCGA
CACCACGGTCCGCACATTGCACCCCGAGGGCGTCCCGCGCGTCCTTGTCAGCGACACCGTCGGCTTCATCAAGAACCTGC
CGCACGGCCTGGTCGCGTCGTTCAAGTCCACGCTCGAAGAGGCACTCGATGCCTCGCTGCTGCTCCATGTCATCGACGCC
AGCGACCCTGGCTTCGTGCGGCAGATCGAAACCACCGAAGACGTGCTCGAGGAAATCGACGCGCAGGACGTGCCGCGCTT
GCGCATCTTCAACAAGATCGACCACCTCGGCGACGCCGTGGCGCAAGCCGAGCGCGAAGCCGCGCTGCGCGCAGCCTATC
CCGGCTGCATCGTCATGAGCGCCCGCCGCCCGGAAGACGTCGCGAAACTGCACGACGCGATCCTCACGTTTTTCCAGAAG
GATCTGGTCGAGGCCGAGCTGTTTCTGCCGTGGTCGGCACAGCAGCTGCGCGGCGAAATATTCGCGCGCTGCCAAGTGCT
GGAAGAACGCTCGGACGAAGACGGTGCGTTTTTCCACGTGCGCGGCGAGCAGGAGACCTTGAATGGCCTGCGCGACCAAC
TCGGCCACGCGCGATGA

Upstream 100 bases:

>100_bases
TCCAGCCGACCTAATAGGCTCCCCCGTACCCGTGCGTGCTGCGCGCTCCGGTCTGCGTTCCCGCGTACTATCTGCCCTCG
CCCCATTCCCTAGACTCACC

Downstream 100 bases:

>100_bases
AATCGGCGTGCTCACGGCGACTCCCCGCGGCCCGGTGAACGGCCGTCGCAGCCGTGCCGTGCGCGTCCTCGGCTCAGCTT
GTGGCGGCAGGTGCCCCGAC

Product: putative GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MPLQVEDKPAYAVVAAVQLPQVSDLEFEASLTELRELAKTLGFTVIRTFTQKRPGFDTTAYLGVGKRQELTRFVRGGEEE
AEADPAAPYALHRVEGQDDVSPHPIDVLFVDHEISPSQARNLENEVGCQVMDRTMVILEIFHRNARSPAARAQVEIARLG
YLAPRLREAAKLAGPQGRQRSGVGGRGAGESHTELDKRKIRDRIAELQKEIAAMDADRKTQRARRQAHQGLASVALVGYT
NAGKSTLMRALTGSEVLVANKLFATLDTTVRTLHPEGVPRVLVSDTVGFIKNLPHGLVASFKSTLEEALDASLLLHVIDA
SDPGFVRQIETTEDVLEEIDAQDVPRLRIFNKIDHLGDAVAQAEREAALRAAYPGCIVMSARRPEDVAKLHDAILTFFQK
DLVEAELFLPWSAQQLRGEIFARCQVLEERSDEDGAFFHVRGEQETLNGLRDQLGHAR

Sequences:

>Translated_458_residues
MPLQVEDKPAYAVVAAVQLPQVSDLEFEASLTELRELAKTLGFTVIRTFTQKRPGFDTTAYLGVGKRQELTRFVRGGEEE
AEADPAAPYALHRVEGQDDVSPHPIDVLFVDHEISPSQARNLENEVGCQVMDRTMVILEIFHRNARSPAARAQVEIARLG
YLAPRLREAAKLAGPQGRQRSGVGGRGAGESHTELDKRKIRDRIAELQKEIAAMDADRKTQRARRQAHQGLASVALVGYT
NAGKSTLMRALTGSEVLVANKLFATLDTTVRTLHPEGVPRVLVSDTVGFIKNLPHGLVASFKSTLEEALDASLLLHVIDA
SDPGFVRQIETTEDVLEEIDAQDVPRLRIFNKIDHLGDAVAQAEREAALRAAYPGCIVMSARRPEDVAKLHDAILTFFQK
DLVEAELFLPWSAQQLRGEIFARCQVLEERSDEDGAFFHVRGEQETLNGLRDQLGHAR
>Mature_457_residues
PLQVEDKPAYAVVAAVQLPQVSDLEFEASLTELRELAKTLGFTVIRTFTQKRPGFDTTAYLGVGKRQELTRFVRGGEEEA
EADPAAPYALHRVEGQDDVSPHPIDVLFVDHEISPSQARNLENEVGCQVMDRTMVILEIFHRNARSPAARAQVEIARLGY
LAPRLREAAKLAGPQGRQRSGVGGRGAGESHTELDKRKIRDRIAELQKEIAAMDADRKTQRARRQAHQGLASVALVGYTN
AGKSTLMRALTGSEVLVANKLFATLDTTVRTLHPEGVPRVLVSDTVGFIKNLPHGLVASFKSTLEEALDASLLLHVIDAS
DPGFVRQIETTEDVLEEIDAQDVPRLRIFNKIDHLGDAVAQAEREAALRAAYPGCIVMSARRPEDVAKLHDAILTFFQKD
LVEAELFLPWSAQQLRGEIFARCQVLEERSDEDGAFFHVRGEQETLNGLRDQLGHAR

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=151, Percent_Identity=41.7218543046358, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI310133116, Length=151, Percent_Identity=41.7218543046358, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI310124269, Length=144, Percent_Identity=40.9722222222222, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI310124267, Length=144, Percent_Identity=40.9722222222222, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI310124171, Length=144, Percent_Identity=40.9722222222222, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI310124169, Length=144, Percent_Identity=40.9722222222222, Blast_Score=100, Evalue=4e-21,
Organism=Escherichia coli, GI1790615, Length=431, Percent_Identity=36.1948955916473, Blast_Score=226, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17561038, Length=249, Percent_Identity=34.5381526104418, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24650079, Length=265, Percent_Identity=33.5849056603774, Blast_Score=109, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50608; Mature: 50477

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLQVEDKPAYAVVAAVQLPQVSDLEFEASLTELRELAKTLGFTVIRTFTQKRPGFDTTA
CCCCCCCCCCEEEEEEHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
YLGVGKRQELTRFVRGGEEEAEADPAAPYALHRVEGQDDVSPHPIDVLFVDHEISPSQAR
EECCCCHHHHHHHHHCCCHHHCCCCCCCHHHEECCCCCCCCCCCEEEEEEECCCCHHHHH
NLENEVGCQVMDRTMVILEIFHRNARSPAARAQVEIARLGYLAPRLREAAKLAGPQGRQR
CCHHHHCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SGVGGRGAGESHTELDKRKIRDRIAELQKEIAAMDADRKTQRARRQAHQGLASVALVGYT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEEC
NAGKSTLMRALTGSEVLVANKLFATLDTTVRTLHPEGVPRVLVSDTVGFIKNLPHGLVAS
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHH
FKSTLEEALDASLLLHVIDASDPGFVRQIETTEDVLEEIDAQDVPRLRIFNKIDHLGDAV
HHHHHHHHHHHHHHHHHHCCCCCCHHEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
AQAEREAALRAAYPGCIVMSARRPEDVAKLHDAILTFFQKDLVEAELFLPWSAQQLRGEI
HHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
FARCQVLEERSDEDGAFFHVRGEQETLNGLRDQLGHAR
HHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PLQVEDKPAYAVVAAVQLPQVSDLEFEASLTELRELAKTLGFTVIRTFTQKRPGFDTTA
CCCCCCCCCEEEEEEHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
YLGVGKRQELTRFVRGGEEEAEADPAAPYALHRVEGQDDVSPHPIDVLFVDHEISPSQAR
EECCCCHHHHHHHHHCCCHHHCCCCCCCHHHEECCCCCCCCCCCEEEEEEECCCCHHHHH
NLENEVGCQVMDRTMVILEIFHRNARSPAARAQVEIARLGYLAPRLREAAKLAGPQGRQR
CCHHHHCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SGVGGRGAGESHTELDKRKIRDRIAELQKEIAAMDADRKTQRARRQAHQGLASVALVGYT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEEC
NAGKSTLMRALTGSEVLVANKLFATLDTTVRTLHPEGVPRVLVSDTVGFIKNLPHGLVAS
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHH
FKSTLEEALDASLLLHVIDASDPGFVRQIETTEDVLEEIDAQDVPRLRIFNKIDHLGDAV
HHHHHHHHHHHHHHHHHHCCCCCCHHEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
AQAEREAALRAAYPGCIVMSARRPEDVAKLHDAILTFFQKDLVEAELFLPWSAQQLRGEI
HHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
FARCQVLEERSDEDGAFFHVRGEQETLNGLRDQLGHAR
HHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]