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The map label for this gene is czcB [H]

Identifier: 74317346

GI number: 74317346

Start: 1410356

End: 1411867

Strand: Reverse

Name: czcB [H]

Synonym: Tbd_1328

Alternate gene names: 74317346

Gene position: 1411867-1410356 (Counterclockwise)

Preceding gene: 74317347

Following gene: 74317345

Centisome position: 48.52

GC content: 63.29

Gene sequence:

>1512_bases
ATGAAATTCAATCCGAACAAGAAACAGGCGCTGGTTATTGCCGGGGTTCTGGCAGTCGGCGTCCTCCTCGCGGCGCTGGT
CCTCGGTACCGGCAAACCGCAGATGGAAACCGATACGCACGGCGAACCCGCTGGCCAAGCCGAGGGCGGCCGCGAAGACG
CGGGCGCACCGCAAAAAGGCCCGCACGGCGGCAAGCTTTTCACGCAGGATGGCTACGGCGTCGAGGTGACAATCTTCGAG
ACCAACGTCGAGCCGCAATTTCGCGTTTACACCTATCTGAACGACAAGCCACTGGCGCCCTCGGCGAGCGAGGTCAGCCT
CACGCTGGAGCGGCTGGGTCGCGCGCCGCAGGTATTCCGCTTTACCCCGGAAAACGATTACCTCAAGGGTGATGCCGTCG
TCGAAGAGCCGCATTCGTTCAAGGTCGGCATCGCCGCGCGGCACGGCGGAAAATCGTATCGATTTGGCTACGAGCAGGTC
GAGGCGCGGGTCGCGATGTCGGATCAGCAGGTGCAGCAAAACAAGGTCGAGATCCTCAGCGCAGGCCCGGCGCGCATTCA
GAGCGTGCTGGAGCTGATCGGCGAGATCCGTTTCAACGAAGACCGTCAGGTTCATGTCGTGCCGCGCCTCGCCGGCGTCG
TCGAGTCCGTCTCGGCCAACGCCGGCGACCGGGTCAGAAAAGGCCAGGTGCTCGCGGTGATTTTTAGCCCGGCGCTGGCT
GACCAGCGCAGTGAACTGCTCGCCGCGCAAAAACGCCTGACGCTGGCGCGCTCGACGTTCACGCGCGAGAAAAAATTGTG
GGAGGACAAAATCTCCCCCGAGCAGGATTACCTGCAAGCGCAGGCTGCCATGCAGGAAGCCGAAATCGCGGCGCAAAACG
CGCGCCAGAAACTGGCGTCGATTGGCGGCGAACTGCGCGGCAGCGGCAACCTCACACGCTACGAGATTCGTGCGCCGATC
GGCGGCGTGGTGATCGAAAAGAAAGTCTCGCTGGGCGAAACGGTGAAGGAAGACGCGACGATCTTCGTCGTCGCCGATCT
GTCCACGGTGTGGGCGGAAATGACGATTTATGCCAAGGACCTCAACACCGTGAAAGTCGGCCAGAAAGCCACTGTCAAGG
CGACCGCGTTCGAATCCGAGAGCAGTGGCGTCATTTCCTATGTGGGCGCGCTGGTGGGCGAGCAAACCCGAACGGCCAAG
GCACGCGTCGTATTACCCAACCCCCAAGGGGTCTGGCGTCCCGGCCTGCCGGTCAGTATCCGGGTGGTGTCGGGGGAGGT
CGACGTGCCGGTGGCCGTGTCCGCCGAGGCGATCCAGACCGTGCGCGGCTGGACGGTGGTATTTGGGCGCTACGGCGACC
AGTTCGAGGCCCGCCCGGTCGAACTGGGGCGCAGCGACGGCAAGTTCACCGAAATCATCAGCGGCTTGAACGCGGGCGAG
CAGTACGCCGCGAAAAACAGCTTCCTTATCAAGGCCGACATCGGCAAGTCCGGCGCGAGCCACGACCACTAG

Upstream 100 bases:

>100_bases
GCGCGCATTGGCCGAAGCGCACCGGTCGGCGGCCGAAATCGAGCGCATTCTTGGCGATACACGTCCGGCACCCGCTGCCG
TCCAACCGTAGGAACTCAAC

Downstream 100 bases:

>100_bases
GGGCAGCCATGAAACAGGTCATTGCCATCGTCCAGTCGTAGCTGCTGGAGCGGGCCGGACAGACGTTGCGCGGGCCACTT
GCCGGATGACGGCCTGATTG

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 503

Protein sequence:

>503_residues
MKFNPNKKQALVIAGVLAVGVLLAALVLGTGKPQMETDTHGEPAGQAEGGREDAGAPQKGPHGGKLFTQDGYGVEVTIFE
TNVEPQFRVYTYLNDKPLAPSASEVSLTLERLGRAPQVFRFTPENDYLKGDAVVEEPHSFKVGIAARHGGKSYRFGYEQV
EARVAMSDQQVQQNKVEILSAGPARIQSVLELIGEIRFNEDRQVHVVPRLAGVVESVSANAGDRVRKGQVLAVIFSPALA
DQRSELLAAQKRLTLARSTFTREKKLWEDKISPEQDYLQAQAAMQEAEIAAQNARQKLASIGGELRGSGNLTRYEIRAPI
GGVVIEKKVSLGETVKEDATIFVVADLSTVWAEMTIYAKDLNTVKVGQKATVKATAFESESSGVISYVGALVGEQTRTAK
ARVVLPNPQGVWRPGLPVSIRVVSGEVDVPVAVSAEAIQTVRGWTVVFGRYGDQFEARPVELGRSDGKFTEIISGLNAGE
QYAAKNSFLIKADIGKSGASHDH

Sequences:

>Translated_503_residues
MKFNPNKKQALVIAGVLAVGVLLAALVLGTGKPQMETDTHGEPAGQAEGGREDAGAPQKGPHGGKLFTQDGYGVEVTIFE
TNVEPQFRVYTYLNDKPLAPSASEVSLTLERLGRAPQVFRFTPENDYLKGDAVVEEPHSFKVGIAARHGGKSYRFGYEQV
EARVAMSDQQVQQNKVEILSAGPARIQSVLELIGEIRFNEDRQVHVVPRLAGVVESVSANAGDRVRKGQVLAVIFSPALA
DQRSELLAAQKRLTLARSTFTREKKLWEDKISPEQDYLQAQAAMQEAEIAAQNARQKLASIGGELRGSGNLTRYEIRAPI
GGVVIEKKVSLGETVKEDATIFVVADLSTVWAEMTIYAKDLNTVKVGQKATVKATAFESESSGVISYVGALVGEQTRTAK
ARVVLPNPQGVWRPGLPVSIRVVSGEVDVPVAVSAEAIQTVRGWTVVFGRYGDQFEARPVELGRSDGKFTEIISGLNAGE
QYAAKNSFLIKADIGKSGASHDH
>Mature_503_residues
MKFNPNKKQALVIAGVLAVGVLLAALVLGTGKPQMETDTHGEPAGQAEGGREDAGAPQKGPHGGKLFTQDGYGVEVTIFE
TNVEPQFRVYTYLNDKPLAPSASEVSLTLERLGRAPQVFRFTPENDYLKGDAVVEEPHSFKVGIAARHGGKSYRFGYEQV
EARVAMSDQQVQQNKVEILSAGPARIQSVLELIGEIRFNEDRQVHVVPRLAGVVESVSANAGDRVRKGQVLAVIFSPALA
DQRSELLAAQKRLTLARSTFTREKKLWEDKISPEQDYLQAQAAMQEAEIAAQNARQKLASIGGELRGSGNLTRYEIRAPI
GGVVIEKKVSLGETVKEDATIFVVADLSTVWAEMTIYAKDLNTVKVGQKATVKATAFESESSGVISYVGALVGEQTRTAK
ARVVLPNPQGVWRPGLPVSIRVVSGEVDVPVAVSAEAIQTVRGWTVVFGRYGDQFEARPVELGRSDGKFTEIISGLNAGE
QYAAKNSFLIKADIGKSGASHDH

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87081796, Length=315, Percent_Identity=26.3492063492064, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 54259; Mature: 54259

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFNPNKKQALVIAGVLAVGVLLAALVLGTGKPQMETDTHGEPAGQAEGGREDAGAPQKG
CCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PHGGKLFTQDGYGVEVTIFETNVEPQFRVYTYLNDKPLAPSASEVSLTLERLGRAPQVFR
CCCCEEEECCCCEEEEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCEEE
FTPENDYLKGDAVVEEPHSFKVGIAARHGGKSYRFGYEQVEARVAMSDQQVQQNKVEILS
ECCCCCCCCCCCEEECCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCHHHHHHCCCEEEE
AGPARIQSVLELIGEIRFNEDRQVHVVPRLAGVVESVSANAGDRVRKGQVLAVIFSPALA
CCHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHH
DQRSELLAAQKRLTLARSTFTREKKLWEDKISPEQDYLQAQAAMQEAEIAAQNARQKLAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGGELRGSGNLTRYEIRAPIGGVVIEKKVSLGETVKEDATIFVVADLSTVWAEMTIYAKD
CCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCHHCCCCEEEEEECHHHHHHHEEEEEEC
LNTVKVGQKATVKATAFESESSGVISYVGALVGEQTRTAKARVVLPNPQGVWRPGLPVSI
CCEEECCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCEEE
RVVSGEVDVPVAVSAEAIQTVRGWTVVFGRYGDQFEARPVELGRSDGKFTEIISGLNAGE
EEEECCCCCCEEECHHHHHHHCCEEEEEECCCCCCCCCHHHCCCCCCHHHHHHHCCCCCH
QYAAKNSFLIKADIGKSGASHDH
HHHCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MKFNPNKKQALVIAGVLAVGVLLAALVLGTGKPQMETDTHGEPAGQAEGGREDAGAPQKG
CCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PHGGKLFTQDGYGVEVTIFETNVEPQFRVYTYLNDKPLAPSASEVSLTLERLGRAPQVFR
CCCCEEEECCCCEEEEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCEEE
FTPENDYLKGDAVVEEPHSFKVGIAARHGGKSYRFGYEQVEARVAMSDQQVQQNKVEILS
ECCCCCCCCCCCEEECCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCHHHHHHCCCEEEE
AGPARIQSVLELIGEIRFNEDRQVHVVPRLAGVVESVSANAGDRVRKGQVLAVIFSPALA
CCHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHH
DQRSELLAAQKRLTLARSTFTREKKLWEDKISPEQDYLQAQAAMQEAEIAAQNARQKLAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGGELRGSGNLTRYEIRAPIGGVVIEKKVSLGETVKEDATIFVVADLSTVWAEMTIYAKD
CCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCHHCCCCEEEEEECHHHHHHHEEEEEEC
LNTVKVGQKATVKATAFESESSGVISYVGALVGEQTRTAKARVVLPNPQGVWRPGLPVSI
CCEEECCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCEEE
RVVSGEVDVPVAVSAEAIQTVRGWTVVFGRYGDQFEARPVELGRSDGKFTEIISGLNAGE
EEEECCCCCCEEECHHHHHHHCCEEEEEECCCCCCCCCHHHCCCCCCHHHHHHHCCCCCH
QYAAKNSFLIKADIGKSGASHDH
HHHCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]