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The map label for this gene is motA [H]

Identifier: 74317261

GI number: 74317261

Start: 1304538

End: 1305398

Strand: Direct

Name: motA [H]

Synonym: Tbd_1243

Alternate gene names: 74317261

Gene position: 1304538-1305398 (Clockwise)

Preceding gene: 74317260

Following gene: 74317262

Centisome position: 44.83

GC content: 61.67

Gene sequence:

>861_bases
TTGCTAGTCATCGTCGGATACGTCATCGTCGTCCTGAGCGTCTTCGGAGGGTTCGTGCTCGCGGGCGGCCATCTGGCCGC
GCTTTTCCAGCCGCTGGAACTCCTGATGATCGGCGGCGGCGCGATCGGCGCCTTTCTCGTCGGCAACAACAACAAGGTGA
TCAAGGCGACGCTGAAGGCCTTGCCGACCGTGCTCAAAGGCTCGAAGTACACGCGCGCGCTTTACATGGACACGCTTGCG
CTGCTCTACGAACTGCTGACCAAAATCCGCAAGGAAGGCCTGATGTCGGTCGAAGCCGACGTCGATTCCCCCGAGAGCAG
TCCGCTGTTCAGCAAGTATCCGGCGATCATGGCGGACCACCATGTCGTCGAGTTCCTGACCGACTACCTCCGGCTCATGG
TGAGCGGCAGCATGAACGCGTTCGAGATCGAAAACCTGATGGACAACGAAATCGAAACGCATCATCACGAAGGCGAGGTG
CCGGCTCACGTTATCGCGAAAATCGGCGACGGGCTGCCGGCCTTCGGTATCGTCGCGGCGGTCATGGGCGTCGTCCACAC
CATGGAGTCGGTCGGGCTGCCGCCTGCGGAACTCGGGATACTGATCGCGCACGCGCTGGTTGGAACCTTCCTCGGCATCC
TGCTCGCCTACGGGTTCGTCGGCCCGCTGGCCGGTCGTCTCGAGCAGAGAGTGCACGAATCGACCAAGATGCTGCAGTGC
GTGAAGGTGACGTTGCTCGCGAGCATCAACGGGTATGCGCCAGCGATCGCGGTCGAATTCGGCCGCAAGGTCCTGTTCTC
CACCGAGCGTCCTTCGTTCAGCGAACTCGAAGTGCACGTCAAGAGCGCGAAGTCGCGCTGA

Upstream 100 bases:

>100_bases
ACCGGTCGAATTCCTAGCCTGAGAGTCCTGCTTTCGCGCAGCTGAAAAAGGGCAGGGGCAGCGCGTTTGCCCGTCGAATC
ATTCGGAAGGAAGAGCCGGT

Downstream 100 bases:

>100_bases
CCGTTGGTACCCGATCGGTAGCGTCGAATGAGCGAGCAAAAAGCACCGATCATCGTCAAGCGGATCAAGAAGACCAGCGG
GGGCCACCACGGCGGCGCGT

Product: flagellar motor protein MotA

Products: NA

Alternate protein names: Chemotaxis protein MotA [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MLVIVGYVIVVLSVFGGFVLAGGHLAALFQPLELLMIGGGAIGAFLVGNNNKVIKATLKALPTVLKGSKYTRALYMDTLA
LLYELLTKIRKEGLMSVEADVDSPESSPLFSKYPAIMADHHVVEFLTDYLRLMVSGSMNAFEIENLMDNEIETHHHEGEV
PAHVIAKIGDGLPAFGIVAAVMGVVHTMESVGLPPAELGILIAHALVGTFLGILLAYGFVGPLAGRLEQRVHESTKMLQC
VKVTLLASINGYAPAIAVEFGRKVLFSTERPSFSELEVHVKSAKSR

Sequences:

>Translated_286_residues
MLVIVGYVIVVLSVFGGFVLAGGHLAALFQPLELLMIGGGAIGAFLVGNNNKVIKATLKALPTVLKGSKYTRALYMDTLA
LLYELLTKIRKEGLMSVEADVDSPESSPLFSKYPAIMADHHVVEFLTDYLRLMVSGSMNAFEIENLMDNEIETHHHEGEV
PAHVIAKIGDGLPAFGIVAAVMGVVHTMESVGLPPAELGILIAHALVGTFLGILLAYGFVGPLAGRLEQRVHESTKMLQC
VKVTLLASINGYAPAIAVEFGRKVLFSTERPSFSELEVHVKSAKSR
>Mature_286_residues
MLVIVGYVIVVLSVFGGFVLAGGHLAALFQPLELLMIGGGAIGAFLVGNNNKVIKATLKALPTVLKGSKYTRALYMDTLA
LLYELLTKIRKEGLMSVEADVDSPESSPLFSKYPAIMADHHVVEFLTDYLRLMVSGSMNAFEIENLMDNEIETHHHEGEV
PAHVIAKIGDGLPAFGIVAAVMGVVHTMESVGLPPAELGILIAHALVGTFLGILLAYGFVGPLAGRLEQRVHESTKMLQC
VKVTLLASINGYAPAIAVEFGRKVLFSTERPSFSELEVHVKSAKSR

Specific function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel. Overexpression of MotA, with or without MotB, restores motility in a yhjH disruption, (a c-di-GM

COG id: COG1291

COG function: function code N; Flagellar motor component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MotA family [H]

Homologues:

Organism=Escherichia coli, GI1788199, Length=285, Percent_Identity=61.4035087719298, Blast_Score=373, Evalue=1e-105,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000540
- InterPro:   IPR022522
- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 30707; Mature: 30707

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS01307 MOTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVIVGYVIVVLSVFGGFVLAGGHLAALFQPLELLMIGGGAIGAFLVGNNNKVIKATLKA
CEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHH
LPTVLKGSKYTRALYMDTLALLYELLTKIRKEGLMSVEADVDSPESSPLFSKYPAIMADH
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHCCHHHHHH
HVVEFLTDYLRLMVSGSMNAFEIENLMDNEIETHHHEGEVPAHVIAKIGDGLPAFGIVAA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHH
VMGVVHTMESVGLPPAELGILIAHALVGTFLGILLAYGFVGPLAGRLEQRVHESTKMLQC
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKVTLLASINGYAPAIAVEFGRKVLFSTERPSFSELEVHVKSAKSR
HHHHHHHHCCCCCCHHHHHHCCHHEECCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MLVIVGYVIVVLSVFGGFVLAGGHLAALFQPLELLMIGGGAIGAFLVGNNNKVIKATLKA
CEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHH
LPTVLKGSKYTRALYMDTLALLYELLTKIRKEGLMSVEADVDSPESSPLFSKYPAIMADH
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHCCHHHHHH
HVVEFLTDYLRLMVSGSMNAFEIENLMDNEIETHHHEGEVPAHVIAKIGDGLPAFGIVAA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHH
VMGVVHTMESVGLPPAELGILIAHALVGTFLGILLAYGFVGPLAGRLEQRVHESTKMLQC
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKVTLLASINGYAPAIAVEFGRKVLFSTERPSFSELEVHVKSAKSR
HHHHHHHHCCCCCCHHHHHHCCHHEECCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6090403; 9097040; 9278503; 3007435; 1719217; 7643400 [H]