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The map label for this gene is int [H]

Identifier: 74317233

GI number: 74317233

Start: 1270724

End: 1271704

Strand: Direct

Name: int [H]

Synonym: Tbd_1215

Alternate gene names: 74317233

Gene position: 1270724-1271704 (Clockwise)

Preceding gene: 74317232

Following gene: 74317234

Centisome position: 43.67

GC content: 64.63

Gene sequence:

>981_bases
ATGGAAGCTAAGGCTGTTTCTCAAGATTCGCCTAAATTGCTCGACCGGGTTCGGGCCGAGATCCGCGTGCGCCACTACAG
CCTGCGCACCGAGCAGTCCTACGTCGACTGGGCGCGGCGCTACATCCTCTTTCACCAGAAGCGGCACCCGGCGGAGATGG
GCGCGGCAGAGGTGCGCGAATTTCTTTCCCATCTGGCGGTCGAGCGGAATGTTTCGGCTTCGACGCAGAATCAGGCCAAG
TCGGCGCTGCTTTTCCTCTATCGCGAGGTGTTGAAGATCGAATTGCCGTGGCTCGACGAGGTTGTCGTCGCGAAGTCGGC
GAAGCGCCTGCCCGTGGTGCTGACGCAGGTCGAGGTGCGCGCGTTGCTGAACGCGATGTCGGGGACGATGGGCCTGGTGG
CGAGCCTGCTCTACGGCACTGGGATGCGGCTGCTCGAGGGGTTACGCCTGCGCGTCAAGGACGTGGAGTTCTCGCGGCGC
GAGATCATCGTGCGCGAGGGCAAAGGCAACAAGGATCGGGTGACGGTGCTGCCGGAAAACCTGATCCTGCCGCTCAAGGC
GCATCTCGAGAAGGTGCGGACGCTGCACGAGCGCGATCTCGAAGCGGGCTACGGCGCGGTCTATCTTCCCGATGCGCTGG
CGGCCAAGTATCCGAATGCGGCCCGCGCCTGGGGCTGGCAGTACGTCTTTCCGTCGCCGGTGCGTGCGGTCGATCCGCGC
TCGGGTGTCGAGCGCCGGCACCACGTCTACGAAACGAGCGTGCAGCGCGCGGTGCGCGAAGCGGCGAGGGCGGCCGGCCT
GCACAAGCCGGTGACGCCGCACGTTTTGCGCCATTCGTTCGCGACGCATCTGTTGCAGGCCGGTTACGATATCCGCACGG
TGCAGGAACTGCTCGGCCACAAGGACGTTTCGACGACGATGATTTACACCCACGTATTGAACAAGGGCGGGCGCGGCGTG
ACGAGCCCGCTCGACATGTGA

Upstream 100 bases:

>100_bases
AGACCGCCGCGCCGCCTAAATCAACCAGCCGGGCTTATTTCGCGCCGCTCAGTGACATCCACGCTTGAGCCCGCTTTTAG
ACACGCCTAAAATTCAGCGG

Downstream 100 bases:

>100_bases
TGGGCGACGAGGATTACATGCGCGCGGCGCTCGAACTCGCGGCCGAGGGCGCAGCGGCAGGCGAGGTGCCGGTCGGCGCG
CTTGTCGTGTGCGGCGGCGA

Product: integron integrase

Products: NA

Alternate protein names: E2 protein [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MEAKAVSQDSPKLLDRVRAEIRVRHYSLRTEQSYVDWARRYILFHQKRHPAEMGAAEVREFLSHLAVERNVSASTQNQAK
SALLFLYREVLKIELPWLDEVVVAKSAKRLPVVLTQVEVRALLNAMSGTMGLVASLLYGTGMRLLEGLRLRVKDVEFSRR
EIIVREGKGNKDRVTVLPENLILPLKAHLEKVRTLHERDLEAGYGAVYLPDALAAKYPNAARAWGWQYVFPSPVRAVDPR
SGVERRHHVYETSVQRAVREAARAAGLHKPVTPHVLRHSFATHLLQAGYDIRTVQELLGHKDVSTTMIYTHVLNKGGRGV
TSPLDM

Sequences:

>Translated_326_residues
MEAKAVSQDSPKLLDRVRAEIRVRHYSLRTEQSYVDWARRYILFHQKRHPAEMGAAEVREFLSHLAVERNVSASTQNQAK
SALLFLYREVLKIELPWLDEVVVAKSAKRLPVVLTQVEVRALLNAMSGTMGLVASLLYGTGMRLLEGLRLRVKDVEFSRR
EIIVREGKGNKDRVTVLPENLILPLKAHLEKVRTLHERDLEAGYGAVYLPDALAAKYPNAARAWGWQYVFPSPVRAVDPR
SGVERRHHVYETSVQRAVREAARAAGLHKPVTPHVLRHSFATHLLQAGYDIRTVQELLGHKDVSTTMIYTHVLNKGGRGV
TSPLDM
>Mature_326_residues
MEAKAVSQDSPKLLDRVRAEIRVRHYSLRTEQSYVDWARRYILFHQKRHPAEMGAAEVREFLSHLAVERNVSASTQNQAK
SALLFLYREVLKIELPWLDEVVVAKSAKRLPVVLTQVEVRALLNAMSGTMGLVASLLYGTGMRLLEGLRLRVKDVEFSRR
EIIVREGKGNKDRVTVLPENLILPLKAHLEKVRTLHERDLEAGYGAVYLPDALAAKYPNAARAWGWQYVFPSPVRAVDPR
SGVERRHHVYETSVQRAVREAARAAGLHKPVTPHVLRHSFATHLLQAGYDIRTVQELLGHKDVSTTMIYTHVLNKGGRGV
TSPLDM

Specific function: Putative integrase believed to be involved in the insertion of antibiotic resistance genes into plasmids and transposons [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=236, Percent_Identity=32.6271186440678, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790244, Length=177, Percent_Identity=32.7683615819209, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR011946
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 36895; Mature: 36895

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAKAVSQDSPKLLDRVRAEIRVRHYSLRTEQSYVDWARRYILFHQKRHPAEMGAAEVRE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHH
FLSHLAVERNVSASTQNQAKSALLFLYREVLKIELPWLDEVVVAKSAKRLPVVLTQVEVR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHH
ALLNAMSGTMGLVASLLYGTGMRLLEGLRLRVKDVEFSRREIIVREGKGNKDRVTVLPEN
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHEEEECCCCCCCEEEECCCC
LILPLKAHLEKVRTLHERDLEAGYGAVYLPDALAAKYPNAARAWGWQYVFPSPVRAVDPR
CEEHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHCCCCCHHHCCCEEECCCCCCCCCCC
SGVERRHHVYETSVQRAVREAARAAGLHKPVTPHVLRHSFATHLLQAGYDIRTVQELLGH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCC
KDVSTTMIYTHVLNKGGRGVTSPLDM
CCCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MEAKAVSQDSPKLLDRVRAEIRVRHYSLRTEQSYVDWARRYILFHQKRHPAEMGAAEVRE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHH
FLSHLAVERNVSASTQNQAKSALLFLYREVLKIELPWLDEVVVAKSAKRLPVVLTQVEVR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHH
ALLNAMSGTMGLVASLLYGTGMRLLEGLRLRVKDVEFSRREIIVREGKGNKDRVTVLPEN
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHEEEECCCCCCCEEEECCCC
LILPLKAHLEKVRTLHERDLEAGYGAVYLPDALAAKYPNAARAWGWQYVFPSPVRAVDPR
CEEHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHCCCCCHHHCCCEEECCCCCCCCCCC
SGVERRHHVYETSVQRAVREAARAAGLHKPVTPHVLRHSFATHLLQAGYDIRTVQELLGH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCC
KDVSTTMIYTHVLNKGGRGVTSPLDM
CCCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2821509; 2823258; 3054482; 8195081; 2188588 [H]