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The map label for this gene is glmM

Identifier: 74317153

GI number: 74317153

Start: 1190402

End: 1191778

Strand: Direct

Name: glmM

Synonym: Tbd_1135

Alternate gene names: 74317153

Gene position: 1190402-1191778 (Clockwise)

Preceding gene: 74317152

Following gene: 74317154

Centisome position: 40.91

GC content: 67.03

Gene sequence:

>1377_bases
ATGGGTCGTAAATACTTCGGTACCGACGGGGTCCGCGGCAAGGTCGGCGAAACGCCGATCACGCCCGAGTTCGTCATGCG
TCTCGGCTACGCGGCCGGCAAGGTGTTGGTGTCCGACCGCGGGAGCTTGCCCGCGAACGAGCATCCGACCGTGCTGATCG
GCAAGGACACGCGCATTTCCGGCTACATGCTCGAGGCGGCACTCGAAGCAGGCTTCACGGCGGCCGGCGTGAACGTTCTC
ATGACCGGTCCGATGCCGACCCCCGCCGTCGCCTACCTGACGCGTGCGCTACGCCTGCAGGCTGGCGTCGTGATCTCCGC
CTCGCACAATCCCTTCGAGGACAACGGCATCAAGTTCTTTTCGGCGAGCGGGCAGAAGCTCCCCGACAGCGTCGAGGAAG
CGATCGAGGCTGCGCTCGACCAGCCGCTCGCGACCGTCGCGGCGCGCCAGCTCGGGCGCGCGCGGCGAATCGAGGATGCG
GCCGCGCGCTACATCGAATTCTGCAAGAGCACCTTTCCCAACCGGCTCGACCTGCGCGGCATGCGCATCGTCGTCGACTG
CGCGCACGGCGCGACCTACCACGTCGCCCCCCATGTGCTGCACGAACTCGGCGCGGAAGTCGTGGCCATTGGCAACGAGC
CCAACGGCTTCAACATCAACGAAGCCTGCGGCGCGACGCATACGCCGGCGCTGGCCGACGCGGTTCGCGCGCATCACGCC
GACATCGGGATATCGCTCGACGGTGACGGCGACCGCCTGATGATGGCCGATGCCCACGGCCGGATCTACGACGGCGACCA
ACTCGTTTACGTGATCGCGCGCCACCGCCTCGAGACGGGCTACATGAAGGGCGGCGTGGTCGGCACGCTGATGACCAATC
TGGGTACCGAGCATGCGCTCGCGCGCATTCACGTGCCCTTCGAGCGCGCGAAGGTGGGCGATCGCTACGTGCTCAAGCGT
CTCCATGCCAACGGCTGGTTCCTCGGCGGTGAGACGTCGGGGCATATCCTCTGCCTCGACAAGCACACGACCGGTGACGG
CATCGTCTCGAGCCTGCAGGTGCTGCGCGCGCTGCGCGAGACCGGCAAAACGCTCGACGCCTTCACCGCCGACCTGGAAA
CCTATCCGCAGGTCATGATCAACGTGCCCGTCGTCAAGGGATTCAGGCTTAGTGACGCGGCGGCCGTCACCGTTGCCGTT
GCCGATGCGGAGTCTGCGTTGAATGGCAGCGGTCGCATCGTGCTGCGTGCGTCCGGTACCGAACCGCTGATCCGGGTGAT
GGTGGAGGGTCGCGACGGCGACCTCGTCCGCCGCACCGCCGAGATGATCGCGGACGCGGTACGAGCGGCCGCGGCGGCGA
GCGATATCGCGGTCTGA

Upstream 100 bases:

>100_bases
GCTGTGGCGCGGGGCGCGCGGATCGTTCGGGTACATAATGTCGCAGCCATGCGCGATGCGCTGGCGATCTGGAAAGCGGT
TGAGGGGAGGAGTCGTCAAG

Downstream 100 bases:

>100_bases
AATATATCTGTAATATTCGGCCGCTAGTATGGCGCGGTTGCCCGCGCGGCGACGTCCAACTACTACGGAGATTCTTCAGA
TGCTTACACTCAACGGACTG

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MGRKYFGTDGVRGKVGETPITPEFVMRLGYAAGKVLVSDRGSLPANEHPTVLIGKDTRISGYMLEAALEAGFTAAGVNVL
MTGPMPTPAVAYLTRALRLQAGVVISASHNPFEDNGIKFFSASGQKLPDSVEEAIEAALDQPLATVAARQLGRARRIEDA
AARYIEFCKSTFPNRLDLRGMRIVVDCAHGATYHVAPHVLHELGAEVVAIGNEPNGFNINEACGATHTPALADAVRAHHA
DIGISLDGDGDRLMMADAHGRIYDGDQLVYVIARHRLETGYMKGGVVGTLMTNLGTEHALARIHVPFERAKVGDRYVLKR
LHANGWFLGGETSGHILCLDKHTTGDGIVSSLQVLRALRETGKTLDAFTADLETYPQVMINVPVVKGFRLSDAAAVTVAV
ADAESALNGSGRIVLRASGTEPLIRVMVEGRDGDLVRRTAEMIADAVRAAAAASDIAV

Sequences:

>Translated_458_residues
MGRKYFGTDGVRGKVGETPITPEFVMRLGYAAGKVLVSDRGSLPANEHPTVLIGKDTRISGYMLEAALEAGFTAAGVNVL
MTGPMPTPAVAYLTRALRLQAGVVISASHNPFEDNGIKFFSASGQKLPDSVEEAIEAALDQPLATVAARQLGRARRIEDA
AARYIEFCKSTFPNRLDLRGMRIVVDCAHGATYHVAPHVLHELGAEVVAIGNEPNGFNINEACGATHTPALADAVRAHHA
DIGISLDGDGDRLMMADAHGRIYDGDQLVYVIARHRLETGYMKGGVVGTLMTNLGTEHALARIHVPFERAKVGDRYVLKR
LHANGWFLGGETSGHILCLDKHTTGDGIVSSLQVLRALRETGKTLDAFTADLETYPQVMINVPVVKGFRLSDAAAVTVAV
ADAESALNGSGRIVLRASGTEPLIRVMVEGRDGDLVRRTAEMIADAVRAAAAASDIAV
>Mature_457_residues
GRKYFGTDGVRGKVGETPITPEFVMRLGYAAGKVLVSDRGSLPANEHPTVLIGKDTRISGYMLEAALEAGFTAAGVNVLM
TGPMPTPAVAYLTRALRLQAGVVISASHNPFEDNGIKFFSASGQKLPDSVEEAIEAALDQPLATVAARQLGRARRIEDAA
ARYIEFCKSTFPNRLDLRGMRIVVDCAHGATYHVAPHVLHELGAEVVAIGNEPNGFNINEACGATHTPALADAVRAHHAD
IGISLDGDGDRLMMADAHGRIYDGDQLVYVIARHRLETGYMKGGVVGTLMTNLGTEHALARIHVPFERAKVGDRYVLKRL
HANGWFLGGETSGHILCLDKHTTGDGIVSSLQVLRALRETGKTLDAFTADLETYPQVMINVPVVKGFRLSDAAAVTVAVA
DAESALNGSGRIVLRASGTEPLIRVMVEGRDGDLVRRTAEMIADAVRAAAAASDIAV

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=448, Percent_Identity=58.2589285714286, Blast_Score=501, Evalue=1e-143,
Organism=Escherichia coli, GI1788361, Length=449, Percent_Identity=26.7260579064588, Blast_Score=104, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_THIDA (Q3SJR2)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_314893.1
- HSSP:   O58651
- ProteinModelPortal:   Q3SJR2
- SMR:   Q3SJR2
- STRING:   Q3SJR2
- GeneID:   3673206
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_1135
- NMPDR:   fig|292415.3.peg.1134
- eggNOG:   COG1109
- HOGENOM:   HBG644964
- OMA:   EEAGINS
- PhylomeDB:   Q3SJR2
- BioCyc:   TDEN292415:TBD_1135-MONOMER
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 48744; Mature: 48613

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 108-108

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRKYFGTDGVRGKVGETPITPEFVMRLGYAAGKVLVSDRGSLPANEHPTVLIGKDTRIS
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEECCCCCC
GYMLEAALEAGFTAAGVNVLMTGPMPTPAVAYLTRALRLQAGVVISASHNPFEDNGIKFF
HHHHHHHHHCCCEECCCEEEEECCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEE
SASGQKLPDSVEEAIEAALDQPLATVAARQLGRARRIEDAAARYIEFCKSTFPNRLDLRG
ECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
MRIVVDCAHGATYHVAPHVLHELGAEVVAIGNEPNGFNINEACGATHTPALADAVRAHHA
EEEEEEECCCCEEEHHHHHHHHCCCEEEEECCCCCCCCCHHHCCCCCCHHHHHHHHHHHC
DIGISLDGDGDRLMMADAHGRIYDGDQLVYVIARHRLETGYMKGGVVGTLMTNLGTEHAL
CEEEEECCCCCEEEEEECCCCEECCCCEEEEEEHHHHHCCCCCCCHHHHHHHHCCCCCCE
ARIHVPFERAKVGDRYVLKRLHANGWFLGGETSGHILCLDKHTTGDGIVSSLQVLRALRE
EEEECCHHHHHCCHHHHHHHHCCCCEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
TGKTLDAFTADLETYPQVMINVPVVKGFRLSDAAAVTVAVADAESALNGSGRIVLRASGT
CCCCHHHHHHHHHHCCEEEEECCEECCEEECCCCEEEEEEECHHHHCCCCCEEEEEECCC
EPLIRVMVEGRDGDLVRRTAEMIADAVRAAAAASDIAV
CCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GRKYFGTDGVRGKVGETPITPEFVMRLGYAAGKVLVSDRGSLPANEHPTVLIGKDTRIS
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEECCCCCC
GYMLEAALEAGFTAAGVNVLMTGPMPTPAVAYLTRALRLQAGVVISASHNPFEDNGIKFF
HHHHHHHHHCCCEECCCEEEEECCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEE
SASGQKLPDSVEEAIEAALDQPLATVAARQLGRARRIEDAAARYIEFCKSTFPNRLDLRG
ECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
MRIVVDCAHGATYHVAPHVLHELGAEVVAIGNEPNGFNINEACGATHTPALADAVRAHHA
EEEEEEECCCCEEEHHHHHHHHCCCEEEEECCCCCCCCCHHHCCCCCCHHHHHHHHHHHC
DIGISLDGDGDRLMMADAHGRIYDGDQLVYVIARHRLETGYMKGGVVGTLMTNLGTEHAL
CEEEEECCCCCEEEEEECCCCEECCCCEEEEEEHHHHHCCCCCCCHHHHHHHHCCCCCCE
ARIHVPFERAKVGDRYVLKRLHANGWFLGGETSGHILCLDKHTTGDGIVSSLQVLRALRE
EEEECCHHHHHCCHHHHHHHHCCCCEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
TGKTLDAFTADLETYPQVMINVPVVKGFRLSDAAAVTVAVADAESALNGSGRIVLRASGT
CCCCHHHHHHHHHHCCEEEEECCEECCEEECCCCEEEEEEECHHHHCCCCCEEEEEECCC
EPLIRVMVEGRDGDLVRRTAEMIADAVRAAAAASDIAV
CCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA