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The map label for this gene is dapB

Identifier: 74317143

GI number: 74317143

Start: 1179970

End: 1180773

Strand: Direct

Name: dapB

Synonym: Tbd_1125

Alternate gene names: 74317143

Gene position: 1179970-1180773 (Clockwise)

Preceding gene: 74317142

Following gene: 74317144

Centisome position: 40.55

GC content: 71.52

Gene sequence:

>804_bases
GTGAGCGTGCGCGTCGCCATCGCAGGGGTGTCGGGTCGCATGGGCCGTGCCTTGCTCGAAGCCGTGGCCGCGGACGACGG
CTGCGCGCTCTACGCGGCGCTGGACCGGCCGGGCAGTTCGCTCGTGGGCCAGGACGCCGGCGCGGCCTGGGGCGCGGCGA
ACGGGGTGACGGTGACCGATCAGGCGCAGGCCGCGCTGAAGGGTGCGCAGGTGCTCGTCGATTTCACGCGCCCCGAGGCG
ACGTTCGGCTATCTCGAGGCCTGCGCGCTTGACGGCGTTCCCGTCGTGATCGGCACGACCGGGTTCGATGAGGCCGGCAG
GGCGCGGATCGCCGCCGCGGCCGAGCGTGTCCCGGTCGTCTTCGCACCCAACATGAGCGTCGGCGTCAATCTGTTGATGA
AACTCGCCGAAGTGGCGGCCGAGGTCCTGCAGGACGGATACGACATCGAAATCATCGAGGCGCACCACCGCCACAAGGTC
GACGCGCCGTCGGGCACCGCGCTCGGACTCGGGCAGGCGGTCGCGCGCGCCAGCGGTCGCGACCTCGAGGCCTGCGCCGT
CTATGGGCGCGAAGGGGTGACCGGTGAGCGTGATCCGCGCACGATCGGCTTTGCCACCGTGCGCGGGGGCGACATCGTCG
GCGACCACACCCTGCTCTTTGCCGGCGTCGGCGAGCGGGTCGAACTCACCCACAAGGCCAGCAGCCGCGCGACCTTCGCC
CAGGGCGCTCTGCGCGCCGCGAAGTGGGTGCAGGGCCGTGCGCCCGGTCTCTACGACATGCGCGACGTCCTTGGCCTGAA
ATAG

Upstream 100 bases:

>100_bases
ACCGCGACGCCGTGCTCAAGCGGCTGCTCATGGTCGAACGCGATGGTCGCTGGCTGATCGTCGAAGAGAAAGTGCTGCAG
ACCCTCGAGCGAGGCCGCCC

Downstream 100 bases:

>100_bases
TCAAACGTCTGAACAGGAAAACAGCATGAATGCCGTCAAGGTCTACAGTACGGGCACCTGCCCGATTTGCGTCAAGGCCA
AGGCCTTTCTCGACAAGCGC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MSVRVAIAGVSGRMGRALLEAVAADDGCALYAALDRPGSSLVGQDAGAAWGAANGVTVTDQAQAALKGAQVLVDFTRPEA
TFGYLEACALDGVPVVIGTTGFDEAGRARIAAAAERVPVVFAPNMSVGVNLLMKLAEVAAEVLQDGYDIEIIEAHHRHKV
DAPSGTALGLGQAVARASGRDLEACAVYGREGVTGERDPRTIGFATVRGGDIVGDHTLLFAGVGERVELTHKASSRATFA
QGALRAAKWVQGRAPGLYDMRDVLGLK

Sequences:

>Translated_267_residues
MSVRVAIAGVSGRMGRALLEAVAADDGCALYAALDRPGSSLVGQDAGAAWGAANGVTVTDQAQAALKGAQVLVDFTRPEA
TFGYLEACALDGVPVVIGTTGFDEAGRARIAAAAERVPVVFAPNMSVGVNLLMKLAEVAAEVLQDGYDIEIIEAHHRHKV
DAPSGTALGLGQAVARASGRDLEACAVYGREGVTGERDPRTIGFATVRGGDIVGDHTLLFAGVGERVELTHKASSRATFA
QGALRAAKWVQGRAPGLYDMRDVLGLK
>Mature_266_residues
SVRVAIAGVSGRMGRALLEAVAADDGCALYAALDRPGSSLVGQDAGAAWGAANGVTVTDQAQAALKGAQVLVDFTRPEAT
FGYLEACALDGVPVVIGTTGFDEAGRARIAAAAERVPVVFAPNMSVGVNLLMKLAEVAAEVLQDGYDIEIIEAHHRHKVD
APSGTALGLGQAVARASGRDLEACAVYGREGVTGERDPRTIGFATVRGGDIVGDHTLLFAGVGERVELTHKASSRATFAQ
GALRAAKWVQGRAPGLYDMRDVLGLK

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=267, Percent_Identity=60.2996254681648, Blast_Score=303, Evalue=1e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_THIDA (Q3SJS2)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_314883.1
- ProteinModelPortal:   Q3SJS2
- SMR:   Q3SJS2
- STRING:   Q3SJS2
- GeneID:   3673196
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_1125
- NMPDR:   fig|292415.3.peg.1124
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   YNNENIE
- PhylomeDB:   Q3SJS2
- BioCyc:   TDEN292415:TBD_1125-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 27522; Mature: 27390

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVRVAIAGVSGRMGRALLEAVAADDGCALYAALDRPGSSLVGQDAGAAWGAANGVTVTD
CCEEEEEEECCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEECH
QAQAALKGAQVLVDFTRPEATFGYLEACALDGVPVVIGTTGFDEAGRARIAAAAERVPVV
HHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHCCCEE
FAPNMSVGVNLLMKLAEVAAEVLQDGYDIEIIEAHHRHKVDAPSGTALGLGQAVARASGR
ECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCC
DLEACAVYGREGVTGERDPRTIGFATVRGGDIVGDHTLLFAGVGERVELTHKASSRATFA
CCHHHEEECCCCCCCCCCCCEEEEEEECCCCEECCCEEEEECCCCEEEEEECCCCCHHHH
QGALRAAKWVQGRAPGLYDMRDVLGLK
HHHHHHHHHHCCCCCCCCHHHHHHCCC
>Mature Secondary Structure 
SVRVAIAGVSGRMGRALLEAVAADDGCALYAALDRPGSSLVGQDAGAAWGAANGVTVTD
CEEEEEEECCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEECH
QAQAALKGAQVLVDFTRPEATFGYLEACALDGVPVVIGTTGFDEAGRARIAAAAERVPVV
HHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHCCCEE
FAPNMSVGVNLLMKLAEVAAEVLQDGYDIEIIEAHHRHKVDAPSGTALGLGQAVARASGR
ECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCC
DLEACAVYGREGVTGERDPRTIGFATVRGGDIVGDHTLLFAGVGERVELTHKASSRATFA
CCHHHEEECCCCCCCCCCCCEEEEEEECCCCEECCCEEEEECCCCEEEEEECCCCCHHHH
QGALRAAKWVQGRAPGLYDMRDVLGLK
HHHHHHHHHHCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA