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The map label for this gene is infC [H]

Identifier: 74317026

GI number: 74317026

Start: 1077920

End: 1078387

Strand: Direct

Name: infC [H]

Synonym: Tbd_1008

Alternate gene names: 74317026

Gene position: 1077920-1078387 (Clockwise)

Preceding gene: 74317025

Following gene: 74317027

Centisome position: 37.04

GC content: 57.69

Gene sequence:

>468_bases
GTGCGTTTGGTCGGCGCGGAAGGGGAGCAGCTTGGCATCGTAAAGATCTACGAGGCGCTGCGGCAGGCTGAGGAAGCTGA
CCTGGACCTGGTAGAGATCGCGCCCACGGCGCAGCCGCCCGTGGCCAAGATCATGGACTACGGCAAGTTCAAGTATCAGG
AAAGCAAGAAGCAGCACGAAGCCAAGCTCAAGCAGAAGCAGGTCCAGATCAAGGAAATCAAGTTCCGTCCGGGCACGGAC
GAGGGCGATTACCAGATCAAGCTGCGGAACCTGATCAAGTTTCTTGAAGAAGGCGATAAGACGAAGATTACGCTGCGTTT
CCGGGGCCGCGAAATGGCCCACCAGGAAATCGGCATGGCGCAGTTGAGACGGGTGTCGACGGATCTGGCCGAATTGGCCG
TCGTCGAGCAGTTCCCGAAGATGGAAGGTCGTCAGCTCGTGATGATGCTGGCGCCGAAGAAGAAATAA

Upstream 100 bases:

>100_bases
GCCATTTGCCTCGGCATGGCGCCGGGTTTTATTTGGAGAACGACTCATCGCGACAGAAAAGAAGCAGACACGCATCAACG
GCGAGATTACGGCGCCTGAA

Downstream 100 bases:

>100_bases
GGTTTGTGAGGCTGGCGTTCCTCGGCTCGTCAGGGCCAAAACGCCGACAATACGTGCATCCGGGTAGGTGAAGCATTCCG
CGTCGCGGGGTCACCTGGCT

Product: translation initiation factor 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MRLVGAEGEQLGIVKIYEALRQAEEADLDLVEIAPTAQPPVAKIMDYGKFKYQESKKQHEAKLKQKQVQIKEIKFRPGTD
EGDYQIKLRNLIKFLEEGDKTKITLRFRGREMAHQEIGMAQLRRVSTDLAELAVVEQFPKMEGRQLVMMLAPKKK

Sequences:

>Translated_155_residues
MRLVGAEGEQLGIVKIYEALRQAEEADLDLVEIAPTAQPPVAKIMDYGKFKYQESKKQHEAKLKQKQVQIKEIKFRPGTD
EGDYQIKLRNLIKFLEEGDKTKITLRFRGREMAHQEIGMAQLRRVSTDLAELAVVEQFPKMEGRQLVMMLAPKKK
>Mature_155_residues
MRLVGAEGEQLGIVKIYEALRQAEEADLDLVEIAPTAQPPVAKIMDYGKFKYQESKKQHEAKLKQKQVQIKEIKFRPGTD
EGDYQIKLRNLIKFLEEGDKTKITLRFRGREMAHQEIGMAQLRRVSTDLAELAVVEQFPKMEGRQLVMMLAPKKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=156, Percent_Identity=72.4358974358974, Blast_Score=214, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 17855; Mature: 17855

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLVGAEGEQLGIVKIYEALRQAEEADLDLVEIAPTAQPPVAKIMDYGKFKYQESKKQHE
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHCCCHHHHHHHHHHH
AKLKQKQVQIKEIKFRPGTDEGDYQIKLRNLIKFLEEGDKTKITLRFRGREMAHQEIGMA
HHHHHHHHHHHHEEECCCCCCCCEEEHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHH
QLRRVSTDLAELAVVEQFPKMEGRQLVMMLAPKKK
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCC
>Mature Secondary Structure
MRLVGAEGEQLGIVKIYEALRQAEEADLDLVEIAPTAQPPVAKIMDYGKFKYQESKKQHE
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHCCCHHHHHHHHHHH
AKLKQKQVQIKEIKFRPGTDEGDYQIKLRNLIKFLEEGDKTKITLRFRGREMAHQEIGMA
HHHHHHHHHHHHEEECCCCCCCCEEEHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHH
QLRRVSTDLAELAVVEQFPKMEGRQLVMMLAPKKK
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]