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The map label for this gene is nisX1 [H]

Identifier: 74316946

GI number: 74316946

Start: 984317

End: 985036

Strand: Direct

Name: nisX1 [H]

Synonym: Tbd_0928

Alternate gene names: 74316946

Gene position: 984317-985036 (Clockwise)

Preceding gene: 74316938

Following gene: 74316947

Centisome position: 33.83

GC content: 57.36

Gene sequence:

>720_bases
TTGCTCGGCCTGATCCGAGCGTCGTTCGAAGAGAGCCAAGGTATATACGGCGCGCCACGCGTCTTTCTCGATCTTCGAGA
GGCCGGTGAAACGTGTAGCAAACATCGTGTTGCACGGCTGATGAAAGAGAACGGTATACGAGCGAAAGGCGGTTACCGGA
CCCGACGTTACGTCGCAGGTGGCAAGACAGCGGAGCTGATCCCGAACCTCGTCAAGCGCAATTTTGACGTTTCGCAGCCC
AACCGCGTCTGGGTCACTGACATCACGTATGTCCGGACCTGGCAGGGCTGGCTCTACTTGGCCGTCGTATTGGACTTGTT
CTCCCGCAAAGTGATCGGCTGGGCCACACGCCAATCCATCCATCGAGCTCTCGTCTTAGATGCCCTCTTGATCGCCGTGC
GTCAGCGCGCTCCAGACGGCACGATCGTGCACTCCGATCAGGGCTCGCAATACGGCAGCGACGACTGGCGCCGCTTCTGC
CGGTCGAACGGTCTATGGCCCAGCATGAGTCGACGAGGTAACTGCTGGGACAACGCGGTAGCCGAGTCCTTCTTCTCGAG
CCTGAAGAAAGAGCGCATCAAGAAACGCATCTACAACACGCGCCAGCAAGCGACGGAAGATATCGCGGATTACATCGATG
ACTTCTACAATCGAACGCGAAGACACAAACATTTATCGGGCGTGAGCCCCGAACAATTTGAAGCCGCAGCAACCCGTTAA

Upstream 100 bases:

>100_bases
CTTGATCGGCTGCGGCGGATAGCTCAGCAACCACACCCTCAGGACCGCCACCCTTAAGGCGGCGAAGCTCACGCCACACG
CTAACAGGTGGCCCAGGCGC

Downstream 100 bases:

>100_bases
CCGCCCGGTGTCCACAGAATCCTGGGAACTCCATCCAGCTGTGATTTTCCCTCGATCCGTCCATATAACCCTTCGACACC
CTAAGGTCGAGGGCTGGAAT

Product: transposase InsF for insertion sequence IS3A/B/C/D/E/fA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MLGLIRASFEESQGIYGAPRVFLDLREAGETCSKHRVARLMKENGIRAKGGYRTRRYVAGGKTAELIPNLVKRNFDVSQP
NRVWVTDITYVRTWQGWLYLAVVLDLFSRKVIGWATRQSIHRALVLDALLIAVRQRAPDGTIVHSDQGSQYGSDDWRRFC
RSNGLWPSMSRRGNCWDNAVAESFFSSLKKERIKKRIYNTRQQATEDIADYIDDFYNRTRRHKHLSGVSPEQFEAAATR

Sequences:

>Translated_239_residues
MLGLIRASFEESQGIYGAPRVFLDLREAGETCSKHRVARLMKENGIRAKGGYRTRRYVAGGKTAELIPNLVKRNFDVSQP
NRVWVTDITYVRTWQGWLYLAVVLDLFSRKVIGWATRQSIHRALVLDALLIAVRQRAPDGTIVHSDQGSQYGSDDWRRFC
RSNGLWPSMSRRGNCWDNAVAESFFSSLKKERIKKRIYNTRQQATEDIADYIDDFYNRTRRHKHLSGVSPEQFEAAATR
>Mature_239_residues
MLGLIRASFEESQGIYGAPRVFLDLREAGETCSKHRVARLMKENGIRAKGGYRTRRYVAGGKTAELIPNLVKRNFDVSQP
NRVWVTDITYVRTWQGWLYLAVVLDLFSRKVIGWATRQSIHRALVLDALLIAVRQRAPDGTIVHSDQGSQYGSDDWRRFC
RSNGLWPSMSRRGNCWDNAVAESFFSSLKKERIKKRIYNTRQQATEDIADYIDDFYNRTRRHKHLSGVSPEQFEAAATR

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=206, Percent_Identity=34.4660194174757, Blast_Score=119, Evalue=2e-27,
Organism=Escherichia coli, GI1788405, Length=235, Percent_Identity=42.1276595744681, Blast_Score=172, Evalue=1e-44,
Organism=Escherichia coli, GI1787263, Length=235, Percent_Identity=42.1276595744681, Blast_Score=172, Evalue=1e-44,
Organism=Escherichia coli, GI1786753, Length=235, Percent_Identity=42.1276595744681, Blast_Score=172, Evalue=1e-44,
Organism=Escherichia coli, GI1786570, Length=235, Percent_Identity=42.1276595744681, Blast_Score=172, Evalue=1e-44,
Organism=Escherichia coli, GI1786490, Length=235, Percent_Identity=42.1276595744681, Blast_Score=172, Evalue=1e-44,
Organism=Escherichia coli, GI1789981, Length=231, Percent_Identity=32.4675324675325, Blast_Score=126, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 27545; Mature: 27545

Theoretical pI: Translated: 10.56; Mature: 10.56

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGLIRASFEESQGIYGAPRVFLDLREAGETCSKHRVARLMKENGIRAKGGYRTRRYVAG
CCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCC
GKTAELIPNLVKRNFDVSQPNRVWVTDITYVRTWQGWLYLAVVLDLFSRKVIGWATRQSI
CCHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HRALVLDALLIAVRQRAPDGTIVHSDQGSQYGSDDWRRFCRSNGLWPSMSRRGNCWDNAV
HHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHH
AESFFSSLKKERIKKRIYNTRQQATEDIADYIDDFYNRTRRHKHLSGVSPEQFEAAATR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
>Mature Secondary Structure
MLGLIRASFEESQGIYGAPRVFLDLREAGETCSKHRVARLMKENGIRAKGGYRTRRYVAG
CCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCC
GKTAELIPNLVKRNFDVSQPNRVWVTDITYVRTWQGWLYLAVVLDLFSRKVIGWATRQSI
CCHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HRALVLDALLIAVRQRAPDGTIVHSDQGSQYGSDDWRRFCRSNGLWPSMSRRGNCWDNAV
HHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHH
AESFFSSLKKERIKKRIYNTRQQATEDIADYIDDFYNRTRRHKHLSGVSPEQFEAAATR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1482189; 11337471; 1482192 [H]