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The map label for this gene is cusB [H]

Identifier: 74316919

GI number: 74316919

Start: 952936

End: 954249

Strand: Direct

Name: cusB [H]

Synonym: Tbd_0901

Alternate gene names: 74316919

Gene position: 952936-954249 (Clockwise)

Preceding gene: 74316918

Following gene: 74316920

Centisome position: 32.75

GC content: 69.79

Gene sequence:

>1314_bases
ATGCGCATTGAGCGATTCCGTCTTCGCCAAGCGGCGTCGGCCTGGCGGCGGGGTGCCGCGCTGCTGAGCTTCGCCGCGGG
CAGCGTGTTCGCCCCGTCCGTGCTCGCGCACAGCGACCCGCACGTGTTCGGCCAGTCGGCGCCGGCTAAAGCTGCGCCGG
GTAAATCGGCCCCCGCACCCGCCGCGCCGGACAAGGCCGGTACGGCGCCGAAAGCCGGGAAGGCTGCGAACGCCGGGGCG
GCGGCGAAACCCGGCACGGAACCCACGGTTCAGGCCGGGGAGGCAGTGAATCTGCCTGCCGACGCCAAGGCCACGCGGGG
CCTCTTCACGCTCGCGACGGCGCGTGGCGGCGCGCAGGCGGGCGGGATCAAGACCTACGGTCTGGTCGTGCCGAACAGCC
AGGCGATGGTCGACGTGAACATCGCCGTCAGCGGCCAGGTCGTCGACGTGTTCGTGCGCGTCGGCGACAGTGTGCGCAAA
GGCGAGCCGATCGTCGCCATCTTCAATCCCGAATTCATCACGACGCAACGCGGCTATCTCGAATTCCTCAAGAACGAGGA
GAAGCTGCAGGTGCTGCGTGAAGAGGGCCGGCTGCCGAACTATCTCAAGGACGCCAAGGAAAACCTGCGCTGGTGGGGCA
TGACGGACAAGGAGATCGCCGCCCTCATCGAGCACGGCAGGGTCGTCGAGCACATCCGGCTCGACGCGCCGACCGACGGT
TTCATCACCGAACTGCTGGTGCAGCCGGGTTCGCTGGTCAACGCCGGCGACCGCACGATGAAGCAGTTCGTCGTCGTCGG
CCGGGCCGTCGCGCGCATGGTGTCGGCCGATGCGCCGCACTGGCTCGAAGGCTACGTCTACCCCGACCAGAGGGCGCTCG
TGCAGCCCGGCGTGCCGGTGCGCGTCAGCTTGCCCGACGGCCGCGAGCTCGAGCGGCGGGTGACCCAGGTCATGCCGGTC
GTCGACCCGGCGACGCAGCGTGCGCGCTTTCTCGTCGACCTTGGCAAGGCGGGGGCGGCGCTGACCGTCGGCCAGACTGT
CGACCTGAGCCTGCTGCTCGACAAGCCGACCGGGGTCTGGGTGCCGCGTGGCGCCGTGCTCGGGCAGGGGCTCGCCCCGG
TCGTGTTCGTCCAGCGCGCGCCCGGACGGTACCTGCGGCGGACGGTGCAGGTCGTCGACGAAACCGCCACGCTGCTGCGC
GTGAACGGCGTGGCCGCAGGGGAAAAGCTGGTGGTCGCCGGAAAAATGATGCTCGAAGGCCTCTATCGCATTTCGGCGCG
CCCCGCCGCGGCCGCCGACCATCATCATCACTGA

Upstream 100 bases:

>100_bases
CAGCGCCAGCGCGTGCGGCTCAAGCTCGCCGGCAACCCGCCTAAAGGGGTCGCGCTGCCCGCTGGTCTGCAGGCGAGCGT
CAGCCTCGAGGAACCCGACC

Downstream 100 bases:

>100_bases
CGCAGCGGATCGACACATGTTTGATTGGGTAATCGGATGGTCCTTGCGGAACCGCGTCACGGTGGTTCTGCTGTATCTCA
TTCTGGCCGGCGCGGCCATC

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MRIERFRLRQAASAWRRGAALLSFAAGSVFAPSVLAHSDPHVFGQSAPAKAAPGKSAPAPAAPDKAGTAPKAGKAANAGA
AAKPGTEPTVQAGEAVNLPADAKATRGLFTLATARGGAQAGGIKTYGLVVPNSQAMVDVNIAVSGQVVDVFVRVGDSVRK
GEPIVAIFNPEFITTQRGYLEFLKNEEKLQVLREEGRLPNYLKDAKENLRWWGMTDKEIAALIEHGRVVEHIRLDAPTDG
FITELLVQPGSLVNAGDRTMKQFVVVGRAVARMVSADAPHWLEGYVYPDQRALVQPGVPVRVSLPDGRELERRVTQVMPV
VDPATQRARFLVDLGKAGAALTVGQTVDLSLLLDKPTGVWVPRGAVLGQGLAPVVFVQRAPGRYLRRTVQVVDETATLLR
VNGVAAGEKLVVAGKMMLEGLYRISARPAAAADHHHH

Sequences:

>Translated_437_residues
MRIERFRLRQAASAWRRGAALLSFAAGSVFAPSVLAHSDPHVFGQSAPAKAAPGKSAPAPAAPDKAGTAPKAGKAANAGA
AAKPGTEPTVQAGEAVNLPADAKATRGLFTLATARGGAQAGGIKTYGLVVPNSQAMVDVNIAVSGQVVDVFVRVGDSVRK
GEPIVAIFNPEFITTQRGYLEFLKNEEKLQVLREEGRLPNYLKDAKENLRWWGMTDKEIAALIEHGRVVEHIRLDAPTDG
FITELLVQPGSLVNAGDRTMKQFVVVGRAVARMVSADAPHWLEGYVYPDQRALVQPGVPVRVSLPDGRELERRVTQVMPV
VDPATQRARFLVDLGKAGAALTVGQTVDLSLLLDKPTGVWVPRGAVLGQGLAPVVFVQRAPGRYLRRTVQVVDETATLLR
VNGVAAGEKLVVAGKMMLEGLYRISARPAAAADHHHH
>Mature_437_residues
MRIERFRLRQAASAWRRGAALLSFAAGSVFAPSVLAHSDPHVFGQSAPAKAAPGKSAPAPAAPDKAGTAPKAGKAANAGA
AAKPGTEPTVQAGEAVNLPADAKATRGLFTLATARGGAQAGGIKTYGLVVPNSQAMVDVNIAVSGQVVDVFVRVGDSVRK
GEPIVAIFNPEFITTQRGYLEFLKNEEKLQVLREEGRLPNYLKDAKENLRWWGMTDKEIAALIEHGRVVEHIRLDAPTDG
FITELLVQPGSLVNAGDRTMKQFVVVGRAVARMVSADAPHWLEGYVYPDQRALVQPGVPVRVSLPDGRELERRVTQVMPV
VDPATQRARFLVDLGKAGAALTVGQTVDLSLLLDKPTGVWVPRGAVLGQGLAPVVFVQRAPGRYLRRTVQVVDETATLLR
VNGVAAGEKLVVAGKMMLEGLYRISARPAAAADHHHH

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=343, Percent_Identity=24.7813411078717, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 46513; Mature: 46513

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIERFRLRQAASAWRRGAALLSFAAGSVFAPSVLAHSDPHVFGQSAPAKAAPGKSAPAP
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCC
AAPDKAGTAPKAGKAANAGAAAKPGTEPTVQAGEAVNLPADAKATRGLFTLATARGGAQA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCHHHCCEEEEEECCCCCCC
GGIKTYGLVVPNSQAMVDVNIAVSGQVVDVFVRVGDSVRKGEPIVAIFNPEFITTQRGYL
CCEEEEEEEECCCCEEEEEEEEECCCEEEHHHHHCCCCCCCCCEEEEECCCEEECCHHHH
EFLKNEEKLQVLREEGRLPNYLKDAKENLRWWGMTDKEIAALIEHGRVVEHIRLDAPTDG
HHHCCHHHHHHHHHCCCCCHHHHHHHHCCEECCCCHHHHHHHHHCCCEEEEEEECCCCCH
FITELLVQPGSLVNAGDRTMKQFVVVGRAVARMVSADAPHWLEGYVYPDQRALVQPGVPV
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHCCEECCCCCHHCCCCCCE
RVSLPDGRELERRVTQVMPVVDPATQRARFLVDLGKAGAALTVGQTVDLSLLLDKPTGVW
EEECCCCHHHHHHHHHHHCCCCCHHHHHHHHEEECCCCCEEEECCEEEEEEEEECCCCCE
VPRGAVLGQGLAPVVFVQRAPGRYLRRTVQVVDETATLLRVNGVAAGEKLVVAGKMMLEG
ECCHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHEEEEEECCCCCCCEEEEHHHHHHHH
LYRISARPAAAADHHHH
HHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MRIERFRLRQAASAWRRGAALLSFAAGSVFAPSVLAHSDPHVFGQSAPAKAAPGKSAPAP
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCC
AAPDKAGTAPKAGKAANAGAAAKPGTEPTVQAGEAVNLPADAKATRGLFTLATARGGAQA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCHHHCCEEEEEECCCCCCC
GGIKTYGLVVPNSQAMVDVNIAVSGQVVDVFVRVGDSVRKGEPIVAIFNPEFITTQRGYL
CCEEEEEEEECCCCEEEEEEEEECCCEEEHHHHHCCCCCCCCCEEEEECCCEEECCHHHH
EFLKNEEKLQVLREEGRLPNYLKDAKENLRWWGMTDKEIAALIEHGRVVEHIRLDAPTDG
HHHCCHHHHHHHHHCCCCCHHHHHHHHCCEECCCCHHHHHHHHHCCCEEEEEEECCCCCH
FITELLVQPGSLVNAGDRTMKQFVVVGRAVARMVSADAPHWLEGYVYPDQRALVQPGVPV
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHCCEECCCCCHHCCCCCCE
RVSLPDGRELERRVTQVMPVVDPATQRARFLVDLGKAGAALTVGQTVDLSLLLDKPTGVW
EEECCCCHHHHHHHHHHHCCCCCHHHHHHHHEEECCCCCEEEECCEEEEEEEEECCCCCE
VPRGAVLGQGLAPVVFVQRAPGRYLRRTVQVVDETATLLRVNGVAAGEKLVVAGKMMLEG
ECCHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHEEEEEECCCCCCCEEEEHHHHHHHH
LYRISARPAAAADHHHH
HHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]