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The map label for this gene is acyP

Identifier: 74316877

GI number: 74316877

Start: 910414

End: 910683

Strand: Reverse

Name: acyP

Synonym: Tbd_0859

Alternate gene names: 74316877

Gene position: 910683-910414 (Counterclockwise)

Preceding gene: 74316878

Following gene: 74316873

Centisome position: 31.3

GC content: 68.52

Gene sequence:

>270_bases
GTGAAGACGCTGCACCTGCAGATCGAGGGCCGCGTCCAGGGGGTATGGTTCCGCGAATCGATGCGGCGCGAGGCCGAGCG
CCTCGGCGTCGACGGCTGGGTAAGGAACCGGCCGGACGGCTCAGTGGAAGCAGTCGTCCAGGGGACCGACGAAGCCGTCG
CGGCGCTTGTCGCCTGGGCGAAAATGGGGCCGCCGCTCGCGCACGTCGAACGCGTCGACCTCAGCGAGACGGAAGGCGAA
TACAGCGGCTTCGAGAAGCGCAGCGACTAG

Upstream 100 bases:

>100_bases
GCCGCCTCCAACCCCGACGGGCATAAAGACGACGTGCCCGGCCTCTTCATCCTCTCGCCCGACAGCGGCGCCGAGCCGGG
CATGAAGGTCAAGTAAGCCG

Downstream 100 bases:

>100_bases
CCACCGCCACCAAAAAAGGACAAAAAAATGCCCAGCTCGCGAGAGCCGGGCAGAGTATCCACCAAAGGAGGAGGATTGGA
GGAGACAACACTCAGTGACC

Product: putative acylphosphatase

Products: NA

Alternate protein names: Acylphosphate phosphohydrolase

Number of amino acids: Translated: 89; Mature: 89

Protein sequence:

>89_residues
MKTLHLQIEGRVQGVWFRESMRREAERLGVDGWVRNRPDGSVEAVVQGTDEAVAALVAWAKMGPPLAHVERVDLSETEGE
YSGFEKRSD

Sequences:

>Translated_89_residues
MKTLHLQIEGRVQGVWFRESMRREAERLGVDGWVRNRPDGSVEAVVQGTDEAVAALVAWAKMGPPLAHVERVDLSETEGE
YSGFEKRSD
>Mature_89_residues
MKTLHLQIEGRVQGVWFRESMRREAERLGVDGWVRNRPDGSVEAVVQGTDEAVAALVAWAKMGPPLAHVERVDLSETEGE
YSGFEKRSD

Specific function: Unknown

COG id: COG1254

COG function: function code C; Acylphosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acylphosphatase-like domain

Homologues:

Organism=Homo sapiens, GI20149322, Length=92, Percent_Identity=36.9565217391304, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787203, Length=84, Percent_Identity=47.6190476190476, Blast_Score=60, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACYP_THIDA (Q3SKG9)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_314617.1
- HSSP:   Q97ZL0
- ProteinModelPortal:   Q3SKG9
- SMR:   Q3SKG9
- STRING:   Q3SKG9
- GeneID:   3671623
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_0859
- NMPDR:   fig|292415.3.peg.287
- eggNOG:   COG1254
- HOGENOM:   HBG750266
- OMA:   EALIGWA
- PhylomeDB:   Q3SKG9
- ProtClustDB:   CLSK2770242
- BioCyc:   TDEN292415:TBD_0859-MONOMER
- HAMAP:   MF_01450
- InterPro:   IPR020456
- InterPro:   IPR001792
- InterPro:   IPR017968
- PANTHER:   PTHR10029
- PRINTS:   PR00112

Pfam domain/function: PF00708 Acylphosphatase; SSF54975 Acylphosphatase

EC number: =3.6.1.7

Molecular weight: Translated: 9981; Mature: 9981

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00150 ACYLPHOSPHATASE_1; PS00151 ACYLPHOSPHATASE_2; PS51160 ACYLPHOSPHATASE_3

Important sites: ACT_SITE 18-18 ACT_SITE 36-36

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLHLQIEGRVQGVWFRESMRREAERLGVDGWVRNRPDGSVEAVVQGTDEAVAALVAWA
CCEEEEEECCEEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHH
KMGPPLAHVERVDLSETEGEYSGFEKRSD
HCCCCHHHHEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKTLHLQIEGRVQGVWFRESMRREAERLGVDGWVRNRPDGSVEAVVQGTDEAVAALVAWA
CCEEEEEECCEEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHH
KMGPPLAHVERVDLSETEGEYSGFEKRSD
HCCCCHHHHEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA