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The map label for this gene is glnS [H]

Identifier: 74316868

GI number: 74316868

Start: 899113

End: 900810

Strand: Reverse

Name: glnS [H]

Synonym: Tbd_0850

Alternate gene names: 74316868

Gene position: 900810-899113 (Counterclockwise)

Preceding gene: 74316869

Following gene: 74316866

Centisome position: 30.96

GC content: 63.66

Gene sequence:

>1698_bases
ATGTCGCACGACAACGCTCCCGCGCCCGCCGCCAACTTCATCCGCAACATCATCGACGAGCAGAACGCCGAAGGAAAATG
GGGCGGCCGCGTCGAGACGCGCTTCCCGCCCGAGCCGAACGGCTACCTGCACCTCGGCCACGCGAAGTCCATCTTCCTCA
ACTTCGGGCTTGCGCGCGACTACGGCGGCGTCTGCCACCTGCGCTTCGACGACACCAACCCCGAGAAGGAAGAGCAGGAA
TATGTCGACGCGATCACTGAATCGGTAAAGTGGCTCGGCTTCGACTGGGGCGAGCATCTTTACTATGCGTCGAACTACTT
CGACACCATGTATGCCTGCGCCGAGCACCTGATCACGGCCGGCCACGCGTACGTCGATTCGCTCACGGCCGAGGAGATGC
GCGAATACCGCGGCACGCTCACGGAAAAGGGCAAGGACAGCCCCTATCGGAGTCGTTCAATCGAGGAGAACCTGGACCTC
TTCCGCAAAATGCGCGCCGGCGAATTCCCCGATGGCGCGCATGTGCTGCGGGCCAAGATCGACATGGCCTCGCCCAACAT
CAACCTGCGCGATCCGGCGATCTATCGCATCAAGCGCGCCCACCACCACAACACCGGCGACAAATGGTGCATCTACCCGA
TGTACACCTACGCGCATCCAATTGAAGATGCGATCGAGCACATCACCCACTCGATCTGCACCCTCGAATTCGAGGACCAG
CGCCCGTTCTACGACTGGCTGCTGGACAAGCTCGCCATCGGCGGCTTCTTCAGCCGCCCGCTGCCGCAGCAGATCGAGTT
CGCGCGGCTCAACCTCACCTACGTCATGCTTTCGAAGCGCAAGCTGATCCAATTGGTCGAAGAGAAGCACGTCTCCGGCT
GGGACGACCCGCGCATGCCGACCCTCGTCGGCGCGCGGCGGCGCGGCTACACGCCCGAAGGCCTCCGCCGCTTCACCGAC
CAGATCGGCGTGTCGAAGTCCGACGGCTGGATCGACTACAGCGTGTTCGAAGCCTGCCAGCGCGATGTCTTGAACGATTC
CGCGCCGCGTCGCGTCGCCGTCCTCGACCCGGTCAAGCTCGTCATCGACAACTACCCCGAAGGCCAGAGCGAAGACTGCT
TCGCCCCCAACCACCCGCAGCAGCCGGAGCTCGGCAAGCGCGCGATTCCGTTCTCGAAAGAACTGTGGATCGAGCGCGAG
GACTTCGAGGAGACGCCGCCCAAGGGCTACTTCCGCCTCTTCCCAGGCAACTCGGTGCGTCTACGCTACGGCTACGTCGT
CAAGTGCACCGGCTTTGACCGCGACGCCGACGGCAACATCGCAGCCGTGCACTGCGAATACCTGCCCGACACCAAGTCCG
GCACCCCCGGCGCCGACTCGGTCAAGGTCAAGGGAAATATCCATTGGGTGAGCGCGGCCCACGCCCACGACGCAGAAGTC
CGTCTCTACGACCGCCTGTTCAAGACCGCGCAGCCCGGCGCCGAAACCGGCAACTTCCTCGACGACCTCAACGCCGACTC
GGTGAAGGTCATCCGCGCGCAACTGGAACCGGCGCTCAAGGACGCCGCGCCCGAAGCTTCGTTTCAGTTCGAGCGGCACG
GCTACTTCGTCGCGGATCGGGTCGATACGCAGCCGGGCGCGCCGGTGTTCAACCGGACCGTGACGTTGAAGGATTCGTGG
GTGAAGGTTGGCAGTTAG

Upstream 100 bases:

>100_bases
CGGCCAGTCGGTCGTTCTCTACGACGGCGACGTCTGTCTGGGCGGCGGCATCATCTGCTGAACCCGCTACAATCCACGCA
TTCCAGACCTGCATTCCGCC

Downstream 100 bases:

>100_bases
CCTGTCGGTTGCAGCCTGACCGCTCGCGTCGAACCGCACTTCTCGGCCAAAGCAGACGAAATGACCTACCGCTCATCAGT
GAGCCATTTGCCAAGAATGG

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 565; Mature: 564

Protein sequence:

>565_residues
MSHDNAPAPAANFIRNIIDEQNAEGKWGGRVETRFPPEPNGYLHLGHAKSIFLNFGLARDYGGVCHLRFDDTNPEKEEQE
YVDAITESVKWLGFDWGEHLYYASNYFDTMYACAEHLITAGHAYVDSLTAEEMREYRGTLTEKGKDSPYRSRSIEENLDL
FRKMRAGEFPDGAHVLRAKIDMASPNINLRDPAIYRIKRAHHHNTGDKWCIYPMYTYAHPIEDAIEHITHSICTLEFEDQ
RPFYDWLLDKLAIGGFFSRPLPQQIEFARLNLTYVMLSKRKLIQLVEEKHVSGWDDPRMPTLVGARRRGYTPEGLRRFTD
QIGVSKSDGWIDYSVFEACQRDVLNDSAPRRVAVLDPVKLVIDNYPEGQSEDCFAPNHPQQPELGKRAIPFSKELWIERE
DFEETPPKGYFRLFPGNSVRLRYGYVVKCTGFDRDADGNIAAVHCEYLPDTKSGTPGADSVKVKGNIHWVSAAHAHDAEV
RLYDRLFKTAQPGAETGNFLDDLNADSVKVIRAQLEPALKDAAPEASFQFERHGYFVADRVDTQPGAPVFNRTVTLKDSW
VKVGS

Sequences:

>Translated_565_residues
MSHDNAPAPAANFIRNIIDEQNAEGKWGGRVETRFPPEPNGYLHLGHAKSIFLNFGLARDYGGVCHLRFDDTNPEKEEQE
YVDAITESVKWLGFDWGEHLYYASNYFDTMYACAEHLITAGHAYVDSLTAEEMREYRGTLTEKGKDSPYRSRSIEENLDL
FRKMRAGEFPDGAHVLRAKIDMASPNINLRDPAIYRIKRAHHHNTGDKWCIYPMYTYAHPIEDAIEHITHSICTLEFEDQ
RPFYDWLLDKLAIGGFFSRPLPQQIEFARLNLTYVMLSKRKLIQLVEEKHVSGWDDPRMPTLVGARRRGYTPEGLRRFTD
QIGVSKSDGWIDYSVFEACQRDVLNDSAPRRVAVLDPVKLVIDNYPEGQSEDCFAPNHPQQPELGKRAIPFSKELWIERE
DFEETPPKGYFRLFPGNSVRLRYGYVVKCTGFDRDADGNIAAVHCEYLPDTKSGTPGADSVKVKGNIHWVSAAHAHDAEV
RLYDRLFKTAQPGAETGNFLDDLNADSVKVIRAQLEPALKDAAPEASFQFERHGYFVADRVDTQPGAPVFNRTVTLKDSW
VKVGS
>Mature_564_residues
SHDNAPAPAANFIRNIIDEQNAEGKWGGRVETRFPPEPNGYLHLGHAKSIFLNFGLARDYGGVCHLRFDDTNPEKEEQEY
VDAITESVKWLGFDWGEHLYYASNYFDTMYACAEHLITAGHAYVDSLTAEEMREYRGTLTEKGKDSPYRSRSIEENLDLF
RKMRAGEFPDGAHVLRAKIDMASPNINLRDPAIYRIKRAHHHNTGDKWCIYPMYTYAHPIEDAIEHITHSICTLEFEDQR
PFYDWLLDKLAIGGFFSRPLPQQIEFARLNLTYVMLSKRKLIQLVEEKHVSGWDDPRMPTLVGARRRGYTPEGLRRFTDQ
IGVSKSDGWIDYSVFEACQRDVLNDSAPRRVAVLDPVKLVIDNYPEGQSEDCFAPNHPQQPELGKRAIPFSKELWIERED
FEETPPKGYFRLFPGNSVRLRYGYVVKCTGFDRDADGNIAAVHCEYLPDTKSGTPGADSVKVKGNIHWVSAAHAHDAEVR
LYDRLFKTAQPGAETGNFLDDLNADSVKVIRAQLEPALKDAAPEASFQFERHGYFVADRVDTQPGAPVFNRTVTLKDSWV
KVGS

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=541, Percent_Identity=45.1016635859519, Blast_Score=423, Evalue=1e-118,
Organism=Homo sapiens, GI62241042, Length=523, Percent_Identity=35.9464627151052, Blast_Score=283, Evalue=4e-76,
Organism=Escherichia coli, GI1786895, Length=560, Percent_Identity=57.8571428571429, Blast_Score=648, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=123, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17543332, Length=539, Percent_Identity=42.1150278293135, Blast_Score=397, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17511007, Length=517, Percent_Identity=32.6885880077369, Blast_Score=251, Evalue=7e-67,
Organism=Saccharomyces cerevisiae, GI6324742, Length=575, Percent_Identity=40.695652173913, Blast_Score=397, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6321192, Length=520, Percent_Identity=35.3846153846154, Blast_Score=281, Evalue=2e-76,
Organism=Drosophila melanogaster, GI17864488, Length=539, Percent_Identity=42.6716141001855, Blast_Score=410, Evalue=1e-114,
Organism=Drosophila melanogaster, GI24649466, Length=432, Percent_Identity=37.7314814814815, Blast_Score=258, Evalue=7e-69,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 64343; Mature: 64211

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHDNAPAPAANFIRNIIDEQNAEGKWGGRVETRFPPEPNGYLHLGHAKSIFLNFGLARD
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCEEEECCCEEEEEECCEECC
YGGVCHLRFDDTNPEKEEQEYVDAITESVKWLGFDWGEHLYYASNYFDTMYACAEHLITA
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHH
GHAYVDSLTAEEMREYRGTLTEKGKDSPYRSRSIEENLDLFRKMRAGEFPDGAHVLRAKI
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCHHHHHHHHHHHHCCCCCCCCCEEEEEE
DMASPNINLRDPAIYRIKRAHHHNTGDKWCIYPMYTYAHPIEDAIEHITHSICTLEFEDQ
EECCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEHHHHCCCHHHHHHHHHHHHEEEEECCC
RPFYDWLLDKLAIGGFFSRPLPQQIEFARLNLTYVMLSKRKLIQLVEEKHVSGWDDPRMP
CCHHHHHHHHHHHCCHHCCCCCHHHEEEEEEEEEEEHHHHHHHHHHHHHCCCCCCCCCCC
TLVGARRRGYTPEGLRRFTDQIGVSKSDGWIDYSVFEACQRDVLNDSAPRRVAVLDPVKL
HHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHCCCCCCEEEEECCHHH
VIDNYPEGQSEDCFAPNHPQQPELGKRAIPFSKELWIEREDFEETPPKGYFRLFPGNSVR
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCEEHHCCCCCCCCCEEEECCCCEEE
LRYGYVVKCTGFDRDADGNIAAVHCEYLPDTKSGTPGADSVKVKGNIHWVSAAHAHDAEV
EEEEEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEECEEEEEEECCCCCCHH
RLYDRLFKTAQPGAETGNFLDDLNADSVKVIRAQLEPALKDAAPEASFQFERHGYFVADR
HHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEEC
VDTQPGAPVFNRTVTLKDSWVKVGS
CCCCCCCCHHCEEEEEECCEEECCC
>Mature Secondary Structure 
SHDNAPAPAANFIRNIIDEQNAEGKWGGRVETRFPPEPNGYLHLGHAKSIFLNFGLARD
CCCCCCCCHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCEEEECCCEEEEEECCEECC
YGGVCHLRFDDTNPEKEEQEYVDAITESVKWLGFDWGEHLYYASNYFDTMYACAEHLITA
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHH
GHAYVDSLTAEEMREYRGTLTEKGKDSPYRSRSIEENLDLFRKMRAGEFPDGAHVLRAKI
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCHHHHHHHHHHHHCCCCCCCCCEEEEEE
DMASPNINLRDPAIYRIKRAHHHNTGDKWCIYPMYTYAHPIEDAIEHITHSICTLEFEDQ
EECCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEHHHHCCCHHHHHHHHHHHHEEEEECCC
RPFYDWLLDKLAIGGFFSRPLPQQIEFARLNLTYVMLSKRKLIQLVEEKHVSGWDDPRMP
CCHHHHHHHHHHHCCHHCCCCCHHHEEEEEEEEEEEHHHHHHHHHHHHHCCCCCCCCCCC
TLVGARRRGYTPEGLRRFTDQIGVSKSDGWIDYSVFEACQRDVLNDSAPRRVAVLDPVKL
HHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHCCCCCCEEEEECCHHH
VIDNYPEGQSEDCFAPNHPQQPELGKRAIPFSKELWIEREDFEETPPKGYFRLFPGNSVR
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCEEHHCCCCCCCCCEEEECCCCEEE
LRYGYVVKCTGFDRDADGNIAAVHCEYLPDTKSGTPGADSVKVKGNIHWVSAAHAHDAEV
EEEEEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEECEEEEEEECCCCCCHH
RLYDRLFKTAQPGAETGNFLDDLNADSVKVIRAQLEPALKDAAPEASFQFERHGYFVADR
HHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEEC
VDTQPGAPVFNRTVTLKDSWVKVGS
CCCCCCCCHHCEEEEEECCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA