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The map label for this gene is tesA [C]

Identifier: 74316704

GI number: 74316704

Start: 727386

End: 728006

Strand: Direct

Name: tesA [C]

Synonym: Tbd_0686

Alternate gene names: 74316704

Gene position: 727386-728006 (Clockwise)

Preceding gene: 74316701

Following gene: 74316705

Centisome position: 25.0

GC content: 69.24

Gene sequence:

>621_bases
ATGGATTATCGCGTGTGGAGCTTGTTGTTGCTGTTGTTGCCCGGTTCGGCGGCGGCCGCCTCGTGCTCGCTGTTGATCCT
CGGCGACAGCTTGAGTTCCGGCTACGGGCTCGCCGCGGGGCAGGGCTGGGTCGACCGGCTGCGGGCCCGCATGCGCGACG
CGGCGCCCGACTGGCGCGTCGTCAACGCGAGCGTGAGCGGCGACACGACGCAGAACGGGTTGCAGCGGCTCGAACCGACG
CTGCAGCGGCAGCGTCCCCAAGGGGTCGTGATCGAGCTCGGCGGCAACGACGCCTTGCGCGGCACGCCCCCCGCGCAGAT
CCGTCGCAATCTCGTCACGCTGGTGCGGCAGGCGAAGGCGAGCGGCGCCTGGGTGTTGCTGCTCGAGCCGCCGGTGTTGC
CGAATTACGGCCGCGCCTACGCCGATGCGGTCGCCAGACTCGCGGCCGAGGTTGCGCGCAGTGAAAAGGTCACCCACGTG
CCGTGCTTCGTCTGCGAGGTCGGCGTGAAGCCGGGGATGATGCAGCCCGACGGCATCCATCCGAACGAAAAAGGGCAGTC
CGGCATGCTCGAGGCCGTCTGGCCCTACCTCCGTCCCAAGCTGGAGTGCCCCGGCAAATGA

Upstream 100 bases:

>100_bases
TCGGCACGCGCTGGGACAGCGCGCGCGCGCTCACGATCGTGGCGGGGAACTGGGCGGGGTCGGCATGCGTCATCGAGGGG
GTGTCGCGGAAGGAGGATGG

Downstream 100 bases:

>100_bases
AGCGGCCCGTCGAGGGCTGCACGTGCGGGTCCGGCCGGCCCTACGAGGCCTGCTGCGGCCGCTATCATGCCGGCGAGCCG
CCGGCCGATGCGGAGACCTT

Product: acyl-CoA thioesterase I

Products: NA

Alternate protein names: Aryl-ester hydrolase [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MDYRVWSLLLLLLPGSAAAASCSLLILGDSLSSGYGLAAGQGWVDRLRARMRDAAPDWRVVNASVSGDTTQNGLQRLEPT
LQRQRPQGVVIELGGNDALRGTPPAQIRRNLVTLVRQAKASGAWVLLLEPPVLPNYGRAYADAVARLAAEVARSEKVTHV
PCFVCEVGVKPGMMQPDGIHPNEKGQSGMLEAVWPYLRPKLECPGK

Sequences:

>Translated_206_residues
MDYRVWSLLLLLLPGSAAAASCSLLILGDSLSSGYGLAAGQGWVDRLRARMRDAAPDWRVVNASVSGDTTQNGLQRLEPT
LQRQRPQGVVIELGGNDALRGTPPAQIRRNLVTLVRQAKASGAWVLLLEPPVLPNYGRAYADAVARLAAEVARSEKVTHV
PCFVCEVGVKPGMMQPDGIHPNEKGQSGMLEAVWPYLRPKLECPGK
>Mature_206_residues
MDYRVWSLLLLLLPGSAAAASCSLLILGDSLSSGYGLAAGQGWVDRLRARMRDAAPDWRVVNASVSGDTTQNGLQRLEPT
LQRQRPQGVVIELGGNDALRGTPPAQIRRNLVTLVRQAKASGAWVLLLEPPVLPNYGRAYADAVARLAAEVARSEKVTHV
PCFVCEVGVKPGMMQPDGIHPNEKGQSGMLEAVWPYLRPKLECPGK

Specific function: Favors the hydrolysis of several arylesters [H]

COG id: COG2755

COG function: function code E; Lysophospholipase L1 and related esterases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDSL' lipolytic enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1786702, Length=192, Percent_Identity=41.1458333333333, Blast_Score=139, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013830
- InterPro:   IPR013831
- InterPro:   IPR001087
- InterPro:   IPR008265 [H]

Pfam domain/function: PF00657 Lipase_GDSL [H]

EC number: =3.1.1.2 [H]

Molecular weight: Translated: 22216; Mature: 22216

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYRVWSLLLLLLPGSAAAASCSLLILGDSLSSGYGLAAGQGWVDRLRARMRDAAPDWRV
CCHHHHHHHHHHCCCCCHHHEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEE
VNASVSGDTTQNGLQRLEPTLQRQRPQGVVIELGGNDALRGTPPAQIRRNLVTLVRQAKA
EEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCC
SGAWVLLLEPPVLPNYGRAYADAVARLAAEVARSEKVTHVPCFVCEVGVKPGMMQPDGIH
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCC
PNEKGQSGMLEAVWPYLRPKLECPGK
CCCCCCCCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MDYRVWSLLLLLLPGSAAAASCSLLILGDSLSSGYGLAAGQGWVDRLRARMRDAAPDWRV
CCHHHHHHHHHHCCCCCHHHEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEE
VNASVSGDTTQNGLQRLEPTLQRQRPQGVVIELGGNDALRGTPPAQIRRNLVTLVRQAKA
EEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCC
SGAWVLLLEPPVLPNYGRAYADAVARLAAEVARSEKVTHVPCFVCEVGVKPGMMQPDGIH
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCC
PNEKGQSGMLEAVWPYLRPKLECPGK
CCCCCCCCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8141782 [H]