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The map label for this gene is aroG [H]

Identifier: 74316532

GI number: 74316532

Start: 543458

End: 544534

Strand: Direct

Name: aroG [H]

Synonym: Tbd_0514

Alternate gene names: 74316532

Gene position: 543458-544534 (Clockwise)

Preceding gene: 74316531

Following gene: 74316533

Centisome position: 18.68

GC content: 66.76

Gene sequence:

>1077_bases
ATGTCTGCCACCCGAACCGACGACACCCGCATCGAGCAAAGCGGCGAACTGCTTGCGCCGATGCAGATCATGCGCGAGCT
GCGCGCGAGCGAGGCCGTCCATGCGCACGTCGCGCGCGCGCGCGGCGCGATCCACGACGTCCTGCGTGGCGCCGACGACC
GCATGTTCGTCGTCGTCGGCCCCTGCTCGATCCACGACCCCGAGGCCGCGCTCGACTACGCGCGCAAGCTCAAGCCCCTC
GCTGACGAGCTCGCGCACGAACTCATCGTCGTGATGCGGGTGTATTTCGAGAAGCCGCGCACGACCGTCGGCTGGAAAGG
GCTCATCAACGATCCCCATCTCGACGAGAGCTTCGACATCAACGAGGGCCTGCGGCTCGCGCGAAAATTGTTGCTGGAGA
TCAACGAAATCGGACTGCCCTGTGCGACCGAATTCCTCGACCTGATCTCGCCGCAGTACATCGCCGACCTCGTGAGCTGG
GGTGCGATCGGTGCGCGCACGACCGAGTCGCAGTCGCATCGCCAGCTCGCGTCGGGGCTGTCGTGTCCCGTCGGCTTCAA
GAACGGCACCGACGGCAGTCTGCGGATCGCGGTCGACGCGATCAAGGCCGCGGCGGCGCGCCACCATTTCATCTCGGTCA
CCAAGTCGGGCCACGTCGGCGTCTTCAGCACCTCGGGCAACGAGGACGCCCACGTCATCCTGCGCGGCGGCAAGGCGCCG
AACTACGACGCGGCGAGCGTCAATCTCGCGAGCGGCGAGCTGGCGGCGGCGGGTCTCAGACAGCAACTGATGATCGATTT
CTCGCACGCCAATTCGAGCAAGCAGTACCAGCGCCAGATCGAAGTCGCCGCCGACGTCGCCGCTCAAATCGCGGGCGGCG
ACACCCGCATCATCGGGGCGATGGTCGAGAGCCACCTCAATCCGGGCCGTCAGGACCTCGTCCCGGGGCAGTCGCTCGAG
TATGCGAAGTCGATCACCGACGCGTGCATCGGGTGGGAGGACACGATTCCCCTGCTGCGCACGCTCGCCGACGCGGTGAA
AAAACGCCGGCTGGCCGCGCCGGCGGATGAGGAATGA

Upstream 100 bases:

>100_bases
GCTGAAGCGAACAGCACGGCCTTCACGAAACCGCCAGCCCGCTGGCGGTTTTTTTGTCTGCCGAGCCGCCGCGGGTAATC
AAAACGAACGGAGCCTGAAC

Downstream 100 bases:

>100_bases
GCGCGCTTACGGGGTAAAATGCGCGTGGCGGGCCTCCCCGCATGGCTAAGTCGTGAATCGGGTCAGGTCCGGAAGGAAGC
AGCCACAGCGATCCATGCCA

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MSATRTDDTRIEQSGELLAPMQIMRELRASEAVHAHVARARGAIHDVLRGADDRMFVVVGPCSIHDPEAALDYARKLKPL
ADELAHELIVVMRVYFEKPRTTVGWKGLINDPHLDESFDINEGLRLARKLLLEINEIGLPCATEFLDLISPQYIADLVSW
GAIGARTTESQSHRQLASGLSCPVGFKNGTDGSLRIAVDAIKAAAARHHFISVTKSGHVGVFSTSGNEDAHVILRGGKAP
NYDAASVNLASGELAAAGLRQQLMIDFSHANSSKQYQRQIEVAADVAAQIAGGDTRIIGAMVESHLNPGRQDLVPGQSLE
YAKSITDACIGWEDTIPLLRTLADAVKKRRLAAPADEE

Sequences:

>Translated_358_residues
MSATRTDDTRIEQSGELLAPMQIMRELRASEAVHAHVARARGAIHDVLRGADDRMFVVVGPCSIHDPEAALDYARKLKPL
ADELAHELIVVMRVYFEKPRTTVGWKGLINDPHLDESFDINEGLRLARKLLLEINEIGLPCATEFLDLISPQYIADLVSW
GAIGARTTESQSHRQLASGLSCPVGFKNGTDGSLRIAVDAIKAAAARHHFISVTKSGHVGVFSTSGNEDAHVILRGGKAP
NYDAASVNLASGELAAAGLRQQLMIDFSHANSSKQYQRQIEVAADVAAQIAGGDTRIIGAMVESHLNPGRQDLVPGQSLE
YAKSITDACIGWEDTIPLLRTLADAVKKRRLAAPADEE
>Mature_357_residues
SATRTDDTRIEQSGELLAPMQIMRELRASEAVHAHVARARGAIHDVLRGADDRMFVVVGPCSIHDPEAALDYARKLKPLA
DELAHELIVVMRVYFEKPRTTVGWKGLINDPHLDESFDINEGLRLARKLLLEINEIGLPCATEFLDLISPQYIADLVSWG
AIGARTTESQSHRQLASGLSCPVGFKNGTDGSLRIAVDAIKAAAARHHFISVTKSGHVGVFSTSGNEDAHVILRGGKAPN
YDAASVNLASGELAAAGLRQQLMIDFSHANSSKQYQRQIEVAADVAAQIAGGDTRIIGAMVESHLNPGRQDLVPGQSLEY
AKSITDACIGWEDTIPLLRTLADAVKKRRLAAPADEE

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786969, Length=346, Percent_Identity=65.0289017341041, Blast_Score=466, Evalue=1e-133,
Organism=Escherichia coli, GI1787996, Length=345, Percent_Identity=53.0434782608696, Blast_Score=384, Evalue=1e-108,
Organism=Escherichia coli, GI1788953, Length=343, Percent_Identity=54.8104956268222, Blast_Score=382, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6319726, Length=348, Percent_Identity=54.0229885057471, Blast_Score=363, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6320240, Length=357, Percent_Identity=48.7394957983193, Blast_Score=355, Evalue=6e-99,

Paralogues:

None

Copy number: 600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38703; Mature: 38572

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATRTDDTRIEQSGELLAPMQIMRELRASEAVHAHVARARGAIHDVLRGADDRMFVVVG
CCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
PCSIHDPEAALDYARKLKPLADELAHELIVVMRVYFEKPRTTVGWKGLINDPHLDESFDI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCH
NEGLRLARKLLLEINEIGLPCATEFLDLISPQYIADLVSWGAIGARTTESQSHRQLASGL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCC
SCPVGFKNGTDGSLRIAVDAIKAAAARHHFISVTKSGHVGVFSTSGNEDAHVILRGGKAP
CCCCCCCCCCCCEEEEHHHHHHHHHHHHHEEEEECCCCEEEEECCCCCCCEEEEECCCCC
NYDAASVNLASGELAAAGLRQQLMIDFSHANSSKQYQRQIEVAADVAAQIAGGDTRIIGA
CCCCCEEEECCCHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
MVESHLNPGRQDLVPGQSLEYAKSITDACIGWEDTIPLLRTLADAVKKRRLAAPADEE
HHHHHCCCCHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SATRTDDTRIEQSGELLAPMQIMRELRASEAVHAHVARARGAIHDVLRGADDRMFVVVG
CCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
PCSIHDPEAALDYARKLKPLADELAHELIVVMRVYFEKPRTTVGWKGLINDPHLDESFDI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCH
NEGLRLARKLLLEINEIGLPCATEFLDLISPQYIADLVSWGAIGARTTESQSHRQLASGL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCC
SCPVGFKNGTDGSLRIAVDAIKAAAARHHFISVTKSGHVGVFSTSGNEDAHVILRGGKAP
CCCCCCCCCCCCEEEEHHHHHHHHHHHHHEEEEECCCCEEEEECCCCCCCEEEEECCCCC
NYDAASVNLASGELAAAGLRQQLMIDFSHANSSKQYQRQIEVAADVAAQIAGGDTRIIGA
CCCCCEEEECCCHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
MVESHLNPGRQDLVPGQSLEYAKSITDACIGWEDTIPLLRTLADAVKKRRLAAPADEE
HHHHHCCCCHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]