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The map label for this gene is ttuD [H]

Identifier: 74316451

GI number: 74316451

Start: 452112

End: 453386

Strand: Reverse

Name: ttuD [H]

Synonym: Tbd_0433

Alternate gene names: 74316451

Gene position: 453386-452112 (Counterclockwise)

Preceding gene: 74316452

Following gene: 74316401

Centisome position: 15.58

GC content: 72.31

Gene sequence:

>1275_bases
TTGCGCGGTCCGGTGAATCCACGCGAACTCCTGCTCGGCTCCTTTCGGGCCGCCGTCGCCGCCGCGGCGCCCGCGGCCGT
GCTCCCGGCTCATCTGCCGCAGCCGCCGCGGGGCCGGACCCTCGTCCTCGGGGGCGGCAAGGCCGCGGCGGCGATGGCGG
CGGCCGTCGAAGCCAGCTGGCCCGCCGACGCGGCGCTCTCGGGGCTGGTCGTGACCCGCTACGCGCATGGCTGCGCGACG
ACGCGCATCGAAGTCGTCGAGGCCAGCCATCCCCTGCCCGACAGCCGCGGCGAAGCCGCAGCCCTGCGCATGCTTGAAAT
GGCGGGGGAACTCGGCGCGGACGATCTGCTGCTTGCCCTGATCTCAGGCGGGGGGTCGAGTCTGCTCGCCGCGCCCGTCG
ACGGCGTGACGCTGAAGGAATTGCGTCAGCTCACCAAGGCGCTGCTCGGCGCCGGCGCGACGATCCAGGAGATCAACACG
GTGCGCAAGCACCTGACGCGGCTGTCCGGGGGACGCCTCGCCCGGGCGGCAGCGGGCGCGCAGGTGCTCGCGCTGATCGT
CTCGGACGTCGTCGGCGACGATCCGACGCACATCGCGTCGGGGCCGTGCGCGCCCGATTCGACGACGTGCGCTGACGCAC
TCGACGCTTTGCGACGTTTCGAGGTCGCCGCACCGCCGTCCGTGCAACGCCACCTCGACGCCTGCGCGGCGGGCAGCATC
GAGGACACGCCAAAACCCGGCGACCCCTGCTTCACGCGCGTGGACAATCGCGTGATCGCGAGCGCCGGCCGTAGCCTGCA
GGCCGCCGCCGACTACTTAGAGGGCCAGGGAATCCGCGTCGTGCTGCTATCCGACCGGGTCAGCGGCGACGCACGAACCG
TCGCGAAGCAGCACGCCGCGCTCGTCCGTACGCTGCGGGCGCGCGGTCCCCTCGCGCTGATTTCGGGTGGCGAAACGACC
GTGCGTCTCGCCCGCCATGCAGGCCACGGCGGCCGCAACACCGAATTTCTGCTCGCCCTCGCGACGGCCTTCGATCACGC
CCCGGTCGCCGCCATCGCCGCCGACACCGACGGCGTCGACGGCAGCGAGGACAACGCCGGCGCGTTGCTCTTTCCGGACA
CGATGGCGCGCGCCCGCGCTCAAGGACTCGATCCGCATGCCTGCCTCGCGGCGCAGGACAGTTACGGCTTTTTTTCCGCG
CTCGGCGACCTCGTCGTCACCGGCCCGACCCGCACCAACGTCAACGACTACCGCGCGGTGCTGCTCGGGGTCTAG

Upstream 100 bases:

>100_bases
AAGGCGCGGGAAGCGGCGAACTGAACCGCTGCAACCGCCGGGCGCGAACGCGCCGAGGCCGCCCTCCCGCCGCCGGTGCA
GGCGACTTCGCGCTCGCCCG

Downstream 100 bases:

>100_bases
CCGCGCTGAGTCCGGCCGCCTCTCCGCCCAGCCAGGACGACGGCGAACGTTTGCCCTGGTCAGAGTCTCGCCTCGGTCAG
TTCGGCCGCTGCACGCGCAC

Product: hydroxypyruvate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MRGPVNPRELLLGSFRAAVAAAAPAAVLPAHLPQPPRGRTLVLGGGKAAAAMAAAVEASWPADAALSGLVVTRYAHGCAT
TRIEVVEASHPLPDSRGEAAALRMLEMAGELGADDLLLALISGGGSSLLAAPVDGVTLKELRQLTKALLGAGATIQEINT
VRKHLTRLSGGRLARAAAGAQVLALIVSDVVGDDPTHIASGPCAPDSTTCADALDALRRFEVAAPPSVQRHLDACAAGSI
EDTPKPGDPCFTRVDNRVIASAGRSLQAAADYLEGQGIRVVLLSDRVSGDARTVAKQHAALVRTLRARGPLALISGGETT
VRLARHAGHGGRNTEFLLALATAFDHAPVAAIAADTDGVDGSEDNAGALLFPDTMARARAQGLDPHACLAAQDSYGFFSA
LGDLVVTGPTRTNVNDYRAVLLGV

Sequences:

>Translated_424_residues
MRGPVNPRELLLGSFRAAVAAAAPAAVLPAHLPQPPRGRTLVLGGGKAAAAMAAAVEASWPADAALSGLVVTRYAHGCAT
TRIEVVEASHPLPDSRGEAAALRMLEMAGELGADDLLLALISGGGSSLLAAPVDGVTLKELRQLTKALLGAGATIQEINT
VRKHLTRLSGGRLARAAAGAQVLALIVSDVVGDDPTHIASGPCAPDSTTCADALDALRRFEVAAPPSVQRHLDACAAGSI
EDTPKPGDPCFTRVDNRVIASAGRSLQAAADYLEGQGIRVVLLSDRVSGDARTVAKQHAALVRTLRARGPLALISGGETT
VRLARHAGHGGRNTEFLLALATAFDHAPVAAIAADTDGVDGSEDNAGALLFPDTMARARAQGLDPHACLAAQDSYGFFSA
LGDLVVTGPTRTNVNDYRAVLLGV
>Mature_424_residues
MRGPVNPRELLLGSFRAAVAAAAPAAVLPAHLPQPPRGRTLVLGGGKAAAAMAAAVEASWPADAALSGLVVTRYAHGCAT
TRIEVVEASHPLPDSRGEAAALRMLEMAGELGADDLLLALISGGGSSLLAAPVDGVTLKELRQLTKALLGAGATIQEINT
VRKHLTRLSGGRLARAAAGAQVLALIVSDVVGDDPTHIASGPCAPDSTTCADALDALRRFEVAAPPSVQRHLDACAAGSI
EDTPKPGDPCFTRVDNRVIASAGRSLQAAADYLEGQGIRVVLLSDRVSGDARTVAKQHAALVRTLRARGPLALISGGETT
VRLARHAGHGGRNTEFLLALATAFDHAPVAAIAADTDGVDGSEDNAGALLFPDTMARARAQGLDPHACLAAQDSYGFFSA
LGDLVVTGPTRTNVNDYRAVLLGV

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=486, Percent_Identity=34.7736625514403, Blast_Score=187, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI193205461, Length=417, Percent_Identity=29.0167865707434, Blast_Score=158, Evalue=4e-39,
Organism=Drosophila melanogaster, GI19920578, Length=445, Percent_Identity=31.685393258427, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 43309; Mature: 43309

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGPVNPRELLLGSFRAAVAAAAPAAVLPAHLPQPPRGRTLVLGGGKAAAAMAAAVEASW
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHCCC
PADAALSGLVVTRYAHGCATTRIEVVEASHPLPDSRGEAAALRMLEMAGELGADDLLLAL
CHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
ISGGGSSLLAAPVDGVTLKELRQLTKALLGAGATIQEINTVRKHLTRLSGGRLARAAAGA
HHCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
QVLALIVSDVVGDDPTHIASGPCAPDSTTCADALDALRRFEVAAPPSVQRHLDACAAGSI
HHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
EDTPKPGDPCFTRVDNRVIASAGRSLQAAADYLEGQGIRVVLLSDRVSGDARTVAKQHAA
CCCCCCCCHHHHHHCCHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHH
LVRTLRARGPLALISGGETTVRLARHAGHGGRNTEFLLALATAFDHAPVAAIAADTDGVD
HHHHHHHCCCEEEEECCCHHHHHHHHCCCCCCCCHHEEHEEHHHCCCCEEEEEECCCCCC
GSEDNAGALLFPDTMARARAQGLDPHACLAAQDSYGFFSALGDLVVTGPTRTNVNDYRAV
CCCCCCCEEECCHHHHHHHHCCCCCHHEEECCCCCHHHHHHCCEEEECCCCCCCCHHEEE
LLGV
EECC
>Mature Secondary Structure
MRGPVNPRELLLGSFRAAVAAAAPAAVLPAHLPQPPRGRTLVLGGGKAAAAMAAAVEASW
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHCCC
PADAALSGLVVTRYAHGCATTRIEVVEASHPLPDSRGEAAALRMLEMAGELGADDLLLAL
CHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
ISGGGSSLLAAPVDGVTLKELRQLTKALLGAGATIQEINTVRKHLTRLSGGRLARAAAGA
HHCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
QVLALIVSDVVGDDPTHIASGPCAPDSTTCADALDALRRFEVAAPPSVQRHLDACAAGSI
HHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
EDTPKPGDPCFTRVDNRVIASAGRSLQAAADYLEGQGIRVVLLSDRVSGDARTVAKQHAA
CCCCCCCCHHHHHHCCHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHH
LVRTLRARGPLALISGGETTVRLARHAGHGGRNTEFLLALATAFDHAPVAAIAADTDGVD
HHHHHHHCCCEEEEECCCHHHHHHHHCCCCCCCCHHEEHEEHHHCCCCEEEEEECCCCCC
GSEDNAGALLFPDTMARARAQGLDPHACLAAQDSYGFFSALGDLVVTGPTRTNVNDYRAV
CCCCCCCEEECCHHHHHHHHCCCCCHHEEECCCCCHHHHHHCCEEEECCCCCCCCHHEEE
LLGV
EECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]