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The map label for this gene is tolQ [H]

Identifier: 74316375

GI number: 74316375

Start: 387827

End: 389494

Strand: Direct

Name: tolQ [H]

Synonym: Tbd_0357

Alternate gene names: 74316375

Gene position: 387827-389494 (Clockwise)

Preceding gene: 74316374

Following gene: 74316376

Centisome position: 13.33

GC content: 66.85

Gene sequence:

>1668_bases
ATGCATGTCCTTGCCGTTGCGATTGCCTTGTTGCTTTCCCTGTTTTCCGCCGCGAGCCACGCGTGGTGGAACGAGGACTG
GAGCGCGCGCAAGAAGATCACGCTGACGAATCCGGCGGGCGAGATCGTCGACGCGCCGGTGCTGATCCGGCTGCACACCG
GCAATTTCGATTTCCTTTCGGCCAACGAGGACGGCAGCGATCTGCGCGTCGTCGGGGGGGACGACGCGACCGAGCTCAAG
TTCCACATCGAGAAATGGGATGGCCTGAACCAGCTTGCGCTGGTGTGGGTAAAGATGCCAAAACTCGCCGCGACGACCGA
GGCCTGGCTGTATTTCGGCAACCCGGAGGCGGCCGCATCCTCGGATGCGAAGGGCACCTACGACGCGGGAAGCGCGGTCT
TCCACTTCAACGAGGCGGGTGGCAACCCCACCGACAGCGCCCCGGCCGGGGCGAACGCCACGGCCTTCACTGGCACCCGG
ATCGCCGCCTCGTTCGCCAACGGCGGCGCCAAGTTCGATGCGACGCAAATCCTGACGTTGCCGGCGCTACCCGTGGCCGG
CGGCTGGAGCGCGTCGATGTGGCTGAAGCCGGCCGCGCTCGACGGCGCGTTGATGCAAGCGGGCGGATATTCGGCCGCTC
TGACGGGAGGCGTCCTGAACGTGCAGGCAGGCGCAGCGACCGTCGCGGCAGCCGTGCCGCTCGAGGTCGGAAAATGGCAG
CACGTCGCCGTGGTCGTCGAGGGCGGCACGCTCAGGCTTTATGTCGCCGGCAAGCCAGCGGGCGAGGCGGCCGGCGCGGC
TCTGCCCGCGGGGCCGCTTACGGTCGGCAGCGGCTACAACGGCGAGGCCGACGAAATTCAGCTCGCCGGTGCCGCACGCT
CCGCTGCCTGGATCGCGGTCGCGGCGGCGCAGGGTCCCGACGGCACGCTGGTCGCGCTGGGCGAGGACGAGAGCAGCGAA
GGCGGGGGGGGCGGCATCTGGGCCACGCTGTTCCGGGCGCTCACGCTCGACGGCTGGATCGCGATCGGCGTGCTCGCCGT
GATGCTGGTGGTCGCGGTGTGGGTCATGATTGCCAAGGCGGTGTACGTGAACCTCGTCGACGCGGCGAACCAGTCCTTTT
TGGAGAAATTTCGCGAGCTGTCGTCCGACCTCGGCGCGCTCGACAAGTCGACACAGATGGCCGACGCGTTCCGGCATTCC
TCGCTCTATCGCCTGTATCACATCGCCGCGCAGGAGCTGTCGCACCGCTTCAAGGACACCGACGCCAGCCATCTGGCAGA
GCACGACAAGAACCTCACGCCGCAGGCGCTCGATTCGATCCGCGCCAGCCTCGACACCGGCATGGTGCGCGAATCGGGAC
TGCTGACGCGATTGATGGTGCTGCTGACGATCGCGATTTCGGGCGGCCCGTTTATCGGTCTCTTGGGCACGGTGCTGGGC
GTGATGATCACGTTCGCGGTTATCGCCGCGACCGGCGACGTCAACGTCAACGCAATCGCACCGGGCATCGCGGCGGCACT
CATGGCGACGGCCGCGGGCATGGCGGTCGCGATCCCGGCGCTGTTCGGTTACAACTATCTCAACTCGCGCATCAAGACGA
TCACGTCGGACATGCGCGTGTTCATCGACGAGCTCGTGACCAAGCTCGCCGAAAACTACTCGCGCTAG

Upstream 100 bases:

>100_bases
CGCGGAAGGGGAGATGGTCCGTTTGGGCCATGTCCGCTTCCAGTCCCTGTCATCGCCCCCCCGTAGGATCAGCCGCTTGC
CCGATTCCGGTTGAAGCCCT

Downstream 100 bases:

>100_bases
GACGGACGCCATGGCCAGCGCGCACGACGACAACGAACCTTACGACGAGATCAACATCACGCCGATGCTCGACCTGGCAT
ACGTGCTGCTCGTCATCTTC

Product: putative transport protein ExbB2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 555; Mature: 555

Protein sequence:

>555_residues
MHVLAVAIALLLSLFSAASHAWWNEDWSARKKITLTNPAGEIVDAPVLIRLHTGNFDFLSANEDGSDLRVVGGDDATELK
FHIEKWDGLNQLALVWVKMPKLAATTEAWLYFGNPEAAASSDAKGTYDAGSAVFHFNEAGGNPTDSAPAGANATAFTGTR
IAASFANGGAKFDATQILTLPALPVAGGWSASMWLKPAALDGALMQAGGYSAALTGGVLNVQAGAATVAAAVPLEVGKWQ
HVAVVVEGGTLRLYVAGKPAGEAAGAALPAGPLTVGSGYNGEADEIQLAGAARSAAWIAVAAAQGPDGTLVALGEDESSE
GGGGGIWATLFRALTLDGWIAIGVLAVMLVVAVWVMIAKAVYVNLVDAANQSFLEKFRELSSDLGALDKSTQMADAFRHS
SLYRLYHIAAQELSHRFKDTDASHLAEHDKNLTPQALDSIRASLDTGMVRESGLLTRLMVLLTIAISGGPFIGLLGTVLG
VMITFAVIAATGDVNVNAIAPGIAAALMATAAGMAVAIPALFGYNYLNSRIKTITSDMRVFIDELVTKLAENYSR

Sequences:

>Translated_555_residues
MHVLAVAIALLLSLFSAASHAWWNEDWSARKKITLTNPAGEIVDAPVLIRLHTGNFDFLSANEDGSDLRVVGGDDATELK
FHIEKWDGLNQLALVWVKMPKLAATTEAWLYFGNPEAAASSDAKGTYDAGSAVFHFNEAGGNPTDSAPAGANATAFTGTR
IAASFANGGAKFDATQILTLPALPVAGGWSASMWLKPAALDGALMQAGGYSAALTGGVLNVQAGAATVAAAVPLEVGKWQ
HVAVVVEGGTLRLYVAGKPAGEAAGAALPAGPLTVGSGYNGEADEIQLAGAARSAAWIAVAAAQGPDGTLVALGEDESSE
GGGGGIWATLFRALTLDGWIAIGVLAVMLVVAVWVMIAKAVYVNLVDAANQSFLEKFRELSSDLGALDKSTQMADAFRHS
SLYRLYHIAAQELSHRFKDTDASHLAEHDKNLTPQALDSIRASLDTGMVRESGLLTRLMVLLTIAISGGPFIGLLGTVLG
VMITFAVIAATGDVNVNAIAPGIAAALMATAAGMAVAIPALFGYNYLNSRIKTITSDMRVFIDELVTKLAENYSR
>Mature_555_residues
MHVLAVAIALLLSLFSAASHAWWNEDWSARKKITLTNPAGEIVDAPVLIRLHTGNFDFLSANEDGSDLRVVGGDDATELK
FHIEKWDGLNQLALVWVKMPKLAATTEAWLYFGNPEAAASSDAKGTYDAGSAVFHFNEAGGNPTDSAPAGANATAFTGTR
IAASFANGGAKFDATQILTLPALPVAGGWSASMWLKPAALDGALMQAGGYSAALTGGVLNVQAGAATVAAAVPLEVGKWQ
HVAVVVEGGTLRLYVAGKPAGEAAGAALPAGPLTVGSGYNGEADEIQLAGAARSAAWIAVAAAQGPDGTLVALGEDESSE
GGGGGIWATLFRALTLDGWIAIGVLAVMLVVAVWVMIAKAVYVNLVDAANQSFLEKFRELSSDLGALDKSTQMADAFRHS
SLYRLYHIAAQELSHRFKDTDASHLAEHDKNLTPQALDSIRASLDTGMVRESGLLTRLMVLLTIAISGGPFIGLLGTVLG
VMITFAVIAATGDVNVNAIAPGIAAALMATAAGMAVAIPALFGYNYLNSRIKTITSDMRVFIDELVTKLAENYSR

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=79, Percent_Identity=43.0379746835443, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1789381, Length=159, Percent_Identity=35.2201257861635, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 57588; Mature: 57588

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVLAVAIALLLSLFSAASHAWWNEDWSARKKITLTNPAGEIVDAPVLIRLHTGNFDFLS
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCEEEEE
ANEDGSDLRVVGGDDATELKFHIEKWDGLNQLALVWVKMPKLAATTEAWLYFGNPEAAAS
CCCCCCCEEEECCCCCCEEEEEEECCCCCCCEEEEEEECCCHHCCCEEEEEECCCCCCCC
SDAKGTYDAGSAVFHFNEAGGNPTDSAPAGANATAFTGTRIAASFANGGAKFDATQILTL
CCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEECCHHHEEHHCCCCCCCCCEEEEEE
PALPVAGGWSASMWLKPAALDGALMQAGGYSAALTGGVLNVQAGAATVAAAVPLEVGKWQ
CCCCCCCCCCCCCEECCHHHCCHHHHCCCCCCEECCCEEEEECCCHHHHEECCCCCCCCE
HVAVVVEGGTLRLYVAGKPAGEAAGAALPAGPLTVGSGYNGEADEIQLAGAARSAAWIAV
EEEEEEECCEEEEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCEEEEECCCCCCEEEEE
AAAQGPDGTLVALGEDESSEGGGGGIWATLFRALTLDGWIAIGVLAVMLVVAVWVMIAKA
EECCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
VYVNLVDAANQSFLEKFRELSSDLGALDKSTQMADAFRHSSLYRLYHIAAQELSHRFKDT
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DASHLAEHDKNLTPQALDSIRASLDTGMVRESGLLTRLMVLLTIAISGGPFIGLLGTVLG
CHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
VMITFAVIAATGDVNVNAIAPGIAAALMATAAGMAVAIPALFGYNYLNSRIKTITSDMRV
HHHHHHHHHCCCCCCEEEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIDELVTKLAENYSR
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MHVLAVAIALLLSLFSAASHAWWNEDWSARKKITLTNPAGEIVDAPVLIRLHTGNFDFLS
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCEEEEE
ANEDGSDLRVVGGDDATELKFHIEKWDGLNQLALVWVKMPKLAATTEAWLYFGNPEAAAS
CCCCCCCEEEECCCCCCEEEEEEECCCCCCCEEEEEEECCCHHCCCEEEEEECCCCCCCC
SDAKGTYDAGSAVFHFNEAGGNPTDSAPAGANATAFTGTRIAASFANGGAKFDATQILTL
CCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEECCHHHEEHHCCCCCCCCCEEEEEE
PALPVAGGWSASMWLKPAALDGALMQAGGYSAALTGGVLNVQAGAATVAAAVPLEVGKWQ
CCCCCCCCCCCCCEECCHHHCCHHHHCCCCCCEECCCEEEEECCCHHHHEECCCCCCCCE
HVAVVVEGGTLRLYVAGKPAGEAAGAALPAGPLTVGSGYNGEADEIQLAGAARSAAWIAV
EEEEEEECCEEEEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCEEEEECCCCCCEEEEE
AAAQGPDGTLVALGEDESSEGGGGGIWATLFRALTLDGWIAIGVLAVMLVVAVWVMIAKA
EECCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
VYVNLVDAANQSFLEKFRELSSDLGALDKSTQMADAFRHSSLYRLYHIAAQELSHRFKDT
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DASHLAEHDKNLTPQALDSIRASLDTGMVRESGLLTRLMVLLTIAISGGPFIGLLGTVLG
CHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
VMITFAVIAATGDVNVNAIAPGIAAALMATAAGMAVAIPALFGYNYLNSRIKTITSDMRV
HHHHHHHHHCCCCCCEEEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIDELVTKLAENYSR
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 8921895 [H]