Click here to switch to the map view.

The map label for this gene is wza [H]

Identifier: 74316299

GI number: 74316299

Start: 298185

End: 298808

Strand: Direct

Name: wza [H]

Synonym: Tbd_0281

Alternate gene names: 74316299

Gene position: 298185-298808 (Clockwise)

Preceding gene: 74316292

Following gene: 74316300

Centisome position: 10.25

GC content: 64.9

Gene sequence:

>624_bases
ATGATCACGATCAAAAAGCACCTCTCGCGCGCGAGCCTGCTGCTCGCAGTGGTCGCCGTCGCGGGATGCTCGGGTACGCC
GACATACCCGCCTGCGCCCGAGCGCACCGGGCAGTACGACTGGAATTACCTGGTCGGCCCGGGCGATTCGGTCAACGTCT
TCGTATGGCGCAACCCCGAAGTCTCGGGCACCTTCCCGGTGCGTCCAGACGGCAAAATGACCATGAACCTCGTCGAGGAT
CTGCAGGCGTCCGGCAAGACGCCGACGCAGCTCGCGCGGGACATCGAAAAGGCGCTCGGCAAGTACATCCAGGAACCGAT
CGTCACTGTCATCGTCGGCGGCGGCATCGGGCCGTTCGACCAGCAGATCCGCGTGGTCGGCGAAGCCGCCAAGCCCCAGG
CGCTCAATTACCGCGAGAAGATGAGCCTCGTCGACCTCATGATCGCGGTCGGCGGACTCACCGATTTCGCTGCCGGCAAC
AAGGCCTACATCCTCCGCACCGTCGACGGCAAGCAGGAGCGCCTCGGCGTCCGTCTCGAAGATCTGCTGCGCGGCGGCGA
CGTCTCCGCAAACGTCGACATGCGCCCCGGCGATGTCCTCGTCGTGCCTGAAAGCCTGTTCTAA

Upstream 100 bases:

>100_bases
CTGGTCCGTGGTTTGCTAGCAGCCTCTTCCACAAACACCAGTTTTTTTTAATTCGCTGGTGCATAATGCCGGCGAATTAA
TACCTACAACGGGGATGGAG

Downstream 100 bases:

>100_bases
ACGTGTCCGCGCCGCTCGCGCGGCGCTCGTGCCCGAGCCCACGCTGGCCGGCGCTTTTTGATGGCTGAGGGTCCTGCGTA
TGGATCAAGTTTTGCAGCAA

Product: polysaccharide export outer membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MITIKKHLSRASLLLAVVAVAGCSGTPTYPPAPERTGQYDWNYLVGPGDSVNVFVWRNPEVSGTFPVRPDGKMTMNLVED
LQASGKTPTQLARDIEKALGKYIQEPIVTVIVGGGIGPFDQQIRVVGEAAKPQALNYREKMSLVDLMIAVGGLTDFAAGN
KAYILRTVDGKQERLGVRLEDLLRGGDVSANVDMRPGDVLVVPESLF

Sequences:

>Translated_207_residues
MITIKKHLSRASLLLAVVAVAGCSGTPTYPPAPERTGQYDWNYLVGPGDSVNVFVWRNPEVSGTFPVRPDGKMTMNLVED
LQASGKTPTQLARDIEKALGKYIQEPIVTVIVGGGIGPFDQQIRVVGEAAKPQALNYREKMSLVDLMIAVGGLTDFAAGN
KAYILRTVDGKQERLGVRLEDLLRGGDVSANVDMRPGDVLVVPESLF
>Mature_207_residues
MITIKKHLSRASLLLAVVAVAGCSGTPTYPPAPERTGQYDWNYLVGPGDSVNVFVWRNPEVSGTFPVRPDGKMTMNLVED
LQASGKTPTQLARDIEKALGKYIQEPIVTVIVGGGIGPFDQQIRVVGEAAKPQALNYREKMSLVDLMIAVGGLTDFAAGN
KAYILRTVDGKQERLGVRLEDLLRGGDVSANVDMRPGDVLVVPESLF

Specific function: Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium [H]

COG id: COG1596

COG function: function code M; Periplasmic protein involved in polysaccharide export

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BexD/CtrA/VexA family [H]

Homologues:

Organism=Escherichia coli, GI1788376, Length=180, Percent_Identity=32.7777777777778, Blast_Score=78, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003715
- InterPro:   IPR019554 [H]

Pfam domain/function: PF02563 Poly_export; PF10531 SLBB [H]

EC number: NA

Molecular weight: Translated: 22322; Mature: 22322

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIKKHLSRASLLLAVVAVAGCSGTPTYPPAPERTGQYDWNYLVGPGDSVNVFVWRNPE
CEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEECCC
VSGTFPVRPDGKMTMNLVEDLQASGKTPTQLARDIEKALGKYIQEPIVTVIVGGGIGPFD
CCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHH
QQIRVVGEAAKPQALNYREKMSLVDLMIAVGGLTDFAAGNKAYILRTVDGKQERLGVRLE
HHHHEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCCEEEEEEECCCCHHHHCCCHH
DLLRGGDVSANVDMRPGDVLVVPESLF
HHHCCCCCCCCCCCCCCCEEEECCCCC
>Mature Secondary Structure
MITIKKHLSRASLLLAVVAVAGCSGTPTYPPAPERTGQYDWNYLVGPGDSVNVFVWRNPE
CEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEECCC
VSGTFPVRPDGKMTMNLVEDLQASGKTPTQLARDIEKALGKYIQEPIVTVIVGGGIGPFD
CCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHH
QQIRVVGEAAKPQALNYREKMSLVDLMIAVGGLTDFAAGNKAYILRTVDGKQERLGVRLE
HHHHEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCCEEEEEEECCCCHHHHCCCHH
DLLRGGDVSANVDMRPGDVLVVPESLF
HHHCCCCCCCCCCCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]