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The map label for this gene is cbbT [H]

Identifier: 74316177

GI number: 74316177

Start: 170335

End: 172320

Strand: Direct

Name: cbbT [H]

Synonym: Tbd_0159

Alternate gene names: 74316177

Gene position: 170335-172320 (Clockwise)

Preceding gene: 74316176

Following gene: 74316178

Centisome position: 5.85

GC content: 65.91

Gene sequence:

>1986_bases
ATGCCAACCCGTACCGACCTGTCGAACGCCATCCGCGCACTCGCGATGGATGCAGTCGAAAAAGCGAAATCCGGCCACCC
CGGCGCCCCGATGGGCATGGCGGAAATCGCCGAGACGCTGTGGAACCATCATATGCGTCACAACCCGGTCAACCCCAAGT
GGGCCGACCGTGACCGCTTCGTGCTGTCGAACGGTCACGGCTCGATGCTGATCTATGCGCTGTTGCACCTGACCGGTTAC
GACCTGTCGATGGACGACCTCAAGCAGTTCCGCCAGTTGCACTCGAAGACCCCGGGCCACCCCGAGTACGGCTATGCGCC
CGGCGTCGAGACGACGACCGGCCCGCTCGGCCAGGGCATCACCAACGCGGTCGGCATGGCGATGGCGGAAAAAGTGCTGG
CGCACGAATTCAATAAGCCCGGCCACAGCATCGTCGACCACCACACCTACGTGTTCCTCGGCGACGGCTGCATGATGGAA
GGCATCTCGCACGAGGCCTGCGCGCTCGCCGGCACCTGGAAGCTCAACAAGCTGATCGCGTTCTGGGACGACAACGGCAT
TTCGATCGACGGCCACATCGAGCACTGGTACACCGACGACACGGCCAAGCGTTTCGAAGCCTACGGCTGGCAGGTCATCC
CGAACGTCGACGGCCACGACGTCGTCGCGATCGAAGCCGCGATCCAGAAGGCCAAGGCGAGCAGCGACAAGCCCACGCTG
ATCTGCTGCAAGACGATCATCGGCAAGGGCTCGCCGAACAAGGCCGGTACGCACGACGTGCACGGCGCAGCGCTCGGCCA
CGACGAAGTCGAGGCGACCCGCAAGAACATGGGCTGGAATTCGCCGGCGTTCGAAGTGCCGGCCGACATCTACGCCGGCT
GGGACGCGAAGACCAAGGGCCAGGGGCTCGAGACGCTGTGGAACAACAAGTTCGCCGAGTACAAGAAGGCCTTCCCCGCC
GAAGCCGCCGAATTCGAGCGCCGCATGAAGGGCGAACTGCCCGCCAACTGGAAGGCGCACGTCGCCGAGAAGCTGGCTGC
GATCAACGCCAAGGGCGAGACCGTCGCCACGCGCAAGGCCAGCCAGATCGCGATCAACGCGCTGGCTTCCGCGCTGCCGG
AGTTCCTCGGCGGTTCGGCCGACCTGACCGGCTCCAACCTGACCAACTGGGAAGGCTGCCACCCGGTGCGCCACGGCAAG
CCCGGCAACTACATCAGCTACGGCGTGCGTGAATTCGGCATGGCCGCGATCATGAACGGCATGGCGCTGCACGGCGGCCT
CTTGCCCTTCGGCGGCACCTTCCTGATGTTCTCCGAATACTCGCGCAACGCCATCCGCATGGCCGCGCTGATGAAGCAGC
GCGTGATCCACGTGTTTACGCACGATTCGATCGGTCTCGGCGAAGACGGCCCGACCCACCAGCCTGTCGAGCAGACCGCG
ACCCTGCGCATGATCCCCAACATCGACGTCTGGCGTCCGTGCGACACCGTCGAGACCATGGTCGGCTGGGCGCACTCGGT
CGAGCGCACCGACGGCCCGACCTGCCACATCCTCTCGCGCCAGAACCTGCCGTTCATGCAGCGCGACGACGCGACGCTCG
CGAGCATCGCAAAGGGCGGCTATGTGCTGAAGGATGCGGCCGGCGCGAAGGCCGTCATCATCGCCACCGGCTCCGAAGTC
GAACTCGCGGTGAAGGCCGCTGACACGCTCGCCGCCGAAGGCATCGCGGTGCGCGTCGTCTCGATGCCGTCGACCAACAC
CTTCGACCGCCAGGACGCCGCCTACCGCGAAAGCGTGCTGCCGAAGGGCCTGCCGCGCGTCGCCGTCGAAGCCGGCGTCA
CCGACTTCTGGCGCAAGTACGTGGGTCTCGAAGGCGCCGTGGTCGGCATCGACACCTTCGGCGAATCGGCCCCTGCGCCC
GCGCTGTTCAAGCATTTCGGCATCACCGCCGAGGCCGTCGCGGCCGCGGTCAAGAGCGTGCTGTAA

Upstream 100 bases:

>100_bases
GTGACGGATAATCAGCGTTTTTGCATATTCTGCCCAAGCTGTCGCCGCACGGCTGTTCCGGGCGAGGGTGCGAGATTTTT
TTCTTAGCGAAGGGACCGCA

Downstream 100 bases:

>100_bases
CTACGAGGGGTCAGGATTCAGGGATCAGGATTCAGGGGATGAGCGGGCTGCGCCCGCGTCAGAGACGACGCGGCCTTCGG
CCGCTCACTCCCTGACCCCT

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 661; Mature: 660

Protein sequence:

>661_residues
MPTRTDLSNAIRALAMDAVEKAKSGHPGAPMGMAEIAETLWNHHMRHNPVNPKWADRDRFVLSNGHGSMLIYALLHLTGY
DLSMDDLKQFRQLHSKTPGHPEYGYAPGVETTTGPLGQGITNAVGMAMAEKVLAHEFNKPGHSIVDHHTYVFLGDGCMME
GISHEACALAGTWKLNKLIAFWDDNGISIDGHIEHWYTDDTAKRFEAYGWQVIPNVDGHDVVAIEAAIQKAKASSDKPTL
ICCKTIIGKGSPNKAGTHDVHGAALGHDEVEATRKNMGWNSPAFEVPADIYAGWDAKTKGQGLETLWNNKFAEYKKAFPA
EAAEFERRMKGELPANWKAHVAEKLAAINAKGETVATRKASQIAINALASALPEFLGGSADLTGSNLTNWEGCHPVRHGK
PGNYISYGVREFGMAAIMNGMALHGGLLPFGGTFLMFSEYSRNAIRMAALMKQRVIHVFTHDSIGLGEDGPTHQPVEQTA
TLRMIPNIDVWRPCDTVETMVGWAHSVERTDGPTCHILSRQNLPFMQRDDATLASIAKGGYVLKDAAGAKAVIIATGSEV
ELAVKAADTLAAEGIAVRVVSMPSTNTFDRQDAAYRESVLPKGLPRVAVEAGVTDFWRKYVGLEGAVVGIDTFGESAPAP
ALFKHFGITAEAVAAAVKSVL

Sequences:

>Translated_661_residues
MPTRTDLSNAIRALAMDAVEKAKSGHPGAPMGMAEIAETLWNHHMRHNPVNPKWADRDRFVLSNGHGSMLIYALLHLTGY
DLSMDDLKQFRQLHSKTPGHPEYGYAPGVETTTGPLGQGITNAVGMAMAEKVLAHEFNKPGHSIVDHHTYVFLGDGCMME
GISHEACALAGTWKLNKLIAFWDDNGISIDGHIEHWYTDDTAKRFEAYGWQVIPNVDGHDVVAIEAAIQKAKASSDKPTL
ICCKTIIGKGSPNKAGTHDVHGAALGHDEVEATRKNMGWNSPAFEVPADIYAGWDAKTKGQGLETLWNNKFAEYKKAFPA
EAAEFERRMKGELPANWKAHVAEKLAAINAKGETVATRKASQIAINALASALPEFLGGSADLTGSNLTNWEGCHPVRHGK
PGNYISYGVREFGMAAIMNGMALHGGLLPFGGTFLMFSEYSRNAIRMAALMKQRVIHVFTHDSIGLGEDGPTHQPVEQTA
TLRMIPNIDVWRPCDTVETMVGWAHSVERTDGPTCHILSRQNLPFMQRDDATLASIAKGGYVLKDAAGAKAVIIATGSEV
ELAVKAADTLAAEGIAVRVVSMPSTNTFDRQDAAYRESVLPKGLPRVAVEAGVTDFWRKYVGLEGAVVGIDTFGESAPAP
ALFKHFGITAEAVAAAVKSVL
>Mature_660_residues
PTRTDLSNAIRALAMDAVEKAKSGHPGAPMGMAEIAETLWNHHMRHNPVNPKWADRDRFVLSNGHGSMLIYALLHLTGYD
LSMDDLKQFRQLHSKTPGHPEYGYAPGVETTTGPLGQGITNAVGMAMAEKVLAHEFNKPGHSIVDHHTYVFLGDGCMMEG
ISHEACALAGTWKLNKLIAFWDDNGISIDGHIEHWYTDDTAKRFEAYGWQVIPNVDGHDVVAIEAAIQKAKASSDKPTLI
CCKTIIGKGSPNKAGTHDVHGAALGHDEVEATRKNMGWNSPAFEVPADIYAGWDAKTKGQGLETLWNNKFAEYKKAFPAE
AAEFERRMKGELPANWKAHVAEKLAAINAKGETVATRKASQIAINALASALPEFLGGSADLTGSNLTNWEGCHPVRHGKP
GNYISYGVREFGMAAIMNGMALHGGLLPFGGTFLMFSEYSRNAIRMAALMKQRVIHVFTHDSIGLGEDGPTHQPVEQTAT
LRMIPNIDVWRPCDTVETMVGWAHSVERTDGPTCHILSRQNLPFMQRDDATLASIAKGGYVLKDAAGAKAVIIATGSEVE
LAVKAADTLAAEGIAVRVVSMPSTNTFDRQDAAYRESVLPKGLPRVAVEAGVTDFWRKYVGLEGAVVGIDTFGESAPAPA
LFKHFGITAEAVAAAVKSVL

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=673, Percent_Identity=28.8261515601783, Blast_Score=188, Evalue=2e-47,
Organism=Homo sapiens, GI4507521, Length=673, Percent_Identity=28.8261515601783, Blast_Score=188, Evalue=2e-47,
Organism=Homo sapiens, GI133778974, Length=588, Percent_Identity=26.8707482993197, Blast_Score=167, Evalue=4e-41,
Organism=Homo sapiens, GI225637459, Length=606, Percent_Identity=23.5973597359736, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI225637461, Length=577, Percent_Identity=23.5701906412478, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI225637463, Length=528, Percent_Identity=23.6742424242424, Blast_Score=109, Evalue=9e-24,
Organism=Escherichia coli, GI48994911, Length=663, Percent_Identity=67.5716440422323, Blast_Score=949, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=661, Percent_Identity=62.3298033282905, Blast_Score=862, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=678, Percent_Identity=28.1710914454277, Blast_Score=188, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6325331, Length=657, Percent_Identity=52.20700152207, Blast_Score=643, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319593, Length=665, Percent_Identity=46.015037593985, Blast_Score=580, Evalue=1e-166,
Organism=Drosophila melanogaster, GI45551847, Length=686, Percent_Identity=27.1137026239067, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI45550715, Length=686, Percent_Identity=27.1137026239067, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24645119, Length=652, Percent_Identity=25.920245398773, Blast_Score=159, Evalue=6e-39,
Organism=Drosophila melanogaster, GI24666278, Length=677, Percent_Identity=24.6676514032496, Blast_Score=153, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 71385; Mature: 71254

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTRTDLSNAIRALAMDAVEKAKSGHPGAPMGMAEIAETLWNHHMRHNPVNPKWADRDRF
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCE
VLSNGHGSMLIYALLHLTGYDLSMDDLKQFRQLHSKTPGHPEYGYAPGVETTTGPLGQGI
EEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
TNAVGMAMAEKVLAHEFNKPGHSIVDHHTYVFLGDGCMMEGISHEACALAGTWKLNKLIA
HHHHHHHHHHHHHHHHCCCCCCCHHCCCEEEEECCCHHCCCCCCCHHEEECCEEECEEEE
FWDDNGISIDGHIEHWYTDDTAKRFEAYGWQVIPNVDGHDVVAIEAAIQKAKASSDKPTL
EECCCCEEECCCEEEEECCHHHHHHHHCCCEEECCCCCCCEEEHHHHHHHHHCCCCCCEE
ICCKTIIGKGSPNKAGTHDVHGAALGHDEVEATRKNMGWNSPAFEVPADIYAGWDAKTKG
EEEHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCC
QGLETLWNNKFAEYKKAFPAEAAEFERRMKGELPANWKAHVAEKLAAINAKGETVATRKA
CCHHHHHCCHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
SQIAINALASALPEFLGGSADLTGSNLTNWEGCHPVRHGKPGNYISYGVREFGMAAIMNG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
MALHGGLLPFGGTFLMFSEYSRNAIRMAALMKQRVIHVFTHDSIGLGEDGPTHQPVEQTA
HHHCCCCCCCCCEEEEEEHHCCHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCHHHCE
TLRMIPNIDVWRPCDTVETMVGWAHSVERTDGPTCHILSRQNLPFMQRDDATLASIAKGG
EEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHCCC
YVLKDAAGAKAVIIATGSEVELAVKAADTLAAEGIAVRVVSMPSTNTFDRQDAAYRESVL
EEEEECCCCCEEEEEECCCEEEEEEHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHC
PKGLPRVAVEAGVTDFWRKYVGLEGAVVGIDTFGESAPAPALFKHFGITAEAVAAAVKSV
CCCCCHHHHHHCHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHC
L
C
>Mature Secondary Structure 
PTRTDLSNAIRALAMDAVEKAKSGHPGAPMGMAEIAETLWNHHMRHNPVNPKWADRDRF
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCE
VLSNGHGSMLIYALLHLTGYDLSMDDLKQFRQLHSKTPGHPEYGYAPGVETTTGPLGQGI
EEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
TNAVGMAMAEKVLAHEFNKPGHSIVDHHTYVFLGDGCMMEGISHEACALAGTWKLNKLIA
HHHHHHHHHHHHHHHHCCCCCCCHHCCCEEEEECCCHHCCCCCCCHHEEECCEEECEEEE
FWDDNGISIDGHIEHWYTDDTAKRFEAYGWQVIPNVDGHDVVAIEAAIQKAKASSDKPTL
EECCCCEEECCCEEEEECCHHHHHHHHCCCEEECCCCCCCEEEHHHHHHHHHCCCCCCEE
ICCKTIIGKGSPNKAGTHDVHGAALGHDEVEATRKNMGWNSPAFEVPADIYAGWDAKTKG
EEEHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCC
QGLETLWNNKFAEYKKAFPAEAAEFERRMKGELPANWKAHVAEKLAAINAKGETVATRKA
CCHHHHHCCHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
SQIAINALASALPEFLGGSADLTGSNLTNWEGCHPVRHGKPGNYISYGVREFGMAAIMNG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
MALHGGLLPFGGTFLMFSEYSRNAIRMAALMKQRVIHVFTHDSIGLGEDGPTHQPVEQTA
HHHCCCCCCCCCEEEEEEHHCCHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCHHHCE
TLRMIPNIDVWRPCDTVETMVGWAHSVERTDGPTCHILSRQNLPFMQRDDATLASIAKGG
EEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHCCC
YVLKDAAGAKAVIIATGSEVELAVKAADTLAAEGIAVRVVSMPSTNTFDRQDAAYRESVL
EEEEECCCCCEEEEEECCCEEEEEEHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHC
PKGLPRVAVEAGVTDFWRKYVGLEGAVVGIDTFGESAPAPALFKHFGITAEAVAAAVKSV
CCCCCHHHHHHCHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]