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The map label for this gene is suhB [H]

Identifier: 74316176

GI number: 74316176

Start: 169297

End: 170103

Strand: Direct

Name: suhB [H]

Synonym: Tbd_0158

Alternate gene names: 74316176

Gene position: 169297-170103 (Clockwise)

Preceding gene: 74316175

Following gene: 74316177

Centisome position: 5.82

GC content: 68.77

Gene sequence:

>807_bases
TTGCTACTGCCGGCGCGTCTGAACATGCTGGAAGAGGTCAAGGCCCTGGTGCGCGAAGTCGCGCAGCGTGAGGTGACGCC
GCGCTTTCTCAAGGTCGCGCACAGCCACAAAGCCGACGGCAGCCTTTTCACCGAGGCCGATGCGCTCGCGCAGGCTGCGC
TCGAAGTGGGGCTGCCGCGAATCCGCGACGTGCCCGTGCTCGGCGAGGAAATGACCGAGCGCGAGCAGCAGGACGCGTGG
GGCGCGGGACGCGAGGGACTGTGGTGCGTCGACCCGATCGACGGCACCTCCAACTTCGTCGCCGGCGTGCCCTACTTCGC
GATCTCGGTGGCCTATCTCTACAAGGGCGAGCGCCAGCTCGGGGTCGTCTACGACCCGATCGCCGATGAGATGTTCAGCG
CCGTACGCGGCCAGGGCGCGCATCTGAACGGCACGCCGCTGCCCTTGCGCCCGCCCGTGCAGGATCTGCGCCGCGCGCTG
GCCGGCGTCGAGATGAAACGCATCGACCGTGAACTGGCGGGGCGGCTCGCCTCGTGGCCGCCCTACGCGTCGCAGCGCAA
CTTCGGCGCGTCGACGCTCGACTGGTGTTACACGGCGGCGGGCCGCTTCGACATCTATGTCCACGGCGGGCAAAAGCTCT
GGGATTACGCTGCCGGCGCGCTGATCCTCGAAGAGGCCGGCGGCCGCCTCGCCAGCCTGACCGGCAGCTTCGACATTGCG
AGCGTGTGGGAGCGCTCGGTCGTCGCCTCGGTGAGTCCGGACTTGTTCGAGCAGTGGCGAGACTGGCTCAAGGCGGCGGG
CGCATAA

Upstream 100 bases:

>100_bases
CGCAGTCGCTGCATGCCGAGTTCGGTGCACCCTTCCAGCTGCTCGGCCATGAAACGGAGATCCACCACACTCCCACGGGG
CGTGACCAGGAATTCGTTTA

Downstream 100 bases:

>100_bases
GCGACCGCACAGCCGGAATAAAAAGATTTTAACCGCCGCTTATTGAATTCCCACCTTAGCTTCGGGGGTTAAGCCCTTGT
CCGCGCAAGGCTTTCGCGCT

Product: myo-inositol-1(or 4)-monophosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MLLPARLNMLEEVKALVREVAQREVTPRFLKVAHSHKADGSLFTEADALAQAALEVGLPRIRDVPVLGEEMTEREQQDAW
GAGREGLWCVDPIDGTSNFVAGVPYFAISVAYLYKGERQLGVVYDPIADEMFSAVRGQGAHLNGTPLPLRPPVQDLRRAL
AGVEMKRIDRELAGRLASWPPYASQRNFGASTLDWCYTAAGRFDIYVHGGQKLWDYAAGALILEEAGGRLASLTGSFDIA
SVWERSVVASVSPDLFEQWRDWLKAAGA

Sequences:

>Translated_268_residues
MLLPARLNMLEEVKALVREVAQREVTPRFLKVAHSHKADGSLFTEADALAQAALEVGLPRIRDVPVLGEEMTEREQQDAW
GAGREGLWCVDPIDGTSNFVAGVPYFAISVAYLYKGERQLGVVYDPIADEMFSAVRGQGAHLNGTPLPLRPPVQDLRRAL
AGVEMKRIDRELAGRLASWPPYASQRNFGASTLDWCYTAAGRFDIYVHGGQKLWDYAAGALILEEAGGRLASLTGSFDIA
SVWERSVVASVSPDLFEQWRDWLKAAGA
>Mature_268_residues
MLLPARLNMLEEVKALVREVAQREVTPRFLKVAHSHKADGSLFTEADALAQAALEVGLPRIRDVPVLGEEMTEREQQDAW
GAGREGLWCVDPIDGTSNFVAGVPYFAISVAYLYKGERQLGVVYDPIADEMFSAVRGQGAHLNGTPLPLRPPVQDLRRAL
AGVEMKRIDRELAGRLASWPPYASQRNFGASTLDWCYTAAGRFDIYVHGGQKLWDYAAGALILEEAGGRLASLTGSFDIA
SVWERSVVASVSPDLFEQWRDWLKAAGA

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=179, Percent_Identity=32.4022346368715, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI221625487, Length=179, Percent_Identity=32.4022346368715, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI7657236, Length=155, Percent_Identity=34.8387096774194, Blast_Score=88, Evalue=6e-18,
Organism=Escherichia coli, GI1788882, Length=218, Percent_Identity=34.4036697247706, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1790659, Length=188, Percent_Identity=31.3829787234043, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193202572, Length=227, Percent_Identity=30.3964757709251, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI193202570, Length=240, Percent_Identity=31.25, Blast_Score=94, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6320493, Length=241, Percent_Identity=27.8008298755187, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6321836, Length=157, Percent_Identity=29.2993630573248, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24664922, Length=210, Percent_Identity=35.7142857142857, Blast_Score=120, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24664926, Length=238, Percent_Identity=36.1344537815126, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21357303, Length=183, Percent_Identity=33.879781420765, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI21357329, Length=236, Percent_Identity=31.7796610169492, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI21357957, Length=201, Percent_Identity=29.3532338308458, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24664918, Length=238, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550
- InterPro:   IPR022337 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 29442; Mature: 29442

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLPARLNMLEEVKALVREVAQREVTPRFLKVAHSHKADGSLFTEADALAQAALEVGLPR
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
IRDVPVLGEEMTEREQQDAWGAGREGLWCVDPIDGTSNFVAGVPYFAISVAYLYKGERQL
CCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHCCHHHHHHHHHHHCCCCCC
GVVYDPIADEMFSAVRGQGAHLNGTPLPLRPPVQDLRRALAGVEMKRIDRELAGRLASWP
CEEECHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCC
PYASQRNFGASTLDWCYTAAGRFDIYVHGGQKLWDYAAGALILEEAGGRLASLTGSFDIA
CCCCCCCCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCEEECCCCCHHH
SVWERSVVASVSPDLFEQWRDWLKAAGA
HHHHHHHHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLLPARLNMLEEVKALVREVAQREVTPRFLKVAHSHKADGSLFTEADALAQAALEVGLPR
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
IRDVPVLGEEMTEREQQDAWGAGREGLWCVDPIDGTSNFVAGVPYFAISVAYLYKGERQL
CCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHCCHHHHHHHHHHHCCCCCC
GVVYDPIADEMFSAVRGQGAHLNGTPLPLRPPVQDLRRALAGVEMKRIDRELAGRLASWP
CEEECHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCC
PYASQRNFGASTLDWCYTAAGRFDIYVHGGQKLWDYAAGALILEEAGGRLASLTGSFDIA
CCCCCCCCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCEEECCCCCHHH
SVWERSVVASVSPDLFEQWRDWLKAAGA
HHHHHHHHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]