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The map label for this gene is rocF [H]

Identifier: 74316087

GI number: 74316087

Start: 71231

End: 72136

Strand: Reverse

Name: rocF [H]

Synonym: Tbd_0069

Alternate gene names: 74316087

Gene position: 72136-71231 (Counterclockwise)

Preceding gene: 74316088

Following gene: 74316085

Centisome position: 2.48

GC content: 72.85

Gene sequence:

>906_bases
ATGTCAGAGCCCAAGCCCGAGCGCAGCATCATCGTGATCGGCGCCGCGAGTTGCGCCGGCGCACCCGACCCGGGCTGCGC
CGCCGGGCCCGACGCCCTACATCATTACGAGGTGTTCCACGACACCCCGCTGCAACGCGTCGCCTGGGACGCGATCCTGC
GCGTGCCGCGCATGCCGCCGCAGGCAGCCCTGATCGCGGTCTCCGCACTCAACCGCAAGCTCGCGGAAAAGGTCCATGGC
GTGCTCGACGAGGGCAATTTCCCGCTCGTCGTCGGCGGCGACCACTCGTGCGCGATCGGCACATGGAGCGGCGCCCAGCG
CGCGCTCGCCGACCGCGGCGCGCTCGGACTGATCTGGATCGACGCGCACATGGACAGTCACACCTTCGATACGACGCAGA
GCGGCCAACTCCACGGCATGCCGGTCGCAAGCCTGCTCGGCCGCGGCCATGCGGCGCTGCGCGCCTTCGGCCCGCCGCTG
CCCGACCTGCGTCCGGGCGACCTGTGCCTGATCGGCGTGCGCAGCTACGAGGCCGGCGAGGCGGCGCTGCTGCATCAACT
CGGCGTGCGCGTCTACACGATGGACGAAGTGCGCGCGCGTGGCCTTCGCGCCGTGTTCGACGAGGCGCTGGCGCGGGTGC
GTGCCCGCACCGCCGGCTTCGGCGTCAGCGTCGACCTCGACGCGCTCGACCCCGAGGAGGAGCCGGGCGTCGGCTCGCCG
GTGCCGGGCGGGATCCGCTGCGCCGAACTCGCCGCGGCGCTCGCGCGGCTGCGCGGCGACCCCGACTTCATCGCGATGGA
AATCGTCGAATACAACCCCTACCGCGACCGCGACCGCGCGACGGCGGACGCCGCAGGCGCCTTCGTCGAAGCGGTGACGC
CGCTCGCGTCGAAGCCGGCGCGCTGA

Upstream 100 bases:

>100_bases
CGTCTACAACAAGACGACACGCTCGGCCGGCACGAGCCACTGAGCGACGGCGCCGTCGCGTTCGCTCGCCCGCCTGGCGG
CCCACCTGCTAGGCTGAAGC

Downstream 100 bases:

>100_bases
ACTGCCGGCGGAAACGCGGCGCTCAGCCGGCGGCGTCGCCGACGAAGGGGTTGTCGCGGCGCTCGTGACCGAAGCTCGAC
ATTGCGCCGTGACCCGGGAC

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MSEPKPERSIIVIGAASCAGAPDPGCAAGPDALHHYEVFHDTPLQRVAWDAILRVPRMPPQAALIAVSALNRKLAEKVHG
VLDEGNFPLVVGGDHSCAIGTWSGAQRALADRGALGLIWIDAHMDSHTFDTTQSGQLHGMPVASLLGRGHAALRAFGPPL
PDLRPGDLCLIGVRSYEAGEAALLHQLGVRVYTMDEVRARGLRAVFDEALARVRARTAGFGVSVDLDALDPEEEPGVGSP
VPGGIRCAELAAALARLRGDPDFIAMEIVEYNPYRDRDRATADAAGAFVEAVTPLASKPAR

Sequences:

>Translated_301_residues
MSEPKPERSIIVIGAASCAGAPDPGCAAGPDALHHYEVFHDTPLQRVAWDAILRVPRMPPQAALIAVSALNRKLAEKVHG
VLDEGNFPLVVGGDHSCAIGTWSGAQRALADRGALGLIWIDAHMDSHTFDTTQSGQLHGMPVASLLGRGHAALRAFGPPL
PDLRPGDLCLIGVRSYEAGEAALLHQLGVRVYTMDEVRARGLRAVFDEALARVRARTAGFGVSVDLDALDPEEEPGVGSP
VPGGIRCAELAAALARLRGDPDFIAMEIVEYNPYRDRDRATADAAGAFVEAVTPLASKPAR
>Mature_300_residues
SEPKPERSIIVIGAASCAGAPDPGCAAGPDALHHYEVFHDTPLQRVAWDAILRVPRMPPQAALIAVSALNRKLAEKVHGV
LDEGNFPLVVGGDHSCAIGTWSGAQRALADRGALGLIWIDAHMDSHTFDTTQSGQLHGMPVASLLGRGHAALRAFGPPLP
DLRPGDLCLIGVRSYEAGEAALLHQLGVRVYTMDEVRARGLRAVFDEALARVRARTAGFGVSVDLDALDPEEEPGVGSPV
PGGIRCAELAAALARLRGDPDFIAMEIVEYNPYRDRDRATADAAGAFVEAVTPLASKPAR

Specific function: Controls arginine catabolism [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI10947139, Length=283, Percent_Identity=32.5088339222615, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI4502215, Length=286, Percent_Identity=29.7202797202797, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71996843, Length=232, Percent_Identity=43.9655172413793, Blast_Score=196, Evalue=9e-51,
Organism=Saccharomyces cerevisiae, GI6325146, Length=218, Percent_Identity=36.697247706422, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24638886, Length=305, Percent_Identity=30.8196721311475, Blast_Score=114, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 31803; Mature: 31671

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPKPERSIIVIGAASCAGAPDPGCAAGPDALHHYEVFHDTPLQRVAWDAILRVPRMPP
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
QAALIAVSALNRKLAEKVHGVLDEGNFPLVVGGDHSCAIGTWSGAQRALADRGALGLIWI
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCHHHHHHCCCCEEEEEE
DAHMDSHTFDTTQSGQLHGMPVASLLGRGHAALRAFGPPLPDLRPGDLCLIGVRSYEAGE
EECCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHCCCCCCCCCCCCEEEEEECCCCCCH
AALLHQLGVRVYTMDEVRARGLRAVFDEALARVRARTAGFGVSVDLDALDPEEEPGVGSP
HHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCC
VPGGIRCAELAAALARLRGDPDFIAMEIVEYNPYRDRDRATADAAGAFVEAVTPLASKPA
CCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
R
C
>Mature Secondary Structure 
SEPKPERSIIVIGAASCAGAPDPGCAAGPDALHHYEVFHDTPLQRVAWDAILRVPRMPP
CCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
QAALIAVSALNRKLAEKVHGVLDEGNFPLVVGGDHSCAIGTWSGAQRALADRGALGLIWI
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCHHHHHHCCCCEEEEEE
DAHMDSHTFDTTQSGQLHGMPVASLLGRGHAALRAFGPPLPDLRPGDLCLIGVRSYEAGE
EECCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHCCCCCCCCCCCCEEEEEECCCCCCH
AALLHQLGVRVYTMDEVRARGLRAVFDEALARVRARTAGFGVSVDLDALDPEEEPGVGSP
HHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCC
VPGGIRCAELAAALARLRGDPDFIAMEIVEYNPYRDRDRATADAAGAFVEAVTPLASKPA
CCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8647285; 10196128 [H]