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The map label for this gene is nudG [C]

Identifier: 74316045

GI number: 74316045

Start: 27478

End: 28416

Strand: Reverse

Name: nudG [C]

Synonym: Tbd_0027

Alternate gene names: 74316045

Gene position: 28416-27478 (Counterclockwise)

Preceding gene: 74316046

Following gene: 74316044

Centisome position: 0.98

GC content: 71.25

Gene sequence:

>939_bases
ATGAACGCGGCCGTCGTCGAGGTCGTCGCCGCGGTCCTGACCCAGCCAGACGGCCGCGTGCTGCTCGCGCAACGCCCCGC
GGGCAAGGTATACGCCGGTCATTGGGAATTCCCGGGAGGCAAGGTCGAGGCGGGCGAAACGCTCGAAGACGCGCTCGTCC
GCGAACTGCGCGAGGAACTCGGGATCACGGTCAGCGCCGACTGTCGCTGGATCACCCGCGTGTTCGAATATCCCCACGCG
ACGGTGCGGCTGAACTTCTTTCGCGTGTTCGCGTGGCAGGGCACGCCGCACCCGCACGAAGGCCAGGTCTTTTCCTGGCA
GCGGCCCGAAGCGGTCGAAGTGACGCCGCTCCTGCCCGCCAATTTTCCGATCGTGAAAGCCTTGTCGCTGCCGCCGGTGC
TCGGCATCAGCCAGGCCGAGACCCTCGGCGCCGACAGCTTTCTCGCCCGGCTCGACGTCGCGCTCGCCGAGGGCCTGCGG
CTCATCCAGGTGCGTGACAAATCCCTGCCCGAGGACGAGCGCCTCCATCTCGCGCGCGAAACGGTCCGCCGCGCGCGCCG
CCATGGCGCGCGCGTACTGGTGAACGGCAGCGCCGATCTCGCGCAGGCCGCAGATGCCGACGGCGTCCACCTCGACGCCG
CCGCCGCAGCCCGCTGCAGCGTGCGGCCCGATTGCGAATGGGTCGGCGTGTCGTGCCACGATGCGGATGAACTGGCGCAG
GCGGCAGCGATCGGCGCCGACTTCGCGCTGCTCTCGCCCGTACTGCCCACACTCACCCACCCGGGCGCGCCGACGCTCGG
ATGGGCGCGCTTTTCCGCGCTCGCGGCGGCGAGCCCGATCCCGGTCTACGGCCTCGGCGGGCTAGCGCGCGACGACGTCG
CGCTGGCTCGCACGCGCGGCGCGCACGGTGTCGCTTTGCTGCGCGGGGCCTGGACATGA

Upstream 100 bases:

>100_bases
ACGCAGGCTTCGAGCGTGCCGCGCTGCAATGGGCGCAGGGCCGCGGGGCGCGCAACGGGCGGGTCGCCTCGCAGTTCGCG
CGCGACTGGGTGGGCAGGCG

Downstream 100 bases:

>100_bases
AGCGCGTCCTCCTGCCGCTGTTGTTGGTCGTCGCACTACTCGGCGTTGCGGTCGTCGGCTACTGGATGAAACGGCCCCTC
GAAGCGCAGACCGTCGCGTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MNAAVVEVVAAVLTQPDGRVLLAQRPAGKVYAGHWEFPGGKVEAGETLEDALVRELREELGITVSADCRWITRVFEYPHA
TVRLNFFRVFAWQGTPHPHEGQVFSWQRPEAVEVTPLLPANFPIVKALSLPPVLGISQAETLGADSFLARLDVALAEGLR
LIQVRDKSLPEDERLHLARETVRRARRHGARVLVNGSADLAQAADADGVHLDAAAAARCSVRPDCEWVGVSCHDADELAQ
AAAIGADFALLSPVLPTLTHPGAPTLGWARFSALAAASPIPVYGLGGLARDDVALARTRGAHGVALLRGAWT

Sequences:

>Translated_312_residues
MNAAVVEVVAAVLTQPDGRVLLAQRPAGKVYAGHWEFPGGKVEAGETLEDALVRELREELGITVSADCRWITRVFEYPHA
TVRLNFFRVFAWQGTPHPHEGQVFSWQRPEAVEVTPLLPANFPIVKALSLPPVLGISQAETLGADSFLARLDVALAEGLR
LIQVRDKSLPEDERLHLARETVRRARRHGARVLVNGSADLAQAADADGVHLDAAAAARCSVRPDCEWVGVSCHDADELAQ
AAAIGADFALLSPVLPTLTHPGAPTLGWARFSALAAASPIPVYGLGGLARDDVALARTRGAHGVALLRGAWT
>Mature_312_residues
MNAAVVEVVAAVLTQPDGRVLLAQRPAGKVYAGHWEFPGGKVEAGETLEDALVRELREELGITVSADCRWITRVFEYPHA
TVRLNFFRVFAWQGTPHPHEGQVFSWQRPEAVEVTPLLPANFPIVKALSLPPVLGISQAETLGADSFLARLDVALAEGLR
LIQVRDKSLPEDERLHLARETVRRARRHGARVLVNGSADLAQAADADGVHLDAAAAARCSVRPDCEWVGVSCHDADELAQ
AAAIGADFALLSPVLPTLTHPGAPTLGWARFSALAAASPIPVYGLGGLARDDVALARTRGAHGVALLRGAWT

Specific function: Specific For Pyrimidine Substrates. Acts On 5-Methyl- Dctp, Ctp And Dctp In Decreasing Order. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TMP-PPase family [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=124, Percent_Identity=43.5483870967742, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786288, Length=124, Percent_Identity=33.0645161290323, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022998
- InterPro:   IPR003733 [H]

Pfam domain/function: PF02581 TMP-TENI [H]

EC number: 3.6.1.-; 2.5.1.3

Molecular weight: Translated: 33368; Mature: 33368

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAAVVEVVAAVLTQPDGRVLLAQRPAGKVYAGHWEFPGGKVEAGETLEDALVRELREEL
CCHHHHHHHHHHHCCCCCCEEEEECCCCCEEECEEECCCCCCCCCCHHHHHHHHHHHHHH
GITVSADCRWITRVFEYPHATVRLNFFRVFAWQGTPHPHEGQVFSWQRPEAVEVTPLLPA
CCEEECCHHHHHHHHHCCCEEEEEEEEEEEEECCCCCCCCCCEEECCCCCCEEEEECCCC
NFPIVKALSLPPVLGISQAETLGADSFLARLDVALAEGLRLIQVRDKSLPEDERLHLARE
CCCEEEECCCCCCCCCCCHHHCCHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHH
TVRRARRHGARVLVNGSADLAQAADADGVHLDAAAAARCSVRPDCEWVGVSCHDADELAQ
HHHHHHHCCCEEEEECCCHHHHHCCCCCCEEEHHHHHHCCCCCCCCEEEEECCCHHHHHH
AAAIGADFALLSPVLPTLTHPGAPTLGWARFSALAAASPIPVYGLGGLARDDVALARTRG
HHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHCCC
AHGVALLRGAWT
CCCEEEEECCCC
>Mature Secondary Structure
MNAAVVEVVAAVLTQPDGRVLLAQRPAGKVYAGHWEFPGGKVEAGETLEDALVRELREEL
CCHHHHHHHHHHHCCCCCCEEEEECCCCCEEECEEECCCCCCCCCCHHHHHHHHHHHHHH
GITVSADCRWITRVFEYPHATVRLNFFRVFAWQGTPHPHEGQVFSWQRPEAVEVTPLLPA
CCEEECCHHHHHHHHHCCCEEEEEEEEEEEEECCCCCCCCCCEEECCCCCCEEEEECCCC
NFPIVKALSLPPVLGISQAETLGADSFLARLDVALAEGLRLIQVRDKSLPEDERLHLARE
CCCEEEECCCCCCCCCCCHHHCCHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHH
TVRRARRHGARVLVNGSADLAQAADADGVHLDAAAAARCSVRPDCEWVGVSCHDADELAQ
HHHHHHHCCCEEEEECCCHHHHHCCCCCCEEEHHHHHHCCCCCCCCEEEEECCCHHHHHH
AAAIGADFALLSPVLPTLTHPGAPTLGWARFSALAAASPIPVYGLGGLARDDVALARTRG
HHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHCCC
AHGVALLRGAWT
CCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]