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The map label for this gene is qor [C]

Identifier: 73539672

GI number: 73539672

Start: 2690131

End: 2691108

Strand: Reverse

Name: qor [C]

Synonym: Reut_B5852

Alternate gene names: 73539672

Gene position: 2691108-2690131 (Counterclockwise)

Preceding gene: 73539673

Following gene: 73539671

Centisome position: 98.71

GC content: 67.18

Gene sequence:

>978_bases
ATGAACACGATTCGCGTCAGCGAGAAAGCCTCAGGCATCGATACCCTGAAACTGGAACTGGTGGGCGCACCGCGCCCTGA
AGCCACCGATGGCCAGTGCGTGATCGAAGTAGCGAGCGCTGGAGTCAACCCGAGCGACGTCAAGGCCACGCTCGGCCTGA
TGCCGCATGCGGTCTGGCCGCGTACGCCGGGCCGCGACTATGCGGGCACCGTGGTCGACGGCCCCACTGGCATGATTGGC
CTGACCGTATGGGGCAGCGGCGGCGAGCTGGGCATTCGCCGCGACGGCACGCATGGCAAATACCTGAGCGTCAACGCGCA
GTCGGTGCGCGAAAAGCCGGCCACGCTGTCGCTGCTCGAAGCCGGCGCGGTCGGCGTGCCCTTCATCACCGCGTATGAAG
GCCTGCGCCGCGCGGGCATGCCGAAGCCCGGCAGCGTCGTGCTGGTGTGCGGCGGCAACGGCAAGGTTGGCCAGGCGACC
ATCCAGATCGCCACCGCGCTGGGCGCGCGCGTGTTTGCCGTGGAGCGCACCGAGGAGCCCTACCGTGGCCACGCGAACGC
CGCGGTGCGCATGATCGACGCAAGCAAAGAATCGATTTCCGCCGTGGTGCGCGACGAGACCGACGGCCATGGCGCCGACA
TCGTCTACAACACCGTGGGCAGCCCGTATTTCGAGCAGGCCAACCAGGCCATGGCGATCGGCGCCACGCAGATCTTCATC
TCGACGATCGAGCGTCCGGTGCCGTTCGACATCTTCACGTTCTATCGCGGCCAGCACACCTACGTGGGCGTCGATACGCT
GGCGCTTGACAGCAGCGCGGGCGCAAACATCCTGGACCAGCTCGCGCCGATGTTCGCCTCTGGCGCGCTGAAGCCGTTCC
CTGTGCTGCCCGAATACACGTATGCGCTGGCCGACGCCGCCGACGCCTATCGCGCCGTGCTGCAGGGCGCGACCGAACGC
GTGGTGCTCAAGCCATGA

Upstream 100 bases:

>100_bases
CTGGGCGGCGAGATCGCCTCGCCGCACGAAGCGCGCCGCGTACTTGGCTTGCGCGAAGCCTGAGCATTCACAACACCGAA
CACTGAACGAGGAAGACACC

Downstream 100 bases:

>100_bases
ACACGACCCGCTTCGCCCAGGCGCCAGCCTACTTTCCGCCGAACCACGACGGCATGCACTGCCTGCGCCTGCAGGGCCAC
GAGGCCGGGCCGTCGGAATC

Product: zinc-containing alcohol dehydrogenase superfamily protein

Products: NA

Alternate protein names: Acryloyl-CoA reductase [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MNTIRVSEKASGIDTLKLELVGAPRPEATDGQCVIEVASAGVNPSDVKATLGLMPHAVWPRTPGRDYAGTVVDGPTGMIG
LTVWGSGGELGIRRDGTHGKYLSVNAQSVREKPATLSLLEAGAVGVPFITAYEGLRRAGMPKPGSVVLVCGGNGKVGQAT
IQIATALGARVFAVERTEEPYRGHANAAVRMIDASKESISAVVRDETDGHGADIVYNTVGSPYFEQANQAMAIGATQIFI
STIERPVPFDIFTFYRGQHTYVGVDTLALDSSAGANILDQLAPMFASGALKPFPVLPEYTYALADAADAYRAVLQGATER
VVLKP

Sequences:

>Translated_325_residues
MNTIRVSEKASGIDTLKLELVGAPRPEATDGQCVIEVASAGVNPSDVKATLGLMPHAVWPRTPGRDYAGTVVDGPTGMIG
LTVWGSGGELGIRRDGTHGKYLSVNAQSVREKPATLSLLEAGAVGVPFITAYEGLRRAGMPKPGSVVLVCGGNGKVGQAT
IQIATALGARVFAVERTEEPYRGHANAAVRMIDASKESISAVVRDETDGHGADIVYNTVGSPYFEQANQAMAIGATQIFI
STIERPVPFDIFTFYRGQHTYVGVDTLALDSSAGANILDQLAPMFASGALKPFPVLPEYTYALADAADAYRAVLQGATER
VVLKP
>Mature_325_residues
MNTIRVSEKASGIDTLKLELVGAPRPEATDGQCVIEVASAGVNPSDVKATLGLMPHAVWPRTPGRDYAGTVVDGPTGMIG
LTVWGSGGELGIRRDGTHGKYLSVNAQSVREKPATLSLLEAGAVGVPFITAYEGLRRAGMPKPGSVVLVCGGNGKVGQAT
IQIATALGARVFAVERTEEPYRGHANAAVRMIDASKESISAVVRDETDGHGADIVYNTVGSPYFEQANQAMAIGATQIFI
STIERPVPFDIFTFYRGQHTYVGVDTLALDSSAGANILDQLAPMFASGALKPFPVLPEYTYALADAADAYRAVLQGATER
VVLKP

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the acryloyl- CoA dependent NADPH oxidation and formation of propionyl-CoA [H]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI194239676, Length=185, Percent_Identity=31.8918918918919, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI194239674, Length=185, Percent_Identity=31.8918918918919, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI13236495, Length=185, Percent_Identity=31.8918918918919, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=221, Percent_Identity=29.4117647058824, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.3.1.84 [H]

Molecular weight: Translated: 34130; Mature: 34130

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTIRVSEKASGIDTLKLELVGAPRPEATDGQCVIEVASAGVNPSDVKATLGLMPHAVWP
CCCEECCCCCCCCEEEEEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCC
RTPGRDYAGTVVDGPTGMIGLTVWGSGGELGIRRDGTHGKYLSVNAQSVREKPATLSLLE
CCCCCCCCCEEECCCCCEEEEEEECCCCCEEEEECCCCCCEEEECHHHHHCCCCEEEEEC
AGAVGVPFITAYEGLRRAGMPKPGSVVLVCGGNGKVGQATIQIATALGARVFAVERTEEP
CCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHEEEEEHHHCCEEEEEECCCCC
YRGHANAAVRMIDASKESISAVVRDETDGHGADIVYNTVGSPYFEQANQAMAIGATQIFI
CCCCCCEEEEEEECCHHHHHEEEECCCCCCCCEEEEECCCCHHHHHCCCEEEEHHHHHHH
STIERPVPFDIFTFYRGQHTYVGVDTLALDSSAGANILDQLAPMFASGALKPFPVLPEYT
HHHCCCCCCEEEEEECCCEEEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCHH
YALADAADAYRAVLQGATERVVLKP
HHHHHHHHHHHHHHCCCCCEEEECC
>Mature Secondary Structure
MNTIRVSEKASGIDTLKLELVGAPRPEATDGQCVIEVASAGVNPSDVKATLGLMPHAVWP
CCCEECCCCCCCCEEEEEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCC
RTPGRDYAGTVVDGPTGMIGLTVWGSGGELGIRRDGTHGKYLSVNAQSVREKPATLSLLE
CCCCCCCCCEEECCCCCEEEEEEECCCCCEEEEECCCCCCEEEECHHHHHCCCCEEEEEC
AGAVGVPFITAYEGLRRAGMPKPGSVVLVCGGNGKVGQATIQIATALGARVFAVERTEEP
CCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHEEEEEHHHCCEEEEEECCCCC
YRGHANAAVRMIDASKESISAVVRDETDGHGADIVYNTVGSPYFEQANQAMAIGATQIFI
CCCCCCEEEEEEECCHHHHHEEEECCCCCCCCEEEEECCCCHHHHHCCCEEEEHHHHHHH
STIERPVPFDIFTFYRGQHTYVGVDTLALDSSAGANILDQLAPMFASGALKPFPVLPEYT
HHHCCCCCCEEEEEECCCEEEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCHH
YALADAADAYRAVLQGATERVVLKP
HHHHHHHHHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA