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The map label for this gene is ltrA [H]

Identifier: 73539649

GI number: 73539649

Start: 2659665

End: 2660642

Strand: Direct

Name: ltrA [H]

Synonym: Reut_B5829

Alternate gene names: 73539649

Gene position: 2659665-2660642 (Clockwise)

Preceding gene: 73539645

Following gene: 73539657

Centisome position: 97.56

GC content: 65.54

Gene sequence:

>978_bases
ATGACGAAAGCCAACGTAGAGGATCTTTGGGAGCACTTGCACTGGCTGGTCGTGCTGCACCAGCAGGGCAGCTTCAGCAA
GGCCGCCGCAAGGTTAGGCGTAAGCAAGGCCTCGATGAGCCAGCACATTGCCGATCTGGAAAAGGCCGCCGGCATCATGC
TCGTCCAGCGCACCACGCGCAGCGCGACGCTGACGGATGCCGGCCGTCAGCTGGTTGATTCGATGCGCGGGGCTTTCGAA
CAAATTGCCACGGGCTACGCCAATGTTCGCGATCTGGCGGGGGCGCCGCGTGGTTTCCTGCGTGTCACCGCGCCGGTGGC
GTTCTCCCGACAGCAGTTGGTGCCGCGGCTGCCGGAGTTCTTGCGCCGCTATCCGCAGATCCAGGTCGAGTTGGATATGT
CTGACCGCTTGCGCCCGCTTGCGCAGGAAGGCTTCGACATTGCCGTGCGGCATACATCCGCGCCGCCCGAAACCCATGTT
GCCTGGACGCTGGCGGCTACGCGTACGGTGCTGGTGGCAAGCCGGTCCTATCTCGGGACCAGAAGCTCGCCCGAATCGCC
TGAAGCGCTGGTCGATCACGCCTGCCTGCACTACCCGCGGCGGCAAGGCACCGCCACGTGGACCTTCGTGCCGGAGGCGC
CGGATGAAGGCGCAACGCATGCCGATCCGGTCACGGTTCCCGTGGCTGGCCCGCTCGCGGTCAATAACAGCGAGGCCTTG
CGCGACGCCGCCATTGAAGGTCTGGGTATCGCGCTGCTGCCGGACTTCAGTGCGCAGTCGGCGCTGGAAAGCGGGCGTCT
GGTCGAGCTGCTGCCGCAATGGCGCGCGACTGGTGCGTTTGGAGACTGGCTCTATGCGATCCGGCCGTACTCCGCGCATG
CGTCGCGCGTGTCGCAGGTCTTTGTCGAGTACCTAAGGGAGTCGTTCTCGCAGGGCTTCACGTTCCGCCCGCCGGCCCAG
GTGCAGCCAGCGCTGTAA

Upstream 100 bases:

>100_bases
AGCCATCCGCCGCCGAACTCACTGTTCAGGATTTTTAGATAGTGGCATGCTATGGCTACCGAAAAATAGACGCTGAAAGT
GACGCAGGAGGACTCCCGAA

Downstream 100 bases:

>100_bases
CCCCGCCTGCCGCCGCACAGACCTACCCGAGCCAGCCCGCAAGCATCATCAGGCTCGCTCAGAGATCCAGGACCAGCCGC
TGTGCCTTGCTCCGCGAAAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MTKANVEDLWEHLHWLVVLHQQGSFSKAAARLGVSKASMSQHIADLEKAAGIMLVQRTTRSATLTDAGRQLVDSMRGAFE
QIATGYANVRDLAGAPRGFLRVTAPVAFSRQQLVPRLPEFLRRYPQIQVELDMSDRLRPLAQEGFDIAVRHTSAPPETHV
AWTLAATRTVLVASRSYLGTRSSPESPEALVDHACLHYPRRQGTATWTFVPEAPDEGATHADPVTVPVAGPLAVNNSEAL
RDAAIEGLGIALLPDFSAQSALESGRLVELLPQWRATGAFGDWLYAIRPYSAHASRVSQVFVEYLRESFSQGFTFRPPAQ
VQPAL

Sequences:

>Translated_325_residues
MTKANVEDLWEHLHWLVVLHQQGSFSKAAARLGVSKASMSQHIADLEKAAGIMLVQRTTRSATLTDAGRQLVDSMRGAFE
QIATGYANVRDLAGAPRGFLRVTAPVAFSRQQLVPRLPEFLRRYPQIQVELDMSDRLRPLAQEGFDIAVRHTSAPPETHV
AWTLAATRTVLVASRSYLGTRSSPESPEALVDHACLHYPRRQGTATWTFVPEAPDEGATHADPVTVPVAGPLAVNNSEAL
RDAAIEGLGIALLPDFSAQSALESGRLVELLPQWRATGAFGDWLYAIRPYSAHASRVSQVFVEYLRESFSQGFTFRPPAQ
VQPAL
>Mature_324_residues
TKANVEDLWEHLHWLVVLHQQGSFSKAAARLGVSKASMSQHIADLEKAAGIMLVQRTTRSATLTDAGRQLVDSMRGAFEQ
IATGYANVRDLAGAPRGFLRVTAPVAFSRQQLVPRLPEFLRRYPQIQVELDMSDRLRPLAQEGFDIAVRHTSAPPETHVA
WTLAATRTVLVASRSYLGTRSSPESPEALVDHACLHYPRRQGTATWTFVPEAPDEGATHADPVTVPVAGPLAVNNSEALR
DAAIEGLGIALLPDFSAQSALESGRLVELLPQWRATGAFGDWLYAIRPYSAHASRVSQVFVEYLRESFSQGFTFRPPAQV
QPAL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=298, Percent_Identity=28.8590604026846, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI145693193, Length=282, Percent_Identity=31.9148936170213, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1786401, Length=261, Percent_Identity=28.735632183908, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI87081978, Length=307, Percent_Identity=27.6872964169381, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1787128, Length=285, Percent_Identity=28.7719298245614, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1787589, Length=309, Percent_Identity=28.4789644012945, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1789639, Length=254, Percent_Identity=27.5590551181102, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1789173, Length=245, Percent_Identity=29.7959183673469, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1786448, Length=291, Percent_Identity=26.8041237113402, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI157672245, Length=123, Percent_Identity=32.520325203252, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790011, Length=337, Percent_Identity=25.8160237388724, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787879, Length=159, Percent_Identity=30.8176100628931, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788706, Length=260, Percent_Identity=24.2307692307692, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788748, Length=121, Percent_Identity=32.2314049586777, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35611; Mature: 35480

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKANVEDLWEHLHWLVVLHQQGSFSKAAARLGVSKASMSQHIADLEKAAGIMLVQRTTR
CCCCCHHHHHHHHHHHEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEEECCC
SATLTDAGRQLVDSMRGAFEQIATGYANVRDLAGAPRGFLRVTAPVAFSRQQLVPRLPEF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHH
LRRYPQIQVELDMSDRLRPLAQEGFDIAVRHTSAPPETHVAWTLAATRTVLVASRSYLGT
HHHCCCEEEEECCHHHHHHHHHCCCEEEEEECCCCCCCCEEEEHHHHHHHHHEHHHHCCC
RSSPESPEALVDHACLHYPRRQGTATWTFVPEAPDEGATHADPVTVPVAGPLAVNNSEAL
CCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCCEEECCHHHH
RDAAIEGLGIALLPDFSAQSALESGRLVELLPQWRATGAFGDWLYAIRPYSAHASRVSQV
HHHHHCCCCEEEECCCCHHHHHHCCCHHHHHHHHHCCCCCHHHHHEECCCHHHHHHHHHH
FVEYLRESFSQGFTFRPPAQVQPAL
HHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TKANVEDLWEHLHWLVVLHQQGSFSKAAARLGVSKASMSQHIADLEKAAGIMLVQRTTR
CCCCHHHHHHHHHHHEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEEECCC
SATLTDAGRQLVDSMRGAFEQIATGYANVRDLAGAPRGFLRVTAPVAFSRQQLVPRLPEF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHH
LRRYPQIQVELDMSDRLRPLAQEGFDIAVRHTSAPPETHVAWTLAATRTVLVASRSYLGT
HHHCCCEEEEECCHHHHHHHHHCCCEEEEEECCCCCCCCEEEEHHHHHHHHHEHHHHCCC
RSSPESPEALVDHACLHYPRRQGTATWTFVPEAPDEGATHADPVTVPVAGPLAVNNSEAL
CCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCCEEECCHHHH
RDAAIEGLGIALLPDFSAQSALESGRLVELLPQWRATGAFGDWLYAIRPYSAHASRVSQV
HHHHHCCCCEEEECCCCHHHHHHCCCHHHHHHHHHCCCCCHHHHHEECCCHHHHHHHHHH
FVEYLRESFSQGFTFRPPAQVQPAL
HHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]