Click here to switch to the map view.

The map label for this gene is mhpA [H]

Identifier: 73539628

GI number: 73539628

Start: 2631464

End: 2633122

Strand: Reverse

Name: mhpA [H]

Synonym: Reut_B5808

Alternate gene names: 73539628

Gene position: 2633122-2631464 (Counterclockwise)

Preceding gene: 73539629

Following gene: 73539627

Centisome position: 96.59

GC content: 59.98

Gene sequence:

>1659_bases
ATGCAAGACGCGAACGCGCTCAACACATCCGTGTTGATTGTCGGCGCCGGCCCAACCGGGCTTACCCTCGCCAATATCCT
CGGCCAGCAGGGCATTGACACCATCATCATCGATCGCAAGCCATCCACTGTAGGGGAACCGCGAGCGGTTTCGATCGACG
ACGAATCTCTGCGAACCATGCAGGCAATCGGCCTCGCTGACGACGTATTGAAAGACGTGGTCAAGGGCTACGGCGTGCAC
TACTACACCCGCCCTGGCGGCATCTGCTTCGGCAAAGTGGAGCCCACGGCAAGCGAGTACGGCTTCCCGCGCCGCAACGC
ATTTCGCCAACCGCTGCTGGAGGCCACGCTCCGCAAGGGACTTGACCGCTTTGCCTGTGTTCGCGTTCTGTTCGAGCACA
CGCTAGTTGACTTTACGCAGGATGCAAACGGCGTCCGTGCAAACGTCGCGTGCAGCGATGGCCCGAAAACCATTGCGGCA
GCCTATGTCGTAGGCACCGACGGAGGTCGCAGCGGAGTTCGTCAGCAGATCGGCTCGACGCTCGTCGGCTCATCGTTCAA
CGCAAGATGGCTGGTGATCGATATCGAGAATGACGACGACTCGTTCTGGCAAACACGAGCGTTCTGCGACGCGGACCGTC
CCGTGGTCGACGTCCCGGGCCCCAACCGCACGCGCCGCTACGAGTTCCTCCTCAAGCCCGACGAGACGGACGACGCCATG
CTGAAACCAGAGCGCATTCGCGAATTGCTTCGGCCTTTCAAAGATGACAGGCCCGTAGACGTCGTCCGCAAGACCGTCTA
TACGTTTCACGCGCGCGTGGCTGACAAATGGCGCGTAGGCCGGGTGTTCCTTGCCGGAGACGCTGCACATTTGACCCCGC
CGTATGCGGGTCAAGGCATGAATAGCGGGGTTCGCGACGCACACAATCTCGGCTGGAAGCTTGCTGCCGTGCTCAACGGC
ATGATTGGGCCAAATGCACTGGACACCTACCAGCAGGAGCGTCGCATTCACGCCTGGGCGTTGATTCGTCTTGCGTTACA
ACTGGGTTTCGTCATGGCGCCCTCAAGCCGCTTTCAGGCATGGAGCACCTCCGCATTCTTCCGAGCGACGGCCTTCGTCC
CGCCGGTGCGTGATTTCTTCCTCAAGATGAAGTTCAAGCCGAAGCCGCGCTTCCGCGAAGGGCTCGTTGAAATTGAACAT
AGCAAACATCCGCGACTAGTCGGCTCCATGGCGCCCCAGCCGTTGGTTCGGGTAGAGGGCGGCGAAACCGTCCCCCTCGA
CGATCTCATCGGGCACCACTTCGGTCTACTCGCCATCGATGTCCCCACCGTGGCACTGCGATCTGTCTGCGACCTCCCTC
TCTGGACGCAACTGCAGGCAAGCAAGATTGTGCTTTGCGCGAATGGGATTCGTACCGGTGCAACCTTGGGTGGTTTCTCA
ACTGCGGCTGTCGACGAATTGCCAGCGAGTCTTGCGACTGCAAAGGGTTGCTTCATCCTGCTGCGTCCCGACCGATATAT
CGCTGGTGTTTTCGATGCAGACGGCGCCGAGCCGTTTGCGAAAAGCTACCAGCAACGAGCTCAGTCCAGACAGCAAGCTC
CAGACCTCATTTCGACTTTTCCACCAGCTCGCCAACCGCAATTGGTTGTGGCCGACTGA

Upstream 100 bases:

>100_bases
ATCTCCAAGATTGGCGTGCTGCGCAACACAATCCAGGACGAATGACGCAGCCGTGGGCGAACGCCGCACGATCCAGCGGT
CGTCCACGAAGGAGACAACC

Downstream 100 bases:

>100_bases
CGGAGCCAATCATGTCAACACTCCAGACTGACACGCCGCTCTCCCTGCATCATCTGCACGTCACCAGTGAAGCGCCGCAA
GCCTTGGCCACCTTCTATGC

Product: 3-(3-hydroxyphenyl)propionate hydroxylase

Products: NA

Alternate protein names: 3-HCI hydroxylase; 3-HPP hydroxylase [H]

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MQDANALNTSVLIVGAGPTGLTLANILGQQGIDTIIIDRKPSTVGEPRAVSIDDESLRTMQAIGLADDVLKDVVKGYGVH
YYTRPGGICFGKVEPTASEYGFPRRNAFRQPLLEATLRKGLDRFACVRVLFEHTLVDFTQDANGVRANVACSDGPKTIAA
AYVVGTDGGRSGVRQQIGSTLVGSSFNARWLVIDIENDDDSFWQTRAFCDADRPVVDVPGPNRTRRYEFLLKPDETDDAM
LKPERIRELLRPFKDDRPVDVVRKTVYTFHARVADKWRVGRVFLAGDAAHLTPPYAGQGMNSGVRDAHNLGWKLAAVLNG
MIGPNALDTYQQERRIHAWALIRLALQLGFVMAPSSRFQAWSTSAFFRATAFVPPVRDFFLKMKFKPKPRFREGLVEIEH
SKHPRLVGSMAPQPLVRVEGGETVPLDDLIGHHFGLLAIDVPTVALRSVCDLPLWTQLQASKIVLCANGIRTGATLGGFS
TAAVDELPASLATAKGCFILLRPDRYIAGVFDADGAEPFAKSYQQRAQSRQQAPDLISTFPPARQPQLVVAD

Sequences:

>Translated_552_residues
MQDANALNTSVLIVGAGPTGLTLANILGQQGIDTIIIDRKPSTVGEPRAVSIDDESLRTMQAIGLADDVLKDVVKGYGVH
YYTRPGGICFGKVEPTASEYGFPRRNAFRQPLLEATLRKGLDRFACVRVLFEHTLVDFTQDANGVRANVACSDGPKTIAA
AYVVGTDGGRSGVRQQIGSTLVGSSFNARWLVIDIENDDDSFWQTRAFCDADRPVVDVPGPNRTRRYEFLLKPDETDDAM
LKPERIRELLRPFKDDRPVDVVRKTVYTFHARVADKWRVGRVFLAGDAAHLTPPYAGQGMNSGVRDAHNLGWKLAAVLNG
MIGPNALDTYQQERRIHAWALIRLALQLGFVMAPSSRFQAWSTSAFFRATAFVPPVRDFFLKMKFKPKPRFREGLVEIEH
SKHPRLVGSMAPQPLVRVEGGETVPLDDLIGHHFGLLAIDVPTVALRSVCDLPLWTQLQASKIVLCANGIRTGATLGGFS
TAAVDELPASLATAKGCFILLRPDRYIAGVFDADGAEPFAKSYQQRAQSRQQAPDLISTFPPARQPQLVVAD
>Mature_552_residues
MQDANALNTSVLIVGAGPTGLTLANILGQQGIDTIIIDRKPSTVGEPRAVSIDDESLRTMQAIGLADDVLKDVVKGYGVH
YYTRPGGICFGKVEPTASEYGFPRRNAFRQPLLEATLRKGLDRFACVRVLFEHTLVDFTQDANGVRANVACSDGPKTIAA
AYVVGTDGGRSGVRQQIGSTLVGSSFNARWLVIDIENDDDSFWQTRAFCDADRPVVDVPGPNRTRRYEFLLKPDETDDAM
LKPERIRELLRPFKDDRPVDVVRKTVYTFHARVADKWRVGRVFLAGDAAHLTPPYAGQGMNSGVRDAHNLGWKLAAVLNG
MIGPNALDTYQQERRIHAWALIRLALQLGFVMAPSSRFQAWSTSAFFRATAFVPPVRDFFLKMKFKPKPRFREGLVEIEH
SKHPRLVGSMAPQPLVRVEGGETVPLDDLIGHHFGLLAIDVPTVALRSVCDLPLWTQLQASKIVLCANGIRTGATLGGFS
TAAVDELPASLATAKGCFILLRPDRYIAGVFDADGAEPFAKSYQQRAQSRQQAPDLISTFPPARQPQLVVAD

Specific function: Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3- hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI) [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pheA/tfdB FAD monooxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786543, Length=525, Percent_Identity=37.5238095238095, Blast_Score=345, Evalue=5e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 60574; Mature: 60574

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDANALNTSVLIVGAGPTGLTLANILGQQGIDTIIIDRKPSTVGEPRAVSIDDESLRTM
CCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEECCHHHHHHH
QAIGLADDVLKDVVKGYGVHYYTRPGGICFGKVEPTASEYGFPRRNAFRQPLLEATLRKG
HHHCHHHHHHHHHHHHCCEEEEECCCCEEEECCCCCHHHCCCCCHHHHHHHHHHHHHHHH
LDRFACVRVLFEHTLVDFTQDANGVRANVACSDGPKTIAAAYVVGTDGGRSGVRQQIGST
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEEEECCCCHHHHHHHHCHH
LVGSSFNARWLVIDIENDDDSFWQTRAFCDADRPVVDVPGPNRTRRYEFLLKPDETDDAM
HHCCCCCCEEEEEEEECCCCHHHHHHHHCCCCCCEEECCCCCCCCEEEEEECCCCCCCCC
LKPERIRELLRPFKDDRPVDVVRKTVYTFHARVADKWRVGRVFLAGDAAHLTPPYAGQGM
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEEECCHHHCCCCCCCCCC
NSGVRDAHNLGWKLAAVLNGMIGPNALDTYQQERRIHAWALIRLALQLGFVMAPSSRFQA
CCCCCHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC
WSTSAFFRATAFVPPVRDFFLKMKFKPKPRFREGLVEIEHSKHPRLVGSMAPQPLVRVEG
CCCCHHHEEEECCCCHHHHHEEEECCCCCCHHHHHEEECCCCCCCHHHCCCCCCEEEECC
GETVPLDDLIGHHFGLLAIDVPTVALRSVCDLPLWTQLQASKIVLCANGIRTGATLGGFS
CCCCCHHHHHHCCCCEEEEECHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCC
TAAVDELPASLATAKGCFILLRPDRYIAGVFDADGAEPFAKSYQQRAQSRQQAPDLISTF
HHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHC
PPARQPQLVVAD
CCCCCCCEEEEC
>Mature Secondary Structure
MQDANALNTSVLIVGAGPTGLTLANILGQQGIDTIIIDRKPSTVGEPRAVSIDDESLRTM
CCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEECCHHHHHHH
QAIGLADDVLKDVVKGYGVHYYTRPGGICFGKVEPTASEYGFPRRNAFRQPLLEATLRKG
HHHCHHHHHHHHHHHHCCEEEEECCCCEEEECCCCCHHHCCCCCHHHHHHHHHHHHHHHH
LDRFACVRVLFEHTLVDFTQDANGVRANVACSDGPKTIAAAYVVGTDGGRSGVRQQIGST
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEEEECCCCHHHHHHHHCHH
LVGSSFNARWLVIDIENDDDSFWQTRAFCDADRPVVDVPGPNRTRRYEFLLKPDETDDAM
HHCCCCCCEEEEEEEECCCCHHHHHHHHCCCCCCEEECCCCCCCCEEEEEECCCCCCCCC
LKPERIRELLRPFKDDRPVDVVRKTVYTFHARVADKWRVGRVFLAGDAAHLTPPYAGQGM
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEEECCHHHCCCCCCCCCC
NSGVRDAHNLGWKLAAVLNGMIGPNALDTYQQERRIHAWALIRLALQLGFVMAPSSRFQA
CCCCCHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC
WSTSAFFRATAFVPPVRDFFLKMKFKPKPRFREGLVEIEHSKHPRLVGSMAPQPLVRVEG
CCCCHHHEEEECCCCHHHHHEEEECCCCCCHHHHHEEECCCCCCCHHHCCCCCCEEEECC
GETVPLDDLIGHHFGLLAIDVPTVALRSVCDLPLWTQLQASKIVLCANGIRTGATLGGFS
CCCCCHHHHHHCCCCEEEEECHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCC
TAAVDELPASLATAKGCFILLRPDRYIAGVFDADGAEPFAKSYQQRAQSRQQAPDLISTF
HHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHC
PPARQPQLVVAD
CCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA