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The map label for this gene is yjjL [H]

Identifier: 73539611

GI number: 73539611

Start: 2615302

End: 2616666

Strand: Direct

Name: yjjL [H]

Synonym: Reut_B5791

Alternate gene names: 73539611

Gene position: 2615302-2616666 (Clockwise)

Preceding gene: 73539610

Following gene: 73539612

Centisome position: 95.93

GC content: 65.27

Gene sequence:

>1365_bases
ATGTTGGAAAGCCCCACCACAATCCAGTCGCCGCCCCGCAGCTCCGCGGTGGCCGCGCCGACGCCGGCGAAATCGGCGGT
GGCGCCAGGCGGCTGGGCTTTGCTGTGCGTGCTCACCCTGGTCTATATCGTGTCGTTCATAGACCGTGGGGCCATCTCGC
TGGTGGTCGGCCCCATCAAGCAGGATCTCGGGGCCACCGACCTGGAAGTGAGCTGGCTGCTCGGGCTGTCGTTCATGCTG
CTGTACAGCGTGCTGGGCATTCCTGCCGGCTACCTCGTCGATCTGTACCGGCGAAAGTATCTGCTGAGCGGCGCCATCCT
GATGTGGTCCGGCGTGCAGATGCTGTGCGGACTGAGCAATACGTACTGGCACCTGTTCCTCGCGCGTATCGGTCTCGGCG
TAGGGGAAGCCATGCTGCCGCCCGCGGCATCGTCGATGATCCGGGACGCCTTTCCGCCCGAGCGGCGCGGGCTCGCATTC
GGTATCTACAACATCGGACCGCTGCTGGGCACCGGGCTGGCGCTGGTGCTCGGCAGCTTCCTGCTGACGTTTGCGGCCAG
CGGAAAGCTGGCGGGCGTGCCGTTGCTGGGAGCGCTGAAGCCTTGGCAATTCGTCCTGATCGTTCCGGGCTTGCTTGGCG
TGCCGCTCGCCGCGTTGACGCTGCTGCTGCGCGAGCCGCCGCGACGCGATGCCGTCGTTCACGCGGACCGCGTCACCTAT
CCGGCTGCACTGCGTTTTGCATGGCAGCAGCGTGCCGTATACGGTCCGCTGTGGATCGCCATCTGCCTCTACGGTATCGC
CATCGGCAGCCAACTGGCGTGGCTGCCCGAAATCATCAACCGCTCGATGGGTATCGCACGCCCCGAGATCGGCAAGACGC
TTGGCGCGATCAGTTTGGTGGCTTCGCCGCTGGGGCTGCTGTTCTTCGGCAGTGTGGCGGACAAACTGCAGAAGCGCTGG
AGTGACGCACCGGTTCGCGTCGCGATCGGCTCGACTGCCGTGGCCGCGCTTATCACCGCCTGTTTTCCGCTGATTCACAG
CGCCCAACTCGGCGCCATCGCCTACGGCGCGCAGACGTTCTTCTTCGCGATTTTTGCGGTCGCTGGCGGCGCCACCATGG
CCAATTTCACGCCAGGCAACATGATGGGCAAGCTGACGGCCCTCTATTACCTCATCACCAACCTGCTCGGACTGGCGCTC
GGCCCCACCGTCTGTGCGCTGGTGGCGCGGCTGCTTTTCAATGGCCCAAACGCGCTCGGCCATGCATTTGTGGCGTGTTA
CGTGGTCTCTGTCGGCATAGCCGTGTGCCTGCTGGTGCGCGTCTCGCGAGCGCTCCAGGTTGCCACGCAGCGTCGCGCCT
CCTGA

Upstream 100 bases:

>100_bases
GTCGGGCCGCACCGCCGCGCGCGCGGCCCTGGAAGAAGACGCCTGGGACCGCTGAGTCCCAGGCAACGAGAGTTCGAAGA
ACCGATAAACGGAGACAATC

Downstream 100 bases:

>100_bases
TCCGCGGCGCCATGCCGCGCCACGCCCACGCCTCCGCTTTTGTCTGACCGCAAAAAGGGAAACTGCCAATGCATGCCGCT
GAAAAATCGCCATGGAAATA

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MLESPTTIQSPPRSSAVAAPTPAKSAVAPGGWALLCVLTLVYIVSFIDRGAISLVVGPIKQDLGATDLEVSWLLGLSFML
LYSVLGIPAGYLVDLYRRKYLLSGAILMWSGVQMLCGLSNTYWHLFLARIGLGVGEAMLPPAASSMIRDAFPPERRGLAF
GIYNIGPLLGTGLALVLGSFLLTFAASGKLAGVPLLGALKPWQFVLIVPGLLGVPLAALTLLLREPPRRDAVVHADRVTY
PAALRFAWQQRAVYGPLWIAICLYGIAIGSQLAWLPEIINRSMGIARPEIGKTLGAISLVASPLGLLFFGSVADKLQKRW
SDAPVRVAIGSTAVAALITACFPLIHSAQLGAIAYGAQTFFFAIFAVAGGATMANFTPGNMMGKLTALYYLITNLLGLAL
GPTVCALVARLLFNGPNALGHAFVACYVVSVGIAVCLLVRVSRALQVATQRRAS

Sequences:

>Translated_454_residues
MLESPTTIQSPPRSSAVAAPTPAKSAVAPGGWALLCVLTLVYIVSFIDRGAISLVVGPIKQDLGATDLEVSWLLGLSFML
LYSVLGIPAGYLVDLYRRKYLLSGAILMWSGVQMLCGLSNTYWHLFLARIGLGVGEAMLPPAASSMIRDAFPPERRGLAF
GIYNIGPLLGTGLALVLGSFLLTFAASGKLAGVPLLGALKPWQFVLIVPGLLGVPLAALTLLLREPPRRDAVVHADRVTY
PAALRFAWQQRAVYGPLWIAICLYGIAIGSQLAWLPEIINRSMGIARPEIGKTLGAISLVASPLGLLFFGSVADKLQKRW
SDAPVRVAIGSTAVAALITACFPLIHSAQLGAIAYGAQTFFFAIFAVAGGATMANFTPGNMMGKLTALYYLITNLLGLAL
GPTVCALVARLLFNGPNALGHAFVACYVVSVGIAVCLLVRVSRALQVATQRRAS
>Mature_454_residues
MLESPTTIQSPPRSSAVAAPTPAKSAVAPGGWALLCVLTLVYIVSFIDRGAISLVVGPIKQDLGATDLEVSWLLGLSFML
LYSVLGIPAGYLVDLYRRKYLLSGAILMWSGVQMLCGLSNTYWHLFLARIGLGVGEAMLPPAASSMIRDAFPPERRGLAF
GIYNIGPLLGTGLALVLGSFLLTFAASGKLAGVPLLGALKPWQFVLIVPGLLGVPLAALTLLLREPPRRDAVVHADRVTY
PAALRFAWQQRAVYGPLWIAICLYGIAIGSQLAWLPEIINRSMGIARPEIGKTLGAISLVASPLGLLFFGSVADKLQKRW
SDAPVRVAIGSTAVAALITACFPLIHSAQLGAIAYGAQTFFFAIFAVAGGATMANFTPGNMMGKLTALYYLITNLLGLAL
GPTVCALVARLLFNGPNALGHAFVACYVVSVGIAVCLLVRVSRALQVATQRRAS

Specific function: Responsible for the transport of L-galactonate from the periplasm across the inner membrane (Probable). Is essential for growth on L-galactonate as the sole carbon source [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI185136021, Length=449, Percent_Identity=24.4988864142539, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI215490102, Length=233, Percent_Identity=30.4721030042918, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI215490096, Length=216, Percent_Identity=31.4814814814815, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI14042968, Length=216, Percent_Identity=31.4814814814815, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI215490100, Length=193, Percent_Identity=32.1243523316062, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI215490098, Length=233, Percent_Identity=27.8969957081545, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI2367379, Length=283, Percent_Identity=24.7349823321555, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87082320, Length=309, Percent_Identity=23.6245954692557, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17539092, Length=435, Percent_Identity=22.0689655172414, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17557872, Length=236, Percent_Identity=25.4237288135593, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI17864456, Length=348, Percent_Identity=24.4252873563218, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24654039, Length=348, Percent_Identity=24.4252873563218, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24640209, Length=185, Percent_Identity=29.1891891891892, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24654041, Length=359, Percent_Identity=22.8412256267409, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24654037, Length=359, Percent_Identity=22.8412256267409, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24654044, Length=204, Percent_Identity=25.4901960784314, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47913; Mature: 47913

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLESPTTIQSPPRSSAVAAPTPAKSAVAPGGWALLCVLTLVYIVSFIDRGAISLVVGPIK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHEEEHHHH
QDLGATDLEVSWLLGLSFMLLYSVLGIPAGYLVDLYRRKYLLSGAILMWSGVQMLCGLSN
HHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
TYWHLFLARIGLGVGEAMLPPAASSMIRDAFPPERRGLAFGIYNIGPLLGTGLALVLGSF
HHHHHHHHHHHCCCCCHHCCCHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHH
LLTFAASGKLAGVPLLGALKPWQFVLIVPGLLGVPLAALTLLLREPPRRDAVVHADRVTY
HHHHHCCCCCCCCCHHCCCCCCHHEEECCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCH
PAALRFAWQQRAVYGPLWIAICLYGIAIGSQLAWLPEIINRSMGIARPEIGKTLGAISLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ASPLGLLFFGSVADKLQKRWSDAPVRVAIGSTAVAALITACFPLIHSAQLGAIAYGAQTF
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFAIFAVAGGATMANFTPGNMMGKLTALYYLITNLLGLALGPTVCALVARLLFNGPNALG
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
HAFVACYVVSVGIAVCLLVRVSRALQVATQRRAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLESPTTIQSPPRSSAVAAPTPAKSAVAPGGWALLCVLTLVYIVSFIDRGAISLVVGPIK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHEEEHHHH
QDLGATDLEVSWLLGLSFMLLYSVLGIPAGYLVDLYRRKYLLSGAILMWSGVQMLCGLSN
HHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
TYWHLFLARIGLGVGEAMLPPAASSMIRDAFPPERRGLAFGIYNIGPLLGTGLALVLGSF
HHHHHHHHHHHCCCCCHHCCCHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHH
LLTFAASGKLAGVPLLGALKPWQFVLIVPGLLGVPLAALTLLLREPPRRDAVVHADRVTY
HHHHHCCCCCCCCCHHCCCCCCHHEEECCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCH
PAALRFAWQQRAVYGPLWIAICLYGIAIGSQLAWLPEIINRSMGIARPEIGKTLGAISLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ASPLGLLFFGSVADKLQKRWSDAPVRVAIGSTAVAALITACFPLIHSAQLGAIAYGAQTF
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFAIFAVAGGATMANFTPGNMMGKLTALYYLITNLLGLALGPTVCALVARLLFNGPNALG
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
HAFVACYVVSVGIAVCLLVRVSRALQVATQRRAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]