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The map label for this gene is glcD [C]

Identifier: 73539585

GI number: 73539585

Start: 2589376

End: 2590719

Strand: Direct

Name: glcD [C]

Synonym: Reut_B5765

Alternate gene names: 73539585

Gene position: 2589376-2590719 (Clockwise)

Preceding gene: 73539584

Following gene: 73539586

Centisome position: 94.98

GC content: 65.85

Gene sequence:

>1344_bases
ATGGACGACCAGCTTCAACTCGCATCGTCGACCGAGATCGATGAGCGCTTTCTAAGGGACTGGAGCGGACTCGCCGTTGG
ACGACCCGCCCAAGTGTATCGCCCAACCACGACCGCGGAAGTCGCGGCCATCGTGCGCCGCTGCCACGAGGAAGGGCGCC
GGATCACGGTGCAGGGCGGCCTGACCGGGGTGGCCGGCGGTGCGGTGCCCGGCGAGGGTGACGTGGTGATCAACCTCGAA
CGCATGAACCGGATCGAAGAGATCGACGCTCTTGAAGGCGTGATGCAGGTCCAGGCTGGCGCGACGCTCCAGCAGGTCCA
GGAGGCGGCGGCAGATCAGGGCTGGATGTTCGCGGTCGACCTCGGCGCACGCGGCAGTTGCCAGATCGGCGGCAATGCAT
CGACCAATGCCGGCGGTATCCGCGTGATGCGCTACGGGACAATGCGCGACTCCGTGCTCGGCGTCGAGGCCGTGCTGCCC
AACGGCACTGCTGTCTCTTCGCTCTCCCGCCTGGTAAAGAACAGCACGGGACTGGATCCACGGTTCCTGTTCATCGGAAC
CGAAGGCACGCTGGGCATCATCACACGGCTAACCCTGCGGCTGCATCCGCCGATGGGCGATCTGGCGGCGGCGTGGGTGT
CGGCCGCCCGCTTCGAGGCACTGCCGCAACTGCTGCGTGCGCTCAAGCGCCGCCTGGGTTCGGCGATGTGCGCGTTCGAA
TTCATGTCCGACCGTTTCGTCAGTCTTGCGTCGCGCCTGACCGGGCAGCCGGCGCCAGTCGCTGCAGCGCCATGGCATGT
CCTGATCGAGGCGGCCGGCAATGTCGGGCAATCGATGGAGGATGCGCTGCAAGCAGCGTTGTCCGATGCGCTGGAAGCCG
GCGAGATCACCGACTGCGCATTTGCGGCATCGCTGTCGCATCGTGAAGCGTTCTGGCGTCTGCGCGAGTCAATCCCGGAA
GTCCTCACGCATCTCAAGCCGGCTGCGACGCTCGATCTCGGCCTGCCGTGGAGCGAGACTGCCAGCTACATCGGGCAACT
GGAAGCCGCGCTGCGGGATCGCCTGCCGGATGCGGAACACCTGTTCCTCGGGCATCTGGGCGACAACAACATCCACCTGA
TCAGCGGCCCCGTCGACGACGCCGGCGTGCACCTCGTCGACCAACTGGCCTACGCTGCACTGAAGGGCCGCGGGGGCACC
GTCAGCGCCGAACATGGCGTTGGCCGGCTGAAGAAGGAATACCTCCTGGTATCGCGCAAGCCCGAAGAGATCGCGCTGAT
GCGGTGCATCAAGCAGGCGATGGATCCGGCCGGCATACTGAATCCCGGCCGGATATTCGACTAG

Upstream 100 bases:

>100_bases
ATCGAGCACTACGGCGGCCCCGATATGGCCCATACGCTCGGCTCGTCCACATCCACGCCCGTGACGGCAAAGACCGCTGC
ATAAGACAGGGAGCGACATC

Downstream 100 bases:

>100_bases
CCTGGAGATCCACATGCATCGCAGAACCTTCATGGGTGCGCTGGGCGCGTCGCTGCTCGCCACGCTCGAACCGGCTTGGG
CGCAGGGCTATCCCAACGCG

Product: FAD linked oxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MDDQLQLASSTEIDERFLRDWSGLAVGRPAQVYRPTTTAEVAAIVRRCHEEGRRITVQGGLTGVAGGAVPGEGDVVINLE
RMNRIEEIDALEGVMQVQAGATLQQVQEAAADQGWMFAVDLGARGSCQIGGNASTNAGGIRVMRYGTMRDSVLGVEAVLP
NGTAVSSLSRLVKNSTGLDPRFLFIGTEGTLGIITRLTLRLHPPMGDLAAAWVSAARFEALPQLLRALKRRLGSAMCAFE
FMSDRFVSLASRLTGQPAPVAAAPWHVLIEAAGNVGQSMEDALQAALSDALEAGEITDCAFAASLSHREAFWRLRESIPE
VLTHLKPAATLDLGLPWSETASYIGQLEAALRDRLPDAEHLFLGHLGDNNIHLISGPVDDAGVHLVDQLAYAALKGRGGT
VSAEHGVGRLKKEYLLVSRKPEEIALMRCIKQAMDPAGILNPGRIFD

Sequences:

>Translated_447_residues
MDDQLQLASSTEIDERFLRDWSGLAVGRPAQVYRPTTTAEVAAIVRRCHEEGRRITVQGGLTGVAGGAVPGEGDVVINLE
RMNRIEEIDALEGVMQVQAGATLQQVQEAAADQGWMFAVDLGARGSCQIGGNASTNAGGIRVMRYGTMRDSVLGVEAVLP
NGTAVSSLSRLVKNSTGLDPRFLFIGTEGTLGIITRLTLRLHPPMGDLAAAWVSAARFEALPQLLRALKRRLGSAMCAFE
FMSDRFVSLASRLTGQPAPVAAAPWHVLIEAAGNVGQSMEDALQAALSDALEAGEITDCAFAASLSHREAFWRLRESIPE
VLTHLKPAATLDLGLPWSETASYIGQLEAALRDRLPDAEHLFLGHLGDNNIHLISGPVDDAGVHLVDQLAYAALKGRGGT
VSAEHGVGRLKKEYLLVSRKPEEIALMRCIKQAMDPAGILNPGRIFD
>Mature_447_residues
MDDQLQLASSTEIDERFLRDWSGLAVGRPAQVYRPTTTAEVAAIVRRCHEEGRRITVQGGLTGVAGGAVPGEGDVVINLE
RMNRIEEIDALEGVMQVQAGATLQQVQEAAADQGWMFAVDLGARGSCQIGGNASTNAGGIRVMRYGTMRDSVLGVEAVLP
NGTAVSSLSRLVKNSTGLDPRFLFIGTEGTLGIITRLTLRLHPPMGDLAAAWVSAARFEALPQLLRALKRRLGSAMCAFE
FMSDRFVSLASRLTGQPAPVAAAPWHVLIEAAGNVGQSMEDALQAALSDALEAGEITDCAFAASLSHREAFWRLRESIPE
VLTHLKPAATLDLGLPWSETASYIGQLEAALRDRLPDAEHLFLGHLGDNNIHLISGPVDDAGVHLVDQLAYAALKGRGGT
VSAEHGVGRLKKEYLLVSRKPEEIALMRCIKQAMDPAGILNPGRIFD

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI119964728, Length=426, Percent_Identity=36.8544600938967, Blast_Score=270, Evalue=3e-72,
Organism=Homo sapiens, GI37595756, Length=456, Percent_Identity=29.1666666666667, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI37595754, Length=480, Percent_Identity=28.125, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI4501993, Length=234, Percent_Identity=28.6324786324786, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1789351, Length=433, Percent_Identity=28.6374133949192, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1787977, Length=506, Percent_Identity=23.9130434782609, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI48994907, Length=188, Percent_Identity=27.1276595744681, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17534361, Length=433, Percent_Identity=33.256351039261, Blast_Score=241, Evalue=6e-64,
Organism=Caenorhabditis elegans, GI71992373, Length=450, Percent_Identity=28.8888888888889, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71992381, Length=452, Percent_Identity=28.3185840707965, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI71992392, Length=369, Percent_Identity=30.0813008130081, Blast_Score=132, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6320023, Length=453, Percent_Identity=33.7748344370861, Blast_Score=274, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6320764, Length=462, Percent_Identity=30.0865800865801, Blast_Score=237, Evalue=3e-63,
Organism=Saccharomyces cerevisiae, GI6320027, Length=439, Percent_Identity=29.3849658314351, Blast_Score=156, Evalue=6e-39,
Organism=Drosophila melanogaster, GI18921117, Length=426, Percent_Identity=34.9765258215962, Blast_Score=268, Evalue=4e-72,
Organism=Drosophila melanogaster, GI24639277, Length=426, Percent_Identity=34.9765258215962, Blast_Score=268, Evalue=4e-72,
Organism=Drosophila melanogaster, GI24639275, Length=426, Percent_Identity=34.9765258215962, Blast_Score=268, Evalue=4e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 47822; Mature: 47822

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDQLQLASSTEIDERFLRDWSGLAVGRPAQVYRPTTTAEVAAIVRRCHEEGRRITVQGG
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHCCCCCHHHHHHHHHHHHHCCCEEEEECC
LTGVAGGAVPGEGDVVINLERMNRIEEIDALEGVMQVQAGATLQQVQEAAADQGWMFAVD
CCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEE
LGARGSCQIGGNASTNAGGIRVMRYGTMRDSVLGVEAVLPNGTAVSSLSRLVKNSTGLDP
CCCCCCEEECCCCCCCCCCEEEEEECCCHHHHHHHEEECCCCHHHHHHHHHHHCCCCCCC
RFLFIGTEGTLGIITRLTLRLHPPMGDLAAAWVSAARFEALPQLLRALKRRLGSAMCAFE
EEEEEECCCCHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMSDRFVSLASRLTGQPAPVAAAPWHVLIEAAGNVGQSMEDALQAALSDALEAGEITDCA
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHH
FAASLSHREAFWRLRESIPEVLTHLKPAATLDLGLPWSETASYIGQLEAALRDRLPDAEH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCHH
LFLGHLGDNNIHLISGPVDDAGVHLVDQLAYAALKGRGGTVSAEHGVGRLKKEYLLVSRK
EEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHCHHHHHHHHHEECCC
PEEIALMRCIKQAMDPAGILNPGRIFD
CHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MDDQLQLASSTEIDERFLRDWSGLAVGRPAQVYRPTTTAEVAAIVRRCHEEGRRITVQGG
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHCCCCCHHHHHHHHHHHHHCCCEEEEECC
LTGVAGGAVPGEGDVVINLERMNRIEEIDALEGVMQVQAGATLQQVQEAAADQGWMFAVD
CCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEE
LGARGSCQIGGNASTNAGGIRVMRYGTMRDSVLGVEAVLPNGTAVSSLSRLVKNSTGLDP
CCCCCCEEECCCCCCCCCCEEEEEECCCHHHHHHHEEECCCCHHHHHHHHHHHCCCCCCC
RFLFIGTEGTLGIITRLTLRLHPPMGDLAAAWVSAARFEALPQLLRALKRRLGSAMCAFE
EEEEEECCCCHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMSDRFVSLASRLTGQPAPVAAAPWHVLIEAAGNVGQSMEDALQAALSDALEAGEITDCA
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHH
FAASLSHREAFWRLRESIPEVLTHLKPAATLDLGLPWSETASYIGQLEAALRDRLPDAEH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCHH
LFLGHLGDNNIHLISGPVDDAGVHLVDQLAYAALKGRGGTVSAEHGVGRLKKEYLLVSRK
EEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHCHHHHHHHHHEECCC
PEEIALMRCIKQAMDPAGILNPGRIFD
CHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]