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The map label for this gene is ttdB [H]

Identifier: 73539472

GI number: 73539472

Start: 2475178

End: 2475786

Strand: Reverse

Name: ttdB [H]

Synonym: Reut_B5650

Alternate gene names: 73539472

Gene position: 2475786-2475178 (Counterclockwise)

Preceding gene: 73539473

Following gene: 73539471

Centisome position: 90.82

GC content: 60.1

Gene sequence:

>609_bases
GTGAAAAAAGTCCTCACTACCCCCATCAAGGACGAAGATCTTGCGGATCTCAAGGTTGGCGACGTCGTCTATCTGACCGG
CCGCCTGGTGACCTGCCGCGACGTGGCACATCGCCGCCTGATCGAACAGGGGCGCGAACTTCCGGTCAACCTGGAGGGAG
GTGCCATCTTTCACGCCGGCCCGATCGTCCGCAAGAAGGAAGACGGCGGCTTCGAAATGGTCTCGATTGGCCCGACGACC
AGCATGCGAATGGAGAAGTTCGAGCGCGAGTTCATCAAGCAGACTGGCGTGAAGCTGATCGTCGGCAAAGGCGGCATGGG
TCCGGAAACCGCAGCCGGCTGCCAGGCAAACGTGGCAGTGCACGCGATATTTCCCGGCGGCTGCGCCGTGCTGGCGGCGA
CGCAGGTGGAGGAAATCGAAGGCGCGGAATGGCAGGACCTTGGTATGCCCGAGACCCTCTGGATCAACCGGGTCAAGGAA
TTCGGACCGTTGATCATCTCGATCGATACCAAGGGCAATAACCTGATCCAGCAGAACAAGGCCGAGTTCAACTCGCGCAA
GGCCCCGATCCTGGAGCGGATCAGCAAGGAACTGAGTTTCATCCGGTAA

Upstream 100 bases:

>100_bases
GCGTGGCGGTCAACACGGGCTGCTGGGCGCATCGCCGCGGCAAGATCCGCATCAACGCCGACATGTCTTACGAAATCATT
TCCCACGAAGGAGTCGTCCT

Downstream 100 bases:

>100_bases
TCGGCTCCGGCCCGACAACATCTGCGATGACCTGACAGCCGGGTGTCAGGCCAGAGTTGTACCTGCCGGCGATCGGCGCC
GGGGCATTGCCGCAGGTCAG

Product: L(+)-tartrate dehydratase subunit beta

Products: NA

Alternate protein names: L-TTD beta [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MKKVLTTPIKDEDLADLKVGDVVYLTGRLVTCRDVAHRRLIEQGRELPVNLEGGAIFHAGPIVRKKEDGGFEMVSIGPTT
SMRMEKFEREFIKQTGVKLIVGKGGMGPETAAGCQANVAVHAIFPGGCAVLAATQVEEIEGAEWQDLGMPETLWINRVKE
FGPLIISIDTKGNNLIQQNKAEFNSRKAPILERISKELSFIR

Sequences:

>Translated_202_residues
MKKVLTTPIKDEDLADLKVGDVVYLTGRLVTCRDVAHRRLIEQGRELPVNLEGGAIFHAGPIVRKKEDGGFEMVSIGPTT
SMRMEKFEREFIKQTGVKLIVGKGGMGPETAAGCQANVAVHAIFPGGCAVLAATQVEEIEGAEWQDLGMPETLWINRVKE
FGPLIISIDTKGNNLIQQNKAEFNSRKAPILERISKELSFIR
>Mature_202_residues
MKKVLTTPIKDEDLADLKVGDVVYLTGRLVTCRDVAHRRLIEQGRELPVNLEGGAIFHAGPIVRKKEDGGFEMVSIGPTT
SMRMEKFEREFIKQTGVKLIVGKGGMGPETAAGCQANVAVHAIFPGGCAVLAATQVEEIEGAEWQDLGMPETLWINRVKE
FGPLIISIDTKGNNLIQQNKAEFNSRKAPILERISKELSFIR

Specific function: Unknown

COG id: COG1838

COG function: function code C; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789443, Length=202, Percent_Identity=69.8019801980198, Blast_Score=293, Evalue=5e-81,
Organism=Escherichia coli, GI1790564, Length=191, Percent_Identity=31.9371727748691, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1787897, Length=180, Percent_Identity=31.1111111111111, Blast_Score=85, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004647 [H]

Pfam domain/function: PF05683 Fumerase_C [H]

EC number: =4.2.1.32 [H]

Molecular weight: Translated: 22199; Mature: 22199

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVLTTPIKDEDLADLKVGDVVYLTGRLVTCRDVAHRRLIEQGRELPVNLEGGAIFHAG
CCCCCCCCCCCCCCCCEEECCEEEEECCEEHHHHHHHHHHHHCCCCCCEEECCCEEEECC
PIVRKKEDGGFEMVSIGPTTSMRMEKFEREFIKQTGVKLIVGKGGMGPETAAGCQANVAV
CCEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCEEE
HAIFPGGCAVLAATQVEEIEGAEWQDLGMPETLWINRVKEFGPLIISIDTKGNNLIQQNK
EEEECCCEEEEEHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCHHHHHH
AEFNSRKAPILERISKELSFIR
HHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKVLTTPIKDEDLADLKVGDVVYLTGRLVTCRDVAHRRLIEQGRELPVNLEGGAIFHAG
CCCCCCCCCCCCCCCCEEECCEEEEECCEEHHHHHHHHHHHHCCCCCCEEECCCEEEECC
PIVRKKEDGGFEMVSIGPTTSMRMEKFEREFIKQTGVKLIVGKGGMGPETAAGCQANVAV
CCEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCEEE
HAIFPGGCAVLAATQVEEIEGAEWQDLGMPETLWINRVKEFGPLIISIDTKGNNLIQQNK
EEEECCCEEEEEHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCHHHHHH
AEFNSRKAPILERISKELSFIR
HHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]