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The map label for this gene is actP [H]

Identifier: 73539466

GI number: 73539466

Start: 2468828

End: 2470465

Strand: Reverse

Name: actP [H]

Synonym: Reut_B5644

Alternate gene names: 73539466

Gene position: 2470465-2468828 (Counterclockwise)

Preceding gene: 73539467

Following gene: 73539465

Centisome position: 90.62

GC content: 62.82

Gene sequence:

>1638_bases
ATGAAACGCCTATTGATCACCGCTGCCGCGCTGGCAGCAACCACCCCGGCCTTCGCGGCGACGCCTCCGGTCGGCCAGGG
CCTCAACCTGATTGCCATCGGCATGTTCGTGGTATTTGTCGCGGCGACGCTCGGCGTGACGCGCTGGGCAGCACGGCGCA
ACCACAGCGTTGCCGACCACTACGCGGCGGGCGGCAAGATCACTGCGATGCAAAATGGCTGGGCCATCGCCGGCGACTAT
ATGTCGGCAGCATCGCTGCTCGGTATCTCGGCGCTGGTCTTCACCAGCGGCTACGACGGGCTGATCTACTCGATTGGCTT
TCTGGCCAGCTGGCCGATCATCCTGTTCCTGATCGCCGAGCCGCTGCGCAACCTCGGGCGCTACACGCTGGCCGATGTCC
TGTCCTATCGCCTCAGGCAGCGGCCAATTCGTGGTTTCTCGGCATCGAGTTCGATCGTCATCGTGCTCCTGTACCTGGTC
TCGCAGATGGTCGGCGCCGGCAAGCTCGTGGAATTGCTGTTCGGCTTCAACTACACCTCGGCGGTCGTGCTGGTCGGCGT
GCTCATGGTCGTCTATGTGTTCTTTGGCGGCATGCTCGCGACCACCTGGATCCAGATCATCAAGGCGGTCATGCTGCTGG
CCGGTTGCGCATTCATGGCTTACATGGTGCTCAGCCGTTTCGGCTTCAGCCTGAACAGCCTGTTCGACCACGCCATTGCC
GCGCACGGCAAGCACGAGGCGATCATGCGTCCCGGCGGTCTGGTGTCCGATCCGGTCTCCGCCGTTTCACTGGGGCTGGC
GCTGATCTTCGGTACGGCTGGACTGCCGCACATCCTGATGCGCTTTTTCACCGTCGGCGATGTCAAGGCCGCACGCAAGA
GCGTGCTTTATGCGACCGGCATCGTCGGCACGGGCTATGCCATGATCATCGTGATCGGATTTGGCACGATCGCGCTGGTT
GCGCAGGATCCGCTGTACCACAATGGCGCGGGCGCAGTGATTGGCGGCGTGAACATGGTGGCCGTGCATCTGGCTCACGC
AGTCGGCGGCAATGTGTTCCTCGGCTTTATCTGCGCCGTGGCGTTCTCGACCATCCTGGCTGTCGTGGCAGGCCTGACGC
TCGCCGGATCTTCGGCGATCTCGCATGACCTCTATGCAACGGTCATCCGCAAGGGGCAAGCGTCCGACAAGGATGAGCTG
CGAGTGTCCCGCATGACCACGCTGGTGCTTGGTGTCCTGTCGATCCTGCTCGGCATTCTGTTCGAGAAGCAGACCATTGC
GTTCATCGTCAGCCTGACCTTCTCCATCGCGGCCAGCTCCAATTTCCCCGTGCTGCTTCTGTCGATCTACTGGCGCGGGC
TCACCACGCGCGGCGCCGTAGTCGGCGGCATGCTGGGCCTCGTGACGGCGGTCGTCCTGACGATCCTCAGCCCAACGGTC
TGGGTACAGGTGCTGGGACATGCGTCCGCAATCTACCCGTACGAATATCCGGCGCTGTTTTCGATGCTGGTGGCATTCCT
CGGCATCTACGTGTTCTCCGTGACCGACCGATCGCCTCGCGGCGCGTGGGAACGCGATGCCTACCAGAACCAGCGCGTAG
ATGGCGAACTGGGGCTCGGCAGTAAAACCGCCGGCTGA

Upstream 100 bases:

>100_bases
GCATGTTTGCCTTCACCTTTGCCCTGGTGGCCATTTACGTGCATCGCAGCAACACCGTCTACGACAAGATGATCGCGGAC
ATCCGCAAGGGACTTCAGCC

Downstream 100 bases:

>100_bases
CCGTTCCCCCATGATGAGAAGCGACCCGCGCAGGCTTCAGCGGGCCCGTCTTCTCATTTATCGCCCGATTGGTAGAATCC
TGACATTATCCGCATCACCA

Product: Na+/solute symporter

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MKRLLITAAALAATTPAFAATPPVGQGLNLIAIGMFVVFVAATLGVTRWAARRNHSVADHYAAGGKITAMQNGWAIAGDY
MSAASLLGISALVFTSGYDGLIYSIGFLASWPIILFLIAEPLRNLGRYTLADVLSYRLRQRPIRGFSASSSIVIVLLYLV
SQMVGAGKLVELLFGFNYTSAVVLVGVLMVVYVFFGGMLATTWIQIIKAVMLLAGCAFMAYMVLSRFGFSLNSLFDHAIA
AHGKHEAIMRPGGLVSDPVSAVSLGLALIFGTAGLPHILMRFFTVGDVKAARKSVLYATGIVGTGYAMIIVIGFGTIALV
AQDPLYHNGAGAVIGGVNMVAVHLAHAVGGNVFLGFICAVAFSTILAVVAGLTLAGSSAISHDLYATVIRKGQASDKDEL
RVSRMTTLVLGVLSILLGILFEKQTIAFIVSLTFSIAASSNFPVLLLSIYWRGLTTRGAVVGGMLGLVTAVVLTILSPTV
WVQVLGHASAIYPYEYPALFSMLVAFLGIYVFSVTDRSPRGAWERDAYQNQRVDGELGLGSKTAG

Sequences:

>Translated_545_residues
MKRLLITAAALAATTPAFAATPPVGQGLNLIAIGMFVVFVAATLGVTRWAARRNHSVADHYAAGGKITAMQNGWAIAGDY
MSAASLLGISALVFTSGYDGLIYSIGFLASWPIILFLIAEPLRNLGRYTLADVLSYRLRQRPIRGFSASSSIVIVLLYLV
SQMVGAGKLVELLFGFNYTSAVVLVGVLMVVYVFFGGMLATTWIQIIKAVMLLAGCAFMAYMVLSRFGFSLNSLFDHAIA
AHGKHEAIMRPGGLVSDPVSAVSLGLALIFGTAGLPHILMRFFTVGDVKAARKSVLYATGIVGTGYAMIIVIGFGTIALV
AQDPLYHNGAGAVIGGVNMVAVHLAHAVGGNVFLGFICAVAFSTILAVVAGLTLAGSSAISHDLYATVIRKGQASDKDEL
RVSRMTTLVLGVLSILLGILFEKQTIAFIVSLTFSIAASSNFPVLLLSIYWRGLTTRGAVVGGMLGLVTAVVLTILSPTV
WVQVLGHASAIYPYEYPALFSMLVAFLGIYVFSVTDRSPRGAWERDAYQNQRVDGELGLGSKTAG
>Mature_545_residues
MKRLLITAAALAATTPAFAATPPVGQGLNLIAIGMFVVFVAATLGVTRWAARRNHSVADHYAAGGKITAMQNGWAIAGDY
MSAASLLGISALVFTSGYDGLIYSIGFLASWPIILFLIAEPLRNLGRYTLADVLSYRLRQRPIRGFSASSSIVIVLLYLV
SQMVGAGKLVELLFGFNYTSAVVLVGVLMVVYVFFGGMLATTWIQIIKAVMLLAGCAFMAYMVLSRFGFSLNSLFDHAIA
AHGKHEAIMRPGGLVSDPVSAVSLGLALIFGTAGLPHILMRFFTVGDVKAARKSVLYATGIVGTGYAMIIVIGFGTIALV
AQDPLYHNGAGAVIGGVNMVAVHLAHAVGGNVFLGFICAVAFSTILAVVAGLTLAGSSAISHDLYATVIRKGQASDKDEL
RVSRMTTLVLGVLSILLGILFEKQTIAFIVSLTFSIAASSNFPVLLLSIYWRGLTTRGAVVGGMLGLVTAVVLTILSPTV
WVQVLGHASAIYPYEYPALFSMLVAFLGIYVFSVTDRSPRGAWERDAYQNQRVDGELGLGSKTAG

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=480, Percent_Identity=24.7916666666667, Blast_Score=94, Evalue=4e-19,
Organism=Escherichia coli, GI1790503, Length=548, Percent_Identity=66.0583941605839, Blast_Score=700, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=503, Percent_Identity=26.8389662027833, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI87082237, Length=470, Percent_Identity=23.4042553191489, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 57537; Mature: 57537

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLLITAAALAATTPAFAATPPVGQGLNLIAIGMFVVFVAATLGVTRWAARRNHSVADH
CCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
YAAGGKITAMQNGWAIAGDYMSAASLLGISALVFTSGYDGLIYSIGFLASWPIILFLIAE
HCCCCEEEEECCCCEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
PLRNLGRYTLADVLSYRLRQRPIRGFSASSSIVIVLLYLVSQMVGAGKLVELLFGFNYTS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHH
AVVLVGVLMVVYVFFGGMLATTWIQIIKAVMLLAGCAFMAYMVLSRFGFSLNSLFDHAIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AHGKHEAIMRPGGLVSDPVSAVSLGLALIFGTAGLPHILMRFFTVGDVKAARKSVLYATG
HCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
IVGTGYAMIIVIGFGTIALVAQDPLYHNGAGAVIGGVNMVAVHLAHAVGGNVFLGFICAV
CCCCCCEEEEEEHHHHEEEEECCCCEECCCCHHHCCHHHHHHHHHHHHCCHHHHHHHHHH
AFSTILAVVAGLTLAGSSAISHDLYATVIRKGQASDKDELRVSRMTTLVLGVLSILLGIL
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FEKQTIAFIVSLTFSIAASSNFPVLLLSIYWRGLTTRGAVVGGMLGLVTAVVLTILSPTV
HHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WVQVLGHASAIYPYEYPALFSMLVAFLGIYVFSVTDRSPRGAWERDAYQNQRVDGELGLG
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCC
SKTAG
CCCCC
>Mature Secondary Structure
MKRLLITAAALAATTPAFAATPPVGQGLNLIAIGMFVVFVAATLGVTRWAARRNHSVADH
CCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
YAAGGKITAMQNGWAIAGDYMSAASLLGISALVFTSGYDGLIYSIGFLASWPIILFLIAE
HCCCCEEEEECCCCEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
PLRNLGRYTLADVLSYRLRQRPIRGFSASSSIVIVLLYLVSQMVGAGKLVELLFGFNYTS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHH
AVVLVGVLMVVYVFFGGMLATTWIQIIKAVMLLAGCAFMAYMVLSRFGFSLNSLFDHAIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AHGKHEAIMRPGGLVSDPVSAVSLGLALIFGTAGLPHILMRFFTVGDVKAARKSVLYATG
HCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
IVGTGYAMIIVIGFGTIALVAQDPLYHNGAGAVIGGVNMVAVHLAHAVGGNVFLGFICAV
CCCCCCEEEEEEHHHHEEEEECCCCEECCCCHHHCCHHHHHHHHHHHHCCHHHHHHHHHH
AFSTILAVVAGLTLAGSSAISHDLYATVIRKGQASDKDELRVSRMTTLVLGVLSILLGIL
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FEKQTIAFIVSLTFSIAASSNFPVLLLSIYWRGLTTRGAVVGGMLGLVTAVVLTILSPTV
HHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WVQVLGHASAIYPYEYPALFSMLVAFLGIYVFSVTDRSPRGAWERDAYQNQRVDGELGLG
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCC
SKTAG
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA