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The map label for this gene is pld [H]

Identifier: 73539400

GI number: 73539400

Start: 2395555

End: 2396259

Strand: Reverse

Name: pld [H]

Synonym: Reut_B5578

Alternate gene names: 73539400

Gene position: 2396259-2395555 (Counterclockwise)

Preceding gene: 73539406

Following gene: 73539399

Centisome position: 87.9

GC content: 64.82

Gene sequence:

>705_bases
ATGCGGGCCTCCGTCCCCGAACCGAATCGCACCGTGACTCACCGATCCAAGCGCGCGGCCCTGTCCGCCCTACTGCTCGC
CACATGCGCAACCGGCCTGGCTCATGCCCGCTCCGCCTCGGCGCTCGACAGCATCACCGATACCATCAGCAGCACCTTCA
ACGACGCAATTTCAAAGCACATGCCCGACATCCCGGGCCAGAACGCGCGGCAGGATGCGTCGGCCCGTCCGGTCAACGCC
AAGCCGTTTGCGTCGGGCAGCGGCTATACCCTGTGCTTCGTCCCCGACGGGCTGAGCTGCCAGGACCTGCTCGTCAATGC
GATCCGCGGTACGCGCCGGCGGCTGCTGATCCAGGCCTACTCGTTCACCAGCAAGCCCATCGCCGAAGCCGTGGTGCAGG
CGCACAAGCGCGGCGTCGATGTACGCGTGATCGTCGACAAGAGCCAGGTGAGCGAACGCTACACCAGCGCCACCTTCCTC
AAGCACGCGGGCATTCCGGTCGTCATCGACACCAAGCCCGCGATCGCCCACAACAAGGTCATGGTGTTCGATGACCAGGC
CGTATTCACCGGGTCGTTCAACTTCACCAAGTCCGCCGAAGAACGCAACGCCGAGAACGGCATGCTGATCCGCGGCGACT
CGGCGGTGGTCAAGGCCTATACCGAGAACTGGAACGCGCGCTTCCAGCAGTCGTCCGCGTACTGA

Upstream 100 bases:

>100_bases
AGTAGACGCATGCGGTGAAAAGGACTGTTACACACGCGCGGCTTGTCCGGTGCGGAGCGTGCTGCTACGCTGCGGGCCCG
CATTGCCGCGCGGCGTGGCA

Downstream 100 bases:

>100_bases
GCCGTGGCCGGCGTGATCTGGCCGGCGGTGGCACACTTGCGGTTTGCCCATCCTTCATCCGTCACCAGGAACCCGCCATG
CCAGCCACTCCCAACAGCAA

Product: phospholipase D/transphosphatidylase

Products: NA

Alternate protein names: PLD; Choline phosphatase [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MRASVPEPNRTVTHRSKRAALSALLLATCATGLAHARSASALDSITDTISSTFNDAISKHMPDIPGQNARQDASARPVNA
KPFASGSGYTLCFVPDGLSCQDLLVNAIRGTRRRLLIQAYSFTSKPIAEAVVQAHKRGVDVRVIVDKSQVSERYTSATFL
KHAGIPVVIDTKPAIAHNKVMVFDDQAVFTGSFNFTKSAEERNAENGMLIRGDSAVVKAYTENWNARFQQSSAY

Sequences:

>Translated_234_residues
MRASVPEPNRTVTHRSKRAALSALLLATCATGLAHARSASALDSITDTISSTFNDAISKHMPDIPGQNARQDASARPVNA
KPFASGSGYTLCFVPDGLSCQDLLVNAIRGTRRRLLIQAYSFTSKPIAEAVVQAHKRGVDVRVIVDKSQVSERYTSATFL
KHAGIPVVIDTKPAIAHNKVMVFDDQAVFTGSFNFTKSAEERNAENGMLIRGDSAVVKAYTENWNARFQQSSAY
>Mature_234_residues
MRASVPEPNRTVTHRSKRAALSALLLATCATGLAHARSASALDSITDTISSTFNDAISKHMPDIPGQNARQDASARPVNA
KPFASGSGYTLCFVPDGLSCQDLLVNAIRGTRRRLLIQAYSFTSKPIAEAVVQAHKRGVDVRVIVDKSQVSERYTSATFL
KHAGIPVVIDTKPAIAHNKVMVFDDQAVFTGSFNFTKSAEERNAENGMLIRGDSAVVKAYTENWNARFQQSSAY

Specific function: Could be a virulence factor [H]

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PLD phosphodiesterase domain [H]

Homologues:

Organism=Homo sapiens, GI270265812, Length=111, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001736 [H]

Pfam domain/function: NA

EC number: =3.1.4.4 [H]

Molecular weight: Translated: 25342; Mature: 25342

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRASVPEPNRTVTHRSKRAALSALLLATCATGLAHARSASALDSITDTISSTFNDAISKH
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MPDIPGQNARQDASARPVNAKPFASGSGYTLCFVPDGLSCQDLLVNAIRGTRRRLLIQAY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
SFTSKPIAEAVVQAHKRGVDVRVIVDKSQVSERYTSATFLKHAGIPVVIDTKPAIAHNKV
CCCCCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEE
MVFDDQAVFTGSFNFTKSAEERNAENGMLIRGDSAVVKAYTENWNARFQQSSAY
EEEECCEEEECCCCCCCCHHHCCCCCCEEEECCCCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MRASVPEPNRTVTHRSKRAALSALLLATCATGLAHARSASALDSITDTISSTFNDAISKH
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MPDIPGQNARQDASARPVNAKPFASGSGYTLCFVPDGLSCQDLLVNAIRGTRRRLLIQAY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
SFTSKPIAEAVVQAHKRGVDVRVIVDKSQVSERYTSATFLKHAGIPVVIDTKPAIAHNKV
CCCCCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEE
MVFDDQAVFTGSFNFTKSAEERNAENGMLIRGDSAVVKAYTENWNARFQQSSAY
EEEECCEEEECCCCCCCCHHHCCCCCCEEEECCCCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]