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The map label for this gene is lcfB [H]

Identifier: 73539398

GI number: 73539398

Start: 2393091

End: 2394650

Strand: Reverse

Name: lcfB [H]

Synonym: Reut_B5576

Alternate gene names: 73539398

Gene position: 2394650-2393091 (Counterclockwise)

Preceding gene: 73539399

Following gene: 73539395

Centisome position: 87.84

GC content: 66.54

Gene sequence:

>1560_bases
ATGCAGTCAGAGCAGCAGCGCGCCCTGCGCAATACCATCCCTGACGCCGTCGGCCGCGCCGTCCGGCGCGATCCCGACAA
GACTGCCATCCGCTTCGGCGCCCGTAGCTGGACCTTCCGGCAACTGGACGAAGCCGCGGCATGCGTGGCGGGTGCGCTCG
CGCAGTGGGGCCTGCGGCCCGGCGACCGCGTCGCGGCCTTCGGCAAAAACTCCGATGCCTACGTGCTGCTGTGGCTCGCG
TGCTTGCGATCCGGCCTGATCCACGTACCGGTGAACTTCTCGATGACGCGAAGCGAAGCCGAGTACATCGTCACGCAATC
CGGTGCCAGCGCGATCTTTGCCGATCCTGCACTGGCCGAACGCGTGCAAGGGCTACCCTGCCGGGTGAGCGGCACGCTGC
ATGGTGGCGGTGATCACGACATCCTGATGGCAGCCGCGCAAGGGCCCGCGGCACCGGTGCTCGCGGAACTGGCCGACGAC
ACGCCGGCGCAGATTCTGTACACGTCCGGCACCACTTCCGCACCGAAGGGCGCCGTGCTTACGCATCGCGCGCTGCTGGC
CGAGTACGTGAGCACCATCGCGGCATGCGACGTGCGTGCATCGGATTATTCGCTCGCAGCGCTGCCGCTCTACCACTCGG
CGCAGATGCACGTATTCCTGATGCCGCTGCTGCTGAGCGGTGGCACCACGCTCATCGCCGACAGCCCCGAGGCCGGCTTC
TGCCTGCGCACCATCCACGACGAAGAGATCACGAGCTTCTTTGCGCCGCCCACGGTGTGGATCGCGCTGCTGCGGCATGC
CGATTTCGATCCCGCGCGGCTCGGCACGCTGACCAAGGCGTACTACGGCGCCTCGATCATGCCGGTGCCGGTGCTGCTCG
AACTGCAGGCGAAGCTGCCGGCGCTGCGCTTCTACAACTGCTACGGCCAGAGCGAGATCGGCCCGCTCGCCACGGTGCTC
GGTCCCGACGAGCATGCGGAGCGCCCGGCCTCTGCGGGACGGCCCGTGCTCAATGTGGAAACCCGCATCGTCGACGAGAA
GATGAACGACGTCGCGCCCGGCACGCTTGGTGAAATCGTGCACCGCTCGCCTCAGTTGCTGACCGAATACTGGGACAAGC
CGGAACAGACCGCCGAGGCATTCGCCGGTGGCTGGTTCCATTCCGGCGACCTCGGCTACATGGATGTCGCGGGCTACCTG
TATGTGGTGGACCGCATCAAGGACGTGATCAACTCGGGCGGCGTGCTGGTGTCGAGCCGCGAAGTCGAGGAGTGCCTGTA
CACCCATCCCGCTGTGGCCGAGGTGGCGGTGTTCGCGCTGTCGCACCCGAAGTGGGTGGAAGCCGTGACCGCTTGCGTGG
TGCTCAAGCGCGATACTGCAGCCACCGAAGAAACACTGGTCGCGCATGCACGCGATGCGCTGGCACCGTTCAAGGTGCCC
AAGCGCGTGGTGTTCGTGGCCGACCTGCCGCGCAATACGGCAGGCAAGCTGCTCAAGCGGAAGCTGCGTGAAGACTATGC
GGCGCTGTTCAGCGACGAGACAGGCGGAACGGGACGATAG

Upstream 100 bases:

>100_bases
GCCGGAGGGGCCCGCCTTGCCACCGGCGTGCGGCACGCCGTATGCTGAGCTGTCGAGCTTCAAGACTTGCTGGATCCAAA
CCACGATAACGGAGACCACC

Downstream 100 bases:

>100_bases
CGGGACAGTCTGCGGGCAAGGTGTGTCTGGCGGGGCCACTCGCCAGATACGGCGCCCGCCGCATTGACGAGCGCCTGTCT
CGGCCTCAATACGGCACGGC

Product: acyl-CoA synthetase

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase [H]

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MQSEQQRALRNTIPDAVGRAVRRDPDKTAIRFGARSWTFRQLDEAAACVAGALAQWGLRPGDRVAAFGKNSDAYVLLWLA
CLRSGLIHVPVNFSMTRSEAEYIVTQSGASAIFADPALAERVQGLPCRVSGTLHGGGDHDILMAAAQGPAAPVLAELADD
TPAQILYTSGTTSAPKGAVLTHRALLAEYVSTIAACDVRASDYSLAALPLYHSAQMHVFLMPLLLSGGTTLIADSPEAGF
CLRTIHDEEITSFFAPPTVWIALLRHADFDPARLGTLTKAYYGASIMPVPVLLELQAKLPALRFYNCYGQSEIGPLATVL
GPDEHAERPASAGRPVLNVETRIVDEKMNDVAPGTLGEIVHRSPQLLTEYWDKPEQTAEAFAGGWFHSGDLGYMDVAGYL
YVVDRIKDVINSGGVLVSSREVEECLYTHPAVAEVAVFALSHPKWVEAVTACVVLKRDTAATEETLVAHARDALAPFKVP
KRVVFVADLPRNTAGKLLKRKLREDYAALFSDETGGTGR

Sequences:

>Translated_519_residues
MQSEQQRALRNTIPDAVGRAVRRDPDKTAIRFGARSWTFRQLDEAAACVAGALAQWGLRPGDRVAAFGKNSDAYVLLWLA
CLRSGLIHVPVNFSMTRSEAEYIVTQSGASAIFADPALAERVQGLPCRVSGTLHGGGDHDILMAAAQGPAAPVLAELADD
TPAQILYTSGTTSAPKGAVLTHRALLAEYVSTIAACDVRASDYSLAALPLYHSAQMHVFLMPLLLSGGTTLIADSPEAGF
CLRTIHDEEITSFFAPPTVWIALLRHADFDPARLGTLTKAYYGASIMPVPVLLELQAKLPALRFYNCYGQSEIGPLATVL
GPDEHAERPASAGRPVLNVETRIVDEKMNDVAPGTLGEIVHRSPQLLTEYWDKPEQTAEAFAGGWFHSGDLGYMDVAGYL
YVVDRIKDVINSGGVLVSSREVEECLYTHPAVAEVAVFALSHPKWVEAVTACVVLKRDTAATEETLVAHARDALAPFKVP
KRVVFVADLPRNTAGKLLKRKLREDYAALFSDETGGTGR
>Mature_519_residues
MQSEQQRALRNTIPDAVGRAVRRDPDKTAIRFGARSWTFRQLDEAAACVAGALAQWGLRPGDRVAAFGKNSDAYVLLWLA
CLRSGLIHVPVNFSMTRSEAEYIVTQSGASAIFADPALAERVQGLPCRVSGTLHGGGDHDILMAAAQGPAAPVLAELADD
TPAQILYTSGTTSAPKGAVLTHRALLAEYVSTIAACDVRASDYSLAALPLYHSAQMHVFLMPLLLSGGTTLIADSPEAGF
CLRTIHDEEITSFFAPPTVWIALLRHADFDPARLGTLTKAYYGASIMPVPVLLELQAKLPALRFYNCYGQSEIGPLATVL
GPDEHAERPASAGRPVLNVETRIVDEKMNDVAPGTLGEIVHRSPQLLTEYWDKPEQTAEAFAGGWFHSGDLGYMDVAGYL
YVVDRIKDVINSGGVLVSSREVEECLYTHPAVAEVAVFALSHPKWVEAVTACVVLKRDTAATEETLVAHARDALAPFKVP
KRVVFVADLPRNTAGKLLKRKLREDYAALFSDETGGTGR

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Partially Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI156151445, Length=513, Percent_Identity=29.6296296296296, Blast_Score=185, Evalue=7e-47,
Organism=Homo sapiens, GI187761345, Length=530, Percent_Identity=28.6792452830189, Blast_Score=175, Evalue=7e-44,
Organism=Homo sapiens, GI187761343, Length=530, Percent_Identity=28.6792452830189, Blast_Score=175, Evalue=7e-44,
Organism=Homo sapiens, GI115511026, Length=497, Percent_Identity=27.9678068410463, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI42544132, Length=496, Percent_Identity=29.4354838709677, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI122937307, Length=502, Percent_Identity=28.0876494023904, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI58082049, Length=492, Percent_Identity=28.0487804878049, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI157311624, Length=497, Percent_Identity=27.7665995975855, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI157311622, Length=497, Percent_Identity=27.7665995975855, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI38505220, Length=504, Percent_Identity=27.1825396825397, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI13375727, Length=568, Percent_Identity=26.5845070422535, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI28416953, Length=541, Percent_Identity=25.6931608133087, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI40807357, Length=553, Percent_Identity=25.8589511754069, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI8923896, Length=538, Percent_Identity=25.092936802974, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI38524616, Length=553, Percent_Identity=24.5931283905967, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI227499619, Length=527, Percent_Identity=24.4781783681214, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI253970489, Length=551, Percent_Identity=24.5009074410163, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI195947378, Length=398, Percent_Identity=24.1206030150754, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI13325057, Length=547, Percent_Identity=24.8628884826325, Blast_Score=83, Evalue=7e-16,
Organism=Escherichia coli, GI1788107, Length=536, Percent_Identity=31.3432835820896, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI145693145, Length=515, Percent_Identity=30.4854368932039, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI221142682, Length=489, Percent_Identity=27.19836400818, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1786810, Length=501, Percent_Identity=27.7445109780439, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1790505, Length=563, Percent_Identity=23.9786856127886, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1786529, Length=560, Percent_Identity=25, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1789201, Length=363, Percent_Identity=27.2727272727273, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788595, Length=337, Percent_Identity=24.6290801186944, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1786801, Length=447, Percent_Identity=22.3713646532438, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17558820, Length=488, Percent_Identity=31.1475409836066, Blast_Score=210, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI32563687, Length=512, Percent_Identity=30.078125, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI71994694, Length=544, Percent_Identity=25.9191176470588, Blast_Score=170, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71994690, Length=544, Percent_Identity=25.9191176470588, Blast_Score=170, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71994703, Length=544, Percent_Identity=25.9191176470588, Blast_Score=170, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17559526, Length=540, Percent_Identity=25.9259259259259, Blast_Score=143, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17560308, Length=544, Percent_Identity=26.2867647058824, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17531443, Length=526, Percent_Identity=24.5247148288973, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71996755, Length=511, Percent_Identity=25.8317025440313, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17560140, Length=491, Percent_Identity=25.2545824847251, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17557194, Length=516, Percent_Identity=25.1937984496124, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17538037, Length=499, Percent_Identity=23.4468937875752, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71985884, Length=432, Percent_Identity=25.2314814814815, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71982997, Length=390, Percent_Identity=25.1282051282051, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71983001, Length=384, Percent_Identity=25, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6319699, Length=351, Percent_Identity=27.9202279202279, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6323182, Length=568, Percent_Identity=26.5845070422535, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6319264, Length=567, Percent_Identity=25.7495590828924, Blast_Score=111, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24581924, Length=516, Percent_Identity=25.1937984496124, Blast_Score=148, Evalue=7e-36,
Organism=Drosophila melanogaster, GI21356441, Length=474, Percent_Identity=25.7383966244726, Blast_Score=146, Evalue=4e-35,
Organism=Drosophila melanogaster, GI18859661, Length=498, Percent_Identity=27.3092369477912, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24648255, Length=509, Percent_Identity=26.3261296660118, Blast_Score=141, Evalue=9e-34,
Organism=Drosophila melanogaster, GI24648253, Length=505, Percent_Identity=25.7425742574257, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI19922652, Length=492, Percent_Identity=27.8455284552846, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24648260, Length=469, Percent_Identity=25.5863539445629, Blast_Score=136, Evalue=5e-32,
Organism=Drosophila melanogaster, GI21358303, Length=454, Percent_Identity=26.431718061674, Blast_Score=135, Evalue=7e-32,
Organism=Drosophila melanogaster, GI21355181, Length=478, Percent_Identity=26.5690376569038, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24653035, Length=489, Percent_Identity=26.5848670756646, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI161076582, Length=495, Percent_Identity=27.2727272727273, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI281365686, Length=493, Percent_Identity=23.1237322515213, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21356947, Length=505, Percent_Identity=25.9405940594059, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24648257, Length=513, Percent_Identity=25.7309941520468, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24667955, Length=557, Percent_Identity=24.7755834829443, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI62472339, Length=529, Percent_Identity=24.952741020794, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24656500, Length=494, Percent_Identity=26.7206477732794, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI21355225, Length=403, Percent_Identity=27.5434243176179, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24667959, Length=364, Percent_Identity=25.2747252747253, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI20130357, Length=462, Percent_Identity=23.1601731601732, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI45550496, Length=505, Percent_Identity=25.1485148514851, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI45552801, Length=503, Percent_Identity=25.2485089463221, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020459
- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.3 [H]

Molecular weight: Translated: 55958; Mature: 55958

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSEQQRALRNTIPDAVGRAVRRDPDKTAIRFGARSWTFRQLDEAAACVAGALAQWGLRP
CCCHHHHHHHHCCHHHHHHHHHCCCCHHHHEECCCCCHHHHHHHHHHHHHHHHHHCCCCC
GDRVAAFGKNSDAYVLLWLACLRSGLIHVPVNFSMTRSEAEYIVTQSGASAIFADPALAE
CCCEEEECCCCCHHHHHHHHHHHCCEEEECCCCEEECCCCCEEEEECCCCEEEECHHHHH
RVQGLPCRVSGTLHGGGDHDILMAAAQGPAAPVLAELADDTPAQILYTSGTTSAPKGAVL
HHCCCCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCHHH
THRALLAEYVSTIAACDVRASDYSLAALPLYHSAQMHVFLMPLLLSGGTTLIADSPEAGF
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCCE
CLRTIHDEEITSFFAPPTVWIALLRHADFDPARLGTLTKAYYGASIMPVPVLLELQAKLP
EEEECCHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHEEHHHCCC
ALRFYNCYGQSEIGPLATVLGPDEHAERPASAGRPVLNVETRIVDEKMNDVAPGTLGEIV
CEEEEECCCCCCCCCCCEECCCCHHHCCCHHCCCCEEEEHHHHHHHHHHCCCCCHHHHHH
HRSPQLLTEYWDKPEQTAEAFAGGWFHSGDLGYMDVAGYLYVVDRIKDVINSGGVLVSSR
HCCHHHHHHHCCCHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECH
EVEECLYTHPAVAEVAVFALSHPKWVEAVTACVVLKRDTAATEETLVAHARDALAPFKVP
HHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHEECCCCCHHHHHHHHHHHHCCCCCCC
KRVVFVADLPRNTAGKLLKRKLREDYAALFSDETGGTGR
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQSEQQRALRNTIPDAVGRAVRRDPDKTAIRFGARSWTFRQLDEAAACVAGALAQWGLRP
CCCHHHHHHHHCCHHHHHHHHHCCCCHHHHEECCCCCHHHHHHHHHHHHHHHHHHCCCCC
GDRVAAFGKNSDAYVLLWLACLRSGLIHVPVNFSMTRSEAEYIVTQSGASAIFADPALAE
CCCEEEECCCCCHHHHHHHHHHHCCEEEECCCCEEECCCCCEEEEECCCCEEEECHHHHH
RVQGLPCRVSGTLHGGGDHDILMAAAQGPAAPVLAELADDTPAQILYTSGTTSAPKGAVL
HHCCCCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCHHH
THRALLAEYVSTIAACDVRASDYSLAALPLYHSAQMHVFLMPLLLSGGTTLIADSPEAGF
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCCE
CLRTIHDEEITSFFAPPTVWIALLRHADFDPARLGTLTKAYYGASIMPVPVLLELQAKLP
EEEECCHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHEEHHHCCC
ALRFYNCYGQSEIGPLATVLGPDEHAERPASAGRPVLNVETRIVDEKMNDVAPGTLGEIV
CEEEEECCCCCCCCCCCEECCCCHHHCCCHHCCCCEEEEHHHHHHHHHHCCCCCHHHHHH
HRSPQLLTEYWDKPEQTAEAFAGGWFHSGDLGYMDVAGYLYVVDRIKDVINSGGVLVSSR
HCCHHHHHHHCCCHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECH
EVEECLYTHPAVAEVAVFALSHPKWVEAVTACVVLKRDTAATEETLVAHARDALAPFKVP
HHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHEECCCCCHHHHHHHHHHHHCCCCCCC
KRVVFVADLPRNTAGKLLKRKLREDYAALFSDETGGTGR
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]