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The map label for this gene is mprA [H]

Identifier: 73539386

GI number: 73539386

Start: 2381304

End: 2381840

Strand: Reverse

Name: mprA [H]

Synonym: Reut_B5564

Alternate gene names: 73539386

Gene position: 2381840-2381304 (Counterclockwise)

Preceding gene: 73539387

Following gene: 73539385

Centisome position: 87.37

GC content: 65.18

Gene sequence:

>537_bases
ATGAAATCATCTGTGCCACTATCCTGCGGCGCGGATGCCTCCCTCGCCATGTCCTTCGAACAACGTATGGATCGCTACTG
CGCGGCGCATCCGGATGCCCCGCGCGACCTGATCCTGGCATCCCGGCTGCTACTGCGCACCGCACGCCTGCTGCGTGACC
ACATCAACCGGAGCCTCGCGCAGTTCGACCTCGACCTGAATCAGTACCTCGTCCTCAGCATGCTTGCCGTCGATGAGGGA
CAGCCGAGCATGCCTTCCGAACTGAGTGCCACGATCGACGCCACGCGTACGCAGATGACCCGCCTGGTTGACGGCTTGGA
GGCTCGCAGCCTGGTGCGCCGGCAGGCTTCTGAACAGGACCGCCGCAGTCTGGAATTGACGCTCACGCCGGCTGGCCGGA
GGCTGCTCGAGCGAGCGCTGCCGCTTGTGCATGCGGCCTATGCCGAAGTGTGGGCGCCTGTCGGGGAAAACGCGCTGGCG
TCCAGCACGCGCGTGCTGAACCGCCTGCACCAGAGCCTGCTGGCGTTACAGCCATGA

Upstream 100 bases:

>100_bases
CGCGCCGCGTGTCGGCGAGTCTTCGCATAAGGCACGCCGCCAACGTCCGGGCTGGCGAAATTCGTCCCGGCTGATATAAT
TTCGTCTGAAACTATCTCAG

Downstream 100 bases:

>100_bases
GCGTCGGCTCTCGCTGGCAATCGCTCTGGCAGCTGCGCCTGAGCGTGCGCTGGCTGCGGTGGCTCAGCCACCGGCAGCGG
CAGACGCTGCTGATGATGCT

Product: regulatory protein MarR

Products: NA

Alternate protein names: Protein emrR [H]

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MKSSVPLSCGADASLAMSFEQRMDRYCAAHPDAPRDLILASRLLLRTARLLRDHINRSLAQFDLDLNQYLVLSMLAVDEG
QPSMPSELSATIDATRTQMTRLVDGLEARSLVRRQASEQDRRSLELTLTPAGRRLLERALPLVHAAYAEVWAPVGENALA
SSTRVLNRLHQSLLALQP

Sequences:

>Translated_178_residues
MKSSVPLSCGADASLAMSFEQRMDRYCAAHPDAPRDLILASRLLLRTARLLRDHINRSLAQFDLDLNQYLVLSMLAVDEG
QPSMPSELSATIDATRTQMTRLVDGLEARSLVRRQASEQDRRSLELTLTPAGRRLLERALPLVHAAYAEVWAPVGENALA
SSTRVLNRLHQSLLALQP
>Mature_178_residues
MKSSVPLSCGADASLAMSFEQRMDRYCAAHPDAPRDLILASRLLLRTARLLRDHINRSLAQFDLDLNQYLVLSMLAVDEG
QPSMPSELSATIDATRTQMTRLVDGLEARSLVRRQASEQDRRSLELTLTPAGRRLLERALPLVHAAYAEVWAPVGENALA
SSTRVLNRLHQSLLALQP

Specific function: Negative regulator of the multidrug operon emrAB [H]

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789040, Length=157, Percent_Identity=31.8471337579618, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 19756; Mature: 19756

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: PS01117 HTH_MARR_1 ; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSSVPLSCGADASLAMSFEQRMDRYCAAHPDAPRDLILASRLLLRTARLLRDHINRSLA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QFDLDLNQYLVLSMLAVDEGQPSMPSELSATIDATRTQMTRLVDGLEARSLVRRQASEQD
HHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRSLELTLTPAGRRLLERALPLVHAAYAEVWAPVGENALASSTRVLNRLHQSLLALQP
HHCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKSSVPLSCGADASLAMSFEQRMDRYCAAHPDAPRDLILASRLLLRTARLLRDHINRSLA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QFDLDLNQYLVLSMLAVDEGQPSMPSELSATIDATRTQMTRLVDGLEARSLVRRQASEQD
HHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRSLELTLTPAGRRLLERALPLVHAAYAEVWAPVGENALASSTRVLNRLHQSLLALQP
HHCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]