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The map label for this gene is yhcA [H]

Identifier: 73539385

GI number: 73539385

Start: 2379724

End: 2381307

Strand: Reverse

Name: yhcA [H]

Synonym: Reut_B5563

Alternate gene names: 73539385

Gene position: 2381307-2379724 (Counterclockwise)

Preceding gene: 73539386

Following gene: 73539382

Centisome position: 87.35

GC content: 66.35

Gene sequence:

>1584_bases
ATGAGCGTCGGCTCTCGCTGGCAATCGCTCTGGCAGCTGCGCCTGAGCGTGCGCTGGCTGCGGTGGCTCAGCCACCGGCA
GCGGCAGACGCTGCTGATGATGCTGCTGGCCCTGGCCACCGGCGTGGAATTCCTCGAGAACATCATGTTCGTGTTCGCGT
CGAGCCACATCATGGGCGGTCTCGACGCGGATCCCCGCAGCTTCGCGCTCGCGCAGGCCGCGTACGCCGTGGGCAGCATG
CTCATGATCCTGAAGCAGCAATGGCTGTCACGCCGCTTCGGCTACCGCTATTACCTGACCGGTGCGCTGCTGATCTTCAT
GGCGGGCACGCTGGGCGCCGCGACCAGCCACTCGCTCGCCCAACTGGTCGGAGCCCGCTTCGTGCAGGGTTTTGGCGGCG
GCGCGCTATTCACGAGCTGCCGCATCCTGGTCGCGGTGCTGTTCGGACCCGCCGACCGGCCGCGCGCAAGCCGCATCTTT
ATGACCGGCATTTTCGTGGCAAGCGCGCTGGGGCCTGCATTCGCAGCCGAACTGGTGGACCACGGCGTCTGGCAGGACGT
GTTCTACGGTGCCCTTCCTTTCGCCGCGCTGGCCGCGCTTGGCGCGTGGGTGCTGCTGCCCGATGCGGAGCCGCGCCGCC
CGGCACCGAGCCCCGGGCTCGGGCCGCTGCTGCTGTTCGGCGCTGCGGTAGTCACGCTTCAGGCGGCACTGACCGAAGCG
CGCTTCGACATTTTTTCGCATCCGCTCCGGCTGGCGCTGATCGCGGCCGCAGGCCTCGGTCTGCTTGCCGTGTTCCTCTG
GCACCAGTGGCACCACGAGACCCCGGTGCTGCATCTGCGCGCGCTGCGCAATCCGATCTACCTGGCCGGGATCGGCATGT
ACTTCGTGTACTACATGATCAACAACCTCAGCGCCTACGTGTTTCCGATCTACGCGGAGCAGGCACTGCGGATTCCGCTG
GCCACCACGGGCTGGCTCAACACCTTTGCCGCGATCGTCAGCCTTGTCGGGGTCATCATCTACCTGCGCTACGGCTCGAG
GCTGACCCGCAAGAAGCCGCTGATGGTGACCGGCCTGATGATGATGGCCGCCACGGCCTGGTGGTTTTCGCGCATGCCGC
CGGACGCAGGGCCGCCCGCGCTTGCTTGGGGTCTGGTCGGCAAGGGCCTGTTTGGCGTGATGGTGATCATCCCGATCGCC
GGGCTGACGTTCCGCTCACTGAGCGGCGAGGAATTCGCGCATGGCTACCGCAGCAAGAACCTGATGCGCCAGATCGCCAG
CTCGTTTGCTTCGGCCATCGGGGCAGTGCTGCTGCAGAACCGGCAGTTTGCCGTGCATGACAGTCTCGTGCACGCGCTCG
GGCAACGGGTCGCGGAAACCCAGCTCTGGATGCAGTCGGTGCAGGCGGCGTTGGCCGCTCGTGGCTTTGATGAAGCGCAG
GCTCGCCATGGCGCGATGGCGCAGCTTGCCGGGCTGGTCGAACAACAGGCCCGTCTGATTGCTTGCGAGGATATCTACCG
TCTGATTGCGGTGCTGGCGCTGACCGCTGCGGTGTACATGCTGCTGCAGCGCCGCCTGGACTAA

Upstream 100 bases:

>100_bases
CGGCCTATGCCGAAGTGTGGGCGCCTGTCGGGGAAAACGCGCTGGCGTCCAGCACGCGCGTGCTGAACCGCCTGCACCAG
AGCCTGCTGGCGTTACAGCC

Downstream 100 bases:

>100_bases
GGCGCTACGTGTGTGGGTGCCATCGATCGGGGCACCGGGCGGGAAATCAGAACAGCGTCAGAACGTCATCAAAACAGCGA
AAGCTGGCGCATGCCAAAGC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 527; Mature: 526

Protein sequence:

>527_residues
MSVGSRWQSLWQLRLSVRWLRWLSHRQRQTLLMMLLALATGVEFLENIMFVFASSHIMGGLDADPRSFALAQAAYAVGSM
LMILKQQWLSRRFGYRYYLTGALLIFMAGTLGAATSHSLAQLVGARFVQGFGGGALFTSCRILVAVLFGPADRPRASRIF
MTGIFVASALGPAFAAELVDHGVWQDVFYGALPFAALAALGAWVLLPDAEPRRPAPSPGLGPLLLFGAAVVTLQAALTEA
RFDIFSHPLRLALIAAAGLGLLAVFLWHQWHHETPVLHLRALRNPIYLAGIGMYFVYYMINNLSAYVFPIYAEQALRIPL
ATTGWLNTFAAIVSLVGVIIYLRYGSRLTRKKPLMVTGLMMMAATAWWFSRMPPDAGPPALAWGLVGKGLFGVMVIIPIA
GLTFRSLSGEEFAHGYRSKNLMRQIASSFASAIGAVLLQNRQFAVHDSLVHALGQRVAETQLWMQSVQAALAARGFDEAQ
ARHGAMAQLAGLVEQQARLIACEDIYRLIAVLALTAAVYMLLQRRLD

Sequences:

>Translated_527_residues
MSVGSRWQSLWQLRLSVRWLRWLSHRQRQTLLMMLLALATGVEFLENIMFVFASSHIMGGLDADPRSFALAQAAYAVGSM
LMILKQQWLSRRFGYRYYLTGALLIFMAGTLGAATSHSLAQLVGARFVQGFGGGALFTSCRILVAVLFGPADRPRASRIF
MTGIFVASALGPAFAAELVDHGVWQDVFYGALPFAALAALGAWVLLPDAEPRRPAPSPGLGPLLLFGAAVVTLQAALTEA
RFDIFSHPLRLALIAAAGLGLLAVFLWHQWHHETPVLHLRALRNPIYLAGIGMYFVYYMINNLSAYVFPIYAEQALRIPL
ATTGWLNTFAAIVSLVGVIIYLRYGSRLTRKKPLMVTGLMMMAATAWWFSRMPPDAGPPALAWGLVGKGLFGVMVIIPIA
GLTFRSLSGEEFAHGYRSKNLMRQIASSFASAIGAVLLQNRQFAVHDSLVHALGQRVAETQLWMQSVQAALAARGFDEAQ
ARHGAMAQLAGLVEQQARLIACEDIYRLIAVLALTAAVYMLLQRRLD
>Mature_526_residues
SVGSRWQSLWQLRLSVRWLRWLSHRQRQTLLMMLLALATGVEFLENIMFVFASSHIMGGLDADPRSFALAQAAYAVGSML
MILKQQWLSRRFGYRYYLTGALLIFMAGTLGAATSHSLAQLVGARFVQGFGGGALFTSCRILVAVLFGPADRPRASRIFM
TGIFVASALGPAFAAELVDHGVWQDVFYGALPFAALAALGAWVLLPDAEPRRPAPSPGLGPLLLFGAAVVTLQAALTEAR
FDIFSHPLRLALIAAAGLGLLAVFLWHQWHHETPVLHLRALRNPIYLAGIGMYFVYYMINNLSAYVFPIYAEQALRIPLA
TTGWLNTFAAIVSLVGVIIYLRYGSRLTRKKPLMVTGLMMMAATAWWFSRMPPDAGPPALAWGLVGKGLFGVMVIIPIAG
LTFRSLSGEEFAHGYRSKNLMRQIASSFASAIGAVLLQNRQFAVHDSLVHALGQRVAETQLWMQSVQAALAARGFDEAQA
RHGAMAQLAGLVEQQARLIACEDIYRLIAVLALTAAVYMLLQRRLD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=276, Percent_Identity=28.2608695652174, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789042, Length=480, Percent_Identity=20.8333333333333, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788710, Length=489, Percent_Identity=21.0633946830266, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790195, Length=234, Percent_Identity=27.3504273504274, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 57748; Mature: 57617

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVGSRWQSLWQLRLSVRWLRWLSHRQRQTLLMMLLALATGVEFLENIMFVFASSHIMGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 8969498 [H]