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The map label for this gene is ahpC [C]

Identifier: 73538809

GI number: 73538809

Start: 1710875

End: 1711528

Strand: Direct

Name: ahpC [C]

Synonym: Reut_B4984

Alternate gene names: 73538809

Gene position: 1710875-1711528 (Clockwise)

Preceding gene: 73538808

Following gene: 73538813

Centisome position: 62.76

GC content: 59.94

Gene sequence:

>654_bases
ATGGCGATTCGAATTGGCGAAGAAGCCCCTGACTTCACCGCCGAGACCACGCAAGGCACGATCCATTTCCATGAATGGAT
CGGAGACGGCTGGGCCATCCTGTTTTCGCATCCGAAGGACTTCACGCCCGTCTGCACGACCGAACTCGGCTATATGGCTG
GCCTCAAGCCCGAATTCGACAAGCGCAACACCAAGATCATCGGCCTGAGCATCGATCCGGTCGGCGACCACTCGCGCTGG
GCCAAGGACATCGAGGAAACACAGGGCCATGCGGTCAACTATCCGATGATCGGCGATGCCGACCTGAAGGTGGCCAAGCT
CTATGACATGATCCACCCCGAAGCCAGCGGCGGCCCGCGCACCGCCGTGGATAACGCGACCATCCGCTCGGTGTTCTGGA
TCGGGCCGGACAAGAAGATCAAGGCGATGCTGGCGTATCCGATGAGTGCCGGCCGCAATTTCGACGAAGTCCTGCGCCTG
CTGGATTCGCTGCAGCTCAACGCGAAGCATGCCGTGGCGACCCCGGTCAACTGGAAACCGGGAGATGACGTGATCATCCC
GACGTCGGTTTCGGACGAAGACGCACGGAAGAAATACCCGAATGGCTTCAAGACGTTGAAGCCCTACCTTCGGGTGGTGG
CCCAGCCAAAGTAA

Upstream 100 bases:

>100_bases
CGCACAAGGTCCTGACGCACAGTACGATTCCCGTGCTGGTGTTTCACTAGCGGCATTTCATTAGCCCCTTTGTCTTCACC
CCCAACCAAGGAGTTCGATC

Downstream 100 bases:

>100_bases
GGAGAATGGCGGGCGGAAGCGCCCGTCCGGTCCGCGTTTCCGGGTATCGCCTCATACTTAGGTATGAGGCGGACGGGGCC
CCCGGGAAAACTATCCACAG

Product: peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MAIRIGEEAPDFTAETTQGTIHFHEWIGDGWAILFSHPKDFTPVCTTELGYMAGLKPEFDKRNTKIIGLSIDPVGDHSRW
AKDIEETQGHAVNYPMIGDADLKVAKLYDMIHPEASGGPRTAVDNATIRSVFWIGPDKKIKAMLAYPMSAGRNFDEVLRL
LDSLQLNAKHAVATPVNWKPGDDVIIPTSVSDEDARKKYPNGFKTLKPYLRVVAQPK

Sequences:

>Translated_217_residues
MAIRIGEEAPDFTAETTQGTIHFHEWIGDGWAILFSHPKDFTPVCTTELGYMAGLKPEFDKRNTKIIGLSIDPVGDHSRW
AKDIEETQGHAVNYPMIGDADLKVAKLYDMIHPEASGGPRTAVDNATIRSVFWIGPDKKIKAMLAYPMSAGRNFDEVLRL
LDSLQLNAKHAVATPVNWKPGDDVIIPTSVSDEDARKKYPNGFKTLKPYLRVVAQPK
>Mature_216_residues
AIRIGEEAPDFTAETTQGTIHFHEWIGDGWAILFSHPKDFTPVCTTELGYMAGLKPEFDKRNTKIIGLSIDPVGDHSRWA
KDIEETQGHAVNYPMIGDADLKVAKLYDMIHPEASGGPRTAVDNATIRSVFWIGPDKKIKAMLAYPMSAGRNFDEVLRLL
DSLQLNAKHAVATPVNWKPGDDVIIPTSVSDEDARKKYPNGFKTLKPYLRVVAQPK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=227, Percent_Identity=48.4581497797357, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI4505591, Length=190, Percent_Identity=28.9473684210526, Blast_Score=87, Evalue=8e-18,
Organism=Homo sapiens, GI32455266, Length=190, Percent_Identity=28.9473684210526, Blast_Score=87, Evalue=8e-18,
Organism=Homo sapiens, GI32455264, Length=190, Percent_Identity=28.9473684210526, Blast_Score=87, Evalue=8e-18,
Organism=Homo sapiens, GI32189392, Length=190, Percent_Identity=26.8421052631579, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI5453549, Length=158, Percent_Identity=29.746835443038, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI32483377, Length=169, Percent_Identity=26.6272189349112, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI5802974, Length=169, Percent_Identity=26.6272189349112, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1786822, Length=159, Percent_Identity=27.0440251572327, Blast_Score=66, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25153706, Length=226, Percent_Identity=39.8230088495575, Blast_Score=164, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI193204376, Length=200, Percent_Identity=27.5, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI32565831, Length=200, Percent_Identity=27.5, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17554494, Length=158, Percent_Identity=25.3164556962025, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6319407, Length=212, Percent_Identity=51.8867924528302, Blast_Score=224, Evalue=6e-60,
Organism=Saccharomyces cerevisiae, GI6323613, Length=171, Percent_Identity=25.7309941520468, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24581278, Length=224, Percent_Identity=44.1964285714286, Blast_Score=191, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24652434, Length=208, Percent_Identity=46.1538461538462, Blast_Score=191, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24652436, Length=208, Percent_Identity=46.1538461538462, Blast_Score=190, Evalue=6e-49,
Organism=Drosophila melanogaster, GI17975518, Length=208, Percent_Identity=46.1538461538462, Blast_Score=190, Evalue=6e-49,
Organism=Drosophila melanogaster, GI17738015, Length=205, Percent_Identity=27.3170731707317, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17157991, Length=170, Percent_Identity=30.5882352941176, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24641739, Length=170, Percent_Identity=30.5882352941176, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21357347, Length=183, Percent_Identity=25.6830601092896, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24656348, Length=168, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI17864676, Length=168, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=7e-16,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 24115; Mature: 23984

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIRIGEEAPDFTAETTQGTIHFHEWIGDGWAILFSHPKDFTPVCTTELGYMAGLKPEFD
CEEEECCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCC
KRNTKIIGLSIDPVGDHSRWAKDIEETQGHAVNYPMIGDADLKVAKLYDMIHPEASGGPR
CCCCEEEEEEECCCCCHHHHHHHHHHHCCCEECCCEECCCCCHHHHHHHHHCCCCCCCCC
TAVDNATIRSVFWIGPDKKIKAMLAYPMSAGRNFDEVLRLLDSLQLNAKHAVATPVNWKP
CCCCCCEEEEEEEECCCHHEEHEEECCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCC
GDDVIIPTSVSDEDARKKYPNGFKTLKPYLRVVAQPK
CCCEEEECCCCCHHHHHHCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AIRIGEEAPDFTAETTQGTIHFHEWIGDGWAILFSHPKDFTPVCTTELGYMAGLKPEFD
EEEECCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCC
KRNTKIIGLSIDPVGDHSRWAKDIEETQGHAVNYPMIGDADLKVAKLYDMIHPEASGGPR
CCCCEEEEEEECCCCCHHHHHHHHHHHCCCEECCCEECCCCCHHHHHHHHHCCCCCCCCC
TAVDNATIRSVFWIGPDKKIKAMLAYPMSAGRNFDEVLRLLDSLQLNAKHAVATPVNWKP
CCCCCCEEEEEEEECCCHHEEHEEECCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCC
GDDVIIPTSVSDEDARKKYPNGFKTLKPYLRVVAQPK
CCCEEEECCCCCHHHHHHCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]