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The map label for this gene is rsbS [H]

Identifier: 73538796

GI number: 73538796

Start: 1698183

End: 1698542

Strand: Direct

Name: rsbS [H]

Synonym: Reut_B4971

Alternate gene names: 73538796

Gene position: 1698183-1698542 (Clockwise)

Preceding gene: 73538795

Following gene: 73538797

Centisome position: 62.29

GC content: 59.17

Gene sequence:

>360_bases
ATGGAACGGATTCCAATCTTGCGGATGGGCAAGCACCTGCTCGTGACCATCCAGATCGATATGCAGGACCAGACCGCTCT
GATGTTGCAGGAAGATCTGGCCGGGCAAATAGAAAAGAGCGGCGCACACGGCGTGCTGATCGATGTTTCGGCACTGGAAG
TAGTGGATTCCTTTATCGGCCGCATGCTCGTCAGCATTTCGGATATCGGCAGGTTGCTCGGCGCCACCACCGTCGTGGTG
GGTATCCGGCCCGCCGTGGCGATTACGCTGGTGGAGTTGGGATTATCGCTCGGAGGTGTGCGCACGGCGCTGAATGTGGA
GCGTGGCATGGCCATACTCGACGGCGTGCGGAGGAACTGA

Upstream 100 bases:

>100_bases
CATCACTACCAAGTCCACCCTGGCCGATGCGCTCGCCACCGCGATGCGCCTGACGGGACACACGGTGTCGCGCGGCGCTG
CCTGAGACGCAGAAACCGCC

Downstream 100 bases:

>100_bases
CGTGGCCGACGAACTGCCTGGCACCGGATGTGCGCCGCTCCGCGACGAGCGGGACATCGTGCAAGCGCGCGCCTTGGTCC
GCACATTGTCAGGCCAGCTC

Product: Sulfate transporter/antisigma-factor antagonist STAS

Products: NA

Alternate protein names: Stressosome protein rsbS [H]

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MERIPILRMGKHLLVTIQIDMQDQTALMLQEDLAGQIEKSGAHGVLIDVSALEVVDSFIGRMLVSISDIGRLLGATTVVV
GIRPAVAITLVELGLSLGGVRTALNVERGMAILDGVRRN

Sequences:

>Translated_119_residues
MERIPILRMGKHLLVTIQIDMQDQTALMLQEDLAGQIEKSGAHGVLIDVSALEVVDSFIGRMLVSISDIGRLLGATTVVV
GIRPAVAITLVELGLSLGGVRTALNVERGMAILDGVRRN
>Mature_119_residues
MERIPILRMGKHLLVTIQIDMQDQTALMLQEDLAGQIEKSGAHGVLIDVSALEVVDSFIGRMLVSISDIGRLLGATTVVV
GIRPAVAITLVELGLSLGGVRTALNVERGMAILDGVRRN

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 12712; Mature: 12712

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERIPILRMGKHLLVTIQIDMQDQTALMLQEDLAGQIEKSGAHGVLIDVSALEVVDSFIG
CCCCCCEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHH
RMLVSISDIGRLLGATTVVVGIRPAVAITLVELGLSLGGVRTALNVERGMAILDGVRRN
HHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHCCCC
>Mature Secondary Structure
MERIPILRMGKHLLVTIQIDMQDQTALMLQEDLAGQIEKSGAHGVLIDVSALEVVDSFIG
CCCCCCEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHH
RMLVSISDIGRLLGATTVVVGIRPAVAITLVELGLSLGGVRTALNVERGMAILDGVRRN
HHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 8824586; 8682789 [H]