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The map label for this gene is rsbRA [H]

Identifier: 73538795

GI number: 73538795

Start: 1697313

End: 1698167

Strand: Direct

Name: rsbRA [H]

Synonym: Reut_B4970

Alternate gene names: 73538795

Gene position: 1697313-1698167 (Clockwise)

Preceding gene: 73538794

Following gene: 73538796

Centisome position: 62.26

GC content: 62.69

Gene sequence:

>855_bases
ATGCCCCCAGAAAACCAGCGACTAGCCGATCTTTTGCGCAACGAGCAGGACAGCGTGATCCAGGGATGGACGGCGGAGTA
CCAGGTCTATGCAGAGGGGAAAGCGCTGACCCACGATCTGATTTCCGAGCAGCGGGCGATCCTGCGGGCACTGGAAGCCG
GCATGCGTGGCGCCGGGGATGCCGCCCAGTTCAGAGCCGCGGCATCATGGACTGCGTTGCGAGAGACGCTGACGCGGCTA
TCCAGCGCGCGCGCCGCACAGGGCGAAACCGCCGACGTGACCAGTGGCTTCGTGCTGGCGCTCAAGCGGCCGATCTTCGA
AGCCCTGCAGCGGCAGGCTGGGGGTGTGGAGGACCAGATCAACGTCATCTGGGCTGCCTCGGACATTGTCGACCGCATGG
CGCAGTGGACTGTGTCCTCGTACCAGAAAACGCGCGAAGAGATCATCGTGCGTCAGCAGCAGGAGCTGATGGAACTGTCG
ACGCCTGTCATCAAGCTGTGGGAAGGAGTACTGGCGGTGCCCGTGATCGGAACGCTCGACAGCAGCCGCTCGCAGATGGT
CATGGAAACACTGCTGGAGCGGCTGGTGGAAACCGGCTCGGAACTGGCCATCATCGACATTACAGGGGTGCCTACCGTGG
ATACGCTGGTGGCGCAGCACCTGATCAAGACGGTGACCGCCATTCGATTGATGGGTGCCGAAAGCATCATCAGTGGTATC
CGCCCACAGATTGCACAAACCATTGTCCATCTGGGCATCGACCTGCAAGGCATCACTACCAAGTCCACCCTGGCCGATGC
GCTCGCCACCGCGATGCGCCTGACGGGACACACGGTGTCGCGCGGCGCTGCCTGA

Upstream 100 bases:

>100_bases
GCCGATAGTGCACACCCGTGATCTTTCCTAGAATGAAGTGATCCACTTGCCTGACGCAAGCTTGAGGCGGGTGCCTATCA
CATACTGACCCCGACACCCC

Downstream 100 bases:

>100_bases
GACGCAGAAACCGCCATGGAACGGATTCCAATCTTGCGGATGGGCAAGCACCTGCTCGTGACCATCCAGATCGATATGCA
GGACCAGACCGCTCTGATGT

Product: Sulfate transporter/antisigma-factor antagonist STAS

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MPPENQRLADLLRNEQDSVIQGWTAEYQVYAEGKALTHDLISEQRAILRALEAGMRGAGDAAQFRAAASWTALRETLTRL
SSARAAQGETADVTSGFVLALKRPIFEALQRQAGGVEDQINVIWAASDIVDRMAQWTVSSYQKTREEIIVRQQQELMELS
TPVIKLWEGVLAVPVIGTLDSSRSQMVMETLLERLVETGSELAIIDITGVPTVDTLVAQHLIKTVTAIRLMGAESIISGI
RPQIAQTIVHLGIDLQGITTKSTLADALATAMRLTGHTVSRGAA

Sequences:

>Translated_284_residues
MPPENQRLADLLRNEQDSVIQGWTAEYQVYAEGKALTHDLISEQRAILRALEAGMRGAGDAAQFRAAASWTALRETLTRL
SSARAAQGETADVTSGFVLALKRPIFEALQRQAGGVEDQINVIWAASDIVDRMAQWTVSSYQKTREEIIVRQQQELMELS
TPVIKLWEGVLAVPVIGTLDSSRSQMVMETLLERLVETGSELAIIDITGVPTVDTLVAQHLIKTVTAIRLMGAESIISGI
RPQIAQTIVHLGIDLQGITTKSTLADALATAMRLTGHTVSRGAA
>Mature_283_residues
PPENQRLADLLRNEQDSVIQGWTAEYQVYAEGKALTHDLISEQRAILRALEAGMRGAGDAAQFRAAASWTALRETLTRLS
SARAAQGETADVTSGFVLALKRPIFEALQRQAGGVEDQINVIWAASDIVDRMAQWTVSSYQKTREEIIVRQQQELMELST
PVIKLWEGVLAVPVIGTLDSSRSQMVMETLLERLVETGSELAIIDITGVPTVDTLVAQHLIKTVTAIRLMGAESIISGIR
PQIAQTIVHLGIDLQGITTKSTLADALATAMRLTGHTVSRGAA

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 30852; Mature: 30721

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPENQRLADLLRNEQDSVIQGWTAEYQVYAEGKALTHDLISEQRAILRALEAGMRGAGD
CCCCHHHHHHHHCCCCHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCC
AAQFRAAASWTALRETLTRLSSARAAQGETADVTSGFVLALKRPIFEALQRQAGGVEDQI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
NVIWAASDIVDRMAQWTVSSYQKTREEIIVRQQQELMELSTPVIKLWEGVLAVPVIGTLD
HEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SSRSQMVMETLLERLVETGSELAIIDITGVPTVDTLVAQHLIKTVTAIRLMGAESIISGI
CHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RPQIAQTIVHLGIDLQGITTKSTLADALATAMRLTGHTVSRGAA
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PPENQRLADLLRNEQDSVIQGWTAEYQVYAEGKALTHDLISEQRAILRALEAGMRGAGD
CCCHHHHHHHHCCCCHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCC
AAQFRAAASWTALRETLTRLSSARAAQGETADVTSGFVLALKRPIFEALQRQAGGVEDQI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
NVIWAASDIVDRMAQWTVSSYQKTREEIIVRQQQELMELSTPVIKLWEGVLAVPVIGTLD
HEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SSRSQMVMETLLERLVETGSELAIIDITGVPTVDTLVAQHLIKTVTAIRLMGAESIISGI
CHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RPQIAQTIVHLGIDLQGITTKSTLADALATAMRLTGHTVSRGAA
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]