Click here to switch to the map view.

The map label for this gene is fabD [H]

Identifier: 73538756

GI number: 73538756

Start: 1656478

End: 1657404

Strand: Direct

Name: fabD [H]

Synonym: Reut_B4931

Alternate gene names: 73538756

Gene position: 1656478-1657404 (Clockwise)

Preceding gene: 73538755

Following gene: 73538758

Centisome position: 60.76

GC content: 67.75

Gene sequence:

>927_bases
ATGAGCGTGCTGCTGACCTTTCCGGGCCAGGGCTCGCAGCGGGCCGGCATGCTCGCGGACCTGCCCGATCATCGGGCCGT
CGCCGCGGTGCTTGCGGAAGCTGCGGAGGTGCTGCAAACGCAGCCCGCCGACATGGATACCGCGTCGCGCCTGCAATCGA
CGGTGTGGGTACAGCTTTGCCTGCTGACGGCCGGCGTGGCCATGGCGCGCTGCCTGGCGGCAGAAGGTGGCCATGCCGAC
GCCGTTGCCGGACTTTCGATCGGTGCCTATGCGGCGGCCGTCAGTGCAGAGGTACTGCCATTCTCCGACGCACTGCGCAT
CGTCCGCCTGCGTGGCGAACTCATGGAGCAAGCCTATCCGAACGGCTACGGCATGACGGCGATTCTCGGCCTGGAGCGCA
TGCGGCTGGAACCGCTGGTGGCGCAGATTCACACACCGCAAACGCCGGTCTATCTCGCCAACTTCAATGCGCCCGCGCAG
ATCGTGATCGCTGGCAGCGTCCCGGCGATGGAAGCGGTGGCAGCGTTGGCAATCGCGTCGGGCGCACAGGCGGCGAAGCG
TGTCGCGATCCATGTACCTTCGCATTGCGCCCTGCTCGATGACGCCGCCGCCGAATTGGGCAAGGAAATGGCACACATCG
CCATGTCGCCACCGCGCCTGCGCTACTTCAGCGCGAGCCTTGCGCGCGAACTGCGCGACCCACGCCGGATCGCCGATGAC
CTGGCCCTCAACATGGCCGTCCCGGTGCGCTGGCACGAGACCATGCTGCTCGCGTACGCGACGGGTGCACGCGTGGTTAT
CGAAGCGCCGCCGGGTGATGTGCTGACGCGACTGGCCCAGCCCGTCTTCGCCGATGGCATCGTCATGGCGGCGGACAGGA
CGCGGGTCGATTCGCTGGCCGCGATCATGCGGCGCGGCCAGCCATAG

Upstream 100 bases:

>100_bases
GCGGCTTCTCGTTCCTCGAATGGCGGCGCACCGGCGGCAAGGTGCTGATGAAGACTGCGCACGGACCGAGGATGTGCGCC
CATCCGTGGCAGGCCGTGAC

Downstream 100 bases:

>100_bases
CTGACGACCGCTCAGGCGTGCCAGTCCTGCAGCGGATTGCACGCCATGTAACGCGGCGCCTCGCCAATGCCAAGGCGGGC
ACGCGCCGTGTCGAGCGATT

Product: acyl transferase region

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSVLLTFPGQGSQRAGMLADLPDHRAVAAVLAEAAEVLQTQPADMDTASRLQSTVWVQLCLLTAGVAMARCLAAEGGHAD
AVAGLSIGAYAAAVSAEVLPFSDALRIVRLRGELMEQAYPNGYGMTAILGLERMRLEPLVAQIHTPQTPVYLANFNAPAQ
IVIAGSVPAMEAVAALAIASGAQAAKRVAIHVPSHCALLDDAAAELGKEMAHIAMSPPRLRYFSASLARELRDPRRIADD
LALNMAVPVRWHETMLLAYATGARVVIEAPPGDVLTRLAQPVFADGIVMAADRTRVDSLAAIMRRGQP

Sequences:

>Translated_308_residues
MSVLLTFPGQGSQRAGMLADLPDHRAVAAVLAEAAEVLQTQPADMDTASRLQSTVWVQLCLLTAGVAMARCLAAEGGHAD
AVAGLSIGAYAAAVSAEVLPFSDALRIVRLRGELMEQAYPNGYGMTAILGLERMRLEPLVAQIHTPQTPVYLANFNAPAQ
IVIAGSVPAMEAVAALAIASGAQAAKRVAIHVPSHCALLDDAAAELGKEMAHIAMSPPRLRYFSASLARELRDPRRIADD
LALNMAVPVRWHETMLLAYATGARVVIEAPPGDVLTRLAQPVFADGIVMAADRTRVDSLAAIMRRGQP
>Mature_307_residues
SVLLTFPGQGSQRAGMLADLPDHRAVAAVLAEAAEVLQTQPADMDTASRLQSTVWVQLCLLTAGVAMARCLAAEGGHADA
VAGLSIGAYAAAVSAEVLPFSDALRIVRLRGELMEQAYPNGYGMTAILGLERMRLEPLVAQIHTPQTPVYLANFNAPAQI
VIAGSVPAMEAVAALAIASGAQAAKRVAIHVPSHCALLDDAAAELGKEMAHIAMSPPRLRYFSASLARELRDPRRIADDL
ALNMAVPVRWHETMLLAYATGARVVIEAPPGDVLTRLAQPVFADGIVMAADRTRVDSLAAIMRRGQP

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=303, Percent_Identity=27.0627062706271, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787334, Length=287, Percent_Identity=37.2822299651568, Blast_Score=141, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI71984332, Length=267, Percent_Identity=27.3408239700375, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24665753, Length=305, Percent_Identity=27.8688524590164, Blast_Score=85, Evalue=6e-17,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32494; Mature: 32363

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLLTFPGQGSQRAGMLADLPDHRAVAAVLAEAAEVLQTQPADMDTASRLQSTVWVQLC
CEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LLTAGVAMARCLAAEGGHADAVAGLSIGAYAAAVSAEVLPFSDALRIVRLRGELMEQAYP
HHHHHHHHHHHHHCCCCCCHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
NGYGMTAILGLERMRLEPLVAQIHTPQTPVYLANFNAPAQIVIAGSVPAMEAVAALAIAS
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHC
GAQAAKRVAIHVPSHCALLDDAAAELGKEMAHIAMSPPRLRYFSASLARELRDPRRIADD
CHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHH
LALNMAVPVRWHETMLLAYATGARVVIEAPPGDVLTRLAQPVFADGIVMAADRTRVDSLA
HHHHEEECEEEHHEEEEEEECCCEEEEECCCCHHHHHHHHHHHHCCEEEECCCHHHHHHH
AIMRRGQP
HHHHCCCC
>Mature Secondary Structure 
SVLLTFPGQGSQRAGMLADLPDHRAVAAVLAEAAEVLQTQPADMDTASRLQSTVWVQLC
EEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LLTAGVAMARCLAAEGGHADAVAGLSIGAYAAAVSAEVLPFSDALRIVRLRGELMEQAYP
HHHHHHHHHHHHHCCCCCCHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
NGYGMTAILGLERMRLEPLVAQIHTPQTPVYLANFNAPAQIVIAGSVPAMEAVAALAIAS
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHC
GAQAAKRVAIHVPSHCALLDDAAAELGKEMAHIAMSPPRLRYFSASLARELRDPRRIADD
CHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHH
LALNMAVPVRWHETMLLAYATGARVVIEAPPGDVLTRLAQPVFADGIVMAADRTRVDSLA
HHHHEEECEEEHHEEEEEEECCCEEEEECCCCHHHHHHHHHHHHCCEEEECCCHHHHHHH
AIMRRGQP
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]