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The map label for this gene is dnaJ [H]

Identifier: 73538551

GI number: 73538551

Start: 1425875

End: 1426840

Strand: Reverse

Name: dnaJ [H]

Synonym: Reut_B4726

Alternate gene names: 73538551

Gene position: 1426840-1425875 (Counterclockwise)

Preceding gene: 73538556

Following gene: 73538548

Centisome position: 52.34

GC content: 65.01

Gene sequence:

>966_bases
ATGGATAGCGACTACTACCGAGTACTCGGGGTTCGACGTGCGGCTTCACAGGCCGATATCCGCAATGCCTATCGCCGCCT
GGCCATGCGTTGGCATCCGGACAGGAATCCCGACACGGTCGAGCGTGCGGAAGCGGTCTTCAAGTCGCTGCAGCAAGCCT
ATGCGGTGCTGAAAGACCCGGTGGCCCGCGCTGCCTACGACGCGCAAGTGGCACAGCCGAGGCGCAATGACGGCCCTCCG
GCGGCGCCGGACACTGCGCACAACCCGGGTACACCGGGCGCGGACTACGTCTGCGAGACGACGATTCCGCTTGAAACAGC
CGTTCTCGGAGGCATTGCGTTGACGAGAGTCAGCGAGTCTCCGGCCTGTGTGCACTGTTCGGGAAAGGGGCAACAGGCTT
CGAGCTGCGCGACCTGTGAGGGCCGTGGTTCACTCGCCCGACGTTTCCGGCAGGTGCCATGCACTGACTGCAAGGGTGCG
GGTCAGCGAACGCGTCGTTGCGATGCCTGCCGGGGGCTCGGGACGACCCGGGTGGCAAAGCTGCTGCGCGTCACGGTTCC
CGCGCATACCAGAGATGGCACCGTGCTTCGCGCCAGGGGCCTCGGAGGGGAATCCGTCGACGGCGGGCCCAGGGGCAACC
TGCTTTGCAAAGTCAGTATTCGTGCAGACCGCGTCTTCCGCATGGACGGACTGGATCTTCAGCGCGAACTGAAGATCGAC
TTCGTGGTTGCCATCCTGGGCGGACAGGTGCCGTTGATGCGCTTCCGGAACTCCCTGGTGGTGGAGGTGCCGCCAATGAC
GCGCAGTGGCGCGCTGATCCGCATAGCGGGGCAGGGGCTGCAGGATCCAAAGCGCCGGCGGTCTGGAGACCTCGTGCTGA
AAGTCATGATCGATCTGCCGGCGAAGATGCGCATGCCCGACGAGCGGCAGCGCGCGGTGTTGCGCGAGATCGCTCGTGGA
TATTGA

Upstream 100 bases:

>100_bases
GCAATGTGCATCGATGCCGCGCCGGTGAAACAAGCCGCAGCCTCGGTCAGGTCGCCCCGGCGGCCCGGAAAACATCACCA
CGACGAGAACCAACTCAGGG

Downstream 100 bases:

>100_bases
TCGGGGCGAGGCCGCTTGCCGTTGCCCCTCATCCTTCGGCTGTGCGCGACGTCTTACCAGCGTTCCATGTAAGGGCGCAG
GTCCAGCTCAAAAGTCCAGG

Product: heat shock protein DnaJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MDSDYYRVLGVRRAASQADIRNAYRRLAMRWHPDRNPDTVERAEAVFKSLQQAYAVLKDPVARAAYDAQVAQPRRNDGPP
AAPDTAHNPGTPGADYVCETTIPLETAVLGGIALTRVSESPACVHCSGKGQQASSCATCEGRGSLARRFRQVPCTDCKGA
GQRTRRCDACRGLGTTRVAKLLRVTVPAHTRDGTVLRARGLGGESVDGGPRGNLLCKVSIRADRVFRMDGLDLQRELKID
FVVAILGGQVPLMRFRNSLVVEVPPMTRSGALIRIAGQGLQDPKRRRSGDLVLKVMIDLPAKMRMPDERQRAVLREIARG
Y

Sequences:

>Translated_321_residues
MDSDYYRVLGVRRAASQADIRNAYRRLAMRWHPDRNPDTVERAEAVFKSLQQAYAVLKDPVARAAYDAQVAQPRRNDGPP
AAPDTAHNPGTPGADYVCETTIPLETAVLGGIALTRVSESPACVHCSGKGQQASSCATCEGRGSLARRFRQVPCTDCKGA
GQRTRRCDACRGLGTTRVAKLLRVTVPAHTRDGTVLRARGLGGESVDGGPRGNLLCKVSIRADRVFRMDGLDLQRELKID
FVVAILGGQVPLMRFRNSLVVEVPPMTRSGALIRIAGQGLQDPKRRRSGDLVLKVMIDLPAKMRMPDERQRAVLREIARG
Y
>Mature_321_residues
MDSDYYRVLGVRRAASQADIRNAYRRLAMRWHPDRNPDTVERAEAVFKSLQQAYAVLKDPVARAAYDAQVAQPRRNDGPP
AAPDTAHNPGTPGADYVCETTIPLETAVLGGIALTRVSESPACVHCSGKGQQASSCATCEGRGSLARRFRQVPCTDCKGA
GQRTRRCDACRGLGTTRVAKLLRVTVPAHTRDGTVLRARGLGGESVDGGPRGNLLCKVSIRADRVFRMDGLDLQRELKID
FVVAILGGQVPLMRFRNSLVVEVPPMTRSGALIRIAGQGLQDPKRRRSGDLVLKVMIDLPAKMRMPDERQRAVLREIARG
Y

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG0484

COG function: function code O; DnaJ-class molecular chaperone with C-terminal Zn finger domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI194328760, Length=342, Percent_Identity=26.9005847953216, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI194328758, Length=342, Percent_Identity=26.9005847953216, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI205360840, Length=358, Percent_Identity=27.9329608938547, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI205360838, Length=358, Percent_Identity=27.9329608938547, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI4504511, Length=333, Percent_Identity=27.027027027027, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI5031741, Length=341, Percent_Identity=26.3929618768328, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI7706495, Length=341, Percent_Identity=27.2727272727273, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI23503241, Length=94, Percent_Identity=44.6808510638298, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI4885495, Length=64, Percent_Identity=56.25, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI17388799, Length=64, Percent_Identity=56.25, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI27151736, Length=63, Percent_Identity=53.968253968254, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI88501736, Length=63, Percent_Identity=53.968253968254, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI21553335, Length=64, Percent_Identity=50, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI68077166, Length=63, Percent_Identity=52.3809523809524, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI68077168, Length=63, Percent_Identity=52.3809523809524, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI47777312, Length=64, Percent_Identity=53.125, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI217035105, Length=68, Percent_Identity=50, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI194328762, Length=297, Percent_Identity=24.2424242424242, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI56687498, Length=67, Percent_Identity=50.7462686567164, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI56549115, Length=67, Percent_Identity=43.2835820895522, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI201862518, Length=67, Percent_Identity=43.2835820895522, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI6631085, Length=67, Percent_Identity=46.2686567164179, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI201862587, Length=67, Percent_Identity=43.2835820895522, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI194306642, Length=64, Percent_Identity=50, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI194306640, Length=64, Percent_Identity=50, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI5453690, Length=67, Percent_Identity=47.7611940298507, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786197, Length=348, Percent_Identity=31.8965517241379, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1787235, Length=317, Percent_Identity=28.391167192429, Blast_Score=108, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17553096, Length=345, Percent_Identity=23.768115942029, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17553098, Length=352, Percent_Identity=23.8636363636364, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17507263, Length=340, Percent_Identity=26.1764705882353, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI212645553, Length=340, Percent_Identity=27.9411764705882, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17554644, Length=73, Percent_Identity=47.945205479452, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17554874, Length=63, Percent_Identity=49.2063492063492, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17563890, Length=240, Percent_Identity=23.3333333333333, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17534355, Length=67, Percent_Identity=41.7910447761194, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324265, Length=355, Percent_Identity=28.7323943661972, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6324103, Length=80, Percent_Identity=46.25, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323870, Length=224, Percent_Identity=25.8928571428571, Blast_Score=73, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6320888, Length=66, Percent_Identity=43.9393939393939, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161077138, Length=66, Percent_Identity=46.969696969697, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24654066, Length=64, Percent_Identity=46.875, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24654070, Length=64, Percent_Identity=46.875, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24654068, Length=64, Percent_Identity=46.875, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24654072, Length=64, Percent_Identity=46.875, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24762799, Length=68, Percent_Identity=48.5294117647059, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI85726398, Length=356, Percent_Identity=24.1573033707865, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI19920464, Length=327, Percent_Identity=24.7706422018349, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI20129487, Length=333, Percent_Identity=25.8258258258258, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24584014, Length=333, Percent_Identity=25.8258258258258, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24641698, Length=90, Percent_Identity=40, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24641696, Length=90, Percent_Identity=40, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI18858081, Length=68, Percent_Identity=44.1176470588235, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24668492, Length=82, Percent_Identity=40.2439024390244, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24658562, Length=67, Percent_Identity=43.2835820895522, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24658555, Length=67, Percent_Identity=43.2835820895522, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]

EC number: NA

Molecular weight: Translated: 35096; Mature: 35096

Theoretical pI: Translated: 10.54; Mature: 10.54

Prosite motif: PS00636 DNAJ_1 ; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSDYYRVLGVRRAASQADIRNAYRRLAMRWHPDRNPDTVERAEAVFKSLQQAYAVLKDP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VARAAYDAQVAQPRRNDGPPAAPDTAHNPGTPGADYVCETTIPLETAVLGGIALTRVSES
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHCCHHEEEECCC
PACVHCSGKGQQASSCATCEGRGSLARRFRQVPCTDCKGAGQRTRRCDACRGLGTTRVAK
CCEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHHHH
LLRVTVPAHTRDGTVLRARGLGGESVDGGPRGNLLCKVSIRADRVFRMDGLDLQRELKID
HHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCEEEEECCCCCHHHHHHE
FVVAILGGQVPLMRFRNSLVVEVPPMTRSGALIRIAGQGLQDPKRRRSGDLVLKVMIDLP
EEEEECCCCCHHHHHCCCEEEEECCCCCCCCEEEEECCCCCCHHHHCCCCEEEEEEECCC
AKMRMPDERQRAVLREIARGY
HHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MDSDYYRVLGVRRAASQADIRNAYRRLAMRWHPDRNPDTVERAEAVFKSLQQAYAVLKDP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VARAAYDAQVAQPRRNDGPPAAPDTAHNPGTPGADYVCETTIPLETAVLGGIALTRVSES
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHCCHHEEEECCC
PACVHCSGKGQQASSCATCEGRGSLARRFRQVPCTDCKGAGQRTRRCDACRGLGTTRVAK
CCEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHHHH
LLRVTVPAHTRDGTVLRARGLGGESVDGGPRGNLLCKVSIRADRVFRMDGLDLQRELKID
HHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCEEEEECCCCCHHHHHHE
FVVAILGGQVPLMRFRNSLVVEVPPMTRSGALIRIAGQGLQDPKRRRSGDLVLKVMIDLP
EEEEECCCCCHHHHHCCCEEEEECCCCCCCCEEEEECCCCCCHHHHCCCCEEEEEEECCC
AKMRMPDERQRAVLREIARGY
HHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA