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The map label for this gene is linE [H]

Identifier: 73538522

GI number: 73538522

Start: 1394648

End: 1395607

Strand: Reverse

Name: linE [H]

Synonym: Reut_B4696

Alternate gene names: 73538522

Gene position: 1395607-1394648 (Counterclockwise)

Preceding gene: 73538523

Following gene: 73538521

Centisome position: 51.19

GC content: 61.98

Gene sequence:

>960_bases
ATGACCCAAGCTACACCATCCATCCAGCGCCATCACCACATCACGCTGAGCGTTGGCACAGCCCAGGAAGACTATGACTT
CCATACCAAGGTGCTCTCTCTCAAGAGCGTCAAGAAGACTTTGATCTATGACGGCGGCACGCCGTTCTACCACCTCTACT
ACGGCAATGATGTCGGCGAAGAAAGCACGCTGATCACCTGCTTCCCGGTGGCCCATTTCGGCCGCAAGGGCACGCGCGGT
ACGGGTCAGATCGGCAGCCTGGCGCTCTCGGTGCCCGCGTCCGCCATTCCGTTCTGGGACAAGCGCCTGCGCGACCACGG
TTTCGAAGTCCGCCGTTCCGAGCGGTTCGGCGAGCAGGTGCTGGCGTTCGCGCATCCTTGCGGCATCGAGTACGAGCTGA
TCGGTATCGCCGATGATGCACGCAAGCCGTATTCCAACGGCGAAGTTCCTGCCGAGCTGGCGATCCGCGGGCTTCACACC
ATCGCGGTGAATGTGCGCGAGATGGAGCCGTCGCAGGAATTCATGGATGCCGGCTGGTCGGCGCGTGAAGTGGCGCGCGA
CGGCAAGTACGCGCGCTATGCATTCGGGGAGGGCGGCTCCGGTAAGTTTGTGGACTATGCATTGGAAACGGCCATGCCGC
AGGCTAGCTGGACCTATGGCTCCGGCACGGTCCACCACTGTGCGTTCCAGGTCGACGACCATGCTGCGCAGGACTACTTC
AAGCGCAGGCTTGAGGGCCTTGGCTTCACCGACACGTCGGAACGCAAGGATCGCGGGTATTTCGAGTCGATCTACGTACG
CACCCCGAGCGGGGCCCTGTTCGAGGCTACGGTGTCCAAGCCTCACGCTTTCCTGATCGACGAACCGTACGAAACGCTTG
GCGCCGAGGTGCAGGTTGCGCCGCAGTTCGCCAGCCAGCGCGAAAGCATCCTGCGCTCGCTGGAAACGCTGAAGTACTGA

Upstream 100 bases:

>100_bases
CCATGACGGGCGCGCTTTCGCCCACCTGAGCCAGGACGACGGCGCGAGGCCCGCGACGGGCATCGTGCCAGCGGGGCACA
ACAAACCATTGGAGACAATC

Downstream 100 bases:

>100_bases
ACCCCTCGACGGGCCACGCCATCCTGGGTCGTGGCTTGAACGAATGCCTGATACGGCAGGAACTGTATGCCAGAACTCAA
CCCACACCTCGCTGCGCCAC

Product: glyoxalase/bleomycin resistance protein/dioxygenase

Products: NA

Alternate protein names: Hydroquinone meta-cleavage dioxygenase [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MTQATPSIQRHHHITLSVGTAQEDYDFHTKVLSLKSVKKTLIYDGGTPFYHLYYGNDVGEESTLITCFPVAHFGRKGTRG
TGQIGSLALSVPASAIPFWDKRLRDHGFEVRRSERFGEQVLAFAHPCGIEYELIGIADDARKPYSNGEVPAELAIRGLHT
IAVNVREMEPSQEFMDAGWSAREVARDGKYARYAFGEGGSGKFVDYALETAMPQASWTYGSGTVHHCAFQVDDHAAQDYF
KRRLEGLGFTDTSERKDRGYFESIYVRTPSGALFEATVSKPHAFLIDEPYETLGAEVQVAPQFASQRESILRSLETLKY

Sequences:

>Translated_319_residues
MTQATPSIQRHHHITLSVGTAQEDYDFHTKVLSLKSVKKTLIYDGGTPFYHLYYGNDVGEESTLITCFPVAHFGRKGTRG
TGQIGSLALSVPASAIPFWDKRLRDHGFEVRRSERFGEQVLAFAHPCGIEYELIGIADDARKPYSNGEVPAELAIRGLHT
IAVNVREMEPSQEFMDAGWSAREVARDGKYARYAFGEGGSGKFVDYALETAMPQASWTYGSGTVHHCAFQVDDHAAQDYF
KRRLEGLGFTDTSERKDRGYFESIYVRTPSGALFEATVSKPHAFLIDEPYETLGAEVQVAPQFASQRESILRSLETLKY
>Mature_318_residues
TQATPSIQRHHHITLSVGTAQEDYDFHTKVLSLKSVKKTLIYDGGTPFYHLYYGNDVGEESTLITCFPVAHFGRKGTRGT
GQIGSLALSVPASAIPFWDKRLRDHGFEVRRSERFGEQVLAFAHPCGIEYELIGIADDARKPYSNGEVPAELAIRGLHTI
AVNVREMEPSQEFMDAGWSAREVARDGKYARYAFGEGGSGKFVDYALETAMPQASWTYGSGTVHHCAFQVDDHAAQDYFK
RRLEGLGFTDTSERKDRGYFESIYVRTPSGALFEATVSKPHAFLIDEPYETLGAEVQVAPQFASQRESILRSLETLKY

Specific function: Cleaves aromatic rings with two hydroxyl groups at para positions. Is involved in the degradation of both chlorohydroquinone (CHQ) and hydroquinone (HQ), producing maleylacetate and gamma-hydroxymuconic semialdehyde, respectively, with consumption of O(2)

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the extradiol ring-cleavage dioxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: NA

Molecular weight: Translated: 35607; Mature: 35476

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQATPSIQRHHHITLSVGTAQEDYDFHTKVLSLKSVKKTLIYDGGTPFYHLYYGNDVGE
CCCCCCCCHHCEEEEEEECCCCCCCCHHHHHHHHHHHHHHEEECCCCCEEEEEECCCCCC
ESTLITCFPVAHFGRKGTRGTGQIGSLALSVPASAIPFWDKRLRDHGFEVRRSERFGEQV
CCEEEEEEEHHHCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
LAFAHPCGIEYELIGIADDARKPYSNGEVPAELAIRGLHTIAVNVREMEPSQEFMDAGWS
HHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHEEEEEEEEEECCCCHHHHHHCCCC
AREVARDGKYARYAFGEGGSGKFVDYALETAMPQASWTYGSGTVHHCAFQVDDHAAQDYF
HHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCCCCCEECCCCCEEEEEEEECCHHHHHHH
KRRLEGLGFTDTSERKDRGYFESIYVRTPSGALFEATVSKPHAFLIDEPYETLGAEVQVA
HHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCEEEEEECCHHHCCCEEEEC
PQFASQRESILRSLETLKY
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQATPSIQRHHHITLSVGTAQEDYDFHTKVLSLKSVKKTLIYDGGTPFYHLYYGNDVGE
CCCCCCCHHCEEEEEEECCCCCCCCHHHHHHHHHHHHHHEEECCCCCEEEEEECCCCCC
ESTLITCFPVAHFGRKGTRGTGQIGSLALSVPASAIPFWDKRLRDHGFEVRRSERFGEQV
CCEEEEEEEHHHCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
LAFAHPCGIEYELIGIADDARKPYSNGEVPAELAIRGLHTIAVNVREMEPSQEFMDAGWS
HHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHEEEEEEEEEECCCCHHHHHHCCCC
AREVARDGKYARYAFGEGGSGKFVDYALETAMPQASWTYGSGTVHHCAFQVDDHAAQDYF
HHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCCCCCEECCCCCEEEEEEEECCHHHHHHH
KRRLEGLGFTDTSERKDRGYFESIYVRTPSGALFEATVSKPHAFLIDEPYETLGAEVQVA
HHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCEEEEEECCHHHCCCEEEEC
PQFASQRESILRSLETLKY
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10542173 [H]