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The map label for this gene is mmgC [H]

Identifier: 73538087

GI number: 73538087

Start: 913993

End: 915126

Strand: Direct

Name: mmgC [H]

Synonym: Reut_B4257

Alternate gene names: 73538087

Gene position: 913993-915126 (Clockwise)

Preceding gene: 73538085

Following gene: 73538088

Centisome position: 33.53

GC content: 67.46

Gene sequence:

>1134_bases
ATGCACAGCGACTACACCGAAGAGCAAATCATGATCCGCGACTCCGCGCGCGCCTTTGCAAGCGAACGGCTCGCTGCCGG
CGCCGCCGAGTGGGACCGCGCCGGCCGGCTGCCCGAAGAGGTCGTGGCCGAGATGGGCGCGCTAGGCCTGCTCGGCATGA
TCGTGCCCGAGGAATGGGGCGGTACCTACACCGACTACGTGGCCTACGCGCTCGCCATCGAGGAAATCGCTGCCGGTTGC
GCCGCCTGCGCAACGCTCATGAGCGTGCACAACTCGGTCGGTTGCGGGCCGATCCTGCACTACGGCACCGAGGCACAGAA
GCAGCGCTACCTGGCGCGCCTGGCCAGTGGCGAACTGATCGGCGCGTTCTGCCTGACCGAACCGCAGGCCGGCTCCGAAG
CCCACAACCTGCGCACGCGCGCCCGGCCCTCTGAGCGCGGCTGGGTGCTGAACGGCAGCAAGCAGTTCGTCACCAACGGC
CAGCGCGCCGGCGTGGCGGTGGTCTTTGCCGCGACAGAGCCCGAACGCGGCAAGAAAGGGATCTCCGCGTTCCTGGTGCC
GACCGACACGCCGGGCTTCATCGTCCATGCGCCGGAGAAGAAGCTTGGCATCCGCGCGTCCGACACCTGTGCCATCACGC
TTGAAGATTGCGAAGTGCCGGCCGACGCGCTGCTCGGCGAGCCCGGCGAGGGCCTGCGCATCGCGTTGTCCAACCTCGAA
GGCGGGCGCATCGGCATTGCGGCGCAGGCCATCGGCATTGCCCGCTCGGCATTCGAAGCCGCGTGCCGCTACGCATCCGA
GCGTGTGCAGTTCGGCCGGCCACTGCGCGAGCACCCGCCCATCGCGAACATGCTTGCCGACATGGCGACAGAGTTGAACG
CCGCGCGACTGCTGGTGCATCGCGCCGCACGCATGCGTACGCAAGGGTTGCCGTGCCTGTCGGAAGCATCGCAGGCAAAG
CTCTATGCGTCGGAACTCGCCGAACGCGTCTGTTCCAAGGCGCTGCAGATCCATGGCGGCTATGGCTACCTCGAGGACTA
CCCCGTCGAGCGCCACTACCGCGACGCCCGAATCACCCAGATCTATGAAGGCACCAGCGAGATCCAGCGCATGCTGATCG
CGCGCAGCCTGTAA

Upstream 100 bases:

>100_bases
GCGGATTTTGGCATAGGAGCCGCGGCAGGCGGTTTCTACACTGCGCCTGTTCACCAGAAAACCATCCGAAGACTCCTTTA
TCGCGCGCCGCGCCCCTGCC

Downstream 100 bases:

>100_bases
CACCCCGCCCTATTGAAGCTGCCTGACTTGCATCCCAATCCAGAACCGACCGGAGACATCATGAGTGCACTGCCCCAGAC
CGCCAACGCCGTTCCGTCCG

Product: butyryl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MHSDYTEEQIMIRDSARAFASERLAAGAAEWDRAGRLPEEVVAEMGALGLLGMIVPEEWGGTYTDYVAYALAIEEIAAGC
AACATLMSVHNSVGCGPILHYGTEAQKQRYLARLASGELIGAFCLTEPQAGSEAHNLRTRARPSERGWVLNGSKQFVTNG
QRAGVAVVFAATEPERGKKGISAFLVPTDTPGFIVHAPEKKLGIRASDTCAITLEDCEVPADALLGEPGEGLRIALSNLE
GGRIGIAAQAIGIARSAFEAACRYASERVQFGRPLREHPPIANMLADMATELNAARLLVHRAARMRTQGLPCLSEASQAK
LYASELAERVCSKALQIHGGYGYLEDYPVERHYRDARITQIYEGTSEIQRMLIARSL

Sequences:

>Translated_377_residues
MHSDYTEEQIMIRDSARAFASERLAAGAAEWDRAGRLPEEVVAEMGALGLLGMIVPEEWGGTYTDYVAYALAIEEIAAGC
AACATLMSVHNSVGCGPILHYGTEAQKQRYLARLASGELIGAFCLTEPQAGSEAHNLRTRARPSERGWVLNGSKQFVTNG
QRAGVAVVFAATEPERGKKGISAFLVPTDTPGFIVHAPEKKLGIRASDTCAITLEDCEVPADALLGEPGEGLRIALSNLE
GGRIGIAAQAIGIARSAFEAACRYASERVQFGRPLREHPPIANMLADMATELNAARLLVHRAARMRTQGLPCLSEASQAK
LYASELAERVCSKALQIHGGYGYLEDYPVERHYRDARITQIYEGTSEIQRMLIARSL
>Mature_377_residues
MHSDYTEEQIMIRDSARAFASERLAAGAAEWDRAGRLPEEVVAEMGALGLLGMIVPEEWGGTYTDYVAYALAIEEIAAGC
AACATLMSVHNSVGCGPILHYGTEAQKQRYLARLASGELIGAFCLTEPQAGSEAHNLRTRARPSERGWVLNGSKQFVTNG
QRAGVAVVFAATEPERGKKGISAFLVPTDTPGFIVHAPEKKLGIRASDTCAITLEDCEVPADALLGEPGEGLRIALSNLE
GGRIGIAAQAIGIARSAFEAACRYASERVQFGRPLREHPPIANMLADMATELNAARLLVHRAARMRTQGLPCLSEASQAK
LYASELAERVCSKALQIHGGYGYLEDYPVERHYRDARITQIYEGTSEIQRMLIARSL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=382, Percent_Identity=49.4764397905759, Blast_Score=358, Evalue=3e-99,
Organism=Homo sapiens, GI4501859, Length=373, Percent_Identity=42.0911528150134, Blast_Score=308, Evalue=7e-84,
Organism=Homo sapiens, GI4557231, Length=375, Percent_Identity=37.8666666666667, Blast_Score=254, Evalue=8e-68,
Organism=Homo sapiens, GI187960098, Length=375, Percent_Identity=37.8666666666667, Blast_Score=254, Evalue=8e-68,
Organism=Homo sapiens, GI21361497, Length=351, Percent_Identity=41.3105413105413, Blast_Score=253, Evalue=3e-67,
Organism=Homo sapiens, GI7656849, Length=374, Percent_Identity=36.8983957219251, Blast_Score=243, Evalue=2e-64,
Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=33.5106382978723, Blast_Score=235, Evalue=6e-62,
Organism=Homo sapiens, GI4501857, Length=376, Percent_Identity=34.3085106382979, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI226958414, Length=341, Percent_Identity=33.4310850439883, Blast_Score=221, Evalue=9e-58,
Organism=Homo sapiens, GI76496475, Length=335, Percent_Identity=37.910447761194, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI4557235, Length=335, Percent_Identity=37.910447761194, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI4503943, Length=387, Percent_Identity=32.8165374677003, Blast_Score=175, Evalue=5e-44,
Organism=Homo sapiens, GI7669494, Length=373, Percent_Identity=32.9758713136729, Blast_Score=165, Evalue=8e-41,
Organism=Homo sapiens, GI211971008, Length=368, Percent_Identity=30.7065217391304, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI48976061, Length=368, Percent_Identity=30.7065217391304, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI38505218, Length=357, Percent_Identity=28.8515406162465, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI87081958, Length=380, Percent_Identity=31.3157894736842, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI1786223, Length=371, Percent_Identity=29.1105121293801, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI87081702, Length=370, Percent_Identity=28.1081081081081, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI87082384, Length=298, Percent_Identity=28.8590604026846, Blast_Score=93, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17506239, Length=370, Percent_Identity=38.3783783783784, Blast_Score=272, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17508101, Length=370, Percent_Identity=38.1081081081081, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI17569725, Length=377, Percent_Identity=37.6657824933687, Blast_Score=264, Evalue=5e-71,
Organism=Caenorhabditis elegans, GI17534899, Length=381, Percent_Identity=37.5328083989501, Blast_Score=259, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI17538396, Length=374, Percent_Identity=34.7593582887701, Blast_Score=250, Evalue=9e-67,
Organism=Caenorhabditis elegans, GI17570075, Length=380, Percent_Identity=35.7894736842105, Blast_Score=248, Evalue=4e-66,
Organism=Caenorhabditis elegans, GI17533517, Length=369, Percent_Identity=35.230352303523, Blast_Score=229, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI71985184, Length=350, Percent_Identity=36.2857142857143, Blast_Score=219, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI71990804, Length=293, Percent_Identity=38.5665529010239, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17534353, Length=380, Percent_Identity=33.4210526315789, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17551932, Length=379, Percent_Identity=31.1345646437995, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17505929, Length=379, Percent_Identity=30.6068601583113, Blast_Score=176, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI32563615, Length=257, Percent_Identity=36.1867704280156, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI71985192, Length=285, Percent_Identity=35.0877192982456, Blast_Score=171, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI71982178, Length=274, Percent_Identity=30.2919708029197, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17531909, Length=241, Percent_Identity=31.9502074688797, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17531913, Length=179, Percent_Identity=32.9608938547486, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17562446, Length=288, Percent_Identity=29.1666666666667, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI86563381, Length=330, Percent_Identity=26.0606060606061, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI86563383, Length=330, Percent_Identity=26.0606060606061, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356377, Length=375, Percent_Identity=48, Blast_Score=354, Evalue=6e-98,
Organism=Drosophila melanogaster, GI24646207, Length=372, Percent_Identity=43.8172043010753, Blast_Score=305, Evalue=4e-83,
Organism=Drosophila melanogaster, GI24666513, Length=372, Percent_Identity=38.7096774193548, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24660351, Length=375, Percent_Identity=38.1333333333333, Blast_Score=262, Evalue=3e-70,
Organism=Drosophila melanogaster, GI281363737, Length=359, Percent_Identity=36.7688022284123, Blast_Score=222, Evalue=3e-58,
Organism=Drosophila melanogaster, GI21355753, Length=377, Percent_Identity=34.4827586206897, Blast_Score=215, Evalue=3e-56,
Organism=Drosophila melanogaster, GI19920834, Length=381, Percent_Identity=32.2834645669291, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI281365206, Length=278, Percent_Identity=29.136690647482, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24585193, Length=278, Percent_Identity=29.136690647482, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24585195, Length=278, Percent_Identity=29.136690647482, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24585191, Length=278, Percent_Identity=29.136690647482, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 40704; Mature: 40704

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSDYTEEQIMIRDSARAFASERLAAGAAEWDRAGRLPEEVVAEMGALGLLGMIVPEEWG
CCCCCCCCCEEEHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC
GTYTDYVAYALAIEEIAAGCAACATLMSVHNSVGCGPILHYGTEAQKQRYLARLASGELI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHCCCEE
GAFCLTEPQAGSEAHNLRTRARPSERGWVLNGSKQFVTNGQRAGVAVVFAATEPERGKKG
EEEEECCCCCCCHHHHHHHHCCCCCCCEEECCCHHHHCCCCCCCEEEEEEECCCCCCCCC
ISAFLVPTDTPGFIVHAPEKKLGIRASDTCAITLEDCEVPADALLGEPGEGLRIALSNLE
CEEEEEECCCCCEEEECCCHHHCCCCCCEEEEEECCCCCCHHHHCCCCCCCEEEEEECCC
GGRIGIAAQAIGIARSAFEAACRYASERVQFGRPLREHPPIANMLADMATELNAARLLVH
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHH
RAARMRTQGLPCLSEASQAKLYASELAERVCSKALQIHGGYGYLEDYPVERHYRDARITQ
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHCHHHHHH
IYEGTSEIQRMLIARSL
HHCCHHHHHHHHHHHCC
>Mature Secondary Structure
MHSDYTEEQIMIRDSARAFASERLAAGAAEWDRAGRLPEEVVAEMGALGLLGMIVPEEWG
CCCCCCCCCEEEHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC
GTYTDYVAYALAIEEIAAGCAACATLMSVHNSVGCGPILHYGTEAQKQRYLARLASGELI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHCCCEE
GAFCLTEPQAGSEAHNLRTRARPSERGWVLNGSKQFVTNGQRAGVAVVFAATEPERGKKG
EEEEECCCCCCCHHHHHHHHCCCCCCCEEECCCHHHHCCCCCCCEEEEEEECCCCCCCCC
ISAFLVPTDTPGFIVHAPEKKLGIRASDTCAITLEDCEVPADALLGEPGEGLRIALSNLE
CEEEEEECCCCCEEEECCCHHHCCCCCCEEEEEECCCCCCHHHHCCCCCCCEEEEEECCC
GGRIGIAAQAIGIARSAFEAACRYASERVQFGRPLREHPPIANMLADMATELNAARLLVH
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHH
RAARMRTQGLPCLSEASQAKLYASELAERVCSKALQIHGGYGYLEDYPVERHYRDARITQ
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHCHHHHHH
IYEGTSEIQRMLIARSL
HHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]