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The map label for this gene is ttuB [H]

Identifier: 73538050

GI number: 73538050

Start: 860400

End: 861722

Strand: Direct

Name: ttuB [H]

Synonym: Reut_B4220

Alternate gene names: 73538050

Gene position: 860400-861722 (Clockwise)

Preceding gene: 73538049

Following gene: 73538052

Centisome position: 31.56

GC content: 63.95

Gene sequence:

>1323_bases
ATGAGCAATCTGGCCTCAGGGGCGATTGCGGCCCCCGCTTACGCCGCGCACGAAGAAGACGCGCTGTATCGCAAGATCTG
GCTGCGCCTGATCCCGTTCCTGTTCGTGTGTTACGTGGTGTCATTCCTGGACCGCATCAACATCGGCTTTGCGCAGTTGC
AGATGAAGCAGGATCTCGGCTTCAGCGATGCCATGTACGGCCTCGGCGCGGCGGTCTTCTACGTCGGCTACGTGCTGTGC
GAAGTGCCCAGCAACATGCTGCTCGCACGCTTCGGTGCGCGCCGCACGTTTACGCGCATCATGGTGCTGTGGGGCGTGGC
ATCGGTCGGCATGATGGCGGTGTCCTCGCCGACGCAGTTCTATACGCTGCGCTTCCTGCTAGGCGTATTCGAGGCCGGTT
TCTTTCCCGGCATCGTGCTCTACCTGACGTACTGGTTTCCCGCAAAGCGCCGCGCCGCCGTCATGGCGATCTTCTTCGCG
GGCGTGGCGATCGCAGGTGTGCTGGGCGGACTGGTGTCCGGCTGGATCATGCGCGACATGGCCGGCGTGTTCGGCATGCA
GGGCTGGAAATGGATGTTCGCGATCGAAGGTGCGCCGGCCATCGTGCTCGGCGTGATCGCCGCGTTCTTCCTGGTCGATG
AGCCGCGCCAGGCAAGCTGGCTCAGCGACGGCGAAAAGGCGTTCCTGGAGCGTGCCCGCGCGCAGGATCACGGCGTCAAG
GCGCATTCGCTGCAGGCGCTGCTGCAGGTGCTGCGCAACCCGCGCGTGTACCTGTTCGCGTTCATCTATTTTTCGCTGAC
CTGTGGCTCGCTGGCGCTGAGCTTCTGGATGCCGCTGATGATCCGAGACTTCGGCATTACTGATGTCGTTTCCATCAGCC
TCTATTCGGTCGTGCCCAATGCGGTTGGCGCGGTTGGCCTGATCCTGATCGCGCGGCACTCGGACCGCAGCGGTGAACGC
CACCGGCATTTCCTGCTGTGTACGGTCGGCGGCGCACTGGCGCTGGCTGCGCTCACGTTGCACCTGCAGAGCCTGGCGGC
GATGCTGGCGATCCTGTCCATGGCCGCAGTACTGATCTTTGCCGCACTGCCGGTGTTCTGGTCGCTGCCGCCGTCGCATC
TGCCCGCAAGCGGCGCCGCAGCCGGCATCGCCTTTATCAGCAGCGTCGGCATCACGAGCGGCATTGTCAGCCCATGGGTG
ATCGGCCAGATCAAGGTTCAGACAGGAAGCCTCGACAATGCGCTGTACCTGCTGGCGGCCTTGCTGGTGGCAAGCGGAAT
GTCGATGTGGCTTGGCGTGCCGCGCCAGGCCGAGCACGCTTGA

Upstream 100 bases:

>100_bases
CGGGCACGCCGCGCGCGTGCCCCACCCCTTCCCGCACCGACCCGTTGCGAAGGCGTAGAAAACGCCGGCGCGGGCGGCGC
TCACACCGGAGACAAAGCAA

Downstream 100 bases:

>100_bases
CGGCCGGCACGCTGCATTCAACTACGCCCGACGGGAAGCCATCGGGCGCTTGCCATCTCAGTGCGGATGGCTGCACGGAA
TCACTGCGGCAATCTCCTCG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSNLASGAIAAPAYAAHEEDALYRKIWLRLIPFLFVCYVVSFLDRINIGFAQLQMKQDLGFSDAMYGLGAAVFYVGYVLC
EVPSNMLLARFGARRTFTRIMVLWGVASVGMMAVSSPTQFYTLRFLLGVFEAGFFPGIVLYLTYWFPAKRRAAVMAIFFA
GVAIAGVLGGLVSGWIMRDMAGVFGMQGWKWMFAIEGAPAIVLGVIAAFFLVDEPRQASWLSDGEKAFLERARAQDHGVK
AHSLQALLQVLRNPRVYLFAFIYFSLTCGSLALSFWMPLMIRDFGITDVVSISLYSVVPNAVGAVGLILIARHSDRSGER
HRHFLLCTVGGALALAALTLHLQSLAAMLAILSMAAVLIFAALPVFWSLPPSHLPASGAAAGIAFISSVGITSGIVSPWV
IGQIKVQTGSLDNALYLLAALLVASGMSMWLGVPRQAEHA

Sequences:

>Translated_440_residues
MSNLASGAIAAPAYAAHEEDALYRKIWLRLIPFLFVCYVVSFLDRINIGFAQLQMKQDLGFSDAMYGLGAAVFYVGYVLC
EVPSNMLLARFGARRTFTRIMVLWGVASVGMMAVSSPTQFYTLRFLLGVFEAGFFPGIVLYLTYWFPAKRRAAVMAIFFA
GVAIAGVLGGLVSGWIMRDMAGVFGMQGWKWMFAIEGAPAIVLGVIAAFFLVDEPRQASWLSDGEKAFLERARAQDHGVK
AHSLQALLQVLRNPRVYLFAFIYFSLTCGSLALSFWMPLMIRDFGITDVVSISLYSVVPNAVGAVGLILIARHSDRSGER
HRHFLLCTVGGALALAALTLHLQSLAAMLAILSMAAVLIFAALPVFWSLPPSHLPASGAAAGIAFISSVGITSGIVSPWV
IGQIKVQTGSLDNALYLLAALLVASGMSMWLGVPRQAEHA
>Mature_439_residues
SNLASGAIAAPAYAAHEEDALYRKIWLRLIPFLFVCYVVSFLDRINIGFAQLQMKQDLGFSDAMYGLGAAVFYVGYVLCE
VPSNMLLARFGARRTFTRIMVLWGVASVGMMAVSSPTQFYTLRFLLGVFEAGFFPGIVLYLTYWFPAKRRAAVMAIFFAG
VAIAGVLGGLVSGWIMRDMAGVFGMQGWKWMFAIEGAPAIVLGVIAAFFLVDEPRQASWLSDGEKAFLERARAQDHGVKA
HSLQALLQVLRNPRVYLFAFIYFSLTCGSLALSFWMPLMIRDFGITDVVSISLYSVVPNAVGAVGLILIARHSDRSGERH
RHFLLCTVGGALALAALTLHLQSLAAMLAILSMAAVLIFAALPVFWSLPPSHLPASGAAAGIAFISSVGITSGIVSPWVI
GQIKVQTGSLDNALYLLAALLVASGMSMWLGVPRQAEHA

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=392, Percent_Identity=37.2448979591837, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1789152, Length=425, Percent_Identity=23.5294117647059, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI2367379, Length=353, Percent_Identity=24.929178470255, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082320, Length=229, Percent_Identity=27.0742358078603, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789515, Length=418, Percent_Identity=25.1196172248804, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI2367193, Length=268, Percent_Identity=22.3880597014925, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322025, Length=219, Percent_Identity=30.5936073059361, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6321698, Length=321, Percent_Identity=23.98753894081, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6322612, Length=280, Percent_Identity=24.2857142857143, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319876, Length=200, Percent_Identity=26, Blast_Score=80, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6319250, Length=298, Percent_Identity=22.4832214765101, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6321502, Length=211, Percent_Identity=25.1184834123223, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323032, Length=237, Percent_Identity=23.2067510548523, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6324410, Length=149, Percent_Identity=24.8322147651007, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584153, Length=363, Percent_Identity=21.4876033057851, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47592; Mature: 47461

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCHHHHCCCCCCCCC
>Mature Secondary Structure 
SNLASGAIAAPAYAAHEEDALYRKIWLRLIPFLFVCYVVSFLDRINIGFAQLQMKQDLG
CCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC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HHHHCCCHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]