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The map label for this gene is codA [H]

Identifier: 73537826

GI number: 73537826

Start: 631851

End: 633149

Strand: Direct

Name: codA [H]

Synonym: Reut_B3993

Alternate gene names: 73537826

Gene position: 631851-633149 (Clockwise)

Preceding gene: 73537825

Following gene: 73537829

Centisome position: 23.18

GC content: 66.36

Gene sequence:

>1299_bases
ATGCTGGAACTGATTTTGCGCCACTGTACGCTGCCGGACGGCCGCACTGGCATCGATATCGGCATCGAAAACGGCCGCAT
CGTCGCCGTGGAGCCCGCGCTTGCCGCGCAGGCTGCGAACGAGATCGATGCCGCCGGGCAACTGGTGACGCCGCCATTCG
TCGACGCGCACTTCCATATGGATTCGACGCTGTCATACGGGCTGCCCCGCGTGAACCAGTCGGGCACGCTGCTCGAAGGC
ATCGCGCTGTGGGGCGAACTGAAGCCGCTGCTGACGCAGGAGGCGCTGGTCGAACGCGCGCTTGCCTACTGCGACTGGGC
CGTGGCGAGAGGATTGCTGGCGATCCGTTCCCATGTCGATGTCTGCGATCCCCGCTTGCTTGCTGTGGAAGCACTGCTGC
ACGTGCGCGAGCGCGTGCGTCCCTACCTCGACCTGCAACTCGTGGCGTTTCCGCAGGACGGCGTGCTGCGCGCGCCGGGC
GCGCTGGAGAACCTTCGCCGCGCGCTCGACATGGGCGTGGAGGTGGTTGGCGGCATCCCTCATTTCGAACGGACCATGGC
GGATGGCGCGGCGTCGGTGCGCCTGCTCTGCGAACTGGCTGCGGAACGCGGATTGCGCGTCGACATGCATTGCGACGAGA
GCGACGACCCGATGTCGCGCCATATCGAAACGCTCGCCAGCGAAACGGTACGGCTGGGCCTGTACGGACGTGTCGCTGGC
TCGCATCTGACGTCGATGCATTCGATGGATAACTACTACGTGTCCAAGCTGCTGCCGCTGATGCGCGAAGCCCGCGTGGC
CGCGATCGCCAACCCGCTGATCAACATCACCTTGCAGGGCCGCCATGACACCTACCCGAAGCGGCGCGGCATGACACGTG
TCCCCGAGTTGCTGGCGGCCGGCGTGCCAGTGGCATTCGGGCATGACTGCGTGATGGACCCGTGGTACAGCTTGGGCAGC
GGCGACATGCTGGAAGTGGCGCACATGGGCCTGCACGTCGGGCAGATGACGGGGCAGGATGCGATGCGCAACTGCTTCGC
CGCCGTGACCACCACGCCTGCGCAGATCCTCGGGCTCGAAGGCTATGGCATCTCGCCGGGCTGCCGGGCGGACCTGATCC
TGCTGCAGGCCCGCGATCCGGTCGAGGCGATCCGCTTGCGCGCCACGCGCCTGAAGGTATTGCGTGCTGGCAAAACCATC
GCCAGCACGCCGGCCGCTACGGCAACGCTGCAATTGCCGGGCCGTCCGACGCAGGTGGATTTCATGGTTTCGCGAGACGG
TACGCAGCGCGGCGACTGA

Upstream 100 bases:

>100_bases
GCTGATTCTGGTGGCGCGCCGGGCCACGTACCCGCAGGCGCTGATGAAACCGTACCGCCGGGGCGAGCGCTGACCTGAAT
CATCAGATTGTGGAGCGACC

Downstream 100 bases:

>100_bases
ACCGTGCAATTTTTCGTTGAAAGGGTGTTGACAATACATTGGTCGCCCAGCATAATCTTGTTCTTCGCATCGCAGCAGAA
ATGCAGCGAAACGAAGCCCA

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MLELILRHCTLPDGRTGIDIGIENGRIVAVEPALAAQAANEIDAAGQLVTPPFVDAHFHMDSTLSYGLPRVNQSGTLLEG
IALWGELKPLLTQEALVERALAYCDWAVARGLLAIRSHVDVCDPRLLAVEALLHVRERVRPYLDLQLVAFPQDGVLRAPG
ALENLRRALDMGVEVVGGIPHFERTMADGAASVRLLCELAAERGLRVDMHCDESDDPMSRHIETLASETVRLGLYGRVAG
SHLTSMHSMDNYYVSKLLPLMREARVAAIANPLINITLQGRHDTYPKRRGMTRVPELLAAGVPVAFGHDCVMDPWYSLGS
GDMLEVAHMGLHVGQMTGQDAMRNCFAAVTTTPAQILGLEGYGISPGCRADLILLQARDPVEAIRLRATRLKVLRAGKTI
ASTPAATATLQLPGRPTQVDFMVSRDGTQRGD

Sequences:

>Translated_432_residues
MLELILRHCTLPDGRTGIDIGIENGRIVAVEPALAAQAANEIDAAGQLVTPPFVDAHFHMDSTLSYGLPRVNQSGTLLEG
IALWGELKPLLTQEALVERALAYCDWAVARGLLAIRSHVDVCDPRLLAVEALLHVRERVRPYLDLQLVAFPQDGVLRAPG
ALENLRRALDMGVEVVGGIPHFERTMADGAASVRLLCELAAERGLRVDMHCDESDDPMSRHIETLASETVRLGLYGRVAG
SHLTSMHSMDNYYVSKLLPLMREARVAAIANPLINITLQGRHDTYPKRRGMTRVPELLAAGVPVAFGHDCVMDPWYSLGS
GDMLEVAHMGLHVGQMTGQDAMRNCFAAVTTTPAQILGLEGYGISPGCRADLILLQARDPVEAIRLRATRLKVLRAGKTI
ASTPAATATLQLPGRPTQVDFMVSRDGTQRGD
>Mature_432_residues
MLELILRHCTLPDGRTGIDIGIENGRIVAVEPALAAQAANEIDAAGQLVTPPFVDAHFHMDSTLSYGLPRVNQSGTLLEG
IALWGELKPLLTQEALVERALAYCDWAVARGLLAIRSHVDVCDPRLLAVEALLHVRERVRPYLDLQLVAFPQDGVLRAPG
ALENLRRALDMGVEVVGGIPHFERTMADGAASVRLLCELAAERGLRVDMHCDESDDPMSRHIETLASETVRLGLYGRVAG
SHLTSMHSMDNYYVSKLLPLMREARVAAIANPLINITLQGRHDTYPKRRGMTRVPELLAAGVPVAFGHDCVMDPWYSLGS
GDMLEVAHMGLHVGQMTGQDAMRNCFAAVTTTPAQILGLEGYGISPGCRADLILLQARDPVEAIRLRATRLKVLRAGKTI
ASTPAATATLQLPGRPTQVDFMVSRDGTQRGD

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=411, Percent_Identity=44.0389294403893, Blast_Score=353, Evalue=2e-98,
Organism=Escherichia coli, GI1786517, Length=400, Percent_Identity=28, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 46884; Mature: 46884

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLELILRHCTLPDGRTGIDIGIENGRIVAVEPALAAQAANEIDAAGQLVTPPFVDAHFHM
CHHHHHHHCCCCCCCCCEEEEECCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCEEECC
DSTLSYGLPRVNQSGTLLEGIALWGELKPLLTQEALVERALAYCDWAVARGLLAIRSHVD
CCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VCDPRLLAVEALLHVRERVRPYLDLQLVAFPQDGVLRAPGALENLRRALDMGVEVVGGIP
CCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEECCHHHHHHHHHHHCCHHHCCCCC
HFERTMADGAASVRLLCELAAERGLRVDMHCDESDDPMSRHIETLASETVRLGLYGRVAG
HHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHEEEEEEHHHHH
SHLTSMHSMDNYYVSKLLPLMREARVAAIANPLINITLQGRHDTYPKRRGMTRVPELLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHCCCHHHHHHHHC
GVPVAFGHDCVMDPWYSLGSGDMLEVAHMGLHVGQMTGQDAMRNCFAAVTTTPAQILGLE
CCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHEECC
GYGISPGCRADLILLQARDPVEAIRLRATRLKVLRAGKTIASTPAATATLQLPGRPTQVD
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCEEE
FMVSRDGTQRGD
EEEECCCCCCCC
>Mature Secondary Structure
MLELILRHCTLPDGRTGIDIGIENGRIVAVEPALAAQAANEIDAAGQLVTPPFVDAHFHM
CHHHHHHHCCCCCCCCCEEEEECCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCEEECC
DSTLSYGLPRVNQSGTLLEGIALWGELKPLLTQEALVERALAYCDWAVARGLLAIRSHVD
CCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VCDPRLLAVEALLHVRERVRPYLDLQLVAFPQDGVLRAPGALENLRRALDMGVEVVGGIP
CCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEECCHHHHHHHHHHHCCHHHCCCCC
HFERTMADGAASVRLLCELAAERGLRVDMHCDESDDPMSRHIETLASETVRLGLYGRVAG
HHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHEEEEEEHHHHH
SHLTSMHSMDNYYVSKLLPLMREARVAAIANPLINITLQGRHDTYPKRRGMTRVPELLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHCCCHHHHHHHHC
GVPVAFGHDCVMDPWYSLGSGDMLEVAHMGLHVGQMTGQDAMRNCFAAVTTTPAQILGLE
CCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHEECC
GYGISPGCRADLILLQARDPVEAIRLRATRLKVLRAGKTIASTPAATATLQLPGRPTQVD
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCEEE
FMVSRDGTQRGD
EEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]