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The map label for this gene is rcsB [H]

Identifier: 73537454

GI number: 73537454

Start: 188538

End: 189197

Strand: Reverse

Name: rcsB [H]

Synonym: Reut_B3619

Alternate gene names: 73537454

Gene position: 189197-188538 (Counterclockwise)

Preceding gene: 73537455

Following gene: 73537451

Centisome position: 6.94

GC content: 62.12

Gene sequence:

>660_bases
ATGACCTTGAGAATCCTGCTGGCCGACGACCACCCCCTTGTCTCCACCGCGGCCCGGGACCTATTGCAGACGCAGGCGGG
ATGGGAGGTGTGCGGCATGGCCACCAGCGCGACAGATTTGCTGTGCTGCGCCCAGGCACTGCGGCCCGATGTGGTAATCA
CCGACTACCACATGCCGGGACCGGGAGATTCCGATGGCATACGGTTGATTTCCACGCTGCGGCGGCACTATCCGGCAATG
GCAGTCATTGTGCTGACGATGATCACCAATCCCATGATCCTGCGCTCGATCCTCAAGTCGCGCGTGCACGGGCTGCTGCT
CAAAGATGCGCCTCCGAGCGAGCTGGTCACCGCGGTCGTCCGCATACAACGGGGCTTCGACTACGTTGGCAAATCAGCAC
TGGAAATCCTGACGCGATCGGACCCGGATAGCCTGATAGAACCCGGCCAGCCCGTTCCCCAACGCATGTCGGTCCGTGAA
ACGGAAGTCATCCGCCTCTACCTGAGCGGGCGCTCGGTCAGCGAGATTGCCGGCATCATGTGCCGCAGCGTCAAGACGAT
CAGCCGCCAGAAAAATTGCGCCATGCAGAAGCTCGGGGCCAACAATGACCGCGAGCTGTTCGAATGCGCTGCGCGCCAGG
GCATCCTTCTGCCCAGCTAG

Upstream 100 bases:

>100_bases
CGATGTTGATGCGTCTTTCGCGCCGCACGCTATACACGCGTGCGGCGATTTTTTGGGACGCAATCACGACGTCTATTCCC
CCACGAGAAGGAACCGCGCC

Downstream 100 bases:

>100_bases
CGCAAATGATCGTGCCGGACGCTTAGTCCGCGTCCGCCATCTCCGCGGCACGCGCCACGGCATCGGCAATGCCGGCCTCC
AATTGGGCAAGGCCTCTCGA

Product: LuxR response regulator receiver

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MTLRILLADDHPLVSTAARDLLQTQAGWEVCGMATSATDLLCCAQALRPDVVITDYHMPGPGDSDGIRLISTLRRHYPAM
AVIVLTMITNPMILRSILKSRVHGLLLKDAPPSELVTAVVRIQRGFDYVGKSALEILTRSDPDSLIEPGQPVPQRMSVRE
TEVIRLYLSGRSVSEIAGIMCRSVKTISRQKNCAMQKLGANNDRELFECAARQGILLPS

Sequences:

>Translated_219_residues
MTLRILLADDHPLVSTAARDLLQTQAGWEVCGMATSATDLLCCAQALRPDVVITDYHMPGPGDSDGIRLISTLRRHYPAM
AVIVLTMITNPMILRSILKSRVHGLLLKDAPPSELVTAVVRIQRGFDYVGKSALEILTRSDPDSLIEPGQPVPQRMSVRE
TEVIRLYLSGRSVSEIAGIMCRSVKTISRQKNCAMQKLGANNDRELFECAARQGILLPS
>Mature_218_residues
TLRILLADDHPLVSTAARDLLQTQAGWEVCGMATSATDLLCCAQALRPDVVITDYHMPGPGDSDGIRLISTLRRHYPAMA
VIVLTMITNPMILRSILKSRVHGLLLKDAPPSELVTAVVRIQRGFDYVGKSALEILTRSDPDSLIEPGQPVPQRMSVRET
EVIRLYLSGRSVSEIAGIMCRSVKTISRQKNCAMQKLGANNDRELFECAARQGILLPS

Specific function: Also stimulates ftsZ expression. This suggests that rcsB is a regulator implicated in the regulation of more than one cellular function [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788546, Length=203, Percent_Identity=38.9162561576355, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1788222, Length=215, Percent_Identity=27.906976744186, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788712, Length=213, Percent_Identity=25.3521126760563, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790102, Length=204, Percent_Identity=28.4313725490196, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24034; Mature: 23903

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRILLADDHPLVSTAARDLLQTQAGWEVCGMATSATDLLCCAQALRPDVVITDYHMPG
CEEEEEEECCCCHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCC
PGDSDGIRLISTLRRHYPAMAVIVLTMITNPMILRSILKSRVHGLLLKDAPPSELVTAVV
CCCCHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHEEEECCCCHHHHHHHHH
RIQRGFDYVGKSALEILTRSDPDSLIEPGQPVPQRMSVRETEVIRLYLSGRSVSEIAGIM
HHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHCCCHHHEEEEEECCCCHHHHHHHH
CRSVKTISRQKNCAMQKLGANNDRELFECAARQGILLPS
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TLRILLADDHPLVSTAARDLLQTQAGWEVCGMATSATDLLCCAQALRPDVVITDYHMPG
EEEEEEECCCCHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCC
PGDSDGIRLISTLRRHYPAMAVIVLTMITNPMILRSILKSRVHGLLLKDAPPSELVTAVV
CCCCHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHEEEECCCCHHHHHHHHH
RIQRGFDYVGKSALEILTRSDPDSLIEPGQPVPQRMSVRETEVIRLYLSGRSVSEIAGIM
HHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHCCCHHHEEEEEECCCCHHHHHHHH
CRSVKTISRQKNCAMQKLGANNDRELFECAARQGILLPS
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]