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The map label for this gene is tctD [H]

Identifier: 73543119

GI number: 73543119

Start: 3777295

End: 3777972

Strand: Reverse

Name: tctD [H]

Synonym: Reut_A3437

Alternate gene names: 73543119

Gene position: 3777972-3777295 (Counterclockwise)

Preceding gene: 73543121

Following gene: 73543118

Centisome position: 99.25

GC content: 69.17

Gene sequence:

>678_bases
ATGCGCATTCTGCTGGTGGAAGATGAAGTCGAACTGGCGCGCTGGGTTGCCCGCGCGCTGGAGCAGGGCGGCTTCGTGAT
CGAACACGTGGGCGATGGCCTGCAGGCCGAGGCGCGGCTTGTGGCCGAAGAGTACGACGTGGTCGTGCTTGACCTGCGCC
TGCCCGGCAAGGATGGCCTGGCCGTGCTCAAGGCCATGCGCGCGCGCGACGACCGCACGCCGGTGCTGATCCTGACCGCG
CAGGACACGCTCGACGAACGCGTGCGCGGCCTGAACCTCGGCGCCGACGACTACCTGCCCAAGCCGTTCGCGATTGCCGA
ACTGGAAGCCCGCATCCTCGCGCTGATCCGCCGCAGCCGCGGCCGCGCGCACCCGCGCCTGCAATGCGGCACGCTGGTGT
TCGATGGGGAGTCCCGCGGCTTTACGCTCGACGGCCAGCCGCTCGCGCTGACGCCGCGCGAATCGACGCTGCTCGGTGCG
CTGCTCGCACGCAGCGGCCAGCCGCTCACCAAGGCCCAGTTGCTCGACAAGGTGTTTTCGCTCGACGCCGATGTCAGCCC
CGATGCCATCGAGGTGCTCGTGTACCGCCTGCGCAAGAAACTGGCCGGGCATGGCGTGACGATCGTCACGCTGCGTGGCT
TCGGCTACCTGCTCGAGCCTGAGACACCGGCCGCCTGA

Upstream 100 bases:

>100_bases
GGGCGCGACACGCGCCGGGAACGCCGGTAATGGCGGGGCGGGGGTATTATAGGCGCCCGCGTCCCATGGACCGCACGATC
AAAAATGGAGGAGAACCAGC

Downstream 100 bases:

>100_bases
CATGTGGCTCCGCAAGCTGCGCCACGGCGCGCGGCGCCCGATCCCGCTGTGGCGGCGCGGCAGCCTGCGCCGCCAGTTGC
TTCTGCTGCTGGTGCCCGCG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MRILLVEDEVELARWVARALEQGGFVIEHVGDGLQAEARLVAEEYDVVVLDLRLPGKDGLAVLKAMRARDDRTPVLILTA
QDTLDERVRGLNLGADDYLPKPFAIAELEARILALIRRSRGRAHPRLQCGTLVFDGESRGFTLDGQPLALTPRESTLLGA
LLARSGQPLTKAQLLDKVFSLDADVSPDAIEVLVYRLRKKLAGHGVTIVTLRGFGYLLEPETPAA

Sequences:

>Translated_225_residues
MRILLVEDEVELARWVARALEQGGFVIEHVGDGLQAEARLVAEEYDVVVLDLRLPGKDGLAVLKAMRARDDRTPVLILTA
QDTLDERVRGLNLGADDYLPKPFAIAELEARILALIRRSRGRAHPRLQCGTLVFDGESRGFTLDGQPLALTPRESTLLGA
LLARSGQPLTKAQLLDKVFSLDADVSPDAIEVLVYRLRKKLAGHGVTIVTLRGFGYLLEPETPAA
>Mature_225_residues
MRILLVEDEVELARWVARALEQGGFVIEHVGDGLQAEARLVAEEYDVVVLDLRLPGKDGLAVLKAMRARDDRTPVLILTA
QDTLDERVRGLNLGADDYLPKPFAIAELEARILALIRRSRGRAHPRLQCGTLVFDGESRGFTLDGQPLALTPRESTLLGA
LLARSGQPLTKAQLLDKVFSLDADVSPDAIEVLVYRLRKKLAGHGVTIVTLRGFGYLLEPETPAA

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=43.5779816513761, Blast_Score=171, Evalue=4e-44,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=40.8256880733945, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=37.3873873873874, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=35.3211009174312, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=33.3333333333333, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=30.7692307692308, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=36.1990950226244, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=37.9912663755458, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=33.0316742081448, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=32.4324324324324, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=30.4932735426009, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=30.6666666666667, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=29.4871794871795, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=28.82096069869, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790299, Length=125, Percent_Identity=38.4, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=37.962962962963, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790437, Length=110, Percent_Identity=32.7272727272727, Blast_Score=63, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=167, Percent_Identity=26.9461077844311, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24650; Mature: 24650

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLVEDEVELARWVARALEQGGFVIEHVGDGLQAEARLVAEEYDVVVLDLRLPGKDGL
CEEEEECCHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCHH
AVLKAMRARDDRTPVLILTAQDTLDERVRGLNLGADDYLPKPFAIAELEARILALIRRSR
HHHHHHHHCCCCCCEEEEEECHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
GRAHPRLQCGTLVFDGESRGFTLDGQPLALTPRESTLLGALLARSGQPLTKAQLLDKVFS
CCCCCCEEEEEEEECCCCCCEEECCCCEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
LDADVSPDAIEVLVYRLRKKLAGHGVTIVTLRGFGYLLEPETPAA
CCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEECCCCCCC
>Mature Secondary Structure
MRILLVEDEVELARWVARALEQGGFVIEHVGDGLQAEARLVAEEYDVVVLDLRLPGKDGL
CEEEEECCHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCHH
AVLKAMRARDDRTPVLILTAQDTLDERVRGLNLGADDYLPKPFAIAELEARILALIRRSR
HHHHHHHHCCCCCCEEEEEECHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
GRAHPRLQCGTLVFDGESRGFTLDGQPLALTPRESTLLGALLARSGQPLTKAQLLDKVFS
CCCCCCEEEEEEEECCCCCCEEECCCCEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
LDADVSPDAIEVLVYRLRKKLAGHGVTIVTLRGFGYLLEPETPAA
CCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]