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The map label for this gene is mdtA [H]

Identifier: 73543106

GI number: 73543106

Start: 3758718

End: 3759956

Strand: Direct

Name: mdtA [H]

Synonym: Reut_A3424

Alternate gene names: 73543106

Gene position: 3758718-3759956 (Clockwise)

Preceding gene: 73543105

Following gene: 73543107

Centisome position: 98.74

GC content: 67.55

Gene sequence:

>1239_bases
ATGAAGACAGACAGGATCGACCAGCCCAAAGGGTTTGTCGACAGCAACTGGAGCGCGTCCACGGGAACCGGTCGGGGCCG
GGTGTCGCCGTGGGCGGTGGTGGTGACTGTGCTGGTGCTTGCCGGCCTGGGGTGGTTTGCCTGGCGTACCTGGTTTGCCC
CAAAGCCCGTTGCCAAGGGGCCGGCGCCCGTGGCGGTCGCCACCGCGCTCGTGCAGCAGGGTGACGTGCCGCTGCAGTTC
ACGGCTAACGGCAATGTGACGGCGTTATCCACAGTCGAAGTGCGCCCACAGGTCTCGAGCACGGTCCGCACCGTCCATAT
CAAGGAAGGCCAGACCGTGAAGCCGGGCGACCTGCTGTTCTCGCTCGACACGCGCATGGACGAAGCCAACCTGGCCAAGG
CCCAGGCGCAGTTGCTGCGGGACCAGGCCGACCTGTCCGATGCGCGCCGCAACCTGTCGCGCAGCAAGGAACTGCTGGAG
CGCAATTTCATCTCCAAGAGCGCGGTGGATACGGCCCAGGCCAAGGTGGACGGCTTCGAGGCTACTATCCGCGCCGACCA
GGCGGCCATCGAGGCCAGCCGCGTTGCGGTCAGCTATGGCGCGATCCGCGCGAGCATCGGCGGGCGTACCGGCGTGATCA
ACGTGTTCCCGGGATCGATGGTGCTGCCTAACAGTACCGGGCCGATGGTGACCATCGCCCAGATCCAGCCGATCGCGGTG
ACCTTCAGCCTCCCCGAGCGGCAGCTCGCCTCGTTGCGCGACGCTCTGCGCAACGGCCCCGTGCAGGTCACGGCCCAGCC
CAACGACGGCAGCAAGACGCCGGTGACCGGCAAGATCACGTTCATCGATAACACCGTCGATCCGCAGTACGGCACCATCC
GCGTCAAGGCGCAGTTCGACAACGAGGAGCAGCGCCTGTGGCCAGGTACGTACGCCAATGTCAGCGCCGTGGTCCAGACG
TTGAAGGACGCGCTGTCGGTGCCGCCGCAGGCCGTGGTGACGGGTCCGGAAGGACGCTTCGTCTACACAGTGCAGCCTGA
CAACAAGGTCGCCCGCGTGCCCGTGAAGATGGTGACCACCACCGCCACGTCGGCGGTGATCGAGGGCGTGCAGCCCGGCA
CGCGCGTGGTCGTCGAAGGCACGCAGAACCTGCGTCCCGGCACCGTGGTACGAGAGGTTCCGCGCGTCCCTTCCGCCTCC
GCCGGGGCCGCGAGCACGCCCGCCGCCCAGGGGCACTGA

Upstream 100 bases:

>100_bases
CCGCCCGGCCCCCGGGCCGCCCGTCGTGGGCGGCCGCGGCAGGAACAGAGGCAGGACGTCCCCGGGGAGGGCGCGTTGCG
GCTAAGAGGGTCCACACAAG

Downstream 100 bases:

>100_bases
GCCATGACGCTGTCCGAGCTCTGTATCCGCCGTCCGGTGATGACGGTGCTGCTGTGCATTGCCGTCATCGTGACCGGCAT
CGTGCTGTACCCGACCATCC

Product: secretion protein HlyD

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MKTDRIDQPKGFVDSNWSASTGTGRGRVSPWAVVVTVLVLAGLGWFAWRTWFAPKPVAKGPAPVAVATALVQQGDVPLQF
TANGNVTALSTVEVRPQVSSTVRTVHIKEGQTVKPGDLLFSLDTRMDEANLAKAQAQLLRDQADLSDARRNLSRSKELLE
RNFISKSAVDTAQAKVDGFEATIRADQAAIEASRVAVSYGAIRASIGGRTGVINVFPGSMVLPNSTGPMVTIAQIQPIAV
TFSLPERQLASLRDALRNGPVQVTAQPNDGSKTPVTGKITFIDNTVDPQYGTIRVKAQFDNEEQRLWPGTYANVSAVVQT
LKDALSVPPQAVVTGPEGRFVYTVQPDNKVARVPVKMVTTTATSAVIEGVQPGTRVVVEGTQNLRPGTVVREVPRVPSAS
AGAASTPAAQGH

Sequences:

>Translated_412_residues
MKTDRIDQPKGFVDSNWSASTGTGRGRVSPWAVVVTVLVLAGLGWFAWRTWFAPKPVAKGPAPVAVATALVQQGDVPLQF
TANGNVTALSTVEVRPQVSSTVRTVHIKEGQTVKPGDLLFSLDTRMDEANLAKAQAQLLRDQADLSDARRNLSRSKELLE
RNFISKSAVDTAQAKVDGFEATIRADQAAIEASRVAVSYGAIRASIGGRTGVINVFPGSMVLPNSTGPMVTIAQIQPIAV
TFSLPERQLASLRDALRNGPVQVTAQPNDGSKTPVTGKITFIDNTVDPQYGTIRVKAQFDNEEQRLWPGTYANVSAVVQT
LKDALSVPPQAVVTGPEGRFVYTVQPDNKVARVPVKMVTTTATSAVIEGVQPGTRVVVEGTQNLRPGTVVREVPRVPSAS
AGAASTPAAQGH
>Mature_412_residues
MKTDRIDQPKGFVDSNWSASTGTGRGRVSPWAVVVTVLVLAGLGWFAWRTWFAPKPVAKGPAPVAVATALVQQGDVPLQF
TANGNVTALSTVEVRPQVSSTVRTVHIKEGQTVKPGDLLFSLDTRMDEANLAKAQAQLLRDQADLSDARRNLSRSKELLE
RNFISKSAVDTAQAKVDGFEATIRADQAAIEASRVAVSYGAIRASIGGRTGVINVFPGSMVLPNSTGPMVTIAQIQPIAV
TFSLPERQLASLRDALRNGPVQVTAQPNDGSKTPVTGKITFIDNTVDPQYGTIRVKAQFDNEEQRLWPGTYANVSAVVQT
LKDALSVPPQAVVTGPEGRFVYTVQPDNKVARVPVKMVTTTATSAVIEGVQPGTRVVVEGTQNLRPGTVVREVPRVPSAS
AGAASTPAAQGH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=344, Percent_Identity=36.9186046511628, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI1786668, Length=328, Percent_Identity=32.0121951219512, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1789929, Length=335, Percent_Identity=28.6567164179104, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1789665, Length=329, Percent_Identity=29.483282674772, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI87081796, Length=244, Percent_Identity=27.8688524590164, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87081951, Length=185, Percent_Identity=28.6486486486486, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43745; Mature: 43745

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTDRIDQPKGFVDSNWSASTGTGRGRVSPWAVVVTVLVLAGLGWFAWRTWFAPKPVAKG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCC
PAPVAVATALVQQGDVPLQFTANGNVTALSTVEVRPQVSSTVRTVHIKEGQTVKPGDLLF
CCCHHHHHHHHHCCCCCEEEECCCCEEEEEEEEECCCCCCCEEEEEECCCCEECCCCEEE
SLDTRMDEANLAKAQAQLLRDQADLSDARRNLSRSKELLERNFISKSAVDTAQAKVDGFE
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
ATIRADQAAIEASRVAVSYGAIRASIGGRTGVINVFPGSMVLPNSTGPMVTIAQIQPIAV
EEEEHHHHHHHHHHEEEEHHHEEEECCCCCCEEEECCCCEECCCCCCCEEEEEEECEEEE
TFSLPERQLASLRDALRNGPVQVTAQPNDGSKTPVTGKITFIDNTVDPQYGTIRVKAQFD
EEECCHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEEEECCCCCCCCEEEEEEECC
NEEQRLWPGTYANVSAVVQTLKDALSVPPQAVVTGPEGRFVYTVQPDNKVARVPVKMVTT
CCCCEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECCCCCEEECEEEEEEH
TATSAVIEGVQPGTRVVVEGTQNLRPGTVVREVPRVPSASAGAASTPAAQGH
HHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKTDRIDQPKGFVDSNWSASTGTGRGRVSPWAVVVTVLVLAGLGWFAWRTWFAPKPVAKG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCC
PAPVAVATALVQQGDVPLQFTANGNVTALSTVEVRPQVSSTVRTVHIKEGQTVKPGDLLF
CCCHHHHHHHHHCCCCCEEEECCCCEEEEEEEEECCCCCCCEEEEEECCCCEECCCCEEE
SLDTRMDEANLAKAQAQLLRDQADLSDARRNLSRSKELLERNFISKSAVDTAQAKVDGFE
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
ATIRADQAAIEASRVAVSYGAIRASIGGRTGVINVFPGSMVLPNSTGPMVTIAQIQPIAV
EEEEHHHHHHHHHHEEEEHHHEEEECCCCCCEEEECCCCEECCCCCCCEEEEEEECEEEE
TFSLPERQLASLRDALRNGPVQVTAQPNDGSKTPVTGKITFIDNTVDPQYGTIRVKAQFD
EEECCHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEEEECCCCCCCCEEEEEEECC
NEEQRLWPGTYANVSAVVQTLKDALSVPPQAVVTGPEGRFVYTVQPDNKVARVPVKMVTT
CCCCEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECCCCCEEECEEEEEEH
TATSAVIEGVQPGTRVVVEGTQNLRPGTVVREVPRVPSASAGAASTPAAQGH
HHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA