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The map label for this gene is fmt [H]

Identifier: 73543089

GI number: 73543089

Start: 3738278

End: 3739273

Strand: Reverse

Name: fmt [H]

Synonym: Reut_A3407

Alternate gene names: 73543089

Gene position: 3739273-3738278 (Counterclockwise)

Preceding gene: 73543090

Following gene: 73543088

Centisome position: 98.23

GC content: 69.28

Gene sequence:

>996_bases
ATGTCCGAAGCCCAGTCCCTGCGTGTCGCCTTTGCCGGCACGCCCGAATTCGCGCGTGTCGCGCTTGAAGCCATCCATGC
CGCCGGTTATCCGGTTGTCGCGGTGCTCAGCCAGCCGGATCGGCCGGCGGGCCGCGGCATGCAACTGCAGGCAAGCCCCG
TCAAGCAGTACGCAGTCGCCAATGCCCTGGAGCCGGTGCTGCAGCCGCGTTCGCTGCGCCGTACGGGAAAGTATCCCGAG
GATGCCGCTACAGCCATCGACGCGCTCGCGCAGACCGCGCCCGACGTGATGGTCGTGGCTGCCTACGGCCTGATCCTGCC
GGCTGAAGTGCTGACGCTGCCGCGGCTCGGCTGCCTGAACATCCACGCTTCGCTGCTGCCGCGCTGGCGCGGCGCCGCCC
CGATCCACCGCGCGATCGAGGCTGGCGACGCCGAGACCGGCATCACGCTGATGCAGATGGACGAAGGCCTGGACACCGGC
GCCATGCTGTCGCGCGAAGCCGTACCTATTGCAGCGGATGACAGCACCGGCTCGCTTCATGACAAGCTCGCCGCACTCGG
CGGCCGCATGATCGTCGAGGCGCTGCGCAAGCTCGCCGCGGGCGAAACACTGCCTGCCACGCCGCAGCCCGAAGCCGGCA
TCACCTACGCCGAGAAGATCGGCAAGGACGAAGCGCCACTGGATCTGCGCCGCCCGGCCGCTGAACTTGCCAGCCAGGTC
CGCGCGTTCAACCCGTTCCCGGGCGCCACGCTGCAGCTCGACAACACGGTGATCAAGTGCTGGCAAGCCGTGCCGCTGTC
CGCCGGCACCAGCCTGCCGCACCCGGCGGGCACGGTGCTGGCCTCGGACGCCAGCGGCGTGATCATCGCCTGTGGCAACG
GCAGTGCGCTGCAGGTCACCGAGTTGCAGAAACCCGGCGGCCGCCGCCAGCCGGCGCAACAATTCCTGCAAGGCACGCCG
CTGCTGCCGGGAACGCGCTTTGTGGTGCCTGCATAA

Upstream 100 bases:

>100_bases
GCTATCGTTATGGCTTCCGAAGTCAAAAACGTACCGGCCGCTATGCGGCCGGTTCTGCTTTTGGCCCTGCATTCCTGGTC
CTGCATTCAGGGAGCCCGCC

Downstream 100 bases:

>100_bases
AACGCGGGCGGCGGGCACGATCGTGCACTCCCTGCCGCGCCTGACGCAGCGCCGGACTCGCCGAGCGGTGTGAAACCGTT
GAATTTTCAGCGATTCACCC

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSEAQSLRVAFAGTPEFARVALEAIHAAGYPVVAVLSQPDRPAGRGMQLQASPVKQYAVANALEPVLQPRSLRRTGKYPE
DAATAIDALAQTAPDVMVVAAYGLILPAEVLTLPRLGCLNIHASLLPRWRGAAPIHRAIEAGDAETGITLMQMDEGLDTG
AMLSREAVPIAADDSTGSLHDKLAALGGRMIVEALRKLAAGETLPATPQPEAGITYAEKIGKDEAPLDLRRPAAELASQV
RAFNPFPGATLQLDNTVIKCWQAVPLSAGTSLPHPAGTVLASDASGVIIACGNGSALQVTELQKPGGRRQPAQQFLQGTP
LLPGTRFVVPA

Sequences:

>Translated_331_residues
MSEAQSLRVAFAGTPEFARVALEAIHAAGYPVVAVLSQPDRPAGRGMQLQASPVKQYAVANALEPVLQPRSLRRTGKYPE
DAATAIDALAQTAPDVMVVAAYGLILPAEVLTLPRLGCLNIHASLLPRWRGAAPIHRAIEAGDAETGITLMQMDEGLDTG
AMLSREAVPIAADDSTGSLHDKLAALGGRMIVEALRKLAAGETLPATPQPEAGITYAEKIGKDEAPLDLRRPAAELASQV
RAFNPFPGATLQLDNTVIKCWQAVPLSAGTSLPHPAGTVLASDASGVIIACGNGSALQVTELQKPGGRRQPAQQFLQGTP
LLPGTRFVVPA
>Mature_330_residues
SEAQSLRVAFAGTPEFARVALEAIHAAGYPVVAVLSQPDRPAGRGMQLQASPVKQYAVANALEPVLQPRSLRRTGKYPED
AATAIDALAQTAPDVMVVAAYGLILPAEVLTLPRLGCLNIHASLLPRWRGAAPIHRAIEAGDAETGITLMQMDEGLDTGA
MLSREAVPIAADDSTGSLHDKLAALGGRMIVEALRKLAAGETLPATPQPEAGITYAEKIGKDEAPLDLRRPAAELASQVR
AFNPFPGATLQLDNTVIKCWQAVPLSAGTSLPHPAGTVLASDASGVIIACGNGSALQVTELQKPGGRRQPAQQFLQGTPL
LPGTRFVVPA

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Homo sapiens, GI21614513, Length=324, Percent_Identity=27.7777777777778, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI238814322, Length=318, Percent_Identity=25.7861635220126, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI164663775, Length=269, Percent_Identity=34.2007434944238, Blast_Score=108, Evalue=6e-24,
Organism=Escherichia coli, GI1789683, Length=327, Percent_Identity=47.0948012232416, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI1788589, Length=309, Percent_Identity=28.4789644012945, Blast_Score=118, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI133930964, Length=328, Percent_Identity=25, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319458, Length=363, Percent_Identity=24.2424242424242, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45550868, Length=313, Percent_Identity=27.7955271565495, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI28571984, Length=226, Percent_Identity=30.0884955752212, Blast_Score=104, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24585660, Length=249, Percent_Identity=25.7028112449799, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24582400, Length=89, Percent_Identity=39.3258426966292, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR001555
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 34522; Mature: 34391

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAQSLRVAFAGTPEFARVALEAIHAAGYPVVAVLSQPDRPAGRGMQLQASPVKQYAVA
CCCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCHHHHHHHH
NALEPVLQPRSLRRTGKYPEDAATAIDALAQTAPDVMVVAAYGLILPAEVLTLPRLGCLN
HHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHH
IHASLLPRWRGAAPIHRAIEAGDAETGITLMQMDEGLDTGAMLSREAVPIAADDSTGSLH
HHHHHCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHCCCCEEEECCCCCHHH
DKLAALGGRMIVEALRKLAAGETLPATPQPEAGITYAEKIGKDEAPLDLRRPAAELASQV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHCCHHHHHHHH
RAFNPFPGATLQLDNTVIKCWQAVPLSAGTSLPHPAGTVLASDASGVIIACGNGSALQVT
HHCCCCCCCEEEECHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCEEEEECCCCEEEEE
ELQKPGGRRQPAQQFLQGTPLLPGTRFVVPA
ECCCCCCCCCHHHHHHCCCCCCCCCCEECCC
>Mature Secondary Structure 
SEAQSLRVAFAGTPEFARVALEAIHAAGYPVVAVLSQPDRPAGRGMQLQASPVKQYAVA
CCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCHHHHHHHH
NALEPVLQPRSLRRTGKYPEDAATAIDALAQTAPDVMVVAAYGLILPAEVLTLPRLGCLN
HHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHH
IHASLLPRWRGAAPIHRAIEAGDAETGITLMQMDEGLDTGAMLSREAVPIAADDSTGSLH
HHHHHCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHCCCCEEEECCCCCHHH
DKLAALGGRMIVEALRKLAAGETLPATPQPEAGITYAEKIGKDEAPLDLRRPAAELASQV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHCCHHHHHHHH
RAFNPFPGATLQLDNTVIKCWQAVPLSAGTSLPHPAGTVLASDASGVIIACGNGSALQVT
HHCCCCCCCEEEECHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCEEEEECCCCEEEEE
ELQKPGGRRQPAQQFLQGTPLLPGTRFVVPA
ECCCCCCCCCHHHHHHCCCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA