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The map label for this gene is tctD [H]

Identifier: 73543071

GI number: 73543071

Start: 3715911

End: 3716615

Strand: Direct

Name: tctD [H]

Synonym: Reut_A3389

Alternate gene names: 73543071

Gene position: 3715911-3716615 (Clockwise)

Preceding gene: 73543070

Following gene: 73543072

Centisome position: 97.62

GC content: 68.51

Gene sequence:

>705_bases
ATGCGTATCCTGCTGATCGAAGACGACCGCCAGATCGCGAGCGGCGTCGAAGCCGGCCTGACCCGTGCCGGCCACCAGGT
GCGCGTGGTCCATGACGGCGTCTACGCCACCGAGCACCTGCTGCGCGAGCAGCATGACCTTGTCATCCTCGACCTGGGCC
TGCCCGGTATTGACGGCATGACGCTGCTCGCGCGCTACCGCGCCCGCAACCGCACCACGCCCGTCATCATCCTGACCGCG
CGCGACGAGCTCGAAGACAAGCTTTCCGGCCTGAACGCCGGCGCCGACGACTACCTCGTCAAGCCATTCGCACTGCCCGA
GCTGGAGGCCCGCGTGCGTGTGCTGTTGCGCCGCAGCCAGCACGGCGAAGCCGTACCCGATCGCGACGTGCGCCTGGGCC
GGCTGCGCCTGTCCGGCAACGATCGCCGCATGTTCATCGACGGCAAGCCGCTGGAACTGTCGCCGCGCGAGTTCGCGGTG
CTGGAACTGCTGCTGCAGCGCCAGGGCCGTGTGGTCAGCAAGGCACAGCTCCAGGATCACCTGGCCACCTTCGCCCACCC
GGCCGGCGAAGGCGGCGACACGGTCGGCGACACCGCCATCGAAGTCTATGTGCACCGCGTGCGCAAGAAGCTCGAGGAAA
GCGACGTCGAGATCGTCACGGTACGCGGCTTCGGCTACCTGCTGCAGGCCCGCGCCGGCCAATGA

Upstream 100 bases:

>100_bases
TGGATCGCGGTTCCGCGTGTGCGCCACGCCGCGCCTGCCGCCTCCTGTCTTCCTTCCCGGCTGATCCAGCCATGTCCGAC
GTCCTGCCCGAACTGCCGCC

Downstream 100 bases:

>100_bases
GCACGCGCCCGCGGCGCCGGCCGGCTGACTGAAATCCAGCGCCATGTGGCCGCGAACCCGCTCCTCACGTACCAACACCG
ATTTCGCCGAGTCGACGCAG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MRILLIEDDRQIASGVEAGLTRAGHQVRVVHDGVYATEHLLREQHDLVILDLGLPGIDGMTLLARYRARNRTTPVIILTA
RDELEDKLSGLNAGADDYLVKPFALPELEARVRVLLRRSQHGEAVPDRDVRLGRLRLSGNDRRMFIDGKPLELSPREFAV
LELLLQRQGRVVSKAQLQDHLATFAHPAGEGGDTVGDTAIEVYVHRVRKKLEESDVEIVTVRGFGYLLQARAGQ

Sequences:

>Translated_234_residues
MRILLIEDDRQIASGVEAGLTRAGHQVRVVHDGVYATEHLLREQHDLVILDLGLPGIDGMTLLARYRARNRTTPVIILTA
RDELEDKLSGLNAGADDYLVKPFALPELEARVRVLLRRSQHGEAVPDRDVRLGRLRLSGNDRRMFIDGKPLELSPREFAV
LELLLQRQGRVVSKAQLQDHLATFAHPAGEGGDTVGDTAIEVYVHRVRKKLEESDVEIVTVRGFGYLLQARAGQ
>Mature_234_residues
MRILLIEDDRQIASGVEAGLTRAGHQVRVVHDGVYATEHLLREQHDLVILDLGLPGIDGMTLLARYRARNRTTPVIILTA
RDELEDKLSGLNAGADDYLVKPFALPELEARVRVLLRRSQHGEAVPDRDVRLGRLRLSGNDRRMFIDGKPLELSPREFAV
LELLLQRQGRVVSKAQLQDHLATFAHPAGEGGDTVGDTAIEVYVHRVRKKLEESDVEIVTVRGFGYLLQARAGQ

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=44.2982456140351, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1790552, Length=232, Percent_Identity=39.6551724137931, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1786784, Length=237, Percent_Identity=34.5991561181435, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787375, Length=237, Percent_Identity=35.4430379746835, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI87082012, Length=232, Percent_Identity=36.2068965517241, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=34.1880341880342, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=34.7826086956522, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786599, Length=235, Percent_Identity=34.0425531914894, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1788394, Length=242, Percent_Identity=33.0578512396694, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI2367329, Length=236, Percent_Identity=36.0169491525424, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786911, Length=235, Percent_Identity=33.1914893617021, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI145693140, Length=244, Percent_Identity=29.5081967213115, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=30.1724137931034, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=29.1845493562232, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790299, Length=131, Percent_Identity=32.824427480916, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=34.2592592592593, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790437, Length=108, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787487, Length=101, Percent_Identity=32.6732673267327, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI48994928, Length=116, Percent_Identity=34.4827586206897, Blast_Score=60, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=117, Percent_Identity=32.4786324786325, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26114; Mature: 26114

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLIEDDRQIASGVEAGLTRAGHQVRVVHDGVYATEHLLREQHDLVILDLGLPGIDGM
CEEEEEECCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCEEEEEECCCCCCHH
TLLARYRARNRTTPVIILTARDELEDKLSGLNAGADDYLVKPFALPELEARVRVLLRRSQ
HHHHHHHHCCCCCCEEEEECCHHHHHHHHCCCCCCCCCEECCCCCCHHHHHHHHHHHHCC
HGEAVPDRDVRLGRLRLSGNDRRMFIDGKPLELSPREFAVLELLLQRQGRVVSKAQLQDH
CCCCCCCCCCEEEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
LATFAHPAGEGGDTVGDTAIEVYVHRVRKKLEESDVEIVTVRGFGYLLQARAGQ
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCEEEEECCCC
>Mature Secondary Structure
MRILLIEDDRQIASGVEAGLTRAGHQVRVVHDGVYATEHLLREQHDLVILDLGLPGIDGM
CEEEEEECCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCEEEEEECCCCCCHH
TLLARYRARNRTTPVIILTARDELEDKLSGLNAGADDYLVKPFALPELEARVRVLLRRSQ
HHHHHHHHCCCCCCEEEEECCHHHHHHHHCCCCCCCCCEECCCCCCHHHHHHHHHHHHCC
HGEAVPDRDVRLGRLRLSGNDRRMFIDGKPLELSPREFAVLELLLQRQGRVVSKAQLQDH
CCCCCCCCCCEEEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
LATFAHPAGEGGDTVGDTAIEVYVHRVRKKLEESDVEIVTVRGFGYLLQARAGQ
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]